Clinical trials: Investigation Time
Dry Eye
Residence Time Evaluation of Marketed OTC Ophthalmic Products
The objective of this study is to measure ocular surface residence time (in minutes) of two marketed OTC ophthalmic products in dry eye patients.
- Trial name
- NCT00804791
- Testing
- Systane Ultra Lubricant Eye Drops, Unisol 4 Saline Solution
- Volunteers
- 25 people
- Sponsor
- Alcon Research
Human Papillomavirus Virus
Observational Follow up of Prior HPV Vaccinees
HPV vaccines have been included in the national immunisation schedule since 2008, firstly as the Cervarix vaccine which protects against two HPV types and in 2012 as the Gardasil vaccine which offers protection against a further…
- Trial name
- HPVfollowup (NCT02811068)
- Testing
- venepuncture
- Where
- 2 sites in United Kingdom
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Public Health England
Thyroid Eye Disease
TEPEZZA® (Teprotumumab-trbw) Post-Marketing Requirement Study
This is a double-masked, randomized, parallel-assignment, multicenter trial examining the safety and tolerability of teprotumumab in the treatment of Thyroid Eye Disease (TED) in adult participants.
- Trial name
- NCT05002998
- Testing
- Teprotumumab
- Where
- 28 sites in United States, France and 4 more
- Volunteers
- 313 people
- Sponsor
- Amgen
Autologous Transplantation
Alteration in Timing of Plerixafor Administration
Typically, the collection of blood cells for autologous stem cell transplant is done after the drugs granulocyte colony-stimulating factor (G-CSF) and plerixafor have been given to activate the bone marrow stem cells to produce a…
- Trial name
- NCT01149863
- Testing
- Plerixafor
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Emory University
Low-Grade or Follicular B-Cell Non-Hodgkin's Lymphoma
Treatment of Relapsed Low-Grade or Follicular Lymphoma With Rituximab (Also Known as Rituxan, IDEC-C2B8, IDEC-102)
Rituximab is an antibody made in a laboratory. It binds to lymphoma cells and kills them. Treatment of recurrent B-cell lymphoma with rituximab may delay or prevent relapses.
- Trial name
- NCT00168740
- Testing
- rituximab
- Where
- 31 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- Biogen
Severe Sepsis
Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated)
In this trial, patients with severe sepsis and low protein C levels will receive drotrecogin alfa (activated) at the normal, approved dose and time of administration [24 microgram/kilogram/hour (mcg/kg/hour) for 96 hours] or will…
- Trial name
- NCT00386425
- Testing
- Drotrecogin alfa (activated)
- Where
- 47 sites in United States, Belgium and 7 more
- Volunteers
- 486 people
- Sponsor
- Eli Lilly and Company
Continuous Glucose Monitoring System, Accuracy
Assessment of the Accuracy,Feasibility,Safety of Continuous Glucose Monitoring System
Real-time continuous glucose monitoring system (CGMS) has been attempted to be used in ICU, but its feasibility, accuracy and confounding factors are controversial.
- Conditions
- Continuous Glucose Monitoring System, Accuracy, Feasibility, Safety
- Trial name
- NCT03120091
- Testing
- Real-time continuous blood glucose monitoring system(CGMS)
- Where
- China
- Volunteers
- 22 people
- Sponsor
- West China Hospital
Lymphoma, Large B-Cell, Diffuse
Prospective Data Collection of Elderly Patients With DLBCL Receiving at the Time of Diagnosis VGM
Prospective data collection of a consecutive series of elderly patients with large B-cell lymphoma newly diagnosed, receiving before the start of treatment Multidimensional Geriatric Assessment (VGM) through the use of Activity…
- Trial name
- NCT02364050
- Where
- 55 sites in Italy
- Volunteers
- 1,300 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Generalized Anxiety Disorder
Investigation Of How PD 0332334 And Metformin Are Eliminated From The Body When They Are Administered At The Same Time
1. To estimate the effects of multiple doses of PD 0332334 on the elimination of a single dose of metformin from the body 2. To estimate the effects of multiple doses of metformin on the elimination of a single dose of PD 0332334…
- Trial name
- NCT00809536
- Testing
- Metformin, PD 0332334
- Where
- Singapore
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Kidney Calculi, Pain, Postoperative
Pre-induction Analgesia: Multimodel Regimen vs Aceteminophen for Post Ureteroscopy Pain
Adult patients with kidney stones undergoing surgical intervention with ureteroscopy with laser lithotripsy will be randomized to receive one of two different regimens of oral medications administered prior to induction of…
- Trial name
- MMPITR (NCT03549611)
- Testing
- Multimodal Oral Drug Regimen, Acetaminophen
- Sponsor
- Kevin J Flynn MD
Stroke Rehabilitation
Hospitalisation Duration in Stroke Patients
The stage at which functional recovery stops during the rehabilitation programme and which is one of the important determinants of the discharge decision is called "plateau".
- Trial name
- NCT07229053
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ankara Etlik City Hospital
Fluid Resuscitation, Fluid Responsiveness Predictability
Evaluation of the Variation of the Sub-pulmonary Velocity-time Integral to Predict Fluid Responsiveness
Fluid administration is the first-line treatment in hypovolemic states in critically ill patients. Prediction of fluid responsiveness is possible with echocardiography by assessing the variation of the sub-aortic velocity-time…
- Trial name
- NCT07202637
- Testing
- Fluid bolus administration
- Where
- 2 sites in France
- Volunteers
- 205 people
- Sponsor
- Hospital Nord
Sensory Science, Performance Assessment
Personalized Performance Optimization Platform
Crews of future long-duration exploration missions will have to cope with a wide range of stressors that present significant challenges for maintaining optimal performance.
- Conditions
- Sensory Science, Performance Assessment, Countermeasure Evaluation, Neurocognitive Function
- Trial name
- P-POP (NCT06979570)
- Testing
- AttentivU
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Keloid Scar Following Surgery, Scars, Hypertrophic
Measuring the Volumes of Hypertrophic Scars and Keloids, Two Specific Kind of Scars, Over Different Points in Time in Patients Who Have Undergone Surgery and Evaluate 3D-cameras As a Possible Measuring and Documenting Tool Including Volumetry
Measuring the volumes of hypertrophic scars and keloids, two specific kind of scars, over different points in time in patients who have undergone surgery and evaluate 3D-cameras as a possible measuring and documenting tool…
- Conditions
- Keloid Scar Following Surgery, Scars, Hypertrophic, Scar Keloid
- Trial name
- NCT06806735
- Testing
- 3D-Pictures
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Non-carious Cervical Lesions
Evaluation of the Solvent Evaporation Time of Universal Adhesives in the Quality of Cervical Lesions Restorations
The aim of this study will be to evaluate the effect of prolonging solvent evaporation time on the 6- and 12-months clinical performance of two universal adhesive systems used as selective enamel etch (SEE).
- Trial name
- NCT05945173
- Testing
- Evaporation time for 5 seconds, Evaporation time for 25 seconds, alcohol/water-based universal adhesive
- Where
- Chile
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Candida
Candida PCR Diagnosis Strategy in Patients From Intensive Care Units
The aim of this study is to evaluate the implementation of a new technique for invasive candidiasis diagnosis by PCR. The main objective will be to evaluate the effect of this strategy on the time required to obtain results in…
- Trial name
- CANDI-PCR (NCT04874441)
- Testing
- Diagnosis strategy based on C. glabrata / krusei PCR
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Toulouse
Healthy Volunteers
A Brain Imaging Study With Positron Emission Tomography and the Radiotracer [11C]UCB-J to Estimate How Fast Brivaracetam and Levetiracetam Enter the Brain in Healthy Volunteers
This study will estimate how fast two antiepileptic drugs (Levetiracetam and Brivaracetam) enter the human brain. Brain imaging will be used to measure how quickly the radioactive probe [11C]UCB-J exits the brain when…
- Trial name
- NCT02602860
- Testing
- [11C]UCB-J, Brivaracetam, Levetiracetam
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- UCB Pharma
Mechanical Dyssynchrony, Heart Failure
Evaluating Effects of a Left Bundle Branch Block
A left bundle branch block (LBBB) is related to abnormal cardiac conduction and mechanical asynchrony and is associated with hypertension and coronary artery disease.
- Conditions
- Mechanical Dyssynchrony, Heart Failure, Bundle-Branch Block
- Trial name
- NCT00269659
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Prematurity of Fetus, Low Birth Weight Baby
Daily Skin-to-Skin Contact Duration in Preterm and Low Birth Weight Infants Admitted to a Kangaroo Care Unit
Kangaroo Mother Care promotes prolonged skin-to-skin contact between newborns and their parents. Although this practice is routinely encouraged in Kangaroo Care Units, the daily duration of skin-to-skin contact varies…
- Trial name
- PAP-UK (NCT07747870)
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Centre Hospitalier de Valenciennes
Newborns
Evaluation of the Effect of Duration of Stabilising Tapes on Skin Damage in Neonates
The research was conducted to evaluate the relationship between the duration of the fixing tapes of the probes attached to the chest, abdominal and lower extremity regions of newborns for temperature monitoring and skin damage.
- Trial name
- NCT06944054
- Testing
- Group 1
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
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