Clinical trials: Investigation Time
Patent Ductus Arteriosus
Paracetamol Treatment of the Borderline Significant PDA
The therapeutic approach to the patent ductus arteriosus (PDA) in the premature neonate remains controversial. Currently it is generally accepted to treat only hemodynamically significant PDAs.
- Trial name
- NCT02819414
- Testing
- Paracetamol drops
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Shaare Zedek Medical Center
Hepatocellular Carcinoma
68 Ga PSMA PET/MRI for Hepatocellular Carcinoma
This is a pilot study to investigate the evaluate to use of a drug/radiopharmaceutical called Gallium-68 PSMA-11 (68Ga-PSMA-11) for use in PET/MRI evaluation of hepatocellular carcinoma
- Trial name
- NCT03982407
- Testing
- 68Ga-PSMA-11 PET/MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Ajit H. Goenka, MD
Bariatric Surgery
Lexion AP 50/30 Warmed Humidified Real Time CO2 Insufflation vs Airseal Recirculated CO2/Air Insufflation in Minimally Invasive Bariatric (Gastric Bypass) Surgery
The purpose of this study is to To determine the effect of warm and humidified (WH) carbon dioxide (CO2) on post-operative pain/analgesia requirement in patients undergoing laparoscopic bariatric surgery.
- Trial name
- NCT05838300
- Testing
- Warm humidified CO2, Dry CO2
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- The University of Texas Health Science Center, Houston
Kidney Neoplasms
Assessment of Oncological and Functional Outcomes After Robot Assisted Partial Nephrectomy Versus Laparoscopic Partial Nephrectomy
Currently, partial nephrectomy (PN) is considered as the gold standard treatment modality for small renal masses. In this setting, robot-assisted and conventional laparoscopic approaches are gaining more consensus every day.
- Trial name
- NCT02924922
- Testing
- Laparoscopic partial nephrectomy, Robot assisted partial nephrectomy, Conventional laparoscopic instruments
- Where
- Switzerland
- Volunteers
- 85 people
- Sponsor
- Luzerner Kantonsspital
Diabetes Type 2
Evaluation of Block Duration in Type 2 Diabetes Patients
Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after…
- Trial name
- Diabeteblock (NCT01704612)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pierre and Marie Curie University
Leg Injury
Evaluation of Improved Preparation Time to a Coverage in Patients With Acute Wounds by Use of VistaCare® Versus Dressings
Primary objective: Demonstrate that in patients with acute leg wounds with skin defect, VistaCare® accelerates the formation of a quality granulation tissue and reduces preparation time to a cover gesture.
- Trial name
- VISTACARE01 (NCT02963519)
- Testing
- VistaCare®, Dressings
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Qualissima
End Stage Renal Disease
Pharmacokinetics and Optimal Dose of Ertapenem in Hemodialysis Patients
The purpose of this study is to determine the amount of ertapenem in the blood over time between hemodialysis session.
- Trial name
- NCT02159859
- Testing
- Ertapenem
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Corewell Health East
Atrial Fibrillation, Abnormal Heart Rhythms
COMparison of Physiological Algorithms for Real-time Evaluation of Atrial Fibrillation
This is a cohort study to evaluate algorithms for mapping atrial fibrillation by mapping atrial structure and mapping electrical activity to detect physiologically important areas.
- Trial name
- COMPARE_AF (NCT02997254)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Stanford University
Brain Injuries, Multiple Sclerosis
Evaluation of an Acceptance and Commitment Therapy Group for Adjustment Difficulties in Neurological Conditions
With an increase of over 38% in neurological related hospital admissions between 2008-13, there are now over 12.5 million cases of individuals with neurological conditions in the UK.
- Conditions
- Brain Injuries, Multiple Sclerosis, Parkinson Disease, Stroke
- Trial name
- NCT02454465
- Testing
- Acceptance and Commitment Therapy group
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Hertfordshire
Leishmaniasis
Safety, Tolerability and Pharmacokinetics (PK) Investigation of GSK3494245 in Healthy Participants
This study is the first to test GSK3494245 in humans, to evaluate its safety, tolerability, and pharmacokinetics (PK) after a single dose.
- Trial name
- NCT04504435
- Testing
- GSK3494245
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 2
Evaluation of the Effect on Glucose Control and Safety of AC2993 in Patients With Type 2 Diabetes Treated With Metformin, Sulfonylurea, or Metformin and Sulfonylurea Combination
This multi-center, open-label study is designed to examine the effects on long-term glucose control and safety of AC2993 in patients with type 2 diabetes treated with metformin, sulfonylurea, or metformin and sulfonylurea…
- Trial name
- NCT00044668
- Testing
- AC2993
- Where
- 3 sites in Hungary
- Volunteers
- 155 people
- Sponsor
- AstraZeneca
Diabetic Foot, Varicose Ulcer
Study Comparing VERSAJET With Conventional Surgical Procedures in the Removal of Unhealthy Tissue From Lower Limb Ulcers
The purpose of this study is to compare the VERSAJET™ device with conventional surgical procedures (performed with a scalpel) in the debridement (removal of unhealthy tissue) of lower limb ulcers.
- Conditions
- Diabetic Foot, Varicose Ulcer, Pressure Ulcer
- Trial name
- NCT00521027
- Testing
- Versajet Hydrosurgery System, Conventional surgical debridement techniques
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Smith & Nephew, Inc.
Development of LIFU for Clinical Purposes
Investigation of the Duration of Low-intensity Focused Ultrasound
This project examines the effects of various durations of noninvasive neuromodulation on muscle contractions. The investigators believe this study will help to better understand noninvasive brain stimulation techniques that may…
- Trial name
- NCT05147103
- Testing
- Low-Intensity Focused Ultrasound
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Coronary Angiography, Coronary Artery Disease
Assessment Of Total Coronary Circulation Time Using TIMI Frame Count Method (TCCT-TIMI)
The aim of this study is to evaluate and describe the total coronary circulation time (TCCT) by using TIMI frame count method in patients performed coronary angiography.
- Conditions
- Coronary Angiography, Coronary Artery Disease, Coronary Artery Ectasia, Slow-Flow Phenomenon
- Trial name
- TCCT-TIMI (NCT02818127)
- Testing
- coronary angiography
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Vascular and Molecular Cardiology Society
Analgesia
Assessment of the Effect of Age on Duration of Analgesia From Single-shot Femoral Nerve Blocks
Cohort study to examine the effect of age on duration of analgesia in patients receiving single-shot femoral nerve block prior to surgery, by postoperative phone follow-up questionnaire.
- Trial name
- NCT04495413
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Infection
PCT and Clinical Algorithm for Determination of Duration of Antibiotics
Patients in the ICU whose infection is resolving will be randomized to standard duration of antibiotics compared to duration determined by a combination of a procalcitonin value and a simple evaluation of clinical status.
- Trial name
- NCT01572831
- Testing
- PCT and clinical algorithm for stopping abx
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Fraser Health
Respiratory Disorder, Lung Infection
Evaluation of Virtual Reality to Reduce Anxiety, Pain and Duration of Non-emergency Vigile Bronchial Fibroscopy (AVATAR)
Bronchial fibroscopy (BF) is a routine practice examination in critical care areas. It can be useful either for the diagnosis of the causal pathology of respiratory distress or for the diagnosis of lung infection, sometimes…
- Trial name
- AVATAR (NCT05973201)
- Testing
- Virtual reality headset
- Where
- 5 sites in France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease, Coronary Thrombosis
Scripps Evaluation of Antiplatelet Therapies for Intermediate Duration With the Endeavor Stent (Seaside)
Despite the benefit of drug-eluting stents (DES) to reduce the need for repeat revascularization procedures, concerns regarding late stent thrombosis (ST) have led to recent guidelines advocating extended prescription of dual…
- Trial name
- SEASIDE (NCT00963781)
- Testing
- Medtronic Endeavor Stent, Reduced duration (6 months) DAPT
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- Scripps Health
Atopic Dermatitis, Pruritus
Observational Analytical Validation Study of the Replior ScratchSense
Nocturnal scratching is a frequent and meaningful symptom in dermatological conditions such as atopic dermatitis. It may reflect underlying disease activity and can substantially disrupt overall sleep and quality of life.
- Conditions
- Atopic Dermatitis, Pruritus, Chronic Pruritus of Unknown Origin
- Trial name
- NCT07909967
- Testing
- Scratch and sleep research tracking
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Replior AB
Prostate Cancer, Diffusion MRI
MR Microstructural Imaging for Prostate Cancer Diagnosis
The goal of this multi-center clinical study is to evaluate whether time-dependent diffusion MRI (TDDMRI) can provide reliable microstructural imaging markers for the diagnosis of prostate cancer.
- Trial name
- NCT07249281
- Testing
- MRI/ MRS (Magnetic Resonance Imaging /Magnetic Resonance Spectroscopy)
- Where
- 6 sites in China
- Volunteers
- 2,000 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
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