Clinical trials: Irritation
Irritable Bowel Syndrome
Effect of a Cannabinoid Agonist on Colonic Sensory Functions in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) affects about 15% of the U.S. population. There are still no effective and safe medications approved for the treatment of abdominal pain associated with bowel symptoms in IBS.
- Trial name
- NCT01786109
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Michael Camilleri
Irritable Bowel Syndrome
Group Hypnosis for Irritable Bowel Syndrome
This randomised controlled trial (RCT) aimed at assessing the efficacy of hypnotherapy in group sessions (GHT) with a 12-months follow-up.
- Trial name
- IBS (NCT01178593)
- Testing
- Gut-focused hypnotherapy in group sessions
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Skin Irritation
Effect of Vitamin D After Application With Valchlor
The purpose of this research study is to evaluate the effects of an oral Vitamin D on the body's immune system. An interest has been growing because studies have shown that Vitamin D may reduce inflammation and harmful effects in…
- Trial name
- NCT02968446
- Testing
- 4 Vitamin D, Valchlor
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University Hospitals Cleveland Medical Center
Bowel Symptoms, Depression Disorders
The Effect of Inulin in Irritable Bowel Syndrome
Purpose: This study was conducted to evaluate the effect of inulin on bowel symptoms, depression and quality of life in individuals with constipation-dominant irritable bowel syndrome.
- Conditions
- Bowel Symptoms, Depression Disorders, Inulin, Constipation
- Trial name
- NCT06610188
- Testing
- Prebiotic group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Irritable Bowel Syndrome
Efficacy of Rifaximin to Treat Diarrhea-predominant Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a common disease and the pathogenesis of this disease includes central and peripheral mechanisms.
- Trial name
- NCT02565654
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Irritable Bowel Syndrome
Effect of Acupuncture on Symptoms of Diarrhea and Pain in IBS
Acupuncture has been used for centuries in China in the treatment of diarrhea. Our hypothesis is that acupuncture is effective in the treatment of abdominal pain and diarrhea in patients with diarrhea-predominant IBS
- Trial name
- NCT00219505
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Penn State University
Tooth Discolouration
16% Carbamide Peroxide Home Bleaching: Soft vs. Rigid Tray in a Randomized Blinded Equivalence Trial
The aim of this clinical study is to evaluate patient satisfaction, bleaching efficacy, and the risk and severity of tooth sensitivity and gingival irritation during home bleaching with 16% carbamide peroxide using conventional…
- Trial name
- Rigid tray (NCT06881654)
- Testing
- Bleaching teeth
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Rey Juan Carlos
Diarrhea-predominant Irritable Bowel Syndrome
Allogeneic Microbiota-reconstitution (AMR) in Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)
The investigators will perform a multicenter, 2:1 randomized, double-blinded, placebo-controlled trial of AMR in patients with diarrhea predominant-IBS (IBS-D) diagnosed according to Rome III criteria and the IBS-QOL…
- Trial name
- AMIRA (NCT04095988)
- Testing
- Allogeneic microbiota reconstitution
- Where
- 2 sites in Germany
- Volunteers
- 42 people
- Sponsor
- University of Ulm
Hygiene
Dermacyd Infantile (Lactic Acid)- Compatibility.
Primary Objective: To demonstrate the absence of irritation potential (primary dermic irritability and cumulated dermic irritability) and allergic potential (sensibilization) of the product Dermacyd Infantile.
- Trial name
- NCT00881374
- Testing
- LACTIC ACID(ND)
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sanofi
Irritable Bowel Syndrome, Lactose Intolerance
The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION)
Irritable bowel syndrome (IBS) is a functional gastrointestinal disease. There is no well-defined pharmacological treatment. This clinical trial is a prospective, double-blind, two-armed randomized controlled, single-center…
- Conditions
- Irritable Bowel Syndrome, Lactose Intolerance, Lactose Malabsorption
- Trial name
- LION (NCT05100719)
- Testing
- alverine-citrate + simethicone and lactase
- Where
- Hungary
- Volunteers
- 200 people
- Sponsor
- University of Pecs
Irritable Bowel Syndrome With Diarrhoea
Ondansetron for the Treatment of IBS With Diarrhoea (IBS-D)
Irritable bowel syndrome is a common condition affecting 1 in 10 of the population. About a third of these suffer from diarrhoea, which severely impairs their quality of life.
- Trial name
- NCT00745004
- Testing
- Ondansetron
- Where
- 2 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Nottingham
Gulf War Illness
Probiotic (Visbiome) for Gulf War Illness
The overall objective is to determine whether Visbiome will improve 1. intestinal symptoms of Irritable Bowel Syndrome (IBS) and 2.
- Trial name
- NCT03078530
- Testing
- Visbiome, VSL#3
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ashok Tuteja
IBS-D (Diarrhea-predominant)
Effect of Ramosetron in Patients With Diarrhea Predominant Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) tends to be a lifelong disorder and it is often frustrating to both patients and physicians. This study aim of improving symptom control, reducing healthcare burden and upgrading the quality of life…
- Trial name
- NCT07574320
- Testing
- Ramosetron 2.5 microgram
- Volunteers
- 76 people
- Sponsor
- Md. Aminul Islam
Irritable Bowel Syndrome Characterized by Constipation
Trial of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation
The objective of this trial is to determine the efficacy and safety of linaclotide administered to patients with irritable bowel syndrome with constipation (IBS-C).
- Trial name
- NCT00948818
- Testing
- Linaclotide 290 micrograms
- Where
- 118 sites in United States, Canada
- Volunteers
- 803 people
- Sponsor
- Forest Laboratories
Irritable Bowel Syndrome With Diarrhea, Effects of Probiotics
Multi Strain Probiotic Preparation in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders characterized by recurrent abdominal pain associated with defecation or a change in bowel habits without any structural abnormalities.
- Trial name
- NCT04662957
- Testing
- Maltodextrin
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Children's Memorial Health Institute, Poland
Functional Dyspepsia, Irritable Bowel Syndrome With Diarrhea
Efficacy and Mechanistic Evaluation of Hewei Anchang Formula for Overlapping Gastrointestinal Symptoms in Patients With Coexisting Functional Dyspepsia and Diarrhea-Predominant Irritable Bowel Syndrome
1. To conduct a multicenter, randomized controlled trial across four hospitals to evaluate the efficacy of Hewei Anchang Formula in patients with overlapping gastrointestinal symptoms of functional dyspepsia (FD) and…
- Trial name
- NCT07715760
- Testing
- Hewei Anchang Formula Granules
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Irritable Bowel Syndrome
Effect of Antibiotic Pretreatment on the Efficacy of WMT in the Treatment of Irritable Bowel Syndrome
This is a randomized controlled trial to explore the efficacy of antibiotic pretreatment on the efficacy of WMT in the treatment of Irritable bowel syndrome in adults: a multi-center, randomized, placebo-controlled clinical study
- Trial name
- NCT06437041
- Testing
- Ornidazole
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Faming Zhang
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Measurement and Analysis of Gas Composition in Digestive Tract
The purpose of this study is to detect the concentration of various gases，including hydrogen, methane, hydrogen sulfide, nitric oxide in different parts of the digestive tract by a safe and direct method, and to establish a human…
- Conditions
- Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Functional Dyspepsia, Colorectal Neoplasms
- Trial name
- NCT05810805
- Testing
- gas component of digestive tract
- Where
- China
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Xiuli Zuo
Irritable Bowel Syndrome, Dyspepsia
Functional Digestive Disorders Observatory
Functional digestive pathologies are defined by symptoms such as functional dyspepsia, gastroesophageal reflux, irritable bowel syndrome, gastroesophageal reflux, functional constipation, functional diarrhea, functional bloating…
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Constipation, Faecal Incontinence
- Trial name
- OTFI (NCT04918329)
- Testing
- Observational study
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Rouen
Ocular Redness, Eye Irritation
An Investigation of FID 123320 for the Reduction of Ocular Redness in Pediatric and Adult Populations
The purpose of this study is to assess the safety and efficacy of FID 123320 Ophthalmic Solution compared to Vehicle for relieving redness of the eye due to minor eye irritations in pediatric and adult populations.
- Trial name
- NCT06538662
- Testing
- FID 123320 Ophthalmic Solution, Vehicle
- Where
- 10 sites in United States
- Volunteers
- 283 people
- Sponsor
- Alcon Research
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