Clinical trials: Iron Deficiencies, open to volunteers
Iron Absorption, Iron Deficiencies
Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya
Reports from the Kenya Red Cross Society (KRCS) in Kwale County, southern Kenya, indicate a limited impact of Ready-to-Use Therapeutic Foods (RUTFs) on malnutrition or anemia.
- Conditions
- Iron Absorption, Iron Deficiencies, Severly Acutely Malnourished Children, Malnutrition in Children
- Trial name
- SAMI (NCT07315295)
- Testing
- Iron absorption from RUTF on Day 0, Treatment with RUTF for 80 days, Iron absorption from RUTF on Day 20
- Where
- 2 sites in Kenya, Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Autoimmune Gastritis
Exploratory Study on the Efficacy of Betaine Hydrochloride in Treating Autoimmune Gastritis
Autoimmune gastritis (AIG) is a chronic autoimmune disorder characterized by parietal cell destruction and oxyntic mucosal atrophy, leading to achlorhydria and intrinsic factor deficiency.
- Trial name
- NCT06881511
- Testing
- No intervention (Control Group), Oral betaine hydrochloride (2 capsules, 3 times daily)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Iron Deficiency Anemia Treatment, Iron Deficiency
How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?
The goal of this clinical trial is to investigate how iron status and heavy bleeding during the menopausal transition affect women's cognitive function and quality of life.
- Conditions
- Iron Deficiency Anemia Treatment, Iron Deficiency, Iron Deficiency (Without Anemia)
- Trial name
- MENO (NCT06798584)
- Testing
- FeoSol Original Iron Supplement Tablets, 21st Century Gelatin Capsules
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Purdue University
Iron Deficiency Anemia, Pregnancy
Intravenous Versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy
Double blind, placebo controlled, multicenter randomized trial in pregnant women in the U.S. (N=300) to test the central hypothesis that IV iron in pregnant women with IDA (Hb<11 g/dL and ferritin<30 ng/mL) at 13 - 30 weeks will…
- Trial name
- IVIDA2 (NCT05462704)
- Testing
- Ferric derisomaltose, Ferrous sulfate
- Where
- 8 sites in United States
- Volunteers
- 300 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Anemia, Iron-Deficiency, Nutritional Deficiencies
Reducing Anemia Among Preconception Women in Nepal Through a Group Norm and Micronutrient Supplementation Intervention
Preconception micronutrient status (including anemia) is a critical determinant of maternal, newborn, and child health that remains undervalued in Nepal. However, providing micronutrient supplements (MMS) alone is not enough.
- Conditions
- Anemia, Iron-Deficiency, Nutritional Deficiencies, Adherence, Norms, Social
- Trial name
- Sumadhur (NCT06810440)
- Testing
- Sumadhur, Multiple micronutrient supplement MMS
- Where
- Nepal
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Breath-holding Spell
Breath-holding Spells and Its Management Study
The goal of this prospective population-based study is to evaluate the new disease description and management guidelines for breath-holding spells in children (Hellström Schmidt et al, Acta Paediatrica 2024) below the age of 5…
- Trial name
- BAM (NCT06628271)
- Testing
- Guidelines
- Where
- 12 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Iron Deficiency Anemia, Digital Health Literacy
FACE-APPS-Based Approach for Improving Iron Deficiency Anaemia Indicators Among Female Adolescents at Marginalized Communities
This study aims to evaluate the effect of the Face-to-face Assisted Counselling with Enhanced Application School-Based Approach (FACE-APPS-Based Approach) on anemia indicators among female adolescents.
- Conditions
- Iron Deficiency Anemia, Digital Health Literacy, Health Promotion Model (HPM)
- Trial name
- NCT07633262
- Testing
- FACE-APPS-Based Approach
- Where
- Saudi Arabia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Anemia
Study on Supplement of Intravenous Ferric Derisomaltose to Prevent Anemia and Improve the Quality of Life in Obese Patients With Iron Deficiency.
This study aimed to explore the effects of preoperative intravenous isomaltose iron supplementation versus placebo on postoperative Hb improvement, prevention of postoperative anemia, and improvement in quality of life in…
- Conditions
- Obesity, Anemia, Iron Deficiencies, Bariatric Surgery
- Trial name
- NCT07236788
- Testing
- Iron Isomaltoside injection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- China-Japan Friendship Hospital
Advanced Gastric Carcinoma
Efficacy and Safety oF FErric CarboxymalTose in Patients With Advanced Gastric Cancer(EFFECT-AGC)
The main objective of this study is to evaluate the efficacy and safety of IV FCM(ferric carboxymaltose) in patients with AGC receiving palliative chemotherapy.
- Trial name
- NCT05226169
- Testing
- Ferinject, Conservative management
- Where
- South Korea
- Volunteers
- 330 people
- Sponsor
- Asan Medical Center
Iron Deficiency (ID), Pregnancy
Probiotic Supplementation in Optimizing Iron and Hematological Status Among Pregnant Females
Maternal iron deficiency (ID) and iron deficiency anemia (IDA) is associated with maternal and infant mortality, spontaneous preterm birth, maternal postpartum hemorrhage, and neurocognitive defects in the neonate.
- Trial name
- ProMoms (NCT07076849)
- Testing
- Lactiplantibacillus plantarum 299v
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Iron Deficiency Anemia in Preterm Neaonates
Liposomal Iron Versus Ferrous Iron Supplementation for Early Prophylaxis of Iron Deficiency Anemia in Preterm Neonates
Iron prophylaxis will be initiated at age of 2-3 weeks at a dose of 3mg/kg/day. Standard care group: will receive ferrous iron (Enrich oral drops(50mg/ml), one drop per kilogram of body weight daily.
- Trial name
- NCT07667205
- Testing
- Daily oral ferrous ion, Daily oral liposomal iron, Oral liposomal iron every other day
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Nutritional Status, Iron-deficiency
Assessing Dietary Intake of Selected Food Components Using Short Questionnaires
The aim of the study is to validate short questionnaires for assessing dietary intake of selected food components, with a focus on dietary fibre and iron.
- Conditions
- Nutritional Status, Iron-deficiency, Diet
- Trial name
- NutriPlant/FFQ (NCT07442305)
- Testing
- 5d-PD: Nutritional intakes using 24-h food recalls, KV-PV: Dietary fibre intake, KV-Fe: Iron intake
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Iron Absorption
Dietary Iron Requirements
Dietary Reference Intakes (DRIs) for iron are based on a relatively small number of studies in European populations. This research study will determine iron needs in a representative sample of adults living in the US using the…
- Trial name
- NCT07139821
- Testing
- Stable iron isotope
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Iron Deficiency Anaemia
The Use of Robot Assisted Magnetically Controlled Capsule Endoscopy in Patients With Iron Deficiency Anaemia
In this study the investigators will recruit patients who have already had an upper gastrointestinal (GI) tract endoscopy (OGD) and lower GI tract investigations which did not identify the source of iron deficiency anaemia, and…
- Trial name
- NCT07197424
- Testing
- Robot assisted magnetically controlled capsule endoscopy
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Edinburgh
Pulmonary Hypertension, Iron Deficiency
The Impact of IV Iron on Exercise Capacity and Quality of Life in Pulmonary Hypertension
Pulmonary hypertension (PH) is a condition characterized by elevated blood pressure in the pulmonary arteries. This leads to symptoms such as shortness of breath and a significantly reduced exercise capacity, resulting in a very…
- Trial name
- IRON-PH (NCT07359599)
- Testing
- Ferric Carboxymaltose (FCM), Sodium Chloride (NaCl) 0.9 %
- Where
- 7 sites in Belgium
- Volunteers
- 306 people
- Sponsor
- Ziekenhuis Oost-Limburg
Iron Deficiency Anemia
Alternate-day Versus Daily Oral Iron Therapy in Children With Iron Deficiency Anaemia
The goal of this clinical trial is to find out whether Iron (III)-hydroxide polymaltose complex (IPC) given on an alternate-day schedule works as well as daily dosing in treating iron deficiency anaemia in children.
- Trial name
- NCT07391371
- Testing
- Alternate-day oral Iron (III)-hydroxide polymaltose complex, Iron (III)-hydroxide polymaltose complex - daily oral dosing Iron (III)-hydroxide polymaltose complex - alternate-day oral dosing
- Where
- 2 sites in Burma
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Medicine, Mandalay
Iron Deficiencies, Low Ferritin
A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females
This randomized, double-blind, active-controlled trial will evaluate the effects of human lactoferrin supplementation combined with low-dose iron on iron status, aerobic performance, and lactate metabolism in exercising women…
- Conditions
- Iron Deficiencies, Low Ferritin, Iron Deficiency, Exercise Performance of Fit Athletes
- Trial name
- EFF (NCT07546591)
- Testing
- Lactoferrin 100 mg, Lactoferrin 300 mg, Iron Supplementation (5 mg)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Iron Deficiencies
The Effects of Iron Treatment on Vaccine Immunogenicity in Kenyan Infants With Iron Deficiency
Malaria and iron deficiency cause a significant burden of disease in Africa. Iron deficiency (ID) might affect immune responses to vaccination.
- Trial name
- NCT06816524
- Testing
- Iron syrup, Multivitamin syrup, R21-Matrix/M Vaccine (malaria vaccine)
- Where
- Kenya
- Volunteers
- 324 people
- Sponsor
- Nicole Stoffel
Anemia, Iron Deficiencies
Long-term Outcomes Sub-Study of Preoperative Combined Iron Therapy
This is a sub-study of the Preoperative Combined Iron Therapy trail in which some participants will be additionally randomized to combined iron supplementation or standarded treatment control to evaluate the impact on long-term…
- Conditions
- Anemia, Iron Deficiencies, Cardiac Surgery
- Trial name
- NCT06968936
- Testing
- Sucrose Iron，subcutaneous recombinant human erythropoietin，intravenous vitamin C, Routine perioperative management
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cystic Fibrosis, Iron Deficiencies
Iron Repletion in Cystic Fibrosis
The researchers in this study hope to learn whether oral (PO) or intravenous (IV) iron treatments are better for treating iron deficiency in patients with cystic fibrosis (CF).
- Conditions
- Cystic Fibrosis, Iron Deficiencies, Iron Deficiency Diseases
- Trial name
- NCT07903311
- Testing
- IV Repletion, PO Repletion
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan