Clinical trials: Irreversible Pulpitis
Symptomatic Irreversible Pulpitis, Apical Periodontitis
Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator
Patients with painful molars will be randomly assigned to 2 different groups: GentleWave and EndoActivator. The root canals will be completed using identical protocols except in the mode of delivery and activation of irrigation…
- Trial name
- NCT04552132
- Testing
- Multisonic vs Sonic activation of irrigants
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Symptomatic Irreversible Pulpitis (SIP)
Clinical and Radiographic Evaluation of Laser Assisted Pulpotomy in Immature Permanent Molars With Symptoms Indicative of Irreversible Pulpitis
The goal of this clinical trial is to assess the clinical and radiographic success rate of Laser pulpotomy procedure done in immature permanent molars with symptoms indicative of irreversible pulpitis..
- Trial name
- NCT07704463
- Testing
- Application of 660 nm diode laser, Application of 970 nm diode laser + MTA, Conventional MTA pulpotomy (control group)
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Alexandria University
Root Canal Sealers, Post Operative Pain
Evaluation of Post Obturation Pain Associated With Calcium Hydroxide-based Root Canal Sealers and Resin-based Root Canal Sealer: a Single Visit Root Canal Treatment
The objective of this study is to evaluate the post obturation pain associated with calcium hydroxide-based root canal sealer and resin-based root canal sealer after single visit root canal treatment following endodontic…
- Conditions
- Root Canal Sealers, Post Operative Pain, Irreversible Pulpitis
- Trial name
- NCT06798467
- Testing
- Endodontic sealer, post obturation pain
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jinnah Sindh Medical University
Post Operative Pain, Acute, Irreversible Pulpitis
To Evaluate Post Operative Pain Using Two Different Kind of Sealers in Obturation of Teeth With Symptomatic Irreversible Pulpitis During Second Visit When the Patient is Painless
The goal of this randomized clinical trial is to evaluate pain after root canal treatment using two different kinds of sealers during obturation in 60 healthy , male and female patients ages between 18 to 40 years.
- Trial name
- NCT07266974
- Testing
- AH-Plus Epoxy Resin Sealer, bioceramic sealer
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jaweria Gul Keyani
Local Anesthesia
Success of Inferior Alveolar Nerve Block in Women Taking Selective Serotonin Reuptake Inhibitors
To evaluate the success of inferior alveolar nerve block (IANB) for mandibular molars with irreversible pulpitis in women under treatment with selective serotonin reuptake inhibitors (SSRIs).
- Trial name
- NCT02884596
- Testing
- selective serotonin reuptake inhibitor
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Isfahan University of Medical Sciences
Pulpectomy, Irreversible Pulpitis
Clinical and Radiographic Outcomes of Rotary Instrumentation in Primary Molars
This study will evaluate the clinical and radiographic outcomes of rotary versus manual pulpectomy in children with irreversible pulpitis.A single-visit pulpectomy will be performed for all patients.
- Trial name
- NCT07319741
- Testing
- Rotary Instrumentation, Manual Instrumentation
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Anfal mohamed elmotaz almogtaba
Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life
Effects of Different Root Canal Filling Materials and Irrigation Agitation Techniques on Postoperative Pain in Teeth With Irreversible Pulpitis: A Randomized Clinical Trial
This clinical study is designed to evaluate the effects of different irrigation agitation techniques and root canal sealers on postoperative pain and oral health-related quality of life in patients with symptomatic irreversible…
- Conditions
- Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life, Symptomatic Irreversible Pulpitis, Endodontic Treatment
- Trial name
- NCT07859384
- Testing
- XP-Endo Finisher, EDDY, Passive Ultrasonic Activation
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Ankara University
Dental Anxiety, Symptomatic Irreversible Pulpitis
Effect of Dental Anxiety on Mandibular Anesthesia Success
The goal of this clinical trial is to evaluate the effect of dental anxiety on the success of mandibular anesthesia in patients with symptomatic irreversible pulpitis in mandibular molar teeth.
- Trial name
- NCT07124273
- Testing
- Standardized Mandibular Anesthesia Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Kutahya Health Sciences University
Pain Assessment, Quality of Life (QOL)
Supplemental Postoperative Bupivacaine Following Non-Surgical Endodontic Treatment
The study will investigate the impact of an additional injection of long-acting anesthetic on pain level, quality of life, and use of pain medication after a nonsurgical endodontic treatment.
- Conditions
- Pain Assessment, Quality of Life (QOL), Analgesic Use
- Trial name
- NCT06655454
- Testing
- Supplemental Postoperative Bupivacaine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- New York University
Pulpitis - Irreversible
Enhancing Anaesthetic Success in Mandibular Molars With Symptomatic Irreversible Pulpitis: A Comparative Randomized Controlled Trial
The goal of this clinical trial is to assess the effect of Preoperative intraligamentary corticosteroids injection Cryotherapy which is cold application on : Hard tooth structure ( crown of the tooth ) Soft tissue overlying roots…
- Trial name
- NCT06330519
- Testing
- Dexamethasone sodium phosphate injection, 1,1,1,2 tetrafluoroethane, intraoral soft tissue cryotherapy
- Where
- Egypt
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Overcoming the Failure of Anesthesia in the Mandibular Teeth
How Successful is Supplemental Intraseptal Anaesthesia in Patients With Mandibular Teeth Extraction or Irreversible Pulpitis
Introduction: Local anesthetic failure is an unavoidable aspect of dental practice. A number of factors contribute to this, which may be related to either the patient or the operator.
- Trial name
- NCT03880409
- Testing
- 2% lidocaine with 1:000,000 epinephrine, 4% articaine with 1:000,000 epinephrine
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taibah University
Symptomatic Irreversible Pulpitis (SIP)
Effect of Preoperative Diclofenac Potassium Dose on Endodontic Pain
The aim of this study is to assess the effect of different doses of diclofenac potassium premedication (100mg vs 50mg) on anesthetic success of 4% articaine buccal infiltration and post-operative pain as compared to placebo in…
- Trial name
- NCT07743372
- Testing
- Diclofenac potassium 100mg, Diclofenac potassium 50mg
- Volunteers
- 90 people
- Sponsor
- Cairo University
Irreversible Pulpitis
Post Operative Pain and Oral Health Related Quality of Life Following Pulpotomy VS Extraction of Permanent First Molar
The goal of this clinical trial is to compare between post operative pain and oral health related quality of life in participants receiving two treatments for first permanent mandibular molars with poor prognosis.
- Trial name
- NCT06420583
- Testing
- MTA pulpotomy, Extraction
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Comparative Evaluation of Partial and Complete Pulpotomy in Permanent Molars
This study will compare the outcome of partial pulpotomy and complete pulpotomy in mature permanent molars with clinical signs indicative of irreversible pulpitis
- Trial name
- NCT04397315
- Testing
- Pulpotomy to the level of canal orifices, Pulpotomy up to superficial 2-3 mm of pulp chamber
- Where
- India
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pain, Postoperative
Comparison of Efficacy of Naproxen Versus Ibuprofen
Comparison between Naproxen and Ibuprofen in management of post operative endodontic pain was done.Total 116 patients were selected and divided in to two groups.One group was given Naproxen and other was given Ibuprofen.
- Trial name
- NCT04947566
- Testing
- Comparison of Efficacy of Naproxen versus Ibuprofen
- Where
- 2 sites in Pakistan
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Irreversible Pulpitis, Deep Caries
TheraCal LC Coronal Pulpotomy and MTA Coronal Pulpotomy in Mature Permanent Molars
To evaluate and compare the clinical and radiographic success rate of TheraCal LC and MTA for coronal pulpotomy of mature permanent molar in 9-14 year children.
- Trial name
- NCT05733468
- Testing
- Theracal LC, MTA
- Where
- India
- Volunteers
- 72 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pain, Postoperative
Ibuprofen Versus Ibuprofen/Acetaminophen Postoperatively in Patients Needing Root Canal Therapy
Aim: The purpose of this study was to compare ibuprofen versus an ibuprofen/acetaminophen combination for postoperative pain control in patients requiring root canal treatment with a tooth that is painful to cold and biting.
- Trial name
- NCT03631433
- Testing
- Ibuprofen 600 mg, ibuprofen 600 mg and acetaminophen 650 mg
- Volunteers
- 102 people
- Sponsor
- Ohio State University
Irreversible Pulpitis
Effect of Addition of Mannitol to Bupivacaine on IANB Success and Post-endodontic Pain
Inferior alveolar nerve block using either 0.5% bupivacaine alone or in addittion to mannitol in patients with irreversible pulpitis in mandibular molars.
- Trial name
- NCT03749408
- Testing
- bupivacaine plus mannitol, bupivacaine alone
- Volunteers
- 60 people
- Sponsor
- Cairo University
Asymptomatic Irreversible Pulpitis
Effect of Apical Third Enlargement to Different Taper and Master Apical Preparation Size on Periapical Healing and Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment
To Determine Effect Of Apical Third enlargement To Different Taper And Master Apical Preparation Size On Periapical Healing And Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment : A Randomized…
- Trial name
- NCT07166679
- Testing
- root canal treatment with 2% taper, root canal treatment with 4% taper, root canal treatment with 6 %taper
- Where
- India
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Irreversible Pulpitis
Post Operative Pain Following Pulpectomy Versus Pulpotomy in Primary Molars Wit Irreversible Pulpitis
Study will evaluate and compare post operative pain for primary molars with irreversible pulpitis after pulpotomy and pulpuectomy
- Trial name
- NCT06903013
- Testing
- Non vitalPulp therapy, Vital pulp therapy
- Volunteers
- 50 people
- Sponsor
- Minia University