Clinical trials: Iron
Iron Deficiency
Iron Absorption From Iron-fortified Fonio Porridge: a Stable Isotope Study
The study sought to investigate the effect of lowering phytic acid in fonio porridge with phytase activity naturally occurring in wheat flour on iron absorption using labelled stable isotopes of iron.
- Trial name
- NCT01443832
- Testing
- Fe57 and Fe58-FeSO4 stable isotopes
- Where
- Benin
- Volunteers
- 16 people
- Sponsor
- Wageningen University
Iron-deficiency
Effect of Polyphenols on Absorption of Iron From Sodium Iron Chlorophyllin
Polyphenols present in tea are known to inhibit the absorption of non heme iron. The inhibiting effect of tea on non-heme iron absorption is attributed to the flavonoids present in tea.
- Trial name
- polySIC (NCT04849832)
- Testing
- SIC, SIC + tea, FeSO4
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia Treatment
Daily Versus Alternate Day Regimen of Iron Supplementation in Children with Iron Deficiency Anemia
The goal of this clinical trial is to learn if giving iron supplementation every other day is as effective as giving it daily in children with Iron Deficiency Anemia. The main questions it aims to answer are: 1.
- Trial name
- NCT06631612
- Testing
- ferric hydroxide polymaltose complex, Albendazole.
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Cardiovascular Diseases, Anemia, Iron-deficiency
Iron in Patients With Cardiovascular Disease
It is now recognized that iron deficiency in cardiovascular disease contributes to impaired clinical outcome.
- Conditions
- Cardiovascular Diseases, Anemia, Iron-deficiency, Acute Myocardial Infarction, Atrial Fibrillation
- Trial name
- iCHF-2 (NCT03991000)
- Testing
- Ferric carboxymaltose, Saline
- Where
- 3 sites in Germany
- Volunteers
- 8 people
- Sponsor
- Dr. med. Mahir Karakas
Pregnancy Related, Iron Deficiency Anemia of Pregnancy
Daily Versus Alternate Day Iron Supplementation for the Treatment of Iron Deficiency Anemia in Pregnancy
The target population for our study is pregnant women in the first or second trimester with a diagnosis of iron deficiency anemia. If a subject is eligible, written consent will be obtained by person to person contact.
- Trial name
- NCT04594070
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Anemia, Iron Deficiency Anaemia in Childbirth
Impact of Iron Supplementation During Pregnancy
During pregnancy, iron deficiency is the most common cause of anemia. Anemia is very common during pregnancy and after childbirth.
- Conditions
- Anemia, Iron Deficiency Anaemia in Childbirth, Pregnancy
- Trial name
- NCT07814378
- Testing
- Iron
- Where
- 2 sites in Germany
- Volunteers
- 800 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Anemia, Leukemia
Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer
RATIONALE: Darbepoetin alfa may cause the body to make more red blood cells. Red blood cells contain iron that is needed to carry oxygen to the tissues.
- Conditions
- Anemia, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00661999
- Testing
- darbepoetin alfa, ferrous sulfate, sodium ferric gluconate complex in sucrose
- Where
- 2 sites in United States
- Volunteers
- 502 people
- Sponsor
- Mayo Clinic
Autoimmune Gastritis
Exploratory Study on the Efficacy of Betaine Hydrochloride in Treating Autoimmune Gastritis
Autoimmune gastritis (AIG) is a chronic autoimmune disorder characterized by parietal cell destruction and oxyntic mucosal atrophy, leading to achlorhydria and intrinsic factor deficiency.
- Trial name
- NCT06881511
- Testing
- No intervention (Control Group), Oral betaine hydrochloride (2 capsules, 3 times daily)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Iron Deficiency, Biofortification
Iron Absorption From Regular, Biofortified and Post-harvest Fortified Pearl Millet
Iron deficiency (ID) with or without anemia is still a main public health problem in sub-Saharan Africa and Southern Asia, especially in vulnerable population groups such as children below 5 years of age and women of reproductive…
- Trial name
- NCT01634932
- Testing
- Regular iron, Iron biofortified millet, Post-harvest iron-fortifed millet
- Where
- Benin
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Physical Exercise, Time Restricted Eating
Effect of Time-restricted Eating and Endurance Training on Markers of the Health of Women and Men
The aim of this project is to demonstrate the synergistic effect of TRE and NW training on health indicators for older women. The women will be divided into four groups, i.e.
- Conditions
- Physical Exercise, Time Restricted Eating, Mental Health Wellness 1, Wellbeing
- Trial name
- NCT05229835
- Testing
- Time restricted eating and exercise
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Transfusional Iron Overload
Active Drug Surveillance Program of Ferriprox Use
Observational, open label, prospective, multi-center, post-marketing drug surveillance program.
- Trial name
- NCT01838291
- Where
- 14 sites in Cyprus, Egypt and 3 more
- Volunteers
- 294 people
- Sponsor
- ApoPharma
Fatigue, Iron Deficiency
Clinical Evaluation of Iron Treatment Efficiency Among Non-anemic But Iron-deficient Female Blood Donors
The purpose of this study is to determine the subjective response of iron substitution (Tardyferon®) on fatigue in women blood donors with a mean serum ferritin < 30ng/ml and to assess variation of ferritin and hemoglobin after a…
- Trial name
- ferdon (NCT00689793)
- Testing
- Ferrous sulphate
- Where
- Switzerland
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Hypophosphatemia, Chronic Kidney Diseases
Investigation of Hypophosphataemia Following Intravenous Iron
Anaemia (low haemoglobin levels) can develop in a number of conditions, including chronic kidney disease (CKD) and intestinal conditions (e.g. inflammatory bowel disease, intestinal failure).
- Conditions
- Hypophosphatemia, Chronic Kidney Diseases, Intestinal Disease, Anemia
- Trial name
- NCT04502784
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Very Low Birth Weight Infant, Premature Infants
Pilot Trial Investigating Every Other Day Dosing of Oral Iron in Premature Infants (IQONic)
Study focuses on determining if daily versus every-other-day (EOD) oral iron at the same dose per kilogram per day will achieve similar incidence of iron replete status at 36 weeks post-menstrual age in premature neonates
- Conditions
- Very Low Birth Weight Infant, Premature Infants, Anemia of Prematurity, Iron Deficiency, Anaemia in Children
- Trial name
- NCT06555315
- Testing
- 6 mg/kg of oral iron as ferrous sulfate administered every other day., 6 mg/kg of oral iron as ferrous sulfate administered every day.
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- CHRISTUS Health
Erythropoietic Protoporphyria, Iron-deficiency
Iron Therapy in Erythropoietic Protoporphyria
Giving oral iron to patients with erythropoietic protoporphyria (EPP) who is iron deficient is thought to be beneficial. This is, however, not well documented.
- Trial name
- NCT05572125
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Bispebjerg Hospital
Healing Wound, Iron-deficiency
Impact of Iron Stores on Wound Healing in Plastic Surgery
In breast reduction surgery, delayed wound healing may increase surgical site infections, cutaneous necrosis and may be related to psychological harm.Some risk factors have been identified : smoking, diabetes, overweight.
- Conditions
- Healing Wound, Iron-deficiency, Surgical Wound
- Trial name
- IRONPLAST (NCT04276168)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Iron-deficiency, Iron Deficiency Anemia
Alternate Day vs. Daily Iron Supplementation in Iron Depleted Women
Iron deficiency (ID) with or without anemia is a major public health problem worldwide, especially in women of reproductive age.
- Trial name
- NCT05105438
- Testing
- Consecutive Day Dosing, Alternate Day Dosing
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Non-Alcoholic Fatty Liver Disease, Diabetes Mellitus
Iron Depletion Therapy for Type 2 DM and NAFLD
The purpose of this study is to find out whether lowering the amount of iron in the body will result in less resistance to insulin and improved liver function in patients with type 2 diabetes mellitus and non-alcoholic fatty…
- Trial name
- NCT00230087
- Testing
- blood donation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Anemia
IV Iron Safety: Evaluation of Iron Species in Healthy Subjects
An approved treatment for anemia or low blood count due to chronic kidney disease is IV (intravenous, given into the vein) injection of an iron treatment. IV iron increases iron in the blood.
- Trial name
- NCT02399449
- Testing
- Brand sodium ferric gluconate, Generic sodium ferric gluconate
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Postural Orthostatic Tachycardia Syndrome
Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS)
This study is designed to investigate whether the treatment of non-anemic iron deficiency with intervenous iron sucrose will result in decreased symptom reporting and improved cardiovascular indices in adolescents (age 12-21)…
- Trial name
- NCT01978535
- Testing
- Iron infusion, Normal saline infusion
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic