Clinical trials: Iron
Sickle Cell Disease, Thalassemia
Effects of Transfusion of Older Stored Red Cells
The purpose of this study is to determine the effects of transfusion of fresh and stored blood on patients. The investigators hope to test: whether a similar effect (older stored blood is associated with worse outcomes) is seen…
- Trial name
- NCT01534676
- Testing
- Transfusion, Blood, Chelation therapy
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hookworm Infection, Hookworm Disease
Safety and Immunogenicity Study of Na-GST-1 With or Without CpG
Na-GST-1 is a protein expressed during the adult stage of the hookworm life cycle that is thought to play a role in the parasite's degradation of host hemoglobin for use as an energy source.
- Trial name
- NCT02143518
- Testing
- Na-GST-1/Alhydrogel®, CpG 10104
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Iron, Abnormal Blood Level, Other Abnormal Blood Chemistry
Fresh Versus Old Red Blood Cells for Transfusion
Packed red blood cell units destined for transfusion can be stored for up to 42 days prior to transfusion based on Food and Drug Administration (FDA) guidelines.
- Trial name
- NCT01319552
- Testing
- Fresh transfusion, Old transfusion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Columbia University
Iron-refractory, Iron-deficiency Anemia (IRIDA)
Pharmacokinetics and Absolute Bioavailability of Fer-In-Sol and Triferic Administered Orally With Shohl's Solution in Healthy Volunteers
The main purpose is to determine the pharmacokinetics (PK) of Triferic iron administered orally in healthy adult volunteers. It is a randomized multiple treatments, single dose study.
- Trial name
- NCT02767128
- Testing
- Triferic, Fer-In-Sol, Shohl's solution
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Rockwell Medical Technologies, Inc.
Anemia in Pregnancy
Once Versus Twice Daily Iron Supplementation in Pregnant Women
The investigators will randomize women diagnosed with anemia in the mid-trimester of pregnancy to once or twice daily iron supplementation
- Trial name
- NCT02839096
- Testing
- Ferrous Sulfate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Healthy
Measurements of Body Iron Excretion of Healthy Adults
This is an observation study of subjects who previously had iron-55 isotope administered in studies of iron absorption. By determining the retention of the isotope in blood during a 3-year period, body iron excretion can be…
- Trial name
- NCT00755105
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Iron Deficiency
Nutritional Education and the Prevention of Iron Depletion in Children 9 Months to 2 Years
Iron depletion in young children is common and may progress to iron deficiency anemia which is associated with irreversible neurodevelopmental effects. Efforts to prevent iron depletion are key to preventing these effects.
- Trial name
- NCT00907088
- Testing
- Healthy milk intake, Standard nutrition counselling
- Where
- Canada
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Fatigue, Iron Deficiency
Clinical Evaluation of Iron Treatment Efficiency Among Non-anemic But Iron-deficient Female Blood Donors
The purpose of this study is to determine the subjective response of iron substitution (Tardyferon®) on fatigue in women blood donors with a mean serum ferritin < 30ng/ml and to assess variation of ferritin and hemoglobin after a…
- Trial name
- ferdon (NCT00689793)
- Testing
- Ferrous sulphate
- Where
- Switzerland
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Iron-deficiency, Pregnancy Anemia
Feasibility or Oral Lactoferrin to Prevent Iron Deficiency Anemia in Obese Pregnancy
Maternal iron deficiency anemia is associated with maternal and infant mortality, spontaneous preterm birth, maternal postpartum hemorrhage, and neurocognitive defects in the neonate.
- Conditions
- Iron-deficiency, Pregnancy Anemia, Obesity
- Trial name
- NCT04810546
- Testing
- Jarrow Formulas Oral Bovine Lactoferrin Supplement
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Iron-deficiency
Sucrosom5al Iron Supplementation in Blood Donors
The aim of this descriptive/explorative pilot study is to examine the effects of supplementing a sucrosomial iron preparation in whole blood donors with iron deficiency for three months.
- Trial name
- NCT04250298
- Testing
- sucrosomial iron
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Iron Absorption
Iron Bioavailability of Fortified Oat Drink
This study will follow a double blinded randomized controlled study design to enroll 20 apparently healthy 6 year old children. The children will be fed with two different nutrient fortified oat drinks labeled with stable…
- Trial name
- NCT01423162
- Testing
- Dietary Intervention (with Vit C then without Vit C), Dietary Intervention (without Vit C followed by with Vit C)
- Where
- Philippines
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Anemia
Iron Depletion and Replacement in Blood Donors
The purpose of this study is to determine (1) the role of ferritin testing to screen for iron depletion in donors at risk of low iron levels (2) the effectiveness of oral iron replacement therapy on the repletion of iron stores…
- Trial name
- NCT01752413
- Testing
- Ferrous gluconate 325mg, Nutrition counseling
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Memorial Blood Centers, Minnesota
Kidney Failure, Chronic Therapy; Hemodialysis
A Single Ascending Dose Study of Soluble Ferric Pyrophosphate Administered Intravenously in Healthy Volunteers.
The purpose of this study is to determine the pharmacokinetics of fixed ascending doses of intravenously administered Soluble Ferric Pyrophosphate
- Trial name
- NCT01920854
- Testing
- soluble ferric pyrophosphate
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rockwell Medical Technologies, Inc.
Iron-deficiency Anemia, Iron-deficiency
Bloodsafe Ghana- Iron and Nutritional Counseling Strategy Pilot Study
This pilot study has 2 components: 1) a cross-sectional assessment designed to estimate the prevalence of anaemia leading to donor deferral, the prevalence of iron deficiency (ID) and iron deficiency anaemia (IDA) among…
- Trial name
- BLIS (NCT04949165)
- Testing
- Iron Supplementation
- Where
- Ghana
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tuberculosis, Iron Deficiency Anemia
Universal Screening for Tuberculosis and Anemia With the CHICA System
The CHICA system is a clinical decision support system that uses adaptive turnaround documents to provide point-of-care information to clinicians.
- Trial name
- NCT01322841
- Testing
- CHICA Diagnosis Module
- Where
- United States
- Volunteers
- 2,239 people, healthy volunteers welcome
- Sponsor
- Indiana University
Apical Periodontitis, Pulp Disease, Dental
A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment
The goal of this observational is study is to develop a protocol for root canal biofilms disinfection using a clinically approved and commercially available iron oxide nanoparticle formulation Ferumoxytol/H2O2 treatments.
- Trial name
- NCT06110494
- Testing
- Iron oxide nanoparticles treatment Ferumoxytol/H2O2, NaOCl, NaCl
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Iron, Blood Level Abnormal
Duration of Red Blood Cell Storage Prior to Transfusion
This study will determine the minimal duration of red blood cell (RBC) storage that leads to increases in circulating non-transferrin-bound iron in healthy human volunteers post-transfusion.
- Trial name
- NCT02087514
- Testing
- Blood Transfusion, Packed red blood cells
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Columbia University
Anemia
IV Iron Safety: Evaluation of Iron Species in Healthy Subjects
An approved treatment for anemia or low blood count due to chronic kidney disease is IV (intravenous, given into the vein) injection of an iron treatment. IV iron increases iron in the blood.
- Trial name
- NCT02399449
- Testing
- Brand sodium ferric gluconate, Generic sodium ferric gluconate
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Growth and Development
Investigation of Iron Uptake From Micronutrient Fortified Powder Versus From Tailored Control in Milk
The present study supplements iron as part of multiple micro-nutrient supplementation to demonstrate that intake of a micronutrient fortified powder in milk helps increase the uptake of key micronutrients like iron due to unique…
- Trial name
- NCT02254460
- Testing
- Test, Control
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Anemia
Evaluation of Natureheme-iron on Iron Absorption Effect and Anti-oxidation Functions
Iron deficiency problem has always been in Taiwan. This is a randomized, double-blind trial. Subjects separate to 3 groups, one group (n = 20) take two Natureheme-iron capsules a day for a total of 12 weeks, another group (n =…
- Trial name
- NCT02871128
- Testing
- Natureheme-iron, supplement
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University