Clinical trials: Investigation Time
Alzheimer's Disease
Evaluation of PET Scan Timing Relative to AV-45 Injection Time
This study will re-read 10-minute positron emission tomography (PET) scans acquired in previous clinical studies of AV-45 at 30 and 50 minutes after injection and compare the results.
- Trial name
- NCT01565356
- Testing
- florbetapir F 18
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Avid Radiopharmaceuticals
Hepatitis B
Adolescents' Response to Hepatitis B Vaccine Booster Dose
The aims of this study are to determine: 1. the degree of immunity against hepatitis B, 2. factors associated with immunity against hepatitis B, 3.
- Trial name
- REACH (NCT01341275)
- Testing
- hepatitis B vaccine
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Baylor College of Medicine
Urothelial Carcinoma
Cystoscopic Evaluation Predicting pT0 Urothelial Carcinoma of the Bladder
A prospective, investigational study to assess the accuracy of standardized cystoscopic evaluation with tissue sampling performed immediately prior to definitive radical cystectomy to predict pathologic tumor stage and identify…
- Trial name
- NCT02968732
- Testing
- Radical Cystectomy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Fox Chase Cancer Center
Out-Of-Hospital Cardiac Arrest After Initial Successful Resuscitation, Out of Hospital Cardiac Arrest
RESTORE-ZG: Return of Effective Spontaneous Circulation Resuscitation Evaluation Canton of Zug
This study looked at cardiac arrest that happens outside a hospital. Cardiac arrest means the heart suddenly stops pumping blood. When this happens, a person collapses and needs help right away.
- Conditions
- Out-Of-Hospital Cardiac Arrest After Initial Successful Resuscitation, Out of Hospital Cardiac Arrest, Out of Hospital Setting, Defibrillation
- Trial name
- RESTORE-ZG (NCT07750119)
- Testing
- Prehospital resuscitation care
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Felix Brinkmann
Rectal Cancer, Total Mesorectal Excision
Timing Evaluation of Stoma Closure (TIMES). Early vs Late Closure of Stoma After Rectal Cancer Surgery.
The purpose of this study is to asses the safety and efficacy of early stoma closure (2-3 weeks after total mesorectal excision) vs late closure (16-24 weeks after mesorectal excision).
- Conditions
- Rectal Cancer, Total Mesorectal Excision, Ileostomy - Stoma, Ileostomy; Complications
- Trial name
- TIMES (NCT05284864)
- Testing
- Stoma closure
- Where
- 9 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario La Fe
ESCAPE Intervention+NRT, quitSTART Intervention+NRT
Enhancing Smoking Cessation for African American People Everywhere
The present study aims to investigate the efficacy of an mHealth smoking cessation and HIV disease management intervention among a nationally representative sample of African America/Black (hereafter refer to as Black) persons…
- Conditions
- ESCAPE Intervention+NRT, quitSTART Intervention+NRT, CTRL+NRT
- Trial name
- ESCAPE (NCT07024992)
- Testing
- ESCAPE app + NRT, quiSTART app + NRT, Control (CTRL)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Houston
Infantile Respiratory Distress Syndrome, Ventilator Lung; Newborn
Automatic Oxygen Control (SPOC) in Preterm Infants
Single-center, randomised controlled, cross-over clinical trial in preterm infants born at gestational age below 34+1/7 weeks receiving supplemental oxygen and respiratory support (continous positive airway pressure (CPAP) or…
- Trial name
- optimalSPOC (NCT03785899)
- Testing
- SPOCnew, 8s SpO2 averaging, SPOCold
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University Hospital Tuebingen
Core Stability, Core Stabilization
Investigation of the Relationship Between Core Stability and Reaction Time, Hand-Eye Coordination, Pain, and Functional Status in Individuals With Rotator Cuff Lesions
Rotator cuff lesions are among the most common problems within musculoskeletal disorders. The prevalence of these lesions increases with age, and they encompass a wide spectrum of various injuries and pathological conditions.
- Conditions
- Core Stability, Core Stabilization, Reaction Time, Pain
- Trial name
- NCT07089628
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Diverticulitis, Colonic, Acute Disease
Study to Evaluate the Duration of Treatment With Ertapenem in Acute Attacks of Sigmoid Diverticulitis
The purpose of this study is to compare the efficacy (by assessing the clinical success of treatment) of intravenous antibiotic therapy with ertapenem in patients with acute attacks of sigmoid diverticulitis for 4 vs. 7 days.
- Trial name
- NCT00097734
- Testing
- ertapenem
- Where
- Germany
- Volunteers
- 540 people
- Sponsor
- Klinikum Hanover-Siloah Hospital
Migraine
OnaBotulinumtoxin-A in Chronic Migraine Patients With Short or Long Disease History (the BACH Study)
The goal of this observational prospective multicentric study, 12 months duration is to investigate whether the history of Chronic Migraine and, more precisely, its duration for over or less than 10 years, can predict OBT-A…
- Trial name
- BACH (NCT06537700)
- Testing
- OnabotulinumtoxinA OBT-A
- Where
- 6 sites in Italy
- Volunteers
- 115 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Acute Apical Abscess
Antibacterial Effects of Intracanal Medicaments in Acute Apical Abscesses
This randomized clinical trial compares the antibacterial effects of calcium hydroxide and a calcium silicate-based intracanal medicament in teeth with acute apical abscesses.
- Trial name
- CAM-AAA (NCT07819240)
- Testing
- Calcium Hydroxide Intracanal Medicament, Calcium Silicate-Based Intracanal Medicament
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ataturk University
Schizophrenia
First Time in Human Study With GSK1018921
GSK1018921 is a new drug under development for the treatment of schizophrenia. GSK1018921 differs from other available drugs in its mode of action and it is assumed that it may have an effect in the treatment of so-called…
- Trial name
- NCT00527020
- Testing
- GSK1018921, Nicotine Lozenges
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Supportive Care, Cancer
Feasibility Study of the Advanced Symptom Management System (ASyMS) in Canadian Cancer Patients
The Advanced Symptom Monitoring and Management System - Canada (ASyMS-Can) is a remote phone-based symptom management system that prompts patient self-care and clinician telephone triage and intervention based on alerts for…
- Trial name
- ASyMS-Can (NCT03335189)
- Testing
- ASyMS-Can
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University Health Network, Toronto
Barrett's Esophagus
Confocal Laser Probe to Treat Barrett's Esophagus
The purpose of this study is to further validate the use of probe-based confocal laser endomicroscopy (pCLE) for the evaluation of Barrett's Esophagus and associated neoplasia in a larger patient base.
- Trial name
- pCLE (NCT02852525)
- Testing
- Confocal laser endomicroscopy (pCLE)
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Virendra Joshi
Cancer
Phase I Study to Assess the Safety, Pharmacokinetics, & Pharmacodynamics of GSK923295 in Subjects w/ Refractory Cancer
This is a Phase I, open-label, first time in human study of GSK923295, in adult subjects with cancers that do not respond to standard therapy.
- Trial name
- NCT00504790
- Testing
- GSK923295
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- GlaxoSmithKline
Myocardial Infarction, Acute Coronary Syndromes
Shortened Aggrastat® Versus Integrilin in Percutaneous Coronary Intervention
The purpose this study is to assess whether a tirofiban regimen of a high-dose bolus plus a shortened infusion duration compared to label-dosing eptifibatide in patients undergoing percutaneous coronary intervention (PCI) is…
- Conditions
- Myocardial Infarction, Acute Coronary Syndromes, Unstable Angina
- Trial name
- SAVI-PCI (NCT01522417)
- Testing
- Short Tirofiban, Eptifibatide, Long Tirofiban
- Where
- 13 sites in United States
- Volunteers
- 535 people
- Sponsor
- Medicure
Mechanical Failure of Dental Implant Nos
Clinical Efficacy of Nobel Parallel CC Implants With on1 Abutment in Posterior Area Participants
1. Research background NobelBiocare manufacture put forward a new abutment called on1. This concept is based on a two-stage abutment in which the on1 abutment is placed directly on the implant during surgery and will not be…
- Trial name
- NCT05399589
- Testing
- use on1 abutment instead of healing cap in test group, use healing cap in control group
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Allergic Conjunctivitis
Evaluation of the Safety and Pharmacokinetics of Brimonidine Tartrate 0.025%/Ketotifen Fumarate 0.035% Combination Ophthalmic Solution
To compare the safety and tolerability of brimonidine tartrate 0.025%/ketotifen fumarate 0.035% combination ophthalmic solution versus its vehicle in healthy adult subjects and in pediatric subjects.
- Trial name
- NCT05815758
- Testing
- Brimonidine Tartrate 0.025%/Ketotifen Fumarate 0.035% Ophthalmic Solution (Combo), Vehicle of brimonidine tartrate 0.025%/ketotifen fumarate 0.035% ophthalmic solution
- Where
- 7 sites in United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Diabetes Mellitus
Assessment of HGI (Hemoglobin Glycation Index) Variability Over Time in Patients Living With Diabetes Using Continuous Glucose Monitoring ( GAP OUEST )
The goal of this clinical trial is to learn about the variability of HGI (Hemoglobin Glycation Index) over time in patients living with diabetes using a continuous glucose monitoring.
- Trial name
- GAP OUEST (NCT06185491)
- Testing
- HGI
- Where
- 9 sites in France
- Volunteers
- 750 people
- Sponsor
- Nantes University Hospital
Non Small Cell Lung Cancer, 4D CT
An Outcome Analysis for Stereotactic Body Radiation Therapy (SBRT) Treatment of Non-Small Lung Cancer Patients Using 4D PET/CT With Real-Time Position Management (RPM™) System and a Concomitant Evaluation of the Impact and Performance Characteristics of the Immobilization System
The goals of this clinical research are to evaluate the outcomes and tumor response for early stage non-small lung cancer (NSCLC) patients undergoing Stereotactic Body Radiation Therapy (SBRT) using four dimensional (4D) Positron…
- Trial name
- NCT02067858
- Testing
- Stereotactic Radiosurgery
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Steven Burton
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