Clinical trials: Irritation
Pouchitis, Irritable Pouch Syndrome
Efficacy of Liraglutide Therapy in Patients With IPAA
Patients with an ileal pouch-anal anastomosis(IPAA; pouch) due to refractory inflammatory bowel disease and increased bowel frequency in the absence of significant pouch inflammation will be randomized to liraglutide or placebo…
- Trial name
- NCT04763564
- Testing
- Liraglutide Pen Injector
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of North Carolina, Chapel Hill
Irritable Bowel Syndrome
Defining Objective Markers of Compliance for Dietary Therapies in IBS
This research will investigate if a specific marker in your stool or urine can be used to track changes in your carbohydrate intake including fructo-oligosaccharide and mannitol intake
- Trial name
- NCT07494968
- Testing
- Diet A - elimination diet, Diet B - healthy eating diet
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Michigan
Irritable Bowel Syndrome
A Study of 3 Doses of Dextofisopam in Females With Irritable Bowel Syndrome
The primary objectives of this study are to evaluate the clinical safety and tolerability and to assess the efficacy of 100 mg, 200 mg, and 300 mg BID dextofisopam compared with placebo in female outpatients with…
- Trial name
- NCT00486876
- Testing
- Dextofisopam
- Where
- 79 sites in United States
- Volunteers
- 324 people
- Sponsor
- Pharmos
IBS - Irritable Bowel Syndrome
Lifestyle Eating and Performance (LEAP) Program for the Treatment of Irritable Bowel Syndrome (IBS)
A three month follow-up study to evaluate the effectiveness of a tailored anti-inflammatory eating plan guided by a registered dietitian to treat irritable bowel syndrome.
- Trial name
- NCT05178017
- Testing
- Leukocyte Activation Assay (LAA-MRT) / Lifestyle Eating and Performance (LEAP) program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Oxford Biomedical Technologies, Inc.
Pain Syndrome, Propofol Infusion Syndrome
Warm Patch Decrease Propofol Injection Pain
Propofol causes injection pain is still a common clinical unsolved problem. Mixing a small amount of lidocaine with propofol or injecting lidocaine in advance can reduce the pain caused by propofol injection.
- Conditions
- Pain Syndrome, Propofol Infusion Syndrome, Injection Site Irritation
- Trial name
- NCT04555980
- Testing
- Warming patch, Cotton patch
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First People's Hospital of Chenzhou
Pain, Neuropathic Pain
Efficacy of Gabapentin in Treating Pain in Children With SNI (Gabapentin Trial)
Children born with severe brain-based developmental disabilities frequently experience persistent unexplained periods of pain and irritability, often compounded by a limited capacity to communicate their distress.
- Conditions
- Pain, Neuropathic Pain, Irritability
- Trial name
- NCT04619862
- Testing
- Gabapentin
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
Irritable Bowel Syndrome, Dyspepsia
Treatment of Functional Abdominal Distension
Background. Abdominal distention is produced by an abnormal somatic postural tone. We developed an original biofeedback technique based on electromyography-guided control of abdominothoracic muscular activity.
- Trial name
- NCT04043208
- Testing
- Biofeedback
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Irritable Bowel Syndrome
Effects of the Soluble Mediators of Mastocytes on the Intestinal Epithelial Barrier and of the Enteric Nervous System During the Syndrome of the Irritable Bowel
Patients with irritable bowel syndrome (IBS) have increased intestinal permeability. In addition, mucosal soluble mediators are involved in the pathophysiology of pain in IBS. The investigators aimed to investigate: 1.
- Trial name
- NCT00742118
- Testing
- Colic biopsies
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
IBS - Irritable Bowel Syndrome, Diarrhea
A Multi-Strain Probiotic Reduces the Frequency of Diarrhea in IBS-D Patients
The goal of this interventional clinical study is to study whether the consumption of QiMeiYan Probiotics in 25-35 young people with Mild irritable bowel syndrome (IBS Score 75 - 175) will reduce the frequency of Diarrhea.
- Trial name
- NCT05900752
- Testing
- QiMeiYan Probiotics
- Where
- 2 sites in China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Shenzhen Precision Health Food Technology Co. Ltd.,
Irritable Bowel Syndrome, Fibromyalgia
Clinical Trial Examining Effects of Monosodium Glutamate (MSG) on Irritable Bowel Syndrome (IBS) and Fibromyalgia (FM)
Objective: Randomized, double blind, placebo-controlled, crossover, clinical trial to examine the effects of the food additive glutamate (in the form of MSG) on IBS and fibromyalgia.
- Trial name
- NCT00829218
- Testing
- Glutamate additive-free diet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Oregon Health and Science University
Hygiene
Dermacyd PH_DETINLYN (Lactic Acid) Tangerine Mix - Compatibility
The purpose of this study is to demonstrate the absence of irritation potential (primary dermic irritability and cumulated dermic irritability) and allergy (sensibilization) of the product Dermacyd PHDETINLYN Tangerine Mix.None.
- Trial name
- NCT00786097
- Testing
- Dermacyd PH_DETINLYN (Lactic Acid)
- Where
- Brazil
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Sanofi
Irritable Bowel Syndrome
Assessment of the Symbiotic Fermented Milk in Patients With Irritable Bowel Syndrome
This study evaluates the effect of a symbiotic fermented milk on health-related quality of life and irritable bowel syndrome (IBS) symptoms in patients with constipation-predominant IBS.
- Trial name
- NCT02391220
- Testing
- LCA symbiotic fermented milk, heat-treated fermented milk
- Volunteers
- 76 people
- Sponsor
- Clinres Farmacija d.o.o.
Irritable Bowel Syndrome - Diarrhoea
Effect of Ebastine in Patients With Diarrhea Predominant Irritable Bowel Syndrome
The goal of this clinical trial is to assess and compare the effect of ebastine and placebo in improving symptoms in patients with diarrhea predominant IBS.
- Trial name
- NCT07114055
- Testing
- ebastine
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Md. Hazrat Ali
Premenstrual Syndrome, Uterus; Hemorrhage, Preclimacteric or Premenopausal
GAMALINE®+HIPERICIN® for PMS Treatment and Vasomotor Symptoms
2 phytomedicines already in the market: GAMALINE® for premenstrual syndrome and HIPERICIN® as antidepressant will be prescribed together for treating women with Premenstrual Syndrome (PMS) symptoms and vasomotor problems for…
- Trial name
- 657/10UFCSPA (NCT01365676)
- Testing
- GAMALINE® + HIPERICIN®, GAMALINE®
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Phytopharm Consulting Brazil
Fragile X Syndrome
Biomarker Testing and DNA Collection in Subjects Participating in Protocol 22001
The subjects that meet the inclusion and exclusion criteria and consent to participate in protocol 22001 will be offered participation in 22001A which will evaluate secreted protein before and after treatment with STX209 and…
- Trial name
- NCT00823368
- Testing
- STX209
- Where
- 11 sites in United States
- Sponsor
- Seaside Therapeutics, Inc.
Constipation, Chronic Idiopathic Constipation
The Effect of CSP01 on Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation
Constipation is a common gastrointestinal motility disorder that is often chronic, negatively affects patients' daily lives. Constipation occurs when bowel movements become difficult or less frequent.This study is being done to…
- Conditions
- Constipation, Chronic Idiopathic Constipation, Irritable Bowel Syndrome With Constipation
- Trial name
- NCT03054506
- Testing
- CSP01, Carboxymethylcellulose (CMC)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Massachusetts General Hospital
IBS - Irritable Bowel Syndrome
Yogic Breathing and IBS
Adults with irritable bowel syndrome (IBS) are being randomized to a yogic breathing or control condition. Participants randomized to the yogic breathing group will be asked to complete a 2-minute yogic breathing video 5 to 7…
- Trial name
- NCT04225104
- Testing
- Yogic breathing intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Texas State University
Diarrhea-Predominant Irritable Bowel Syndrome
Changyanning Tablet for the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)
The goal of this clinical trial is to test the efficacy and safety of the Chinese patent medicine Changyanning Tablet in the patients with Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D).
- Trial name
- NCT05687435
- Testing
- Changyanning tablet
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Mei Han
Functional Constipation, Irritable Bowel Syndrome
Colonoscopic Probiotics Infusion for Functional Gastrointestinal Disease
The purpose of this project is to study the the efficacy and safety of probiotics implantation through infusion during colonoscopy in the treatment of functional constipation and irritable bowel syndrome.
- Conditions
- Functional Constipation, Irritable Bowel Syndrome, Probiotics, Colonoscopy
- Trial name
- CPIFGD (NCT05366335)
- Testing
- Live Combined Bifidobacterium and Lactobacillus, Normal saline, Basic treatment
- Where
- China
- Volunteers
- 160 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Primary Headache Disorder
Primary Headaches and Irritable Bowel Syndrome.
To assess the relationship between primary headaches and irritable bowel syndrome
- Trial name
- NCT05057533
- Testing
- a questionnaire based on Rome IV Diagnostic criteria of IBS
- Where
- Egypt
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Assiut University
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