Clinical trials: Investigation Time
Pediatric Cancer
Reducing Port Access Pain and Clinic Wait Time: An Evaluation of EMLA Cream Versus nüm™ Vapocoolant Spray
The goal of this clinical trial is to compare a sterile vapocoolant spray to EMLA cream in children with access ports. Participants will receive either the spray or cream prior to port access and rate pain on a scale.
- Trial name
- NCT06023368
- Testing
- Num Vapocoolant Spray, EMLA Cream
- Where
- United States
- Sponsor
- Marianne Hutti
Angina Pectoris
Blood Pressure Interaction Between Sildenafil and Sublingual Glyceryl Trinitrate (GTN) in Men With Angina
The purpose of the study is to determine for how long sildenafil potentiates the blood pressure reduction that occurs with glyceryl trinitrate in men with angina.
- Trial name
- NCT00479908
- Testing
- Sildenafil citrate, Glyceryl trinitrate
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Halitosis, Dentistry
Effect of Dental Education Duration on Halitosis and Associated Factors
The study population will consist of undergraduate dental students enrolled at Recep Tayyip Erdoğan University Faculty of Dentistry.
- Trial name
- NCT07740876
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Wounds
Oleogel-S10 in Wound Healing of Split-Thickness Skin Graft Donor Sites (BSG-12)
The main purpose of this phase III clinical trial was to show safety and efficacy of Oleogel-S10 in accelerating the wound healing of Split-Thickness Skin Graft (STSG) donor sites.
- Trial name
- BSG-12 (NCT01807650)
- Testing
- Oleogel-S10, non-adhesive wound dressing, Non-adhesive wound dressing only
- Where
- 14 sites in France, Greece and 2 more
- Volunteers
- 112 people
- Sponsor
- Birken AG
Bronchiolitis
Bronchiolitis: Evaluation of Wang's Score as a Predictor of the Duration of Oxygen Therapy in Bronchiolitis
Evaluation of Wang's score as a predictor of the duration of oxygen therapy in bronchiolitis
- Trial name
- NCT03362125
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Rennes University Hospital
Factors Determining Time Allocation of a Multiple-Choice Question Examination
Factors Determining Time Allocation of a MCQ Examination
The MCQ is one of the objective assessment methods. It is proper to evaluate the cognitive domain of learners with high objectivity. However, there are no definite criteria for determining the appropriate exam time.
- Trial name
- NCT06210997
- Testing
- Questionaires
- Where
- Thailand
- Volunteers
- 298 people
- Sponsor
- Suranaree University of Technology
Tuberculosis
First Time in Human (FTIH) Safety and Pharmacokinetics (PK) Study of GSK3036656 in Healthy Subjects
GSK3036656 is being developed by GSK for the treatment of tuberculosis (TB). This is the FTIH study for GSK3036656 to evaluate the safety, tolerability and PK of single ascending and repeat oral doses of GSK3036656 in healthy…
- Trial name
- NCT03075410
- Testing
- GSK3036656
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Participants
Study to Evaluate Bioavailability of a Single 12 mg Dose of Perampanel for Three Intravenous Infusion Durations Relative to a Single 12 mg Perampanel Oral Tablet in Healthy Subjects
This study will be conducted to evaluate the bioavailability of a single 12 milligram (mg) dose of perampanel intravenous infusions of different durations relative to a single 12 mg dose of perampanel oral tablet in healthy…
- Trial name
- NCT03376997
- Testing
- Perampanel
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Sleep
Sleep in Pediatric Intensive Care Patients
This research will be carried out experimentally in order to investigate the Effect of Sleep Band and White Noise Use on the Time to Sleep in Pediatric Intensive Care Patients aged 3-12 months.
- Trial name
- NCT05432076
- Testing
- Sleep Band and White Noise
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ebru Kilic
Cystic Fibrosis (CF)
MRI Assessment of Lung Airways in Cystic Fibrosis: Evaluate MRI's Ability to Detect Changes in Airway Structure .
This study is being done to determine whether MRI can produce high quality lung and airway images in healthy and CF patients and if MRI can be used to evaluate size and shape of the airways with computer assistance.
- Trial name
- UTE Airway MR (NCT07454681)
- Testing
- Advanced ultrashort echo time (UTE) MRI - Ultrashort echo time (UTE) imaging is a technique that can quickly capture the fast-decaying 1H lung signal., Multiple Breath Wash out (MBW)
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Inflammatory Bowel Diseases
A First Time In Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of GSK1399686
A First-Time-in-Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of GSK1399686 After Single and Repeated Oral Dosing in Healthy Volunteers
- Trial name
- NCT00721812
- Testing
- GSK1399686
- Where
- United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Moderate to Severe Glabellar Lines
A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
The purpose of this study is to assess the effectiveness and safety of a single dose of Corabotase (also known as IPN10200) compared to placebo (double-blind phase) and how well and safely repeat doses of Corabotase work over…
- Trial name
- LAURITE 2 (NCT07435428)
- Testing
- Corabotase
- Where
- 60 sites in United States, France and 2 more
- Volunteers
- 1,300 people
- Sponsor
- Ipsen
Mental Disorders
Evaluation of an Intervention to Promote Physical Activity in Outpatients With Mental Disorders
The purpose of this study is to determine if a manualised intervention to promote physical activity (MoVo-LISA) is effective to help psychiatric outpatients to increase their level of everyday physical activity.
- Trial name
- GAF (NCT02569619)
- Testing
- Activity Intervention, Healthy Diet Intervention
- Where
- Germany
- Volunteers
- 86 people
- Sponsor
- Charite University, Berlin, Germany
Postoperative Ileus
Postoperative Ileus: Duration and Severity Assessment With the SmartPill®
Postoperative ileus (POI) is a frequent complication after abdominal surgery leading to nausea, vomiting and infectious complications.
- Trial name
- PIDuSA (NCT02329912)
- Testing
- SmartPill
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- University Hospital, Bonn
Allodynia
Evaluation of the Efficacy of Somatosensory Rehabilitation of Pain by Vibrotactile Stimulation on Static Mechanical Allodynia
This study aims to demonstrate that somatosensory rehabilitation of pain associated with static mechanical allodynia has superior efficacy over placebo treatment as well as over spontaneous changes.
- Trial name
- RESISTAL (NCT02571010)
- Testing
- Standard Medical treatment, Vibrotactile stimulation
- Where
- France
- Volunteers
- 17 people
- Sponsor
- CRRF La Châtaigneraie
Pressure Incidence Prevention
Pressure Injury Prevention in the ICU With Multi-Layer Foam Dressings
A Multi-Centre, Open, Non-controlled, Clinical Investigation to Evaluate the User Friendliness and Wear Time of Multi-layer Foam Dressings With Safetac® for Pressure Injury Prevention in the Intensive Care Unit
- Trial name
- PUP16_01 (NCT02962882)
- Testing
- Mepilex Border
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Molnlycke Health Care AB
Chronic Obstructive Pulmonary Disease
Short Antibiotic Treatment Versus Duration Guided by Markers of Inflammation in the Treatment of AECOPD
Chronic obstructive pulmonary disease (COPD) is one of the most common diseases in the world. In a recent study, we showed that administration of levofloxacin is superior to placebo in the treatment of decompensation of COPD; it…
- Trial name
- AECOPD (NCT02067780)
- Testing
- Levofloxacin 500mg
- Where
- Tunisia
- Volunteers
- 310 people
- Sponsor
- University of Monastir
Gastric Emptying, Preoperative Risk Assessment
Stomach Processing and Emptying Evaluation With Diet and Ultrasound
Gastric content is a key risk factor for aspiration during anesthesia. Although standard fasting times are recommended, various factors-including GLP-1 receptor agonists,-can delay gastric emptying.
- Conditions
- Gastric Emptying, Preoperative Risk Assessment, Healthy Volunteer Study
- Trial name
- SPEED-US (NCT06988397)
- Testing
- Physical activity after different type of meals
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Diabetes Mellitus, Type 2
Assessment of Duration of Metabolic Effect of a Single Bolus of sc Injected Lantus Compared to NPH Insulin in Patients With Type 2 Diabetes
To assess the duration of the metabolic effect of a sc injected single dose of either insulin glargine (LantusT) or NPH-insulin (ProtaphanT) on blood glucose control in patients with type 2 diabetes
- Trial name
- NCT00553020
- Testing
- Insulin glargine
- Volunteers
- 16 people
- Sponsor
- Sanofi
Infertility
Artificial Intelligence in Embryo Selection in Assisted Reproduction for Embryos Cultured to the Fifth Day of Development
Embryo selection is one of the major challenges in Assisted Reproductive Technology (ART) in order to continuously improve clinical pregnancy rates.
- Trial name
- IASEAMP (NCT07844083)
- Testing
- EMA
- Where
- France
- Volunteers
- 550 people
- Sponsor
- University Hospital, Clermont-Ferrand
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