Clinical trials: Irritable Bowel Syndrome With Constipation
Irritable Bowel Syndrome With Constipation
Effect of Tai Chi as Treatment for IBS-C
The purpose of the study is to evaluate the efficacy of Tai Chi practice in reducing symptoms of Irritable Bowel Syndrome with Constipation (IBS-C).
- Trial name
- NCT04132804
- Testing
- Tai Chi
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Massachusetts General Hospital
Functional Constipation, Irritable Bowel Syndrome
Colonoscopic Probiotics Infusion for Functional Gastrointestinal Disease
The purpose of this project is to study the the efficacy and safety of probiotics implantation through infusion during colonoscopy in the treatment of functional constipation and irritable bowel syndrome.
- Conditions
- Functional Constipation, Irritable Bowel Syndrome, Probiotics, Colonoscopy
- Trial name
- CPIFGD (NCT05366335)
- Testing
- Live Combined Bifidobacterium and Lactobacillus, Normal saline, Basic treatment
- Where
- China
- Volunteers
- 160 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Irritable Bowel Syndrome With Constipation (IBS-C)
Efficacy and Safety, Tolerability of GA-AT0119 in IBS-C
Irritable bowel syndrome (IBS) is a common functional bowel disorder that imposes a considerable burden on health-related quality of life (QOL) worldwide.
- Trial name
- RELAX (NCT05240521)
- Testing
- ARM A, ARM B
- Where
- 4 sites in Bulgaria
- Volunteers
- 60 people
- Sponsor
- Devintec Sagl
Irritable Bowel Syndrome
Single-center Exploratory Study of the Intestinal Microbiota in Patients Treated for Irritable Bowel Syndrome With Predominant Constipation and Methane Production
Irritable Bowel Syndrome (IBS), characterized by the Rome IV criteria, is a functional bowel disorder combining abdominal pain with changes in bowel habits and/or stool consistency.
- Trial name
- METHANOBIOTE (NCT06801184)
- Testing
- Plasma Sample, Stool Sample
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Irritable Bowel Syndrome With Constipation
Efficacy and Safety of SYN-010 in IBS-C
Irritable bowel syndrome (IBS) is a gastrointestinal (GI) syndrome characterized by chronic abdominal pain and altered bowel habits in the absence of any organic cause.
- Trial name
- NCT03763175
- Testing
- SYN-010 21 mg, SYN-010 42 mg
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Cedars-Sinai Medical Center
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea
Personalized Dietary Intervention Based on Microbiome Analysis vs FODMAP Diet for Irritable Bowel Syndrome
irritable bowel syndrome (IBS) is a well-known risk factor for diseases of the anal region (hemorrhoids, anal fissures, etc.) and large intestine (colon cancer, diverticular disease).
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Constipation, Irritable Bowel Syndrome Mixed
- Trial name
- NCT05646186
- Testing
- Personalized dietary intervention based on microbiome analysis, Low-FODMAP diet
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Medipol University Hospital
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea
Efficacy and Safety of a Food Supplement With Standardized Menthol, Limonene, and Gingerol Content in Patients With Irritable Bowel Syndrome
The purpose of this study is to assess the efficacy and safety of a food supplement with standardized menthol, limonene, and gingerol content in patients with irritable bowel syndrome (IBS) or IBS/functional dyspepsia (FD).
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Constipation, Irritable Bowel Syndrome Mixed
- Trial name
- NCT04484467
- Testing
- Food Supplement With Standardized Menthol, Limonene, and Ginger
- Where
- Russia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Federal Stare Budgetary Scientific Institution, Mental Health Research Center
Constipation, Irritable Bowel Syndrome
Factors Affecting Dissatisfaction to Treatments in Patients With Chronic Constipation and IBS With Constipation
Chronic constipation (CC) and Irritable Bowel Syndrome with Constipation (IBS-C) are two conditions difficult to manage because factors affecting dissatisfaction to treatments are misleading.
- Trial name
- NCT02813616
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Constipation-predominant Irritable Bowel Syndrome (IBS-C)
A Study to Evaluate the Effect of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome
This study is to investigate the efficacy, safety, and plasma concentration change of ASP0456 in patients with constipation-predominant irritable bowel syndrome.
- Trial name
- NCT01714843
- Testing
- linaclotide
- Where
- 4 sites in Japan
- Volunteers
- 559 people
- Sponsor
- Astellas Pharma Inc
Irritable Bowel Syndrome Characterized by Constipation
A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
To evaluate the efficacy on abdominal symptoms (abdominal bloating, abdominal discomfort, and abdominal pain) and safety of linaclotide 290 μg administered orally to patients with IBS-C.
- Trial name
- NCT03573908
- Testing
- Linaclotide
- Where
- 79 sites in United States
- Volunteers
- 614 people
- Sponsor
- Ironwood Pharmaceuticals, Inc.
Pelvic Organ Prolapse, Constipation
Cohort Study of Bowel Function Following Robotic-assisted Laparoscopic Sacrocolpopexy
Compare changes in bowel function before, 6 months and one year after Robotic-assisted laparoscopic sacral colpopexy. Compare objective anatomic outcomes before, 6 months and one year after Robotic-assisted laparoscopic sacral…
- Conditions
- Pelvic Organ Prolapse, Constipation, Bowel Dysfunction, Irritable Bowel Syndrome
- Trial name
- NCT01618292
- Testing
- Robotic sacral colpopexy
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Atlantic Health System
Irritable Bowel Syndrome, Constipation
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated what side effects may occur, and the safety and efficacy in participants with Irritable Bowel Syndrome-Constipation (IBS-C).
- Trial name
- RENEW-IBS-C (NCT07545772)
- Testing
- LY3537031
- Where
- 70 sites in United States, Belgium and 6 more
- Volunteers
- 342 people
- Sponsor
- Eli Lilly and Company
Irritable Bowel Syndrome With Constipation (IBS-C)
4-Week, Multi-center Dose-Ranging Study for the IBS-C in Pts. 6 to <12 Yrs
This is a randomized, double-blind, placebo-controlled dose-ranging study to assess the safety and efficacy of tenapanor for treatment of the IBS-C in pediatric patients 6 to less than 12 year old.
- Trial name
- NCT06553547
- Testing
- Tenapanor
- Where
- 20 sites in United States
- Volunteers
- 72 people
- Sponsor
- Ardelyx
Rectal Hypersensitivity, Irritable Bowel Syndrome-Constipation
SAT vs Escitalopram for Rectal Hypersensitivity
Constipation is a common digestive disorder. After excluding dietary factors, drugs and other secondary causes, at least three broad pathophysiologic subtypes are recognized- dyssynergic defecation, constipation-predominant…
- Trial name
- NCT00584571
- Testing
- Sensory Adaptation Training, Escitalopram Therapy
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Augusta University
Irritable Bowel Syndrome
Open International Study on Quality of Life in Irritable Bowel Syndrome (IBS) Patients Before and After 8 Weeks Treatment With Mebeverine/Pinaverium Bromide
A study to evaluate, by country and overall, the changes from baseline of the irritable bowel syndrome quality of life (IBS QoL) total score after 4 and 8 weeks of treatment with Duspatalin® or Dicetel® in IBS patients.
- Trial name
- NCT01678781
- Where
- 24 sites in China, Egypt and 2 more
- Volunteers
- 607 people
- Sponsor
- Abbott
Irritable Bowel Syndrome, Diarrhea- Irritable Bowel Syndrome
To Study the Effect of Short-chain Fructooligosaccharides in Women With Irritable Bowel Syndrome
To evaluate whether there is clinical improvement through the scales (Bristol, IBS severity score, and IBS quality of life) in women with irritable bowel syndrome after administration of SC-FOS (short-chain…
- Conditions
- Irritable Bowel Syndrome, Diarrhea- Irritable Bowel Syndrome, Constipation-predominant Irritable Bowel Syndrome
- Trial name
- NCT05941650
- Testing
- Short Chain Fructooligosaccharides, Corn Starch
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Chihuahua