Clinical trials: Ischemia, Brain
Stroke Ischemic
Effect of Repetitive Transcranial Magnetic Stimulation on Neurological Recovery in Patients With Ischaemic Stroke
The goal of this clinical trial is to learn if transcranial magnetic stimulation(rTMS) can improve neurological rehabilitation in patients with acute ischemic stroke.
- Trial name
- NCT06415734
- Testing
- rTMS
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Acute Ischemic Stroke, Nursing
Feasibility and Effectiveness of Rehabilitation Nursing for Acute Stroke
In the clinical setting, it is difficult to obtain effective rehabilitation during the acute phase, the reasons may include insufficient awareness of early rehabilitation due mainly to a limitation in number and variety of…
- Trial name
- NCT04402736
- Testing
- The modified Barthel Index-based rehabilitation nursing program, Usual care
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke
Post-Stroke Secondary Prevention With Digital Monitoring
Stroke is the second leading cause of death and a major cause of disability worldwide. In 2019, Disability-Adjusted Life-Years (DALYs) related to stroke was estimated to have reached 143 million.
- Trial name
- PSDM (NCT06837311)
- Testing
- Ecological Momentary Assessment (EMA), Biological assessment, Psychological examination and Substance Use symptomatology
- Where
- France
- Volunteers
- 388 people
- Sponsor
- University Hospital, Bordeaux
Coronary Artery Disease, Atrial Fibrillation (AF)
Medical Large Language Model-Assisted Diagnosis and Treatment in Primary Care Chronic Disease Management
This study aims to explore the feasibility of using medical large language models to assist in chronic disease management. By setting up experimental and control group interventions and having experts blindly evaluate anonymized…
- Conditions
- Coronary Artery Disease, Atrial Fibrillation (AF), Heart Failure, Stroke
- Trial name
- NCT07740044
- Testing
- Medical large language model
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Jiangsu Taizhou People's Hospital
Ischemic Stroke, Cognitive Impairment
Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke
The purpose of this study is to determine whether a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), combined with traditional cognitive therapy will improve cognitive function in patients…
- Trial name
- TRAINS (NCT04897334)
- Testing
- tDCS, Cognitive Therapy
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Pennsylvania
Ischemic Stroke
The Correlation Between Outcome and Infarct Growth in Patients With Acute Ischemic Stroke
Previous research has shown there wasn't inevitable relationship between mismatch area and infarct growth according to Volumetric-subtraction mismatch volume.The recently published on Stroke paper has proposed Coregistration…
- Trial name
- COIG (NCT01376609)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Acute Non-cardioembolic Ischemic Stroke
Study to Gather Information About Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following a Recent Non Cardioembolic Ischemic Stroke Which Occurs When a Blood Clot Has Formed Somewhere in the Human Body (But Not in the Heart) Travelled to the Brain.
The purpose of this study is to try to find the best dose of the new drug BAY 2433334 to give to participants and to look at how well BAY 2433334 works on top of antiplatelet therapy in patients following a recent non…
- Trial name
- PACIFIC-STROKE (NCT04304508)
- Testing
- BAY2433334
- Where
- 197 sites in United States, Australia and 21 more
- Volunteers
- 1,808 people
- Sponsor
- Bayer
Ischemic Stroke, Hemorrhagic Stroke
Safety of Autologous M2 Macrophage in Treatment of Non-Acute Stroke Patients
The purpose of this study is to determine whether M2 macrophages are safe and feasible in the treatment of non-acute stroke patients
- Trial name
- NCT01845350
- Testing
- M2 macrophage introduction
- Where
- Russia
- Volunteers
- 13 people
- Sponsor
- Siberian Branch of the Russian Academy of Medical Sciences
Ischemic Stroke, Neuroprotection
Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With No Reperfusion Therapy (INSIST-NRT)
To explore the safety and feasibility of intra-arterial neuroprotective strategy in acute ischemic stroke patients who missed recanalization operation.
- Trial name
- NCT04664946
- Testing
- Intra-arterial administration of neuroprotective agents
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Hui-Sheng Chen
Hypothermia
Pharmacokinetics of Ampicillin in Neonates With Moderate to Severe Hypoxic-Ischemic Encephalopathy
Controlled Hypothermia has become the standard of care for neonates with moderate to severe HIE. Ampicillin and aminoglycosides are drugs that are universally used for the treatment of suspected neonatal sepsis, which may or may…
- Trial name
- NCT03129620
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Drexel University
Hypothermia, Stroke, Acute
Short-duration Selective Brain Cooling for Patients Undergoing Mechanical Thrombectomy
To determine the efficacy and safety of short-duration intra-artery selective brain cooling in addition to mechanical thrombectomy in patients with acute ischemic stroke.
- Trial name
- NCT03163459
- Testing
- selective brain cooling by cold saline perfusion, mechanical thrombectomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Ali Pay Intelligent Navigation Applet-aided Pre-hospital Triage for Non-emergency Medical Service Patients With Acute Ischemic Stroke
According to the Bigdata Observatory platform for Stroke of China (BOSC), the proportion of patients with acute ischemic stroke (AIS) receiving intravenous thrombolysis or endovascular treatment in China is 5.64% and 1.45%…
- Trial name
- i-Path (NCT06613074)
- Testing
- Ali Pay intelligent navigation applet
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Hemiparesis
Mechanisms of Arm Recovery in Stroke Patients With Hand Paralysis
This study examines the effect of non-invasive brain stimulation targeting different brain areas on movement of the affected arm post-stroke.
- Conditions
- Stroke, Hemiparesis, Cerebral Vascular Accident, Stroke, Ischemic
- Trial name
- NCT03067818
- Testing
- Unaffected Transcranial Magnetic Stimulation, Affected Transcranial Magnetic Stimulation, Control Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- George Mason University
Acute Ischemic Stroke
Multi-arm Optimization of Stroke Thrombolysis
The primary efficacy objective of the MOST trial is to determine if argatroban (100µg/kg bolus followed by 3µg/kg per minute for 12 hours) or eptifibatide (135µg/kg bolus followed by 0.75µg/kg/min infusion for two hours) results…
- Trial name
- MOST (NCT03735979)
- Testing
- Argatroban, Eptifibatide
- Where
- 61 sites in United States
- Volunteers
- 514 people
- Sponsor
- Washington University School of Medicine
Stroke
Acute Stroke Advancing Program Using Telemedicine
The purpose is to evaluate the effectiveness and safety profile of telemedicine consultation system in making decision on IV thrombolysis.
- Trial name
- ASAP-Tel (NCT02088346)
- Testing
- Telemedicine consultation system
- Where
- 4 sites in China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Acute Ischemic Stroke, Biofeedback
Effects of Biofeedback in Patients With Acute Cerebral Infarction
The major aim of this study is to investigate the effects of biofeedback assisted abdominal breathing training on improving the psychological and physiological distress in patients with ACI.
- Conditions
- Acute Ischemic Stroke, Biofeedback, Autonomic Dysfunction, Cognitive Function, Psychological Distress
- Trial name
- NCT03516227
- Testing
- heart rate variability biofeedback
- Volunteers
- 40 people
- Sponsor
- National Defense Medical Center, Taiwan
Stroke
Fangshan / Family-based Ischemic Stroke Study In China
The exact etiology of ischemic stroke remains unclear, because multiple genetic predispositions and environmental risk factors may be involved, and their interactions dictate the complexity.
- Trial name
- FISSIC (NCT00534742)
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Peking University
Stroke, Ischemic
Rehabilitation Program Dedicated to Post-stroke Lateropulsion Including Exoskeleton Assisted Exercises
Lateropulsion is a deficit in the body orientation with respect to the vertical in the coronal plane, defined by the presence of one of the three signs: lateral body tilt, active pushing from the sound limbs, and resistance to…
- Trial name
- EXOLAT (NCT07023770)
- Testing
- specific lateropulsion rehabilitation program (exoskeleton + specific physiotherapy orientation rehabilitation), Conventional physiotherapy without without exercises dedicated to lateropulsion or verticality representation alleviation
- Where
- 2 sites in France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Grenoble
Acquired Brain Injury
Effect of Methylphenidate on Ecologic Function in Paediatric Acquired Brain Injury Population
The purpose of this study is to investigate the influence of Methylphenidate in pediatric acquired brain injury population, regarding ecologic (every day) function.
- Trial name
- NCT02227056
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Loewenstein Hospital
Ischemic Stroke
Study for the Use of Alteplase in Patients Who Awaken With Stroke
This is a pilot study of thrombolytic therapy in patients with ischemic stroke who present with stroke symptoms upon awakening.
- Trial name
- AWOKE (NCT01150266)
- Testing
- Alteplase (tPA)
- Where
- United States
- Sponsor
- University of California, San Diego
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.