Clinical trials: Ischemia, Myocardial
Coronary Artery Disease, Valvular Heart Disease
Effect of Topical Anesthesia on Hemodynamics During the Induction Period in Patients Undergo Cardiac Surgery.
The aim of the induction is to decrease stress response of endotracheal intubation. It is also important to keep hemodynamics stable during and after the induction period.
- Conditions
- Coronary Artery Disease, Valvular Heart Disease, Arrhythmia, Myocardial Disease
- Trial name
- NCT04744480
- Testing
- The combined topical anesthesia induction group
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Qianfoshan Hospital
Coronary Artery Disease, Valvular Heart Disease
Prognostic Value of Lung Ultrasound in Predicting Intensive Care Unit Length of Stay in Adult Cardiac Surgery
Being easy, bedside, non-expensive, noninvasive and radiation free, there has been a growing interest in the implementation of lung ultrasound in critical care management in the last decade, cardiac surgery was not an exception…
- Trial name
- NCT04499027
- Testing
- Lung ultrasound scan
- Where
- Egypt
- Volunteers
- 191 people
- Sponsor
- Fayoum University Hospital
Myocardial Infarction, Acute, Heart Failure, Left Sided
Study to Assess Efficacy and Safety of CDR132L in Patients With Reduced Left Ventricular Ejection Fraction After Myocardial Infarction
This is a Phase 2, multicenter, randomized, parallel, 3-arm, placebo-controlled study to assess efficacy and safety of CDR132L in patients with reduced Left Ventricular Ejection Fraction (LVEF) (≤ 45%) after myocardial infarction…
- Trial name
- HF-REVERT (NCT05350969)
- Testing
- CDR132L
- Where
- 49 sites in Czechia, Germany and 6 more
- Volunteers
- 294 people
- Sponsor
- Cardior Pharmaceuticals GmbH
Coronary Artery Disease, Multi Vessel Coronary Artery Disease
Influence of Risk Factors on ISR and Nonintervened Lesions
This study enrolled patients who used to received PCI therapy with nonintervened coronary lesions. Baseline characteristics and laboratory testing were collected to find out the risk factor difference between ISR and…
- Trial name
- NCT06039059
- Where
- China
- Volunteers
- 510 people
- Sponsor
- RenJi Hospital
Coronary Artery Disease, Valvular Heart Disease
Sugammadex Titration in Cardiac Surgery Patients
Sugammadex is frequently used to reverse the effects of neuromuscular blocking drugs. The recommended doses are 2 mg/kg or 4 mg/kg depending upon the depth of neuromuscular blockade.
- Conditions
- Coronary Artery Disease, Valvular Heart Disease, Aorta Disease, Heart Failure
- Trial name
- NCT05246397
- Testing
- Sugammadex administration
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Valvular Disease, Coronary Stenosis
The Scanner in the Coronary Evaluation
Conventional coronary angiography is the recommended procedure in detection of coronary stenosis in patients with heart valve disease referred for surgery.The aim of this prospective study is to assess diagnostic accuracy of…
- Trial name
- NCT00484380
- Testing
- Coronary scanner
- Where
- France
- Volunteers
- 66 people
- Sponsor
- French Cardiology Society
Coronary Artery Disease
Temperature and Analgesia Monitoring During Cardial Parmonary Bypass
1. Investigator will apply IOC2 to reflect the depth of analgesic during hypothermia in CPB period. 2. effectiveness of IOC2 monitoring for anesthetic depth versus commonly used vital sign monitoring based on factors such as…
- Trial name
- NCT03358680
- Testing
- noninvasive analgesia measurement
- Where
- China
- Volunteers
- 39 people
- Sponsor
- China International Neuroscience Institution
Coronary Heart Disease
Motivational Interviewing and Medication Review in Coronary Heart Disease
Low medication adherence in patients with coronary heart disease increases mortality. This study investigates if an intervention of medication review and counselling can improve patients' medication adherence and treatment…
- Trial name
- MIMeRiC (NCT02102503)
- Testing
- Standard Treatment, MI and Medication review
- Where
- Sweden
- Volunteers
- 417 people
- Sponsor
- Göran Petersson
Coronary Artery Disease, Congestive Heart Failure
Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO)
The purpose of this study is to investigate the safety of intracoronary cardiac stem cells (CSCs) therapy in humans. Currently, there is no effective intervention to regenerate (regrow) dead heart muscle after a heart attack.
- Trial name
- SCIPIO (NCT00474461)
- Testing
- Treatment group
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Louisville
Coronary Artery Disease
Compare the Safety and Efficacy of Genoss® DCB and SeQuent® Please NEO in Korean Patients With Coronary De Novo Lesions
The purpose of this study is to evaluate the safety and efficacy of a novel Paclitaxel-coated balloon (Genoss® DCB) by demonstrating non-inferiority to in-lesion late lumen loss at 6 months after the procedure in Korean patients…
- Trial name
- NCT05096442
- Testing
- GENOSS® DCB, SeQuent® Please NEO
- Where
- South Korea
- Volunteers
- 204 people
- Sponsor
- Genoss Co., Ltd.
Secondary Prevention of Coronary Heart Disease
The Gentle Cardiac Rehabilitation Study
The purpose of this study is to develop a tai-chi based exercise program designed for patients who recently had a heart attack and do not wish, or are unable, to attend traditional cardiac rehabilitation.
- Trial name
- NCT02165254
- Testing
- PLUS, LITE
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- The Miriam Hospital
Anesthesia, Local, Coronary Artery Disease
Local Anesthesia in Radial Catheterization
A randomized clinical trial to test the efficacy of EMLA cream (lidocaine 2.5% and prilocaine 2.5% in a ratio of 1:1 by weight) in comparison to the established local anesthesia (LA) protocol of lidocaine subcutaneous injection…
- Conditions
- Anesthesia, Local, Coronary Artery Disease, Catheter Site Discomfort, Catheter Site Pain
- Trial name
- RAOLA (NCT03072394)
- Testing
- Local anesthetic, local anaesthetic injection
- Where
- Greece
- Volunteers
- 444 people
- Sponsor
- Hippocration General Hospital
ST-elevation Myocardial Infarction
Intracoronary Cocktail Injection Combined With Thrombus Aspiration in STEMI Patients Treated With Primary Angioplasty
This is a randomized, double blind, placebo controlled study of intracoronary cocktail injection combined with thrombus aspiration versus thrombus aspiration alone in ST-elevation myocardial infarction patients treated with…
- Trial name
- NCT02592694
- Testing
- cocktail, thrombus aspiration
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xijing Hospital
Medication Adherence, Myocardial Infarction
A Nursing Intervention Program to Improve Therapeutic Adherence in Elderly People With Acute Myocardial Infarction
The objective of this study was to assess the impact of a nursing intervention on therapeutic adherence in elderly patients after acute myocardial infarction compared to a control group
- Trial name
- NCT04662762
- Testing
- Nursing intervention programme
- Volunteers
- 160 people
- Sponsor
- Hospital Universitari de Bellvitge
STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI
Dutch Cangrelor Registry
Cangrelor is a fast and directly acting platelet aggregation inhibitor. It is potentially indicated for several types of patients who are undergoing PCI.
- Conditions
- STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI, Coronary Artery Disease
- Trial name
- NCT04138641
- Testing
- Cangrelor
- Where
- Netherlands
- Volunteers
- 250 people
- Sponsor
- Isala
Thrombosis, Atherothrombosis
In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer
To date, the investigators have successfully employed a radiotracer (18F-sodium fluoride) as a marker of necrotic inflammation in human atherosclerosis.
- Conditions
- Thrombosis, Atherothrombosis, Myocardial Infarction, STEMI
- Trial name
- iThrombus (NCT03943966)
- Testing
- 18F-GP1 PET CT
- Where
- United Kingdom
- Volunteers
- 73 people
- Sponsor
- University of Edinburgh
Antiplatelet Drug, Acute Coronary Syndrome
1-month DAPT Plus 5-month Ticagrelor Monotherapy Versus 12-month DAPT in Patients With Drug-coated Balloon
Drug-Coated Balloon (DCB) angioplasty is similar to plain old balloon angioplasty procedurally, but there is an anti-proliferative medication paclitaxel coated to the balloon.
- Conditions
- Antiplatelet Drug, Acute Coronary Syndrome, Angioplasty, Balloon
- Trial name
- CAGEFREEII (NCT04971356)
- Testing
- Aspirin 100mg for 1-month (immediately after PCI), Ticagrelor 90mg for 6-month (immediately after PCI), Aspirin 100mg for 6-month (6-month post PCI)
- Where
- China
- Volunteers
- 1,948 people
- Sponsor
- Xijing Hospital
Coronary Arteriosclerosis
EARly Prevention of aTHeroma Progression
The purpose of this study is to compare standard therapy (risk factor control, life style modification) versus standard therapy plus low-dose rosuvastatin therapy (5mg/day) on progression of coronary atherosclerosis in statin…
- Trial name
- EARTH (NCT02105623)
- Testing
- Standard Therapy, Rosuvastatin
- Where
- South Korea
- Volunteers
- 111 people
- Sponsor
- CHEOL WHAN LEE, M.D., Ph.D
Coronary Arteriosclerosis, Angina Unstable
Stents, Drug Eluting Stents, and CABG- Financial and Clinical Impact.
Options for coronary revascularization include stent implantation and coronary bypass surgery. Both modalities have their unique advantages and disadvantages in terms of clinical outcomes as well as financial impact on the…
- Conditions
- Coronary Arteriosclerosis, Angina Unstable, Myocardial Infarction
- Trial name
- NCT00394680
- Volunteers
- 700 people
- Sponsor
- Shaare Zedek Medical Center
ST-elevation Myocardial Infarction (STEMI)
The Impact of Post Stenting Balloon Dilatation on Coronary Microcirculation in STEMI Patients Undergoing PPCI
This study aims to assess the impact of NC balloon post-dilatation on coronary microcirculation in patients with ST segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI).
- Trial name
- POSTDILSTEMI (NCT02788396)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
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