Clinical trials: Investigation Time
Type 1 Diabetes
Tandem Control-IQ Evaluation Regarding Glucose Metrics, Sleep, and Health Economics
To evaluate Tandem Control-IQ compared with rtCGM and insulin pen respectively rtCGM and insulin pump treatment in children and adolescents regarding glucose control, sleep and health economics for 18 months.
- Trial name
- STARCARE (NCT05969106)
- Testing
- Tandem Control-IQ
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Vastra Gotaland Region
Abdominal Aortic Aneurysm, Endoleak
AneuFix - Prophylactic Sac Filling
This study is set up to assess the feasibility and safety of the clinical procedure using AneuFix in a prophylactic setting at the time of EVAR endograft implantation.
- Trial name
- NCT04307992
- Testing
- Prophylactic sac filling with AneuFix
- Where
- 3 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- TripleMed B.V.
Maxillary Hypoplasia, Cleft Lip Palate
Time and Type Dependent Evaluation of Different Techniques for Correction of Cleft Maxillary Hypoplasia
Maxillary hypoplasia in CLP deformities results from congenital reduction in midfacial growth and the effects of the surgical scar from CLP repair.Turvey et al.
- Conditions
- Maxillary Hypoplasia, Cleft Lip Palate, Orthognathic Surgery
- Trial name
- NCT06852196
- Testing
- orthognathic surgery ,lefort 1,bsso ,DO, distraction osteogenesis
- Volunteers
- 22 people
- Sponsor
- Assiut University
Migraine
A Study Evaluating the Effectiveness of PEA Compared to Placebo for Reducing Pain Severity and Duration of Migraines.
This is a double-blind randomised controlled study to evaluate the effectiveness of orally-dosed Palmitoylethanolamide (PEA) compared to placebo for reducing pain severity and duration of migraines in otherwise healthy…
- Trial name
- NCT05046522
- Testing
- Palmitoylethanolamide sold as Levagen +
- Where
- Australia
- Volunteers
- 80 people
- Sponsor
- RDC Clinical Pty Ltd
Intubation, Thoracic Surgery
Evaluation of the EZ Blocker
In anesthetized patients the airway needs to be secured due to lack of protective reflexes. Golden standard is the endotracheal intubation. In patients undergoing lung surgery single lung ventilation is essential.
- Conditions
- Intubation, Thoracic Surgery, One-lung Ventilation
- Trial name
- NCT01171560
- Testing
- endotracheal intubation
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Chronic Hepatitis B, Chronic Hepatitis C
Assessment of Liver FIBROsis by Real-time Tissue ELASTography in Chronic Liver Disease
This is a multi-center cross-sectional study in which the Real-time Tissue Elastography® measurements will be collected prospectively from patients with chronic hepatitis B or C virus presenting for liver biopsy.
- Trial name
- FIBROELAST (NCT01360879)
- Where
- Japan
- Volunteers
- 500 people
- Sponsor
- Kindai University
Time of the Crowning of the Fetal Head, Levator Ani Avulsion
The Effect of Crowning Time on Levator Ani Muscle Avulsion
Levator ani muscle is one of the main components of perineal muscles and plays a crucial role in urinary continence and pelvic organ support.
- Conditions
- Time of the Crowning of the Fetal Head, Levator Ani Avulsion, Labor Delivery, Postpartum
- Trial name
- NCT07210788
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Pulmonary Tuberculosis
Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis
This multicenter, two-stage, open-label, randomized trial will aim to assess the efficacy, safety, optimal duration, and pharmacokinetics (PK) of Delamanid, Bedaquiline, OPC-167832, and Sutezolid (DBOS) and Pretomanid…
- Trial name
- NCT05971602
- Testing
- Delamanid, Bedaquiline, OPC-167832, and Sutezolid (DBOS), Pretomanid, Bedaquiline, OPC-167832, and Sutezolid (PBOS), Isoniazid, Rifampicin, Pyrazinamide, Ethambutol (HRZE)
- Where
- 13 sites in Philippines, South Africa
- Volunteers
- 93 people
- Sponsor
- Gates Medical Research Institute
Mitral Valve Prolapse, Myxomatous Mitral Valve Degeneration
AI-Based Shape and Function Analysis of Mitral Valve Prolapse Using 3D Ultrasound
This study aims to develop and validate a fully automated imaging and modeling pipeline for the analysis of mitral valve prolapse (MVP) using real-time three-dimensional transesophageal echocardiography (RT3DE).
- Trial name
- AI4MVP (NCT07384871)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS Policlinico S. Donato
Diphtheria, Tetanus
Study of the Effect of Pneumococcal Conjugate Vaccine (PCV) on Immunogenicity of Pentacel™
This study is designed to evaluate in a controlled manner the effect of Prevnar® on the immune responses of Pentacel™ Primary Objective - Stage I: To compare the immune responses elicited by an infant series of Pentacel™ when…
- Conditions
- Diphtheria, Tetanus, Haemophilus Infection, Pertussis
- Trial name
- NCT00772928
- Testing
- Pentacel™: HCPDT-IPV//PRP-T Vaccine and Prevnar®
- Where
- 23 sites in United States
- Volunteers
- 1,167 people, healthy volunteers welcome
- Sponsor
- Sanofi
Diabetes Mellitus, Type 1
Monotherapy With Rapamycin in Long-standing Type 1 Diabetes
This study is a phase 2, single-center, prospective, randomized, double-blind, placebo-controlled, 3-arm parallel group (1:1:1) intervention trial to determine the efficacy of 4 weeks rapamycin treatment and 4 weeks rapamycin…
- Trial name
- MONORAPA (NCT02803892)
- Testing
- rapamycin, Vildagliptin
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- Piemonti Lorenzo
Burns
Oleogel-S10 Versus Standard of Care in Healing of Grade 2a Burn Wounds
The main goal of this phase III clinical trial is to show safety and efficacy of Oleogel-S10 in the acceleration of wound healing of grade 2a burn wounds.
- Trial name
- NCT01657292
- Testing
- Oleogel-S10 ointment, Octenilin® wound gel
- Where
- 9 sites in Germany, Sweden and 2 more
- Volunteers
- 61 people
- Sponsor
- Birken AG
Multiple Myeloma, Bone Metastases
Evaluation of Whole Body Examination by MRI Integrating the "Zero Time Eco" Sequence (ZTE, Pseudo-CT) for the Detection of Bone Lesions in Multiple Myeloma: Comparison With Pet / CT and Whole Body Scanner
To assess the added value of magnetic resonance imaging (MRI) of the skeleton compared to other validated techniques for the detection of bone lesions in patients with multiple myeloma.
- Trial name
- MM-ZTE (NCT05381077)
- Testing
- MRI
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Healthy
Pilot Study to Evaluate the Duration of Effects on Simulated Car Driving and Cognitive Performance After a Single Dose of JNJ-42847922, Zolpidem and Placebo in Healthy Participants
The purpose of the study is to evaluate the effects of JNJ-42847922, compared to zolpidem and placebo, on driving performance as assessed by the mean difference of standard deviation of lateral position (SDLP) after forced…
- Trial name
- NCT02578472
- Testing
- JNJ-42847922, Zolpidem
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Janssen-Cilag International NV
Healthy Male Volunteers
First-time-in-man, to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BP1.5375
Phase I Single Ascending Dose (Part 1), phase IIa Proof Of Concept (Part 2)
- Trial name
- NCT01965301
- Testing
- BP1.5375 suspension, Diphenhydramine
- Where
- Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bioprojet
Critical Illness, Metabolism Disorders
Development of a Novel Algorithm for Real-Time Bedside Assessment of Insulin Resistance in Critically Ill Patients Based on Continuous Glucose Monitoring Data
This study aims to develop and validate a novel algorithm for the real-time assessment of insulin resistance in critically ill patients using Continuous Glucose Monitoring (CGM).
- Conditions
- Critical Illness, Metabolism Disorders, Insulin Resistance
- Trial name
- NCT07385391
- Where
- China
- Volunteers
- 179 people
- Sponsor
- Chinese Medical Association
Sudden Cardiac Death, Sudden Cardiac Arrest
Time and Dose Evaluation of Stearidonic Acid (SDA) to Eicosapentaenoic Acid (EPA) in Red Blood Cells
The purpose of this study is to assess the relationships between dose and time of consumption of stearidonic acid (SDA) and eicosapentaenoic acid (EPA) on EPA enrichment of red blood cell (RBC) membranes in men and women.
- Conditions
- Sudden Cardiac Death, Sudden Cardiac Arrest, Cardiovascular Disease
- Trial name
- NK (NCT01038440)
- Testing
- Safflower Oil, EPA, SDA
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Solae, LLC
Childhood Obesity
Efficacy Evaluation of a Mixed Compound of Antioxidants in Terms of Endothelium Damage/Function in Pediatric Subjects With Obesity.
The aim of our study was to test the effects on endothelium of a combination of curcumin, resveratrol, plus zinc, magnesium, selenium and Vitamin D in a cohort of pediatric subjects with obesity.
- Trial name
- OBELIX (NCT04723849)
- Testing
- Auxilie® Immuplus, Envicon Medical, Verona, Italy
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Universita di Verona
Peripheral Vascular Disease, Intermittent Claudication
Evaluation of Cilostazol in Combination With L-Carnitine
The purpose of this study is to see how safe and effective L carnitine taken with cilostazol is compared to placebo taken with cilostazol for people with intermittent claudication.
- Conditions
- Peripheral Vascular Disease, Intermittent Claudication, Peripheral Arterial Disease
- Trial name
- ECLECTIC (NCT00822172)
- Testing
- Levocarnitine tartrate, cilostazol
- Where
- 24 sites in United States
- Volunteers
- 164 people
- Sponsor
- Colorado Prevention Center
Edentulous Jaw
Occlusion and Disocclusion Time in Immediately Loaded Overdentures Supported by Two Splinted Versus Non Splinted Interforaminal Implants
complete denture wearers struggle to eat well with their dentures due to poor denture retention, stability, and occlusal disharmony.
- Trial name
- NCT06376019
- Testing
- solitary Implant loading with ball attachment, splinted Implant loading with intra oral welding, complete denture
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
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