Clinical trials: Investigation Time
Delirium
Nursing Intervention to Reduce Incidence and Duration of Delirium in Patients in Intensive Care
Introduction: Delirium is a cognitive alteration of acute onset and fluctuating course, characterized by the reduced capacity to pay attention to the environment, memory impairment, disorientation, language, and perception…
- Trial name
- NCT05172583
- Testing
- Control, Interventions to reduce delirium based on DSM and scientific evidence
- Where
- Colombia
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Universidad Surcolombiana
To Verify Tissue Heating and Temperature Stability and Safety Throughout RF Treatment Duration Applied on the Face
Evaluation of Thermal Outcome and Safety of Nuera Tight RF System
The purpose of the study is to verify tissue heating, temperature stability and safety of the Nuera Tight RF device during and after treatment session applied on the face.
- Trial name
- NCT05957029
- Testing
- NuEra Tight RF system
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Overactive Bladder Syndrome
A 12-Week Study to Evaluate the Efficacy of Darifenacin to Increase the Warning Time in Patients With Overactive Bladder.
This study will assess the efficacy of a 12-week treatment with darifenacin in increasing warning time, the time from first sensation of urgency to voiding, in patients with OAB.
- Trial name
- NCT00171145
- Testing
- Darifenacin
- Where
- United States
- Volunteers
- 445 people
- Sponsor
- Novartis
Pneumonia
Evaluation of Integrated Community Case Management in Ethiopia
The purpose of this study is to to measure the effect of the HEP+ICCM program relative to routine HEP approach in rural Ethiopia on changes in coverage of case management of common childhood illnesses and severe acute…
- Trial name
- NCT01606267
- Testing
- health systems intervention: HEP+ICCM
- Where
- Ethiopia
- Volunteers
- 607,770 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Constipation
Assessment of Whole Gut Transit Time Using the SmartPill Capsule
Our null hypothesis states that the two techniques (Sitzmarks radioopaque markers and SmartPill) are equivalent and is demonstrated if the study population shows a correlation of 0.7 or higher.
- Trial name
- WholeGut (NCT00603707)
- Where
- 8 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- The SmartPill Corporation
Malaria
A First Time in Human Study in Healthy Volunteers to Investigate a New Medicine to Treat Malaria
The purpose of this study is to determine if the study drug (antimalarial medication) is safe when given to healthy subjects as a single dose or as repeated doses, to understand the effect of food on single doses of study drug…
- Trial name
- NCT00811356
- Testing
- GSK932121; Rosiglitazone; Rosuvastatin
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Coronary Artery Disease
Evaluation of Zotarolimus Eluting Stent at 3 Months Using Optical Coherence Tomography
Neointimal coverage over stent strut is important for preventing the stent thrombosis. But, there is no data for the duration of complete formation of neointima om zotarolimus eluting stent (ZES).
- Trial name
- ENDEAVOR OCT (NCT00815139)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Disorder of Consciousness, Consciousness, Loss of
SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury
Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models.
- Conditions
- Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury
- Trial name
- NCT06083441
- Testing
- SeeMe, Coma Recovery Scale-Revised (CRS-R)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
The Device Placement Times, Intubation Times
Evaluation of Differences in Video Laryngeal Mask Airway and Fastrack Laryngeal Mask
In our study, patients who are intubated using VLM and Fastrack LMA for intubation purposes will be included. The placement times, intubation times, and the number of failed attempts for both devices will be recorded.
- Conditions
- The Device Placement Times, Intubation Times, Postoperative Complications
- Trial name
- NCT06121895
- Testing
- Video Laryngeal Mask, Fastrack Laryngeal Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Ankara Etlik City Hospital
Dry Eye Syndrome
Assessment of Tear Film Thickness by Optical Coherence Tomography in Healthy Subjects and Subjects With Dry Eye Disease
Dry eye syndrome (DES) is a highly prevalent ocular condition with severe consequences for the patients reaching from ocular discomfort in its simplest form up to visual impairment and corneal ulceration in severe cases.
- Trial name
- NCT01753596
- Testing
- GENTEAL HA® Eye Drops (NOVARTIS, Switzerland), Physiological Sodium Chloride solution (0,9%)
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Type 1 Diabetes
Study to Assess the Metabolic Impact of IRTA© and Patients Satisfaction in Type 1 Diabetic Patients, Treated by Either Insulin Pump or Multiple Daily Insulin Injections, and Using Freestyle Libre®, a Real-time Continuous Glucose Monitoring
A prospective monocentric " before and after " study, ruled in 2 periods of 3 months : during the first period, the patient will adjust insulin treatment as usual, during the second period, the patient will adjust insulin…
- Trial name
- IRTA (NCT04211220)
- Testing
- A decision support software
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Rennes University Hospital
Type 2 Diabetes Treated With Insulin
A Study to Evaluate Time in Range in Type 2 Diabetics Using Afrezza® Plus Basal Insulin Compared to Multiple Daily Injections
The purpose of this study is to collect CGM, A1c and Quality of Life data in subjects with Type 2 diabetes before and after transitioning from Multiple Daily Injections to Basal plus Bolus with Afrezza® inhaled insulin.
- Trial name
- NCT04125082
- Testing
- Afrezza Inhalant Product
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Diabetes and Glandular Disease Clinic
Copd
Assessment of Pulmonary Functions and Peripheral Muscle Strength of COPD Patients in Different GOLD Stages
The purpose of this research was to examine the respiratory functions, respiratory muscle strength and peripheral muscle strength of patients with COPD in different groups and to evaluate their correlation with the duration and…
- Trial name
- NCT04803656
- Testing
- Assessment of COPD patients
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Marmara University
Ulcerative Colitis
Development and Validation of a Deep Learning Algorithm to Evaluate Endoscopic Disease Activity of Ulcerative Colitis.
The purpose of this study is to develop an artificial intelligence(AI) assisted scoring system, which can evaluate the disease severity and mucosal healing stage in patients with ulcerative colitis.
- Trial name
- NCT03973437
- Testing
- Artificial inteligence associated ulcerative colitis severity scoring system, Conventional human scoring
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shandong University
Hypertriglyceridemia
A Phase 1, First Time in Humans Study of NST-1024
A first time in man study of NST-1024
- Trial name
- NCT04630366
- Testing
- NST-1024
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- NorthSea Therapeutics B.V.
Open-Angle Glaucoma, Ocular Hypertension
Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension
This study evaluates the duration of intraocular pressure (IOP)-lowering effect and safety of as needed administrations of Bimatoprost sustained release (SR) in participants with open-angle glaucoma (OAG) or ocular hypertension…
- Trial name
- TRITON (NCT03850782)
- Testing
- Bimatoprost (SR)
- Where
- 108 sites in United States, Argentina and 14 more
- Volunteers
- 515 people
- Sponsor
- AbbVie
Pharmacokinetics
Effect of Ketoconazole on Sufentanil NanoTab Pharmacokinetics
Evaluate the effect of taking ketoconazole on sufentanil plasma concentrations following sublingual administration of sufentanil NanoTab.
- Trial name
- NCT01721070
- Testing
- Sufentanil NanoTab (SUF NT) 15 mcg, Ketoconazole 400 mg, sufentanil NanoTab (SUF NT) 15 mcg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Talphera, Inc
Accelerometry
A Smartphone Application to Evaluate Energy Expenditure and Duration of Moderate-intensity Activities
The aim of this study was to find functions for estimating energy expenditure in free-living conditions. This method was based on accelerometry data acquired from a smartphone worn in a trouser pocket.
- Trial name
- NCT01995253
- Testing
- Energy expenditure estimation in controlled conditions, Energy expenditure estimation in free-living conditions
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Preterm Labour, Preterm Birth
Evaluation of a Novel Diagnostic Kit for the Detection of Placental Alpha-Microglobulin-1 in the Prediction of Preterm Birth
This is a prospective observational trial that will enroll pregnant women between 24 and 36 6/7 weeks of gestation that present with signs and symptom of preterm labor with clinically intact membranes and cervical dilatation ≤ 3…
- Trial name
- NCT02092688
- Testing
- novel kit for the detection of PAMG-1
- Where
- Switzerland
- Volunteers
- 126 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Orthognathic Surgery
3D Printed Models in 3D Virtual Treatment Planning of Orthognathic Surgery
Despite the shift from 2D towards 3D virtual treatment planning of orthognathic surgery, traditional plaster cast are still gold standard.
- Trial name
- NCT03986723
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- AZ Sint-Jan AV
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