Clinical trials: Iron
Neurodevelopmental Disorders, Lactation
Iron Supplement Effect on Child Development
Objective: To evaluate the effect of Iron supplement with two different amounts (one in the higher limit and another in the lower limit of the suggested amount) according to the presence of mutations in the HFE gene in the…
- Trial name
- NCT02690675
- Testing
- Iron fortified formula milk
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Iron Deficiency Anemia
Iron Indices and Intravenous Ferumoxytol: Time to Steady State
The purpose of this study is to evaluate the time point of transferrin saturation (TSAT) and ferritin stabilization after a thirteen-treatment period following a ferumoxytol load, as well as to determine the point at which serum…
- Trial name
- NCT01148745
- Testing
- ferumoxytol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Dialysis Clinic, Inc.
Postoperative Anaemia
The Use of Iron Therapy for Patients With Anemia After Caesarean Section
The purpose of this study is to determine whether oral or intravenous iron is effective in the treatment of anaemia (iron-poor blood) after caesarean section.
- Trial name
- VITAPOP (NCT01975272)
- Testing
- Ferinject, Ferrous fumarate
- Where
- 2 sites in Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Glioblastoma
Glioblastoma Imaging Using a Strong Iron-like Bloodpool Contrast Medium?
Rationale: Visualization of tumor spread is of crucial importance when treating patients suffering from glioblastoma (GBM) as the success of tumor resection depends strongly on the extent of tumor infiltration.
- Trial name
- NCT05656300
- Testing
- MRI scan using USPIO particles
- Volunteers
- 15 people
- Sponsor
- Radboud University Medical Center
İron Deficiency Anemia, Liposomal Iron Replacement
Liposomal vs Conventional Oral Iron After Sleeve Gastrectomy
Low-dose liposomal iron (17-34 mg elemental/day) was compared with standard conventional oral iron (100-200mg elemental/day) in the treatment of iron deficiency anemia following sleeve gastrectomy.
- Conditions
- İron Deficiency Anemia, Liposomal Iron Replacement, Conventional Iron Replacement
- Trial name
- anemia (NCT07366502)
- Testing
- Liposomal Iron, conventional oral iron
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Medeni Şermet
Anemic, Critically Ill Patients
Efficacy of Enteral Iron Supplementation in Critical Illness
The purpose of this study is to investigate the efficacy of enteral iron supplementation for improving anemia, decreasing the risk of blood transfusion, and decreasing mortality in patients who are hospitalized in the intensive…
- Trial name
- NCT00450177
- Testing
- Ferrous Sulfate
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Weill Medical College of Cornell University
Anemia, Iron Status
Daily and Weekly Iron Supplementation in Infants
This study aims to compare the efficacy of daily iron supplementation and weekly iron supplementation in infants aged 6-12 months on the prevalence of anemia, hemoglobin level, and serum ferritin levels.
- Conditions
- Anemia, Iron Status, Infants, Iron
- Trial name
- NCT06318858
- Testing
- Iron supplement
- Where
- Thailand
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Breast Neoplasm, Carcinoma, Ductal, Breast
Sentinel Lymph Node Identification in the Axilla of Women With Breast Cancer Using Ultrasound and Iron Injection
This study evaluates a new method of testing the lymph nodes in the armpit of patients with breast cancer for tumor involvement.
- Conditions
- Breast Neoplasm, Carcinoma, Ductal, Breast, Carcinoma, Intraductal, Noninfiltrating
- Trial name
- NCT02610920
- Testing
- Iron-tracer guided axillary ultrasound and biopsy, Iron tracer
- Sponsor
- Columbia University
Anemia
Using Iron With Procrit in Advanced Lung Cancer Patients With Chemotherapy-Induced Anemia
The purpose of this study is to find a better, more convenient way to improve anemia results by increasing the amount of medication given at 3 week intervals.
- Trial name
- Procrit (NCT00481624)
- Testing
- Epoetin Alfa plus Iron
- Where
- United States
- Sponsor
- University of Louisville
Anemia
High Dose IV Iron Plus ESA in Chemotherapy-induced Anemia
This study is a multicenter, prospective, randomized phase 3 clinical study comparing the efficacy and safety of the combination treatment of ESA and high-dose IV iron (darbepoietin alfa + ferric derisomaltose/iron isomaltoside)…
- Trial name
- NCT05768997
- Testing
- Ferric Derisomaltose Injection, Darbepoetin Alfa Injection
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- Hallym University Medical Center
Iron-deficiency, Iron Deficiency Anemia
Fatigue, Quality of Life, Cognitive Function and Physical Ability in Patients Suspected of Colorectal Malignancy
The aim is to investigate if iron deficiency at the time of colorectal cancer diagnosis has an influence on fatigue, quality of life, cognition and physical ability.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Colorectal Cancer, Fatigue
- Trial name
- NCT04749589
- Testing
- iron deficiency
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Beta-Thalassemia, Iron Overload
Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients
This is a randomized, open label, two arms superiority trial of a representative population of patients with a primary diagnosis of transfusion dependent thalassemia with evidence of moderate cardiac iron overload, defined as an…
- Trial name
- CANALI (NCT02474420)
- Testing
- Amlodipine, Deferasirox
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Kevin H.M. Kuo, MD, MSc, FRCPC
Hip Fracture, Anemia
IV Iron in Association With Tranexamic Acid for Hip Fracture
It is a prospective randomized controlled study aiming to test if tranexamic acid combined to intravenous iron before and after surgery for hip fracture in elderly can decrease peri-operative red cell transfusion.
- Trial name
- NCT02428868
- Testing
- tranexamic acid (Exacyl®), intravenous iron (Ferroven®), Saline
- Where
- Tunisia
- Volunteers
- 150 people
- Sponsor
- Institut Kassab d'Orthopédie
Iron-deficiency
Stable Iron Isotope Method in HIV+ and HIV- Children
The objective of this study is to compare HIV infected children to uninfected children regarding 1) quantifying iron absorption from iron fortified maize porridge, lipid-based food supplements and oral iron supplements, and 2)…
- Trial name
- NCT03572010
- Testing
- FeFum fortified maize test meal, FeSO4 fortified LNS, FeSO4 supplement
- Where
- South Africa
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy Volunteer
Cell Tracking Using Superparamagnetic Particles of Iron Oxide (SPIO) and Magnetic Resonance Imaging (MRI) - A Pilot Study
The ability to label specific cells and image their natural movements in vivo would allow researchers to investigate the mechanisms of disease progression.
- Trial name
- NCT00972946
- Testing
- Administration of autologous Endorem-labelled mononuclear cells intravenously, Administration of Endorem
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Low Birth Weight, Perinatology
Effect of Delayed Cord Clamping on Haematological Status in Low Birth Weight Infants
Delayed cord clamping (DCC, clamping after cessation of pulsations in the cord around 2-3 min after delivery) is effective in increasing (low birth weight) infant haemoglobin and iron status until six months after birth, without…
- Conditions
- Low Birth Weight, Perinatology, Iron Status, Cord Clamping
- Trial name
- NCT01487980
- Testing
- Cord clamping
- Where
- South Africa
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Stanger Hospital
Anemia, Iron-deficiency
Optimizing Iron Status While Minimizing Morbidity in HIV-infected Ugandan Children
Randomized, placebo-controlled trial of the effect of 84 days of daily iron supplementation on iron status, gut microbiome profile, infectious disease frequency, and HIV disease severity in moderately anemic [hemoglobin 9 - <11…
- Conditions
- Anemia, Iron-deficiency, Iron Deficiency Anemia, Hiv
- Trial name
- NCT03596996
- Testing
- Ferrous Sulfate
- Where
- Uganda
- Volunteers
- 200 people
- Sponsor
- University of Minnesota
Iron Metabolism Disorders
Iron Status in Women of Reproductive Age Reproductive Age
Analyzed iron status, HFE mutations and ethnicity for women in five primary care centers in the United States and Canada using de-identified data from the HEIRS study.
- Trial name
- NCT03276247
- Testing
- observation
- Where
- United States
- Volunteers
- 22,042 people
- Sponsor
- Victor Gordeuk
Inflammatory Bowel Disease
Iron Oligosaccharide in Inflammatory Bowel Disease Subjects With Iron Deficiency Anaemia
The purpose of the trial is to demonstrate that intravenous iron oligosaccharide is non-inferior to oral iron sulphate in reducing iron deficiency anaemia secondary to inflammatory bowel disease (IBD), evaluated as the ability to…
- Trial name
- NCT01017614
- Testing
- Monofer, Iron Sulphate
- Where
- 10 sites in Denmark, India and 1 more
- Volunteers
- 350 people
- Sponsor
- Pharmacosmos A/S
Chronic Heart Failure
Oral Iron Repletion Effects On Oxygen Uptake in Heart Failure
The purpose of this study is to determine if oral iron (Fe) polysaccharide is superior to oral placebo in improving functional capacity as measured by change in peak VO2 (oxygen uptake) by CPET (Cardiopulmonary Exercise Testing)…
- Trial name
- IRONOUT (NCT02188784)
- Testing
- Polysaccharide Iron Complex 150 mg
- Where
- 17 sites in United States
- Volunteers
- 225 people
- Sponsor
- Adrian Hernandez