Clinical trials: Irritant Contact Dermatitis
Diaper Rash
Multicenter, National, Observational, Prospective, Real-life Study Evaluating the Performance of 2% Aqueous Eosin in Children With Diaper Rash
This study is being conducted to provide updated clinical data on safety and performance (demonstrated previously for CE marking under the Medical Devices Directive) Cooper Aqueous Eosin 2%.
- Trial name
- EA2 (NCT05599763)
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Cooperation Pharmaceutique Francaise
Diaper Rash
Clinical Study to Evaluate the Efficacy and Safety of Two Marketed Investigational Products in Children With Diaper Rash
To evaluate whether Desitin; Zinc Oxide Diaper Rash Ointment (Desitin Original) and Desitin Creamy; Zinc Oxide Diaper Rash Ointment (Desitin Creamy) provide relief of the signs and symptoms associated with diaper rash after 12…
- Trial name
- NCT00219466
- Testing
- Zinc Oxide Diaper Rash Ointment, Aloe Vera/Tocopherol/Zinc Oxide Cream
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Phototoxicity
Prevention of Phototoxicities in Patients Undergoing Vemurafenib Treatment
Vemurafenib is an anti-cancer treatment indicated as monotherapy in the treatment of adult patients with non-resectable or metastatic melanoma carrying a BRAF V600 mutation.
- Trial name
- NCT03108209
- Testing
- Photoderm Max lait SPF50+, Photoderm Max Stick SPF50+
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Michele Sayag
Phototoxicity
Evaluation of Potential Phototoxicity Skin Reaction After Use of MC2-01 Cream
This trial is a 4-day, randomized study to determine the phototoxic potential of MC2-01 Cream when topical application to healthy skin is followed by light exposure.
- Trial name
- NCT03892564
- Testing
- MC2-01 Cream, irradiation, MC2-01 Cream, no irradiation, MC2-01 vehicle, irradiation
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- MC2 Therapeutics
Diaper Rash
BM Characterization Pilot
This is a prospective, pilot study to explore the relationship between an infant's nutrition, skin and stool composition at different ages.
- Trial name
- NCT03138057
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Kimberly-Clark Corporation
Healthy
Clinical Evaluation of the Photoallergy Potential of Atralin Gel
To assess the potential of tretinoin gel 0.05% and its vehicle to produce photoallergic reactions, measured as skin reactions following induction and challenge.
- Trial name
- NCT00603772
- Testing
- Atralin (tretinoin) gel, 0.05%
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Coria Laboratories, Ltd.
Diaper Rash
Prospective Two-Year Study to Assess Miconazole Nitrate Resistance in Neonates and Infants
The purpose of this study is to determine whether repeated use of 0.25% miconazole nitrate ointment in newborns and infants with a yeast infection in the diaper area causes the yeast to become resistant to the drug.
- Trial name
- NCT00702507
- Testing
- 0.25 % Miconazole Nitrate Ointment
- Where
- 8 sites in United States, Dominican Republic and 2 more
- Volunteers
- 200 people
- Sponsor
- Stiefel, a GSK Company
Diaper Rash
Evaluation of the Safety and Performance of LiNiDERM® in the Prevention of Infant Diaper Rash
Result of immaturity of the skin and factors promoting maceration and mechanical interactions, Irritant diaper dermatitis (IDD) can manifest as early as the third week of life.
- Trial name
- NCT03640897
- Testing
- Liniderm, Wipes, Water
- Where
- Poland
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Laboratoires Gilbert
Dermatitis, Phototoxic
Study to Learn More About the Potential of Antifungal Cream V61-044 Containing Trolamine to Cause Irritant Reaction of the Skin to Ultra Violet Light in Healthy Human Subjects
In this study researchers want to gather information about the potential of Antifungal Cream V61-044 containing Trolamine to produce a phototoxic reaction on the skin.
- Trial name
- NCT04531527
- Testing
- Butenafine HCl 1% (BAY1896425)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
High-grade Dysplasia in Barrett Esophagus, Non Small Cell Lung Cancer
Efficacy and Safety of a Sunscreen Against Porfimer Sodium-induced Phototoxicity to Visible Light
Photodynamic therapy (PDT) uses a combination of a drug, porfimer sodium, and a light from a non heated laser. The activation of the drug is done by illuminating abnormal areas using a fiber optic device.
- Conditions
- High-grade Dysplasia in Barrett Esophagus, Non Small Cell Lung Cancer, Esophageal Cancer
- Trial name
- NCT01256203
- Testing
- Solar Protection Formula SPF® 60, Photobiological testing
- Sponsor
- Pinnacle Biologics Inc.
Contact Dermatitis of Hand
Crossover Study to Evaluate the Efficacy of LED in Treating the Signs of Contact/Irritant Dermatitis of the Hand
This study is intended to be a cross over study. Subjects will treat one hand while the contralateral hand acts as a control. At the end of 6 weeks the subject will be instructed to cease treatment of the test hand and commence…
- Trial name
- NCT05497921
- Testing
- handLITE LED device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Steven Baker
Acne Vulgaris
A Study to Evaluate the Potential of Tazarotene Foam to Cause a Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers
The purpose of this study is to evaluate the potential of Tazarotene Foam to induce a phototoxic reaction when exposed to UV and VIS light on skin of healthy volunteers.
- Trial name
- NCT01115322
- Testing
- Tazarotene Foam without irradiation, Tazarotene Foam with UVA and UVB irradiation, Tazarotene Foam with UVA, UVB, and visible light
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Hepatitis C Virus
TMC435-TiDP16-C125 - Study in Healthy Volunteers to Evaluate the Potential of TMC435 to Increase the Sensitivity of the Skin Towards Exposure to Sun Light
The purpose of the study is to evaluate the potential effect of TMC435 on the sensitivity of the skin towards exposure to sunlight.
- Trial name
- NCT01124799
- Testing
- TMC435, Ciprofloxacin
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Healthy
Clinical Evaluation of the Phototoxic Potential of Xenaderm Ointment
The product is being tested to see if exposure to light causes toxic reactions on the skin.
- Trial name
- NCT00644917
- Testing
- Xenaderm
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Healthpoint
Contact Dermatitis
Effect of Tetrix on Alleviation of Burning,Itching Associated With Lesions of Contact Dermatitis
To determine if Tetrix Cream, when applied to the skin lesions on patients with contact dermatitis, improves the symptoms of burning and itching.
- Trial name
- NCT00646867
- Testing
- Tetrix
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Coria Laboratories, Ltd.
Irritant Contact Dermatitis
EpiCeram for Skin Protection in Healthcare Workers
This is an open-label study using a device currently prescribed by doctors. This means everyone involved in the study will know the name of the product, only one product will be used, and the U.S.
- Trial name
- NCT04793711
- Testing
- EpiCeram
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Primus Pharmaceuticals
Peristomal Skin Complication
Preliminary Evaluation of CASTLE Barrier Prototype UK
The purpose of this study is to provide preliminary assessment of the safety and performance of a novel barrier formulation (CASTLE) in a small population of subjects with irritated peristomal skin.
- Trial name
- NCT01530087
- Testing
- CASTLE barrier
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- Hollister Incorporated
Diaper Rash
Determination of Safety and Consumers' Satisfaction of Moussik Versus Desitin Creamy Ointment in Diaper Rash Prophylaxis
The purpose of this clinical observation is to evaluate the safety and consumers' satisfaction of Moussik vs Desitin Creamy ointment as a diaper rash protection product.
- Trial name
- NCT01167465
- Testing
- Moussik Diaper Rash Mousse, Desitin Creamy Ointment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Trima, Israel Pharmaceutical Products
Diaper Dermatitis
BM Collection From NICU Infants for Composition
The primary objective of this study is to collect feces from premature infants over a five weeks period to characterize its composition.
- Trial name
- NCT02570698
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Kimberly-Clark Corporation
Diaper Rash
A Clinical Study to Assess the Efficacy and Safety of a Healing Ointment on Diaper Rash
The goal of this clinical trial is to assess the efficacy and safety of a Healing Ointment in infants 2-24 months with mild to moderate diaper rash.
- Trial name
- NCT06015217
- Testing
- "Cetaphil Healing Ointment"
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Galderma R&D