Clinical trials: Iron-Deficiency
Iron-deficiency
Cross-over Study to Evaluate the Rate and the Extent of Iron Absorption of an ODF Iron Supplement vs an Iron Supplement in Capsules
Open, monocentric, comparative, cross-over study to evaluate the rate and the extent of iron absorption after a single oral dose of (A) IBSA Iron orodispersible film vs (B) SiderAL® FORTE capsules in healthy women aged 18 to 55…
- Trial name
- NCT05660200
- Testing
- IBSA Iron ODF, SiderAL® FORTE
- Where
- Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Iron Deficiency Anemia of Pregnancy
Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia
This study aims to assess whether administering intravenous iron early in pregnancy, compared to standard oral iron treatment, can enhance hemoglobin levels before delivery and reduce the need for blood transfusions in patients…
- Trial name
- IDA (NCT06366698)
- Testing
- Venofer 200 MG Per 10 ML Injection, Ferrous sulfate
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Arrowhead Regional Medical Center
Pregnancy Related, Pregnancy Anemia
Adherence of Iron Succinylate Therapy in Pregnancy
According to the World Health Organization (WHO), anemia is the most common disease, affecting >1.5 billion people worldwide. Furthermore, iron deficiency anemia (IDA) accounts for 50% of cases of anemia.
- Conditions
- Pregnancy Related, Pregnancy Anemia, Iron Deficiency Anemia
- Trial name
- ARTEMIS (NCT03873571)
- Where
- Greece
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Heart Failure, Ventricular Tachycardia
Biomarkers in Risk Stratification of Sustainted Ventricular Tachycardia or Electrical Storm After Ablation
Prevalence of HF reaches 1-2% of developed populations, and consequently a significant problem becomes more frequent occurrence of ventricular arrhythmias (VA) - sustained ventricular tachycardia (sVT) and electrical storm (ES)…
- Conditions
- Heart Failure, Ventricular Tachycardia, Ventricular Dysfunction
- Trial name
- STORM (NCT02784912)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Anemia, Iron Deficiency
Ferritin as a Predictor for Anemia in Pregnancy
Anemia is a common problem with pregnant women around the world. There are high rates even within industrialized nations. The main cause of anemia in pregnancy is a lack of iron.
- Trial name
- NCT03565198
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- CAMC Health System
Iron-deficiency, Iron Deficiency Anemia
Iron Fish for Dominican Republic (DR) Infants
This study evaluates the feasibility of cooking with an iron ingot, Lucky Iron Fish™ (LIF), and evaluate the natural history of hemoglobins and iron status among infants of families using this iron ingot in a population with a…
- Trial name
- NCT03606993
- Testing
- Lucky Iron Fish (TM) - An iron ingot that is a Cooking supplement
- Where
- Dominican Republic
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Anemia, Iron Deficiency, Solid Tumor
Quality Assurance on Anemia Management in Patients With Solid Tumors and Malignant Lymphoma
The aim of the study is to analyze the implementation of the 2018 updated ESMO Guideline in patients with tumor diseases as well as the corre-sponding recommendations of the Onkopedia Guideline and the S3 Guide-line Supportive…
- Conditions
- Anemia, Iron Deficiency, Solid Tumor, Malignant Lymphoma
- Trial name
- QA Anemia (NCT05190263)
- Testing
- non-interventional retrospective epidemiological observational study
- Where
- Germany
- Volunteers
- 1,053 people
- Sponsor
- AIO-Studien-gGmbH
Anemia, Iron-deficiency
Efficacy Study of Multiple Micro Nutrients Supplementation
This study is initiated to investigate the effect of multi micronutrient supplementation for 12 months on serum haemoglobin level in Indonesian young children.
- Trial name
- Babytop (NCT01840384)
- Testing
- Multi-micronutrients, Maltodextrin and Lactose
- Where
- Indonesia
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- PT. Sari Husada
Celiac Disease
Effect of Intravenous Iron Supplementation on Celiac Disease Remission (IRONCEL)
The study aims is to evaluate the efficacy of intravenous iron supplementation on celiac disease remission (total intestinal mucosal recovery).
- Trial name
- IRONCEL (NCT05114278)
- Testing
- Ferinject, oral iron
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anemia During Pregnancy
Bovine Lactoferrin Versus Ferrous Sulphate In The Treatment Of Iron Deficiency Anemia During Pregnancy
130 pregnant women with Iron deficiency anemia, in the 2nd trimester (microcytic hypochromic anemia, hemoglobin range from 9-10.5g/dl, serum ferritin less than 12 ng/ml), from the outpatient clinics in the Obstetrics and…
- Trial name
- NCT03202615
- Testing
- L (lactoferrin), F (ferrous sulphate)
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Abdelwahed, Mai Mahmoud Mohamed, M.D.
Iron Deficiency Anemia
Effect of Lactoferrin Versus Intravenous Iron Sucrose in Treatment of Anemia
Iron deficiency is the most common nutritional deficiency and the most common cause of anemia. Anemia has a significant impact on the health of the fetus as well as that of the mother.
- Trial name
- NCT05921968
- Testing
- Intravenous iron sucrose, Lactoferrin
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Pulmonary Arterial Hypertension
Oral Iron Supplementation in Pulmonary Hypertension
The purpose of this study is to investigate the effects of iron supplementation in patients with pulmonary arterial hypertension and iron deficiency.
- Trial name
- NCT01446848
- Testing
- iron supplement
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- The Cleveland Clinic
Iron Deficiencies, Low Ferritin
A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females
This randomized, double-blind, active-controlled trial will evaluate the effects of human lactoferrin supplementation combined with low-dose iron on iron status, aerobic performance, and lactate metabolism in exercising women…
- Conditions
- Iron Deficiencies, Low Ferritin, Iron Deficiency, Exercise Performance of Fit Athletes
- Trial name
- EFF (NCT07546591)
- Testing
- Lactoferrin 100 mg, Lactoferrin 300 mg, Iron Supplementation (5 mg)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Hepcidin, Saliva
Assessement of Hepcidin in Saliva in Human Volunteers
Iron deficiency with or without anemia is considered the most widespread nutritional deficiency in the world. To diagnose iron deficiency anemia (hemoglobin and ferritin measurement), a venous blood sample is necessary.
- Trial name
- NCT03816813
- Testing
- blood and saliva sampling
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia
A Test of Iron Malabsorption in Patients With Iron Deficiency Anemia
The objective of the study is to develop a simple, noninvasive test for evaluation of iron absorption as a tool to determine the cause of iron deficiency anemia.
- Trial name
- NCT00399191
- Testing
- stable isotope of iron, dysprosium
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Anemia
High Dose IV Iron Plus ESA in Chemotherapy-induced Anemia
This study is a multicenter, prospective, randomized phase 3 clinical study comparing the efficacy and safety of the combination treatment of ESA and high-dose IV iron (darbepoietin alfa + ferric derisomaltose/iron isomaltoside)…
- Trial name
- NCT05768997
- Testing
- Ferric Derisomaltose Injection, Darbepoetin Alfa Injection
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- Hallym University Medical Center
Anemia, Iron Deficiency Anaemia in Childbirth
Impact of Iron Supplementation During Pregnancy
During pregnancy, iron deficiency is the most common cause of anemia. Anemia is very common during pregnancy and after childbirth.
- Conditions
- Anemia, Iron Deficiency Anaemia in Childbirth, Pregnancy
- Trial name
- NCT07814378
- Testing
- Iron
- Where
- 2 sites in Germany
- Volunteers
- 800 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Iron Deficiency
Iron Bioavailability From Encapsulated Ferrous Sulphate
Salt is one of the very few regularly purchased food item in all socioeconomic classes including poor remote areas with subsistence farming.
- Trial name
- NCT02353325
- Testing
- non-encapsulated FeSO4, encapsulated FeSO4, before cooking, encapsulated FeSO4, after cooking
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Pulmonary Hypertension, Iron Deficiency
The Impact of IV Iron on Exercise Capacity and Quality of Life in Pulmonary Hypertension
Pulmonary hypertension (PH) is a condition characterized by elevated blood pressure in the pulmonary arteries. This leads to symptoms such as shortness of breath and a significantly reduced exercise capacity, resulting in a very…
- Trial name
- IRON-PH (NCT07359599)
- Testing
- Ferric Carboxymaltose (FCM), Sodium Chloride (NaCl) 0.9 %
- Where
- 7 sites in Belgium
- Volunteers
- 306 people
- Sponsor
- Ziekenhuis Oost-Limburg
Iron Deficiency Anemia of Pregnancy, Iron Storage Disease
Analysis of the Effect of Iron Supplements on Iron Deficiency Anemia in Pregnancy
Subjects were tested for hemoglobin, ferritin, serum iron, transferrin saturation and reticulocyte count during routine prenatal examination at 24-26 weeks of gestation, and blood samples were taken for serum hepcidin detection…
- Trial name
- NCT05804071
- Testing
- Niferex
- Where
- China
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital