Clinical trials: Irritation; Vagina
Pregnancy Malaria, Bacterial Vaginoses
The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract
Malaria in pregnancy has devastating consequences for mother and foetus. WHO recommends intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) for asymptomatic women, but high-level parasite…
- Conditions
- Pregnancy Malaria, Bacterial Vaginoses, Trichomonas Vaginitis
- Trial name
- NCT04189744
- Testing
- IPTp-sulphadoxine-pyrimethamine plus metronidazole, IPTp-dihydroartemisinin-piperaquine plus metronidazole, IPTp-sulphadoxine-pyrimethamine
- Where
- Zambia
- Volunteers
- 5,436 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Chlamydia Trachomatis Infection, Vaginal Infection
Azithromycin Compared With Doxycycline for Treating Anorectal Chlamydia Trachomatis Infection Concomitant to a Vaginal Infection
Chlamydia trachomatis is the most commonly reported bacterial sexually transmitted infection (STI), especially among young women. Up to 75% of C. trachomatis infected women are asymptomatic. If untreated, C.
- Conditions
- Chlamydia Trachomatis Infection, Vaginal Infection, Anal Infection
- Trial name
- CHLAZIDOXY (NCT03532464)
- Testing
- azithromycin, doxycycline
- Where
- 7 sites in France
- Volunteers
- 460 people
- Sponsor
- University Hospital, Bordeaux
Vulvovaginal Candidiasis
DeVEnIR: Defining Vulvovaginal Candidiasis - Elements of Infection and Remedy
Female-specific health conditions are underrepresented in research. The taboo felt by women to talk about intimate wellbeing is fed by this gender gap in scientific knowledge.
- Trial name
- DeVEnIR (NCT06397248)
- Testing
- No intervention
- Where
- 3 sites in Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Vaginal Candidiasis, Vulvovaginal Candidiasis
Evaluation of VagiVitalAC for Treatment of Candida Vulvovaginitis
Candidiasis is an infection caused by a yeast (a type of fungus) called Candida. Candidiasis in the vagina is commonly called a "vaginal yeast infection." Another names for this infection is "vaginal candidiasis".
- Conditions
- Vaginal Candidiasis, Vulvovaginal Candidiasis, Candidal Vulvovaginitis
- Trial name
- NCT05012852
- Testing
- VagiVitalAC
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- PepTonic Medical AB
Bacterial Vaginosis (BV)
Efficacy and Safety of Vaginal Lactobacillus Dual Probiotic Capsules in Bacterial Vaginosis
Primary Objective: To confirm that the clinical cure rate of Vaginal Lactobacillus Dual Probiotic Capsules for bacterial vaginosis (BV) is superior to placebo at the 21-30 day post-treatment visit (Day 21 to Day 30).
- Trial name
- BV (NCT07418957)
- Testing
- Vaginal Lactobacillus Dual Probiotic Capsules
- Where
- China
- Volunteers
- 402 people
- Sponsor
- Guangdong Longchuangji Pharmaceutical Co., Ltd.
Bacterial Vaginosis, Vaginal Dysbiosis
AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth
Preterm birth is a major cause of mortality and long-term disability. Bacterial vaginosis (BV) is a frequent form of dysbiosis that is often asymptomatic and increases the risk of preterm birth.
- Conditions
- Bacterial Vaginosis, Vaginal Dysbiosis, Premature Delivery
- Trial name
- AUTOP 2 (NCT06349122)
- Testing
- Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone
- Volunteers
- 1,794 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Bacterial Vaginosis
Safety and Efficacy Study of Lactobacillus Administered Vaginally in Women With Bacterial Vaginosis
This is a phase IIa clinical trial in women with bacterial vaginosis. This study will determine whether treatment with vaginal lactobacillus in combination with antibiotic therapy (metronidazole) is effective in colonizing the…
- Trial name
- NCT00635622
- Testing
- LACTIN-V
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Osel, Inc.
Vaginal Infections
Comparison of Two Topical Formulations Containing Clindamycin and Clotrimazole in Patients With Vaginal Infections
Randomized, Parallel Group, Active Controlled Trial to compare effectiveness and tolerability of 2 different vaginal formulations containing 200mg clotrimazole and clindamycin phosphate equivalent to 100mg clindamycin for 3 days…
- Trial name
- NCT01697826
- Testing
- ClinSupV3 -soft gelatin capsule, ClinSupV3ER- Extended release tablet
- Where
- India
- Volunteers
- 73 people
- Sponsor
- Dr Bharti Daswani
Vaginosis, Bacterial
Safety, Tolerability and Efficacy of Vaginal Suppository WO3191 in the Post-treatment of Bacterial Vaginosis
Bacterial Vaginosis (BV) is a common infectious disorder and is characterized by a disturbance in the vaginal microbiological milieu.
- Trial name
- NCT02687789
- Testing
- Medical Device: WO3191, Medical Device: Vagisan® Lactic Acid
- Where
- 13 sites in Germany
- Volunteers
- 43 people
- Sponsor
- Dr. August Wolff GmbH & Co. KG Arzneimittel
Bacterial Vaginosis
Safety and Efficacy Study to Treat Bacterial Vaginosis
The purpose of this study is to determine if product 55394 is safe and efficacious for the treatment of bacterial vaginosis.
- Trial name
- NCT01621399
- Testing
- Product 55394
- Where
- 37 sites in United States
- Volunteers
- 651 people
- Sponsor
- Medicis Global Service Corporation
Vaginosis, Bacterial, Infertility
Efficacy Study of Preconception Treatment of an Asymptomatic Bacterial Infection in an Infertility Population
Bacterial vaginosis (BV) is a common vaginal infection characterized by a pathologic shift in the normal vaginal flora. BV has been associated with a number of poor reproductive outcomes, including infertility, preterm labor and…
- Conditions
- Vaginosis, Bacterial, Infertility, Miscarriage
- Trial name
- NCT01322971
- Testing
- Metronidazole
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pelvic Floor Dysfunctions
Effectiveness of Modern Physical Agents in the Treatment of Pelvic Floor Dysfunctions
This clinical trial aims to determine whether adding modern physical agents (high-intensity laser therapy, magnetotherapy, radial shock wave therapy, kinesiotaping) in conjunction with classical rehabilitation interventions…
- Trial name
- EMPHAT-PFD (NCT06800222)
- Testing
- modern agents rehab, classical rehab
- Where
- Lithuania
- Volunteers
- 250 people
- Sponsor
- Lithuanian University of Health Sciences
Vaginitis Bacterial, Inflammation, Ear
Effect of Lactobacillus Johnsonii or White Pomegranate Extract on the Vaginal Health
The goal of this clinical trial is to explore the effect of Lactobacillus johnsonii and white pomegranate extract on female bacterial status, it aims to answer are: Evaluate Lactobacillus johnsonii TCI250 probiotics or white…
- Trial name
- NCT06069531
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chung Shan Medical University
Bacterial Vaginosis, Fungal Vaginal Infections
Clinical Protocol CERN Feasibility Study
The goal of this clinical trial is to learn if the intravaginal Cern device works to treat bacterial vaginosis and fungal vaginitis in premenopausal women. It will also learn about the safety of the device.
- Trial name
- NCT06933420
- Testing
- Cern Device
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Cern Corporation
Bacterial Vaginosis, Vaginal Flora Imbalance
Clinical Trial to Survey Results of Flourish Vaginal Care System for Recurrent Bacterial Vaginosis
Background Bacterial Vaginosis is the most common vaginal infection in women in their reproductive years and a difficult one to treat.
- Trial name
- NCT03734523
- Testing
- Flourish Vaginal Care System
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Vaginal Biome Science
HPV Genital Infection (Primary Condition Studied), Bacterial Vaginosis
Kinetics and Ecology of Human Papillomavirus Genital Infections in Young Women
Most genital infections by human papillomaviruses (HPV) are asymptomatic or benign and clear within a few months or years. There infections are much less studies than chronic infections, even though they represent the main…
- Conditions
- HPV Genital Infection (Primary Condition Studied), Bacterial Vaginosis, Chlamydiae Infection
- Trial name
- PAPCLEAR (NCT02946346)
- Testing
- vaginal sampling
- Where
- France
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
BACTERIAL VAGINOSIS
Efficacy and Safety Study of Rifaximin Vaginal Tablets in Bacterial Vaginosis
THE STUDY HAS BEEN DESIGNED TO COMPARE THE EFFICACY OF TWO DOSES (25 MG AND 100 MG) OF RIFAXIMIN VAGINAL TABLETS VERSUS PLACEBO IN SUBJECTS WITH BACTERIAL VAGINOSIS
- Trial name
- VARIANT (NCT02376972)
- Testing
- RIFAXIMIN VAGINAL TABLET 25 MG, RIFAXIMIN VAGINAL TABLET 100 MG, METROGEL VAGINAL
- Where
- United States
- Volunteers
- 392 people
- Sponsor
- Alfasigma S.p.A.
Recurrent Bacterial Vaginosis
Evaluation of the Ability of Lactobacillus Crispatus CRP21 to Reduce the Incidence of Recurrent Bacterial Vaginosis
Recurrent bacterial vaginosis is a common condition in women of reproductive age and is characterized by a disruption of the normal vaginal microbiota, with a reduction in Lactobacillus species and an overgrowth of anaerobic…
- Trial name
- NCT07474831
- Testing
- Lactobacillus crispatus CRP21
- Where
- 11 sites in Italy
- Volunteers
- 132 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Bacterial Vaginosis
Treatment of Bacterial Vaginosis Combined With Human Lactobacilli
The primary objectives of this study were to characterize lactobacilli of human vaginal origin and to investigate if more extended antibiotic treatment against Bacterial Vaginosis, together with adjuvant lactobacilli treatment…
- Trial name
- NCT01245322
- Testing
- lactobacilli
- Where
- Norway
- Volunteers
- 75 people
- Sponsor
- Skaraborg Hospital
Vaginosis, Bacterial, Vaginal Infection
Dose Ranging Study of Metronidazole Vaginal Gel in the Treatment of Bacterial Vaginosis
The objective of this study is to evaluate the efficacy and safety of GW05 administered in 3 regimens versus metronidazole 0.75% for the treatment of bacterial vaginosis.
- Trial name
- NCT01055106
- Testing
- GW05, Metronidazole
- Where
- 20 sites in United States
- Volunteers
- 255 people
- Sponsor
- Graceway Pharmaceuticals, LLC