Clinical trials: Investigation Time
Cardiopulmonary Resuscitation, Education
Efficacy of Online Real-time CPR Training
The purpose of this study is to evaluate the effectiveness of a new online real-time quality measurement and feedback video-based CPR training program.
- Trial name
- NCT04656405
- Testing
- Online real-time quality measurement and feedback video-based CPR training, Online real-time feedback video-based CPR training without quality measurement, Conventional CPR training
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hyperactive Masseter Muscle
Evaluation the Efficacy of Zinc on Botulinum Toxin A Injection
This clinical trial seeks to investigate a promising new approach to enhance the effectiveness and duration of Botulinum Toxin A (BTX-A) for the treatment of hyperactive masseter muscles.
- Trial name
- BTX-A (NCT07270042)
- Testing
- BOTOX 100U in normal saline with zinc
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latakia University
Benign Uterine Diseases
Feasibility and Benefit of Laparoscopic Hysterectomy With Less Than 3 Millimeter Diameter's Instruments in Current Practice
Hysterectomy for benign uterine disease is often intended to young perimenopausal patients. Currently laparoscopic hysterectomy is commonly used in this indication.
- Trial name
- NCT02367703
- Testing
- laparoscopic hysterectomy
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Failure
Study to Evaluate Potential Decrease in Hospitalization Events, Time Between Events, and Increasing Longevity in Patients With Symptomatic Heart Failure (0954-948)
This is a multicenter study to evaluate potential decrease in hospitalization events and time between events and increasing longevity in patients with symptomatic congestive heart failure and intolerant of first-line medication…
- Trial name
- NCT00090259
- Testing
- Losartan 50 mg, Losartan 150 mg
- Volunteers
- 3,834 people
- Sponsor
- Organon and Co
Labor, Parturition
Sling and Swing Positions to Pregnant Women
It is an experimental and randomized controlled study planned to evaluate the effect of sling-swinging position on the birth experience in vaginal delivery.
- Conditions
- Labor, Parturition, Delivery
- Trial name
- NCT05708482
- Testing
- Sling-Swing Position
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Artificial Intelligence
A Study to Assess the Impact of an Artificial Intelligence (AI) System on Chest X-ray Reporting
The study has an initial short retrospective component but is predominately a prospective study with two main parts. Initially during a 1 month period whilst reporters are familiarising themselves with the software two local…
- Trial name
- NCT05489471
- Testing
- Artificial intelligence review
- Volunteers
- 20,000 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Crime
The Time Before the Crime - Risk Patterns in Offenders Undergoing a Forensic Psychiatric Evaluation
The overarching aim of the research project is to identify risk patterns preceding criminal acts among individuals later subject to forensic psychiatric evaluation (FPE) in Sweden, including factors within psychiatric care as…
- Trial name
- Tibec (NCT07162909)
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Karolinska Institutet
Colonoscopy
Evaluation of the Use of Cap in Improving the Performance of Colonoscopy
The aim of this study is to compare the colonoscopy success rate, cecal time and polyp detection rate between cap-fitted colonoscopy and conventional colonoscopy.
- Trial name
- NCT00930462
- Testing
- Cap (Olympus Medical Systems: D-201-15004, D-201-14304 and D-201-12704)
- Where
- Australia
- Volunteers
- 400 people
- Sponsor
- Royal Prince Alfred Hospital, Sydney, Australia
Early Stage Breast Cancer
Shaving as an Safe Alternative to Frozen Section Analysis
Evaluation of Tumor Bed Cavity Shaving as an Oncologically Safe Alternative to Frozen Section Analysis in Breast-Conserving Surgery and aim of study To assess the oncological safety and practicality of tumor bed cavity shaving…
- Trial name
- NCT07244588
- Testing
- Tumor bed cavity shaving
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mark Ezzat Gerges
Prostate Cancer, Metastatic Castration-Resistant Prostate Cancer
A Phase I Trial of A-CAR032 in Participants With mCRPC
This FTiH, single-arm, open-label, investigator-initiated Phase I trial will evaluate the safety, antitumour activity, CK/pharmacodynamics (PD), biomarkers, immunogenicity, and feasibility of A-CAR032 in adult participants with…
- Trial name
- NCT07344311
- Testing
- dnTGFβRII-armoured STEAP2-targeted autologous CAR T-Cell Injection
- Where
- 4 sites in China
- Volunteers
- 27 people
- Sponsor
- Shanghai AbelZeta Ltd.
AMD, nAMD
Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMD
ABBV-RGX-314 (also known as RGX-314) is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD or nAMD).
- Conditions
- AMD, nAMD, Wet Age-related Macular Degeneration, wAMD
- Trial name
- ATMOSPHERE (NCT04704921)
- Testing
- ABBV-RGX-314, Ranibizumab (LUCENTIS®)
- Where
- 89 sites in United States
- Volunteers
- 671 people
- Sponsor
- AbbVie
Bone Marrow Transplantation
An Adaptive Phase I Study to Evaluate the Safety, Efficacy and Dose Responses of Ronacaleret in Healthy Human Volunteers
Ronacaleret is an orally administered CaSR antagonist which has previously been demonstrated to transiently increase PTH in both animals and humans.
- Trial name
- NCT01466335
- Testing
- Ronacaleret (100mg tablet)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dyspeptic Subjects
Phase 2 Study to Evaluate the Preliminary Performance of the C13-URA Breath Test Kit in Dyspeptic Subjects
This study is a multi-center, open-label comparison study and aimed to evaluate the preliminary performance of this 13C-uracil GEBT to examine its abilities of identifying abnormal (delayed) gastric emptying rates in subjects.
- Trial name
- NCT01677338
- Testing
- 13C-uracil, 99mTc sulfur colloid
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Color Blindness, Red, Reaction Time
Effect of Protanopia on the Brightness Perception of Brake Lights
The aim of the offered project is to investigate the influence of protanopia (red blindness) or protanomaly (red vision weakness) on the recognizability of red brake lights with the help of a test person study.
- Trial name
- ProLight (NCT04060238)
- Testing
- Anomaloscope (colour vision test)
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Aalen University
Bronchiectasis
Ciprofloxacin Dry Powder for Inhalation (DPI) in Non-cystic Fibrosis Bronchiectasis (Non-CF BE)
The purpose of this study is to evaluate if the time to first pulmonary exacerbation of bronchiectasis or its frequency can be prolonged by inhalation of ciprofloxacin for 28 days every other 28 days or for 14 days every other 14…
- Trial name
- RESPIRE 2 (NCT02106832)
- Testing
- Ciprofloxacin (BAYQ3939) dry powder for inhalation
- Where
- 207 sites in United States, Argentina and 23 more
- Volunteers
- 521 people
- Sponsor
- Bayer
Prostate Cancer
Response of Patients on Surveillance for Prostate Cancer to Dutasteride
Hypothesis: That, in men on surveillance for favorable risk prostate cancer treated with dutasteride, prostate specific antigen (PSA) kinetics is of value in identifying those men who harbor occult high grade prostate cancer.
- Trial name
- NCT01525914
- Testing
- Dutasteride
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Type 1 Diabetes
Study of Insulin Therapy Augmented by Real Time Sensor IN Type 1 Children and Adolescents (START-IN!)
Glycemic control in children and adolescent with type 1 diabetes remains inadequate, exposing them to the risk of vascular complications in adulthood.
- Trial name
- START-IN (NCT00949221)
- Testing
- monitor Paradigm 754 VEO, MINILINK Real Time, Medtronic, CE
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 2 Diabetes Mellitus
A Study To Investigate The Safety And Metabolism Of GSK376501 In Overweight Subjects
This study represents the first administration of GSK376501 in humans and the goal is to evaluate its initial safety and tolerability. The way the human body processes GSK376501 will also be determined.
- Trial name
- NCT00404963
- Testing
- GSK376501
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Candidiasis, Oral, HIV Infections
The Safety and Effectiveness of Peridex in Preventing or Delaying Fungal Infections of the Mouth in HIV-Infected Patients
To evaluate the safety and effectiveness of Peridex (an oral rinse containing chlorhexidine gluconate) for preventing the occurrence of clinically-evident microbiologically-documented oral candidiasis in HIV-positive patients…
- Trial name
- NCT00002431
- Testing
- Chlorhexidine gluconate
- Where
- 5 sites in United States
- Sponsor
- Procter and Gamble
Irritable Bowel Syndrome
A Phase I, Randomized, Placebo-controlled, Double Blind, Repeat Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Gastrointestinal Transit Time and Pharmacodynamic Biomarkers of GSK3179106 in Normal Subjects
The current study is designed to assess the safety, tolerability, pharmacokinetics (PK), gastrointestinal (GI) transit time and pharmacodynamic (PD) biomarkers of repeat oral doses of GSK3179106 administered for 14 days in normal…
- Trial name
- NCT02798991
- Testing
- GSK3179106
- Where
- Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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