Clinical trials: Iron-Deficiency
Iron Deficiency
Helicobacter Pylori Eradication Trial to Reduce Iron Deficiency in Children
The investigators hypothesize that the Helicobacter pylori bacterium decreases iron from the stomach and that this effect of the infection can be identified among persons with iron deficiency as well as among persons with normal…
- Trial name
- HEIDC (NCT00364104)
- Testing
- Quadruple sequential Helicobacter pylori eradication + iron sulfate, Quadruple sequential Helicobacter pylori eradication therapy, Ferrous sulfate
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Heart Failure With Normal Ejection Fraction, Iron-deficiency
Iron Substitution With Ferric Carboxymaltose as Treatment Strategy for Heart Failure Patients With Preserved Ejection Fraction
This study aims to investigate the effects of treatment with intravenous ferric carboxymaltose on exercise tolerance measured as VO2peak in patients with HFpEF and iron deficiency, compared to placebo.
- Trial name
- IRON-HFpEF (NCT05477498)
- Testing
- Ferric carboxymaltose
- Sponsor
- Cantonal Hospital, Baselland
Iron Deficiency Anemia
A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects
This is a Phase 3, randomized, open-label, multicenter, study in male and female pediatric subjects (2 years to <18 years of age) with IDA, or felt by their clinician to be at risk of developing IDA.
- Trial name
- NCT03893045
- Testing
- ferumoxytol, Iron sucrose
- Where
- 15 sites in United States, Lithuania and 1 more
- Volunteers
- 75 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Hemoglobinopathies, Hemolysis
Clinical and Laboratory Investigation of Humans With Informative Iron or Erythroid Phenotypes
This study will examine blood for factors that may cause or prevent diseases involving iron or red blood cells. Iron is an important nutrient for human health that is needed to produce red blood cells.
- Conditions
- Hemoglobinopathies, Hemolysis, Iron Deficiency and Overload, Anemias
- Trial name
- NCT00102245
- Where
- United States
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Iron-deficiency
The Effect of Different Prebiotics on Iron Absorption From High Dose Iron Supplements
Iron deficiency (ID) remains the most common global nutrient deficiency, with young women at high risk. Iron supplements are first line treatment for ID but absorption is often low.
- Trial name
- NCT04194255
- Testing
- ferrous fumarate, ferrous fumarate + 15 g GOS, ferrous fumarate + 15 g FOS
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Swiss Federal Institute of Technology
Cystic Fibrosis, Iron-deficiency
Intravenous Iron in Adults With Cystic Fibrosis
This pilot interventional cohort study will examine the effects of intravenous iron in adults with cystic fibrosis and iron deficiency.
- Trial name
- NCT03632525
- Testing
- Ferric carboxymaltose
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Anemia, Iron-Deficiency, Kidney Failure, Chronic
Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients
This study compares the effect of Ferrlecit® (a form of intravenous iron) to ferrous sulfate (a form of oral iron) in treating anemia and iron deficiency in chronic kidney disease patients who are not receiving erythropoietic…
- Trial name
- NCT00224055
- Testing
- Sodium Ferric Gluconate Complex in Sucrose Injection, Ferrous sulfate tablets
- Where
- 24 sites in United States, Puerto Rico
- Volunteers
- 89 people
- Sponsor
- Watson Pharmaceuticals
Fatigue, Iron-deficiency
Effect of Iron on Cerebral Dopamine Receptor Density in Non-anaemic Premenopausal Women With Low Ferritin and Fatigue
This study investigates the effect of intravenous iron substitution in non-anaemic premenopausal women with iron deficiency on: Changes in the cerebral Dopamine (DA) receptor density after iron substitution, shown by brain PET…
- Trial name
- NCT03305705
- Testing
- Iron Carboxymaltose, Sodium chloride 0.9%
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Albina Nowak, MD
Iron Deficiency Anemia, Coronary Artery Disease
Non-Interventional Study of Ferretab® Comp. (Ferrous Fumarate + Folic Acid Prolonged-Release Capsules) Effects in Adult Patients With Iron Deficiency Anemia and Cardiovascular Disease
The goal of this observational study is to learn how well Ferretab® comp. works and how safe it is for adults with iron deficiency anemia and cardiovascular disease who are receiving treatment as part of their usual medical care.
- Conditions
- Iron Deficiency Anemia, Coronary Artery Disease, Heart Failure With Preserved Ejection Fraction (HFPEF)
- Trial name
- PROMETHEUS (NCT07753031)
- Where
- 5 sites in Russia
- Volunteers
- 389 people
- Sponsor
- Alcea
Iron-deficiency, Absorption; Iron
Iron Absorption From Iron-enriched Aspergillus Oryzae
Ferrous sulfate is rapidly absorbed and the bolus of iron enters blood rather quickly possibly leading to higher concentrations of non-transferrin bound iron which induces oxidative stress.
- Conditions
- Iron-deficiency, Absorption; Iron, Anemia, Iron Deficiency, Bioavailability
- Trial name
- BIEFS (NCT03156712)
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Iron Deficiency, Iron Deficiency Anemia
An Iron-containing Food Product for the Prevention of Diminished Iron Status in Soldiers
Military personnel face intense physical and cognitive demands. Diminished iron status affects physiologic responses to these challenges.
- Trial name
- NCT01100905
- Testing
- Iron-containing food product
- Where
- United States
- Sponsor
- United States Army Research Institute of Environmental Medicine
Obesity, Iron Deficiency Anemia
Effect of Aerobic Exercise and Diet on Anthropometric and Hematological Measurements in Obese Anemic Women
Obesity and iron deficiency (ID) are two forms of the most usual nutritional disorders worldwide. Iron deficiency remains the most common nutritional deficiency and cause of anemia worldwide.
- Trial name
- NCT05165680
- Testing
- combination of aerobic exercise and healthy diet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Iron-deficiency, Microbial Colonization
Do Iron Supplements Impact the Gut Microbiome of Women of Reproductive Age?
In this randomised controlled trial the investigators will determine whether taking iron supplements compared to placebo for 21 days alters the bacteria (microbiome) in the large intestine of non-pregnant female participants.
- Conditions
- Iron-deficiency, Microbial Colonization, Anemia
- Trial name
- NCT05033483
- Testing
- Ferrous Fumarate
- Where
- Australia
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- South Australian Health and Medical Research Institute
Anemia, Iron-Deficiency
Iron Supplementation of Marginally Low Birth Weight Infants
Iron is essential for brain development and there is a well established association between iron deficiency in infants and poor neurological development. In Sweden, about 5% of newborns have low birth weight (< 2500 g).
- Conditions
- Anemia, Iron-Deficiency, Child Behavior Disorders, Cognitive Manifestations
- Trial name
- JOHN (NCT00558454)
- Testing
- Iron
- Where
- 2 sites in Sweden
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Umeå University
Iron Deficiency, Fibromyalgia
Frequency and Impact of Iron Deficiency in Pain Clinic Patients
The goal of this study is to measure the proportion of patients who have iron deficiency and if iron deficiency is treated what is the outcome.
- Trial name
- NCT06665516
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- McMaster University
Anemia, Iron Deficiency
Serum Hepcidin Immunoassay - Laboratory to Marketplace
This is a single center, prospective, observational study to demonstrate the clinical validity of the Intrinsic LifeSciences (ILS) Intrinsic Hepcidin IDx™ Test in the diagnosis and management of iron deficiency (ID) in…
- Trial name
- NCT03310736
- Testing
- Intrinsic Hepcidin IDx™ Test
- Where
- United States
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Intrinsic LifeSciences, LLC
Anemia, Iron-Deficiency
Preoperative Supplementation of Sucrosomal Iron as Hematopoietic Support.
To prove, if preoperative elective anemic patients improve their hemoglobin levels within 3-6 weeks preoperativly after daily oral dietary supplementation of 60mg sucrosomal iron.
- Trial name
- Preop Iron (NCT04351607)
- Testing
- Oleovital® Eisen Forte
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Mein Hanusch-Krankenhaus
Iron-Refractory Iron-Deficiency Anemia
Triferic IRIDA (Iron-Refractory Iron-Deficiency Anemia) Protocol
The main purpose is to determine whether Triferic, administered orally with Shohl's solution, is safe and effective for the treatment of iron-refractory iron-deficiency anemia (IRIDA).
- Trial name
- NCT02905981
- Testing
- Fer-In-Sol, Shohl's solution, Triferic
- Volunteers
- 1 people
- Sponsor
- Rockwell Medical Technologies, Inc.
Allergy Pollen, Healthy
Iron and Pollen Allergy in Women
Iron deficiency and anemia are clearly associated with the onset of allergy and allergic diseases, whereas an improved iron status seems to prevent the onset of allergy in humans. Iron-deficiency can be absolute or functional.
- Trial name
- NCT03816800
- Testing
- ImmunoBon
- Where
- Austria
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Latent Iron Deficiency
Interest of Biofer ® Compound Used in Blédilait Follow on Milk in Infant With Latent Iron Deficiency
The primary purpose of the study is to demonstrate the superiority of Bledilait milk (Biofer® 2mg/100kcal) in comparison with ferrous sulphate supplemented milk (2 mg/100 kcal) in infants (6 to 12 months) with latent iron…
- Trial name
- NCT00554814
- Testing
- Bledilait Biofer®, Milk supplemented with ferrous sulphate, Blédilait Biofer®
- Where
- France
- Volunteers
- 249 people
- Sponsor
- Bledina