Clinical trials: Investigation Time
Ovarian Cancer, Fallopian Tube Cancer
Using Genetic Profile to Determine the Treatment for Patients With Ovarian Cancer Who Previously Received a PARP-inhibitor
The purpose of this research study is to see how useful it is to look at biomarkers in the blood and tumor tissue of participants with ovarian, fallopian tube or primary peritoneal cancer who have previously received treatment…
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, High Grade Serous Cancer
- Trial name
- NCT05065021
- Testing
- Niraparib, Dostarlimab, Bevacizumab
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Operation Site Bleed
Evaluation of an Absorbable Surgical Hemostatic Agent: Thrombi-Gel® Versus Gelfoam-Thrombin
This trial is designed as a prospective, multi-center, randomized, feasibility clinical trial to evaluate the safety and efficacy of Thrombi-Gel as an absorbable surgical hemostat.
- Trial name
- Control (NCT00652314)
- Testing
- Thrombi-Gel
- Where
- 7 sites in United States
- Volunteers
- 97 people
- Sponsor
- Vascular Solutions LLC
Allergic Conjunctivitis
Evaluation of Efficacy of Ophthalmic Solution in Induced Acute Allergic Conjunctivitis
The purpose of this study is to establish the efficacy of R89674 0.25% ophthalmic solution compared with placebo in alleviating the signs and symptoms of conjunctival allergen challenge-induced allergic conjunctivitis
- Trial name
- NCT00241319
- Testing
- R89674 (generic name not yet established)
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Vistakon Pharmaceuticals
Pressure Injury, Risk Assessment
Positioning Duration and Pressure Injury Risk
This research aims to investigate the effect of positioning times on the risk of pressure injury in critically ill patients.
- Trial name
- PIP-ICU (NCT07355439)
- Testing
- Position Change - 1 Hour, Position Change - 2 Hours
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- SEMA ŞAHİNER
Right-handed Healthy Adults
The Investigation of Acute Effects of Action Observation Training on Upper Extremity Functionality, Reaction Time and Cognitive Functions in Right-handed Healthy Subjects
The aim of the study is to investigate the acute effects of action observation training on upper extremity functionality, reaction times, and cognitive functions in right-handed healthy subjects.
- Trial name
- NCT04932057
- Testing
- Action observation Training, Action Practice, Observation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Celiac Disease, Coeliac Disease
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GSK3915393 in Healthy Participants and to Evaluate the Interaction Between GSK3915393 and Grapefruit Juice and Itraconazole
This is a 3-part first time into human study (FTIH) study for GSK3915393. Parts A and B of the study will evaluate the safety, tolerability and pharmacokinetics (PK) of single ascending and repeat oral doses of GSK3915393 in…
- Trial name
- NCT04604795
- Testing
- GSK3915393 Capsules, GSK3915393 Solution for Infusion, Itraconazole
- Where
- United Kingdom
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Neonatal Resuscitation, Heart Rate Assessment
Impact of a Mobile Application for Heart Rate Assessment in Simulated Neonatal Resuscitation
NeoTapAdvancedSupport (NeoTapAS) is a free-of-charge mobile application that showed good accuracy in HR estimation. This study aims to evaluate the impact of NeoTapAS on timing of HR communication and of resuscitation…
- Trial name
- NCT03730025
- Testing
- Auscultation plus NeoTapAS, Auscultation without NeoTapAS
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Dyslipidemia
Evaluation of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TA-8995 With Single, Escalating Doses in Healthy Subjects
The purpose of this study is to assess the safety and tolerability of single doses of TA-8995 in healthy Caucasian and Japanese volunteers.
- Trial name
- NCT01878474
- Testing
- TA-8995
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Tanabe Pharma Corporation
Prostatic Neoplasms
Evaluation of Different Methods of Ultrasound Image Analysis for Real-time Monitoring of HIFU Prostate Cancer Treatment
The ELASTO-US study is a single center feasibility study to evaluate 3 methods of analyzing real-time ultrasound images acquired during High Intensity Focused Ultrasound (HIFU) treatment in patients with localized prostate…
- Trial name
- ELASTO-US (NCT05714774)
- Testing
- HIFU treatment of prostate cancer
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Heart Failure
A First Time in Human (FTIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GSK3884464 in Healthy Participants
This will be a FTIH study which aims to evaluate safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single and repeat oral doses of GSK3884464 administered to healthy participants.
- Trial name
- NCT05044325
- Testing
- GSK3884464
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Patients With Pharmaceutical Record
Medication Assessment Through Real Time Information eXchange - Distributed Pharmaceutical Record System
The aim of MATRIX-DPRS is to assess the clinical and organizational impacts of the use of the medication record, opened, filled and managed by pharmacists (from private office and hospital units) by hospital physicians in private…
- Trial name
- MATRIX-DPRS (NCT03076853)
- Testing
- Opening of the Pharmaceutical Record
- Where
- France
- Volunteers
- 511 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Heart Failure, Diastolic
Exercise Pulmonary Transit Time
The study seeks to measure pulmonary transit time via contrast-echocardiography before and after exercise.
- Trial name
- NCT04336995
- Testing
- contrast echocardiography
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Spinal Cord Neoplasm
FDG PET-MRI for the Diagnosis of Spinal Cord Lesions
To compare the results and understand the possible benefits from FDG-PET/MRI during different scanning time points after FDG, a type of contrast drug, is given.
- Trial name
- NCT04219969
- Testing
- Fludeoxyglucose F-18, Magnetic Resonance Imaging, Positron Emission Tomography
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- M.D. Anderson Cancer Center
Kidney Failure, Chronic
Observational Study to Evaluate the Time to Achieving the Maintenance Dose of Zemplar® (Paricalcitol Injection) in the Treatment of Patients Suffering From End-stage Renal Disease and Severe Over-reactivity of the Parathyroid Glands
This observational study will evaluate the clinical benefit of Zemplar (paricalcitol injection) in daily routine practice in end-stage renal disease patients with severe over-reactivity of parathyroid glands.
- Trial name
- NCT01273597
- Where
- 11 sites in Hungary
- Volunteers
- 60 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Breast Neoplasms, Quality of Life
Assessment of Quality of Life and Treatment Times for Patients With Invasive Type Breast Cancer in Martinique
Cancer and its treatments can be factors that alter the quality of life of patients. The induced alteration of the quality of life can influence compliance and impact survival.
- Conditions
- Breast Neoplasms, Quality of Life, Survivorship
- Trial name
- Qualibreast-MQ (NCT04918082)
- Testing
- Quality of life questionnaires
- Where
- Martinique
- Volunteers
- 133 people
- Sponsor
- University Hospital Center of Martinique
Type 1 Diabetes Mellitus With Diabetic Gastroparesis, HbA1c
Safety and Efficacy of Insulin Degludec/Insulin Aspart in Patients With T1DM
In this prospective, randomized, open-label, parallel group trial, the safety and efficacy of insulin degludec/insulin aspart (IDegAsp) twice daily will be compared with basal insulin once or twice daily plus pre-prandial insulin…
- Conditions
- Type 1 Diabetes Mellitus With Diabetic Gastroparesis, HbA1c, Time in Range
- Trial name
- NCT04965051
- Testing
- insulin degludec/insulin aspart (IDegAsp), basal insulin plus pre-prandial insulin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Artery Disease
Phase 3 Safety and Imaging Study of AI-700 in Patients With Suspected Coronary Artery Disease Undergoing Coronary Angiography
This study was designed to evaluate the ability of AI-700-enhanced rest-stress echocardiography to detect coronary artery disease (CAD) in patients with suspected ischemic heart disease who are indicated for coronary angiography.
- Trial name
- NCT00156845
- Testing
- AI-700 contrast-enhanced echocardiography
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Acusphere
Breast Cancer
The Value of Time-Dependent Diffusion MRI and Magnetic Resonance Elastography in the Precise Diagnosis and Efficacy Assessment of Breast Cancer
We consecutively enrolled patients presenting with breast space-occupying lesions at our hospital. Medical imaging data from simultaneously acquired ultrafast DCE-MRI, time-dependent diffusion MRI (TDD-MRI), magnetic resonance…
- Trial name
- NCT07608081
- Testing
- The Value of Time-Dependent Diffusion MRI and Magnetic Resonance Elastography in the Precise Diagnosis and Efficacy Assessment of Breast Cancer
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Yunnan Cancer Hospital
Hemophilia A
BAY79-4980 Compared to rFVIII-FS in Previously Treated Patients With Severe Hemophilia A
A study to assess treatment with a new formulation of recombinant factor VIII reconstituted with liposomes (BAY79-4980) to evaluate whether a once-a-week treatment is safe and can prevent bleeds in subjects with severe…
- Trial name
- NCT00623727
- Testing
- rFVIII-FS/pegylated liposomes (BAY79-4980), rFVIII-FS/WFI (BAY14-2222)
- Where
- 95 sites in United States, Argentina and 24 more
- Volunteers
- 143 people
- Sponsor
- Bayer
Cervical Dystonia
Zinc as an Adjunctive Therapy for Cervical Dystonia
The goal of this clinical trial is to evaluate if supplemental zinc can prolong the duration of benefit of botulinum toxin injections in cervical dystonia patients receiving care at the University of Florida.
- Trial name
- NCT07140874
- Testing
- Zinc citrate
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
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