Clinical trials: Iron-Deficiency
Diagnostic Errors
Reducing Diagnostic Errors in Primary Care Pediatrics (Project RedDE)
The proposal will focus on 3 specific, high-risk, pediatric ambulatory diagnostic errors each representing a unique dimension of diagnostic assessment: evaluation of symptoms, evaluation of signs and follow-up of diagnostic…
- Trial name
- NCT02798354
- Testing
- Quality Improvement Collaborative
- Where
- United States
- Volunteers
- 13,853 people
- Sponsor
- Montefiore Medical Center
Pregnancy Related, Iron Deficiency Anemia of Pregnancy
Daily Versus Alternate Day Iron Supplementation for the Treatment of Iron Deficiency Anemia in Pregnancy
The target population for our study is pregnant women in the first or second trimester with a diagnosis of iron deficiency anemia. If a subject is eligible, written consent will be obtained by person to person contact.
- Trial name
- NCT04594070
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Anemia
Study to Assess Feasibility and Safety of Iron Repletion With Feraheme in Iron Deficient Patients With Durable Ventricular Assist Device Support
Ferumoxytol injection (Feraheme®) is a parenteral form of iron supplementation that is FDA-approved for treatment of iron deficiency anemia.
- Trial name
- AMAGFeraheme (NCT04080908)
- Testing
- Ferumoxytol injection
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
Iron Deficiency Anemia of Pregnancy, Iron Malabsorption
Intravenous Iron for Iron-deficiency Anemia in Pregnancy: a Randomized Controlled Trial
Iron deficiency is the most common cause of anemia in pregnancy worldwide, and, when severe, can have serious consequences for mothers and babies.
- Trial name
- IVIDA (NCT03438227)
- Testing
- Iron dextran, Ferrous sulfate 325mg
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Indiana University
Anemia, Iron-Deficiency, Kidney Failure, Chronic
Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Receiving Erythropoietic Agents
This study compares the effect of Ferrlecit® (a form of intravenous iron) to ferrous sulfate (a form of oral iron) in treating anemia and iron deficiency in chronic kidney disease patients who are receiving erythropoietic agents…
- Trial name
- NCT00224042
- Testing
- Sodium Ferric Gluconate complex in sucrose, Ferrous sulfate tablets
- Where
- 24 sites in United States, Puerto Rico
- Volunteers
- 52 people
- Sponsor
- Watson Pharmaceuticals
Pulmonary Arterial Hypertension, Iron Deficiency
IV Iron Replacement for Iron Deficiency in Idiopathic Pulmonary Arterial Hypertension (IPAH) Patients
This study will establish whether intravenous iron replacement has clinical benefit in idiopathic pulmonary arterial hypertension.
- Trial name
- NCT01447628
- Testing
- Saline, Ferinject or CosmoFer
- Where
- 5 sites in China, Germany and 1 more
- Volunteers
- 56 people
- Sponsor
- Imperial College London
Iron Deficiency Anemia
A Trial Comparing Ferumoxytol With Iron Sucrose for the Treatment of Iron Deficiency Anemia
The purpose of the study is to evaluate the efficacy and safety of intravenous (IV) ferumoxytol compared to IV iron sucrose for the treatment of iron deficiency anemia (IDA).
- Trial name
- NCT01114204
- Testing
- Ferumoxytol, Iron Sucrose
- Where
- 96 sites in Australia, France and 12 more
- Volunteers
- 605 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Non-anemic Iron Deficiency
Iron Treatment for Young Children With Non-anemic Iron Deficiency
The pre-school years are critical years for children to acquire early learning skills such as language, fine motor and social skills; this is termed early child development.
- Trial name
- OptEC (NCT01481766)
- Testing
- Ferrous Sulfate, Dietary counseling
- Where
- 2 sites in Canada
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Haematopoiesis
A Study to Demonstrate the Efficacy and Tolerability of Ferrous Bisglycinate Chelate in Iron Deficiency Anaemia and to Compare These With Those of Ferrous Ascorbate.
Iron deficiency anaemia (Haemoglobin, Hb < 12gm/dl) is one of India's major public health problems particularly in women. Effective control of iron deficiency anaemia decreases the incidence of fatigue, bodyache, headache, lack…
- Trial name
- NCT01160198
- Testing
- ferrous ascorbate, ferrous bisglycinate chelate 1 OD, ferrous bisglycinate chelate 2 OD
- Where
- 7 sites in India
- Volunteers
- 271 people
- Sponsor
- GlaxoSmithKline
Anemia, Iron-Deficiency, Kidney Failure, Chronic
Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients
This study compares the effect of Ferrlecit® (a form of intravenous iron) to ferrous sulfate (a form of oral iron) in treating anemia and iron deficiency in chronic kidney disease patients who are not receiving erythropoietic…
- Trial name
- NCT00224055
- Testing
- Sodium Ferric Gluconate Complex in Sucrose Injection, Ferrous sulfate tablets
- Where
- 24 sites in United States, Puerto Rico
- Volunteers
- 89 people
- Sponsor
- Watson Pharmaceuticals
Iron-Refractory Iron-Deficiency Anemia
Triferic IRIDA (Iron-Refractory Iron-Deficiency Anemia) Protocol
The main purpose is to determine whether Triferic, administered orally with Shohl's solution, is safe and effective for the treatment of iron-refractory iron-deficiency anemia (IRIDA).
- Trial name
- NCT02905981
- Testing
- Fer-In-Sol, Shohl's solution, Triferic
- Volunteers
- 1 people
- Sponsor
- Rockwell Medical Technologies, Inc.
Iron Deficiency
Donor Iron Deficiency Study - Red Blood Cells From Iron-deficient Donors: Recovery and Storage Quality
Primary Hypothesis The 24-hour post-transfusion RBC recovery of units obtained from donors exhibiting iron-deficient erythropoiesis will not meet FDA standards for clinical use.
- Trial name
- DIDS (NCT02889133)
- Testing
- Iron-dextran, Saline, Blood Donation
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Columbia University
Iron Deficiency Anaemia, Iron Deficiency Anemia
Incidence of Hypophosphatemia After Treatment With Iron Isomaltoside/Ferric Derisomaltose or Ferric Carboxymaltose in Subjects With Iron Deficiency Anaemia
The trial was designed to evaluate the incidence of unintended hypophosphatemia (low level of phosphate in the blood) in subjects with iron deficiency anaemia (IDA).
- Trial name
- NCT03237065
- Testing
- Iron isomaltoside/ferric derisomaltose, Ferric carboxymaltose
- Where
- 15 sites in United States
- Volunteers
- 122 people
- Sponsor
- Pharmacosmos A/S
Myocardial Infarction, Iron-deficiency
An Open Study on the Efficacy of Iron Therapy Using iv Iron Relative to Oral Iron for Increasing LV Systolic Function
The OPERA-MI trial evaluates the effect of i.v. ferric carboxymaltose compared to the effect of oral iron, on left ventricular systolic function.
- Trial name
- OPERA-MI (NCT05309499)
- Testing
- ferric carboxymaltose, ferrous sulphate
- Where
- Russia
- Volunteers
- 298 people
- Sponsor
- Kazan State Medical University
Anemia, Pregnancy Complications
Intravenous Versus Oral Iron in Late Pregnancy: Results of Treatment
The purpose of this study is to compare the efficacy of body iron storage replenishment between low dose intravenous iron and oral iron in late pregnancy.
- Trial name
- EIVF (NCT00746551)
- Testing
- Ferli-6® (Continental Pharm co., ltd.), Venofer® (Vifor AG, St. Gallen, Switzerland)
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Heart Failure, Iron-deficiency
Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency / and Sub-Study
The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo in the treatment of participants in heart failure with a reduced…
- Trial name
- HEART-FID (NCT03037931)
- Testing
- Ferric Carboxymaltose
- Where
- 345 sites in United States, Australia and 11 more
- Volunteers
- 3,065 people
- Sponsor
- American Regent, Inc.
Iron-deficiency, Pregnancy Anemia
Feasibility or Oral Lactoferrin to Prevent Iron Deficiency Anemia in Obese Pregnancy
Maternal iron deficiency anemia is associated with maternal and infant mortality, spontaneous preterm birth, maternal postpartum hemorrhage, and neurocognitive defects in the neonate.
- Conditions
- Iron-deficiency, Pregnancy Anemia, Obesity
- Trial name
- NCT04810546
- Testing
- Jarrow Formulas Oral Bovine Lactoferrin Supplement
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Restless Legs Syndrome (RLS)
Randomized, Placebo-controlled Trial of Ferric Carboxymaltose in RLS Patients With Iron-deficiency Anemia
Treatment Phase I and II Primary Objective: To evaluate the efficacy and safety of FCM (750 mg dose x 2) for treatment of Restless Legs Syndrome (RLS) in patients with iron-deficiency anemia (IDA).
- Trial name
- NCT02826681
- Testing
- Injectafer® (Ferric Carboxymaltose - FCM)
- Where
- 8 sites in United States
- Volunteers
- 70 people
- Sponsor
- American Regent, Inc.
Postural Orthostatic Tachycardia Syndrome
Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS)
This study is designed to investigate whether the treatment of non-anemic iron deficiency with intervenous iron sucrose will result in decreased symptom reporting and improved cardiovascular indices in adolescents (age 12-21)…
- Trial name
- NCT01978535
- Testing
- Iron infusion, Normal saline infusion
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Iron-deficiency
Prebiotic GOS and Lactoferrin With Iron Supplements
The ultimate goal of this research is to develop a means to safely administer iron supplements to infants in settings with a high infection burden.
- Trial name
- NCT03866837
- Testing
- Galacto-oligosaccharides, Bovine lactoferrin, Multiple micronutrient powders with 5 mg iron
- Where
- 2 sites in Kenya, Switzerland
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Columbia University