Clinical trials: Irritation
Irritable Bowel Syndrome
Dietary Treatment for IBS Within Primary Health Care
Irritable bowel syndrome (IBS) is a multifaceted disorder where diet plays a pivotal role in symptom generation and management. The traditional dietary advice given to patients in clinical settings are based on the NICE…
- Trial name
- KIPIBS (NCT05415488)
- Testing
- Online dietary group treatment
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Sahlgrenska University Hospital
Irritable Bowel Syndrome, Children
Immunological Change and the Single Nucleotide Polymorphism (SNP) in Children With Irritable Bowel Syndrome (IBS)
Currently, the pathophysiology of Irritable bowel syndrome( IBS) remains unclear . The purpose of this study is want to investigate the immunological changes in the children with IBS.
- Trial name
- NCT01131442
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Irritable Bowel Syndrome
Developing Novel Microbiota-Targeted Therapies for Irritable Bowel Syndrome
This longitudinal study is being done to understand mechanisms underlying development of irritable bowel syndrome (IBS) and the role of the gut bacteria in development of symptoms.
- Trial name
- NCT02249169
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy
Dermatological Evaluation of Topic Compatibility-Dermacyd Delicata Pocket BR
The purpose of this study is to demonstrate the absence of irritation potential (primary dermal irritability and cumulated dermal irritability) and allergy (sensibilization) of the product Dermacyd Pocket BR.
- Trial name
- NCT00668460
- Testing
- Lactic acid (Dermacid)
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sanofi
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea
Personalized Dietary Intervention Based on Microbiome Analysis vs FODMAP Diet for Irritable Bowel Syndrome
irritable bowel syndrome (IBS) is a well-known risk factor for diseases of the anal region (hemorrhoids, anal fissures, etc.) and large intestine (colon cancer, diverticular disease).
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Constipation, Irritable Bowel Syndrome Mixed
- Trial name
- NCT05646186
- Testing
- Personalized dietary intervention based on microbiome analysis, Low-FODMAP diet
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Medipol University Hospital
Irritable Bowel Syndrome
Psyllium in Pediatric IBS
The goal of this clinical trial is to learn if a fiber (psyllium) can change the way bacteria use fructans (a type of sugar) and whether psyllium can help decrease childhood irritable bowel syndrome (IBS) symptoms when eating…
- Trial name
- Psyllium (NCT06639984)
- Testing
- Psyllium (0.7 g/year of age per day), Psyllium (0.5 g/year of age per day), fructans
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Dr Bruno Chumpitazi, M.D.
Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders
i-CBT Functional Gastrointestinal Disorders in Youth: the Impact of Negative Illness Understanding and Parental Illness Worries
The aim of the current study, embedded in The Danish FGID Treatment Study, is to test Danish versions of Swedish i-CBT programs for children and adolescents with FGID in a Danish clinical context and to further evaluate the…
- Conditions
- Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
- Trial name
- NCT05486585
- Testing
- Internet delivered cognitive behavioural therapy for functional gastrointestinal disorders
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis), Central Retinal Vein Occlusion With Macular Edema
Cool vs Room-temperature Artificial Tears
Background and Objective: To evaluate the efficacy of cooled versus room temperature artificial tears in reducing post intravitreal injection (IVI) ocular discomfort.
- Conditions
- Diabetic Retinopathy With Macular Edema of Both Eyes (Diagnosis), Central Retinal Vein Occlusion With Macular Edema, Exudative Age-Related Macular Degeneration, Unspecified Eye, Cystoid Macular Edema
- Trial name
- NCT05832996
- Testing
- Refresh Plus Preservative-free Lubricant Eye Drops
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Irritable Bowel Syndrome
The Effect of Coltect (Selenium, Curcumin and Green Tea) on Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) causes many symptoms, including abdominal pain, irregular bowel movements and bloating. It may be caused by loe degree inflammation of the intestine.
- Trial name
- NCT01167673
- Testing
- coltect
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- NAFTALI TIMNA
Irritable Bowel Syndrome
Effect of BIO-K+ on Symptoms of Irritable Bowel Syndrome
The purpose of this study is to evaluate the safety and effectiveness of Bio-K+ on symptoms of IBS.
- Trial name
- NCT01545037
- Testing
- L. acidophilus CL1285® + L. casei LBC80R® + L. rhamnosus CLR2®
- Where
- 3 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Bio-K Plus International Inc.
Irritable Bowel Syndrome
Effect of Pre-dosing With Methylcellulose or Psyllium on Colonic Fermentation of Inulin
The aim for this pilot study is to test the hypothesis that pre-dosing with gel-forming dietary fibres (methylcellulose or psyllium) will alter the colonic fermentation of a model fermentable dietary fibre (Inulin) when delivered…
- Trial name
- COCOA3 (NCT06494137)
- Testing
- inulin
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Irritable Bowel Syndrome
The Effect of Hot Cataplasm With Caraway Oil in the Treatment of Irritable Bowel Syndrome
The purpose of this study is to determine whether a daily use of a Kneipp hot cataplasm with caraway oil is effective in the treatment of abdominal pain and complaints caused by Irritable bowel syndrome.
- Trial name
- CarO (NCT01418053)
- Testing
- caraway oil, Olive oil
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Universität Duisburg-Essen
IBS - Irritable Bowel Syndrome
Effects of a Novel Machine Learning Mobile App on Diet Adherence in Individuals Following the Low Fodmap Diet
A high fermented, oligio-, di-, monosaccharide, and polyols (FODMAP) diet has been shown to exacerbate the symptoms of irritable bowel syndrome (IBS).
- Trial name
- NCT04256551
- Testing
- Heali mobile application + Registered Dietitian, Heali mobile application, Standard Dietary Education
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Arizona State University
Irritable Bowel Syndrome Characterized by Constipation
A Study of the Effect of Linaclotide on Abdominal Girth in Participants With Irritable Bowel Syndrome With Constipation (IBS-C)
The objective of this trial is to determine the effect of linaclotide on abdominal girth in IBS-C participants with the baseline symptoms of abdominal bloating and an increased abdominal girth.
- Trial name
- NCT02837783
- Testing
- Linaclotide
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Ironwood Pharmaceuticals, Inc.
Irritable Bowel Syndrome
Probiotics and Irritable Bowel Syndrome
This clinical trial was conducted on 90 IBS patients, who fulfill ROME IV criteria and the IBS diagnostic questionnaire (Arabic version licensed by Rome Foundation) in Egyptair hospital outpatient clinic, Cairo, Egypt between May…
- Trial name
- NCT04572932
- Testing
- lactobacillus delbruekii
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Pterygium
Manifestations of Ocular Irritation Following Pterygium Excision With Sutures Fixed Conjunctival Autograft
In this work, the manifestations of ocular irritation associated with vicryl 8/0 sutures fixed conjunctival auto-graft in pterygium patients were evaluated.
- Trial name
- NCT05164900
- Testing
- pterygium excision with sutures fixed conjunctival auto-graft
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Tanta University
Irritable Bowel Syndrome With Constipation
Electro-acupuncture for Irritable Bowel Syndrome With Constipation
The aim of the clinical trial is to evaluate the efficacy and safety of electro-acupuncture for irritable bowel syndrome with constipation (IBS-C) patients.
- Trial name
- NCT06219707
- Testing
- Acupuncture needles
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Irritable Bowel Syndrome
A Four Arm Study to Evaluate the Safety and Efficacy of 3 Different Doses of RVX-100 Versus Placebo in Subjects With Irritable Bowel Syndrome Accompanied by Diarrhea (IBS-D)
The purpose of this study is to determine if RVX-100 is safe and effective in treating acute abdominal pain in patients with irritable bowel syndrome accompanied by diarrhea.
- Trial name
- NCT01076699
- Testing
- 0.075 mg RVX-100, 0.125 mg RVX-100, 0.250 mg RVX-100
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Revogenex, Inc.
Urticaria
Monitoring Chronic Urticaria Basophil Irritability by Cytometry
A biological tool for quantitative assessment of Chronic Urticaria (CU) is still in need for monitoring biotherapies. CU is considered as a sudden degranulation of Mast cells / basophils without any identified cause.
- Trial name
- CUBIC (NCT02671006)
- Testing
- Basophil patterns
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Irritable Bowel Syndrome
Calisthenics Versus Cycling Exercises on Interleukin-6 and Quality of Life in Benha University Students With Irritable Bowel Syndrome
this study will be conducted to compare between the effect of calisthenics versus cycling exercises on interleukin-6 and quality of life in Benha University students with irritable bowel syndrome.
- Trial name
- IBS (NCT07760298)
- Testing
- Calisthenics exercises, Cycling Exercises, diet advices
- Volunteers
- 60 people
- Sponsor
- Cairo University
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