Clinical trials: Irritation/Irritant
Head Lice
Dermal Safety Study to Evaluate Potential Irritation of Abametapir Lotion
The purpose of the study is to determine the irritation potential of repeat applications of abametapir lotion on normal skin.
- Trial name
- NCT02061813
- Testing
- Abametapir Lotion 0.74% w/w, Sodium Lauryl Sulfate, Saline 0.9%
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Irritation/Irritant, Sensitisation
Human Skin Safety Testing of Mitopure Topical Products Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
The objective of this study is to investigate the irritation and sensitization potential of multiple topically applied test articles (containing different concentrations of Mitopure), in a shared panel of healthy volunteers by…
- Trial name
- GLOW-Safety-2 (NCT06884215)
- Testing
- Mitopure Topical Formula 3, Mitopure Topical Formula 4
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Pressure Ulcer, Incontinence-associated Dermatitis
Histopathological Comparison Between Superficial Pressure Ulcers and Incontinence-associated Dermatitis
This study aims to identify differences and similarities between superficial pressure ulcers (category II and III) and incontinence-associated dermatitis (category IIA) at tissue level.
- Conditions
- Pressure Ulcer, Incontinence-associated Dermatitis, Irritant Contact Dermatitis, Diaper Rash
- Trial name
- NCT03685929
- Testing
- Punch skin biopsy
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Ghent
Skin Irritation
A 21-Day Topical Safety Study of Diltiazem Hydrochloride Using a Cumulative Irritant Patch Test Design
The purpose of the study is to determine whether Diltiazem Hydrochloride 2% Cream will cause irritation to skin on the back of healthy volunteers after repeated application over 21-days.
- Trial name
- NCT01821274
- Testing
- Diltiazem Hydrochloride 2% Cream, Vehicle Cream, 0.1% solution o sodium lauryl sulfate (SLS)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ventrus Biosciences, Inc
Healthy Volunteers
A Study to Evaluate the Skin Irritation Potential of PBI-100 Topical Cream in Healthy Participants
This is an open-label, single-arm, randomized, evaluator-blinded repeat insult patch testing (RIPT) study wherein test product is applied under an occlusive dressing to the upper back or arm continuously and repeatedly to the…
- Trial name
- NCT04882631
- Testing
- PBI-100 Topical Cream, Positive Control - Sodium laurel sulfate (SLS), PBI-100 Topical Cream, Vehicle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pyramid Biosciences