Clinical trials: Intubation Conditions
Morbid Obesity
McGrath Videolaryngoscopy and Direct Laryngoscopy in Morbidly Obese Patients
Our goal is to compare conventional direct laryngoscopy using a Macintosh blade with the McGrath videolaryngoscope for endotracheal intubation in very morbidly obese patients undergoing non-cardiac surgery.
- Trial name
- NCT03467048
- Testing
- McGrath videolaryngoscopy, Direct laryngoscopy
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- The Cleveland Clinic
Premedication, Endotracheal Intubation
Premedication Trial for Tracheal Intubation of the NEOnate
Multicenter double blind randomized controlled trial comparing "atropine+propofol" vs "atropine+atracurium+sufentanil" as a premedication prior to endotracheal intubation of the neonate.
- Trial name
- PRETTINEO (NCT01490580)
- Testing
- atropine+ propofol, atropine + atracurium + sufentanil
- Where
- 6 sites in France
- Volunteers
- 173 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Postoperative Pain
Optimal Sevoflurane Concentration for Intubation in Combination of Clincal Remifentanil Doses
Intubation is a procedure that requires well relaxed muscles while general anesthesia is performed. In order to get adequate muscle relaxation, remifentanil, sevoflurane or both agents in combination have been reported as they…
- Trial name
- NCT02440204
- Testing
- Intubation, Remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Severance Hospital
Acute Respiratory Failure
DirEct Versus VIdeo LaryngosCopE Trial
Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States.
- Trial name
- DEVICE (NCT05239195)
- Testing
- Video Laryngoscope, Direct Laryngoscope
- Where
- 12 sites in United States
- Volunteers
- 1,420 people
- Sponsor
- Vanderbilt University Medical Center
Mechanical Ventilation Complication
Clinical Study of the Endotracheal Tube Used in Prone Position Ventilation Condition
In this study, the investigators adopt the special endotracheal tube to those patients at prone posture during the operation,or those with acute respiratory distress syndrome in the intensive care unit(ICU), so that the…
- Trial name
- NCT02449356
- Testing
- prone position endotracheal tube(PPT)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wangyuan Zou
Post Operative Sore Throat, Dysphagia
Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique
The purpose of this study is to test whether the incidence of sore throat and other tracheal co-morbidities such as dysphagia and hoarseness can be lessened by use of a cuff manometer at the beginning of surgery to inflate to the…
- Conditions
- Post Operative Sore Throat, Dysphagia, Hoarseness
- Trial name
- NCT01305265
- Testing
- cuff manometer
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anesthesia
Ambu AuraGain and Teleflex LMA Protector Fiberoptic Assessments in Elective Patients
Participant is being asked to take part in this study because participant is going to have surgery that requires general anesthesia (in which participant is unconscious for the procedure).
- Trial name
- NCT02724956
- Testing
- Ambu AuraGain, Teleflex LMA Protector, Ambu aScope
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Coughing
Effect of Single-dose Dexmedetomidine on Airway Reflex in Adult With Oral Intubation After Thyroidectomy
Coughing during emergence from general anaesthesia may lead to dangerous effects including laryngospasm, detrimental haemodynamic changes.
- Trial name
- NCT01774305
- Testing
- Dexmedetomidine, Saline
- Where
- South Korea
- Volunteers
- 141 people
- Sponsor
- Yonsei University
Anesthesia
Intubation Conditions Achieved With Rapid Co-administration of Rocuronium and Propofol Versus Classical Induction
The purpose of this study is to assess and compare the conditions for tracheal intubation obtained with Modified Time Principle Induction (MTPI) and that obtained with classic induction (CI).
- Trial name
- NCT05509192
- Testing
- MTPI, Classic Induction
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cardiopulmonary Arrest, Respiratory Arrest
Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial
Patients who are having problems breathing sometimes require placement of a breathing tube in their mouth and windpipe. The purpose of this breathing tube is to save the patient's life.
- Trial name
- EvK (NCT02643381)
- Testing
- Etomidate, Ketamine, Emergency Endotracheal Intubation
- Where
- United States
- Volunteers
- 801 people
- Sponsor
- University of Texas Southwestern Medical Center
Delirium, Agitation
Effects of Dexmedetomidine on Delirium Duration of Non-intubated ICU Patients (4D Trial)
The primary purpose of the study is to evaluate whether dexmedetomidine is effective in treating agitated delirium of non-intubated ICI patients
- Trial name
- 4D (NCT03317067)
- Testing
- Dexmedetomidine
- Where
- France
- Volunteers
- 168 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hypoxia
Apneic Oxygenation During Airway Management in Pediatric Patients
Airway placement after anesthetic induction in pediatric patients is routinely performed at our institution without apneic oxygenation.
- Trial name
- NCT02437864
- Testing
- Supplemental oxygen via nasal cannula
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of New Mexico
Airway Control, Anesthesia
Ketamine Versus Etomidate for Rapid Sequence Intubation
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Trial name
- NCT01823328
- Testing
- Ketamine, Etomidate
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Hennepin Healthcare Research Institute
Eosinophilic Esophagitis
Comparing Anesthetic Techniques in Children Having Esophagogastroduodenoscopies
The purpose of this research study is to compare the safety and effectiveness of three commonly used techniques for delivering anesthesia during a procedure known as esophagogastroduodenoscopy.
- Trial name
- NCT02038894
- Testing
- Intubated with Sevoflurane (IS), Intubated with Propofol (IP), Zofran - no intubation
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Critical Illness
Ketamine / Propofol Admixture "Ketofol" at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial
The hypothesis of this study is that a Ketamine / Propofol mixture will produce more stable hemodynamics as compared to Etomidate during emergent intubations in the intensive care unit.
- Trial name
- KEEP PACE (NCT02105415)
- Testing
- Ketamine / Propofol Admixture, Etomidate
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Mayo Clinic
Child
Correlation of Nasopharyngeal (NP) and Lower Oesophageal (LO) Temperatures in Ventilated Children
Children lose heat under general anaesthesia, thus temperature is routinely monitored during anaesthesia for all but the shortest cases, and active warming can be used to prevent hypothermia and its resulting complications.
- Trial name
- NCT02201628
- Testing
- Nasopharyngeal and oesophageal temperature probes
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Alzheimer Disease, Dementia
Pragmatic Trial of Video Education in Nursing Homes
This is a pragmatic cluster-randomized control trial (RCT) of an Advance Care Planning (ACP) Video Program for nursing home (NH) patients ≥ 65 years old who are cared for in 360 NH facilities (intervention arm n=119; control arm…
- Conditions
- Alzheimer Disease, Dementia, Heart Failure, Pulmonary Disease, Chronic Obstructive
- Trial name
- PROVEN (NCT02612688)
- Testing
- ACP Video Program
- Where
- 2 sites in United States
- Volunteers
- 197,692 people
- Sponsor
- Brown University
Sepsis, Trauma
The Effect of Etomidate on Patient Outcomes After Single Bolus Doses
The primary aim is to determine the difference in hospital length of stay between septic patients given etomidate and those given midazolam for induction during rapid sequence intubation (RSI) in the emergency department.
- Trial name
- NCT00441792
- Testing
- Etomidate, midazolam
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Advocate Hospital System
COVID-19, Cytokine Storm
Fluoxetine to Reduce Intubation and Death After COVID19 Infection
This project will test the efficacy of fluoxetine to prevent serious consequences of COVID-19 infection, especially death. Becoming sick with COVID-19 virus or any other serious respiratory condition is not fun.
- Trial name
- NCT04377308
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toledo Health Science Campus
Inguinal Hernia, Inguinal Hernia, Indirect
Laryngeal Mask Airway in Laparoscopic Hernia Repair
This prospective randomized study will evaluate the effectiveness of laryngeal mask airway (LMA) versus endotracheal intubation (ETT) for patients undergoing laparoscopic inguinal hernia at CMH.
- Conditions
- Inguinal Hernia, Inguinal Hernia, Indirect, Inguinal Hernia Bilateral, Inguinal Hernia Unilateral
- Trial name
- NCT06023394
- Testing
- Laryngeal Mask Airway, Endotracheal Tube Device
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Children's Mercy Hospital Kansas City