Clinical trials: Iron Bioavailability
Iron-deficiency, Absorption; Iron
Iron Absorption From Iron-enriched Aspergillus Oryzae
Ferrous sulfate is rapidly absorbed and the bolus of iron enters blood rather quickly possibly leading to higher concentrations of non-transferrin bound iron which induces oxidative stress.
- Conditions
- Iron-deficiency, Absorption; Iron, Anemia, Iron Deficiency, Bioavailability
- Trial name
- BIEFS (NCT03156712)
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Iron Absorption
Iron Absorption From Iron Enriched Aspergillus Oryzae in Females Using Stable Isotope Methodology
The objective of this study was to compare the iron absorption from ferric pyrophosphate enriched Aspergillus oryzae (ASP-p) to commonly used ferric pyrophosphate (FePP) and ferrous sulfate (FeSO4) when fortified in chicken…
- Trial name
- NCT03586245
- Testing
- Ferric pyrophosphate, Aspiron, Ferrous sulfate
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Iron Absorption, Iron Deficiencies
Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya
Reports from the Kenya Red Cross Society (KRCS) in Kwale County, southern Kenya, indicate a limited impact of Ready-to-Use Therapeutic Foods (RUTFs) on malnutrition or anemia.
- Conditions
- Iron Absorption, Iron Deficiencies, Severly Acutely Malnourished Children, Malnutrition in Children
- Trial name
- SAMI (NCT07315295)
- Testing
- Iron absorption from RUTF on Day 0, Treatment with RUTF for 80 days, Iron absorption from RUTF on Day 20
- Where
- 2 sites in Kenya, Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Iron-deficiency
Effect of Polyphenols on Iron Absorption From Finger Millet
In India, one of the fast growing countries, 53% of all women have anaemia as per the National Family Health Survey. A recently published study on the burden of disease in India concluded that the burden of Iron deficiency…
- Trial name
- NCT04194567
- Testing
- Black Ragi, White Ragi
- Where
- 2 sites in Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency (Without Anemia)
Absorption of Iron From Stabilized Lactoferrin: A Study in Women With Iron Deficiency
Lactoferrin (LF) is a natural iron-binding protein found in milk. It exists either in an iron-free state (apo-LF) or bound to iron (holo-LF).
- Trial name
- LOBSTER (NCT07394972)
- Testing
- FeSO4 + meal-matrix, FeSO4 + native LF + meal-matrix, FeSO4 + NaCas-LF + meal-matrix
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nicole Stoffel
Evaluation of Bioavailability of Supplemental Forms of Iron
Glycoprotein Matrix-Bound Iron Improves Iron Absorption
A double-blind, randomized crossover study was conducted that evaluated absorption kinetics of 3 forms of dietary supplement iron by measuring iron levels in the blood after acute ingestion.
- Trial name
- NCT06738199
- Testing
- dietary iron supplementation
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Mary Hardin-Baylor
Generally Healthy
The Effect of a Short Term Exercise Schedule on Oral Iron Bio-availability and Iron Incorporation
Iron metabolism may undergo changes during exercise, with reductions in classical iron status markers due to a variety of postulated mechanism which include hemodilution, increased iron loss, hemolysis and increased iron storage…
- Trial name
- NCT01730521
- Testing
- Exercise (Running)
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy, Iron Deficiency
Bioavailability of Iron From Savoury Food Product
The study is designed to assess the bioavailability of iron from 4 different iron fortified savoury food products
- Trial name
- NCT02280915
- Testing
- Savoury food product
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Unilever R&D
Nutritional Deficiency
Zinc and Iron Bioavailability From Biofortified Pearl Millet
Populations who consume non-fortified plant-based diets are at increased risk of iron and zinc deficiencies. The purpose of this randomized controlled study is to determine the absorption of iron and zinc from pearl millet…
- Trial name
- NCT01783067
- Testing
- Pearl millet, Biofortified pearl millet
- Where
- 2 sites in United States, India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Iron Deficiency Anaemia
A Pilot Study to Assess the Influence of Dietary Organic Acids on Iron Absorption.
Iron deficiency is the most common micronutrient deficiency in the world today, affecting more than 60% of the global population (www.who.int/nut/ida.htm).
- Trial name
- NCT01991600
- Testing
- ferrous sulphate, ferric iron oxide-organic acid (Fe-OA)
- Where
- United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Medical Research Council
Iron-deficiency
Measuring Dietary Iron Absorption From Edible Insects and Assessing the Effect of Chitin Content on Iron Bioavailability (Study 1)
Due to the growing world population, there is a need to develop viable ecological and nutritional alternatives to animal food products.
- Trial name
- Sustironable1 (NCT04510831)
- Testing
- Refined maize with extrinsic addition of labelled FeSO4, T.molitor native chitin, T molitor reduced chitin
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency, Anemia
Using Stable Iron Isotopic Techniques and Serum Hepcidin Profiles to Optimize Iron Supplementation
Oral iron supplementation (OIS) is a widely-used strategy to treat iron deficiency anemia. However, absorption of OIS is often low and response is variable.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT01785407
- Testing
- Iron Supplement (Ferrous Sulfate Dried)
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency
Iron Bioavailability of High Surface Area Ferric Phosphate
The primary objective of this study is to compare iron absorption of high surface area ferric phosphate with that of ferrous sulfate and bulk ferric phosphate in a rice-based meal in non-pregnant women.
- Trial name
- HiFe (NCT03660462)
- Testing
- FeSO4 fortified rice test meal, FePO4 fortified rice test meal, HiFePO4 1 fortified rice test meal
- Where
- Thailand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia, Anemia
Iron Fish in Dominican Republic (DR) Children
The objective of the study is to assess the acceptability, feasibility, and barriers to Lucky Iron Fish™ (LIF) utilization among families with young children in a Latin American community with a high prevalence of iron deficiency…
- Conditions
- Iron Deficiency Anemia, Anemia, Iron-deficiency
- Trial name
- NCT03199235
- Testing
- Lucky Iron Fish, enhanced standard of care
- Where
- Dominican Republic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Iron Bioavailability
Baby Iron Bioavailability Study
The overall objective of this trial is to investigate the iron bioavailability from new infant cereals in Malawian infants.
- Trial name
- NCT03754543
- Testing
- Labeled iron salt Fe54, Labeled iron salt Fe57, Labeled iron salt Fe58
- Where
- Malawi
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Iron-deficiency
Effect of Iron-fortified Pea Powder on Exercise Performance
Female endurance athletes are susceptible to iron deficiency and this can impact their exercise performance. This study assesses the impact of an pea protein supplement with high iron bio-availability on iron status and exercise…
- Trial name
- NCT04872140
- Testing
- Low phytate pea powder, Regular pea powder
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Iron Bioavailability
Regular Consumption of High Phytate Reduces Inhibitory Effect of Phytate on Iron Absorption
The purpose of this study is to investigate whether regular consumption of phytate dampens its negative effect on nonheme iron absorption.
- Trial name
- NCT02370940
- Testing
- High phytate intake, Low phytate intake
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Low Iron Stores
The Effect of Lactobacillus Cultures on Iron Bioavailability.
The purpose of this study is to determine the effect of a lactic acid fermented oat gruel on iron absorption in the upper and lower part of the intestine, respectively.
- Trial name
- NCT00283491
- Testing
- Active Lactobacillus plantarum 299v, Inactive Lactobacillus plantarum 299v
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Iron Deficiency Anemia, Iron-deficiency
Multiple Daily Condensed Tannin Supplementation and Iron Bioavailability: The Tannin Dose Response Trial
Tannins are known to inhibit iron absorption through formation of insoluble tannin-mineral complexes, and have thus been termed 'antinutritional.' Despite this, there is evidence that adaptation to similar antinutritional factors…
- Trial name
- NCT03030716
- Testing
- 95% condensed proanthocyanidins from grape seed extract
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Iron Deficiency (ID), Iron Absorption
Iron Absorption From Plant Heme Iron
Heme, an iron protoporphyin IX complex, consists of a ferrous ion captured in a porphyrin ring acting as a tetradentate ligand. The unique features of heme iron -its unusually high absorption in foods and its resistance to…
- Trial name
- PHIA (NCT07143890)
- Testing
- Iron chlorophyllin + no-matrix, SoyHb + no-matrix, FeSO4 + no-matrix
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ETH Zurich