Clinical trials: Ischemia, Myocardial
Diabetes Mellitus, Type 2, Heart Failure
Randomised Trial of Health Coaching in Secondary Prevention of Diabetes and Heart Disease
A randomised trial with individual patients as units of observation will be carried out. Health coaching is used to modify health behaviour and thus improve disease control and health status, as well as use of health care…
- Conditions
- Diabetes Mellitus, Type 2, Heart Failure, Coronary Disease
- Trial name
- TerVa (NCT00552903)
- Testing
- Health coaching
- Where
- Finland
- Volunteers
- 1,500 people
- Sponsor
- Paijat-Hame Hospital District
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)
Study of heterogeneity in associations between heart rate and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Coronary Death, Intracerebral Haemorrhage
- Trial name
- NCT01947361
- Where
- United Kingdom
- Volunteers
- 1,961,286 people, healthy volunteers welcome
- Sponsor
- University College, London
Refractory Angina
Intramyocardial Delivery of Autologous Bone Marrow
A randomized study to assess the safety, feasibility and effectiveness of direct intramyocardial percutaneous delivery of autologous bone marrow-derived total mononuclear cells or selected CD34+ cells in patients with refractory…
- Trial name
- NCT00820586
- Testing
- Mononuclear bone marrow derived cells
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- IRCCS San Raffaele
Coronary Artery Disease, Cardiac Rehabilitation
Electronic Cardiac Rehabilitation (eCardiacRehab) Feasibility Study
In Norway, more than 11,000 patients undergo percutaneous coronary intervention (PCI) annually. However, a very recent study utilizing registry data show a national average of cardiac rehabilitation (CR) participation of only…
- Conditions
- Coronary Artery Disease, Cardiac Rehabilitation, Ethics, Continuity of Patient Care
- Trial name
- eCardiacRehab (NCT06759805)
- Testing
- eCardiacRehab
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Haukeland University Hospital
Atherosclerosis, Coronary Artery Disease
National Plaque Registry and Database
The ultimate goal of this project is to develop a risk score to identify patients with vulnerable coronary atherosclerotic plaques, who are prone to suffer acute coronary syndrome.
- Conditions
- Atherosclerosis, Coronary Artery Disease, Cardiovascular Disease
- Trial name
- OPeRA (NCT02578355)
- Where
- 11 sites in Hungary
- Volunteers
- 20,000 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Coronary Disease
RE-DEEM Dose Finding Study for Dabigatran Etexilate in Patients With Acute Coronary Syndrome
The purpose of this trial is to evaluate the safety and indicators of efficacy of up to 4 doses of orally administered dabigatran etexilate, administered twice daily, compared to placebo when given in addition to dual…
- Trial name
- NCT00621855
- Testing
- dabigatran etexilate
- Where
- 167 sites in United States, Belgium and 22 more
- Volunteers
- 1,878 people
- Sponsor
- Boehringer Ingelheim
Coronary Artery Disease, Diabetes Mellitus
Study Design of 'Influence of Sarpogrelate in Patients With Renal Impairment or Diabetes Mellitus' Study
The purpose of the SERENADE trial is to evaluate the safety and efficacy of sarpogrelate in patients with CKD or DM after DES implantation.
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Renal Insufficiency, Chronic
- Trial name
- SERENADE (NCT02294643)
- Testing
- Sarpogrelate, Aspirin, Clopidogrel
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Seoul National University Bundang Hospital
Myocardial Ischemia, Heart Failure, Congestive
Stem Cell Therapy in Chronic Ischemic Heart Failure
The purpose of this study is to determine whether intracoronary bone marrow transplantation can improve left ventricular ejection fraction in patients with severe ischemic heart failure and no other option for standard therapies…
- Trial name
- NCT00235417
- Testing
- Bone marrow transplantation
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Odense University Hospital
Coronary Artery Disease, Acute Coronary Syndrome
Τicagrelor Versus Prasugrel in Diabetic Patients: a Pharmacodynamic Study
This is a prospective, randomized, single-center, single blind, investigator initiated, two period study of crossover design. Diabetic patients with Acute Coronary Syndrome (ACS), treated with oral and/or parenteral hypoglycaemic…
- Trial name
- NCT01642940
- Testing
- Prasugrel, Ticagrelor
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- University of Patras
Coronary Artery Disease
A Phase I Study to Evaluate BFPET as a Potential Myocardial Perfusion Imaging(MPI) Agent for PET
Safety and dosimetry of BFPET™ will be evaluated in healthy volunteers and Coronary Artery Disease (CAD) patients , male or female and of age ranging between 20-80 years old.
- Trial name
- NCT00733460
- Testing
- BFPET
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fluoropharma, Inc.
Cardiovascular Diseases, Coronary Aneurysm
Prevention of Coronary Aneurysms in Kawasaki Syndrome
To test the efficacy of intravenous gamma globulin (IVGG) in preventing coronary artery aneurysms in children with Kawasaki Syndrome.
- Conditions
- Cardiovascular Diseases, Coronary Aneurysm, Heart Diseases, Mucocutaneous Lymph Node Syndrome
- Trial name
- NCT00000520
- Testing
- immunoglobulins, intravenous, aspirin
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pregnancy, Pulmonary Embolism
Identify Clinical Conditions That Increase Circulating DNA Levels
The investigators are developing a test that is expected to measure the amount of radiation a patient has been exposed to after a nuclear bomb.
- Conditions
- Pregnancy, Pulmonary Embolism, Myocardial Infarction, Autoimmune Disease
- Trial name
- BARDA II (NCT01815996)
- Testing
- One time blood draw to look at patient's DNA
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Florida
Myocardial Infarction, Cardiovascular Death
Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin
This study is being carried out to see if a new drug called ticagrelor given twice daily in addition to the ASA therapy decreases the frequency of cardiovascular events (e.g., death from heart disease, heart attack, or stroke).
- Conditions
- Myocardial Infarction, Cardiovascular Death, Atherothrombosis, Stroke
- Trial name
- PEGASUS (NCT01225562)
- Testing
- Ticagrelor 90 mg, Ticagrelor 60 mg
- Where
- 826 sites in United States, Argentina and 29 more
- Volunteers
- 21,379 people
- Sponsor
- AstraZeneca
Coronary Artery Disease, ST Elevation Myocardial Infarction
Prognostic Implications of AccuFFRangio-guided PCI in STEMI
This is a prospective, single-center clinical trial. AccuFFRangio (ArteryFlow Technology Co., Ltd., Hangzhou, China) is a novel method for evaluating the functional significance of coronary stenosis by computing the pressure in…
- Trial name
- NCT05209503
- Testing
- AccuFFRangio-guided strategy, Angiography-guided strategy
- Volunteers
- 500 people
- Sponsor
- Wuhan Asia Heart Hospital
Myocardial Infarction
A Study to Evaluate the Use of Mobile-phone Based Patient Support in Patients Diagnosed With Myocardial Infarction
The purpose of this study is to evaluate whether the mobile-phone based patient support has an impact on the adherence and persistence of ticagrelor treatment or on lifestyle changes that will have a positive impact on the…
- Trial name
- SUPPORT (NCT01874262)
- Testing
- Mobile-phone based patient support, e-diary
- Where
- 13 sites in Sweden
- Volunteers
- 174 people
- Sponsor
- AstraZeneca
Acute Coronary Syndromes, STEMI
Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary Syndrome
This is a prospective, open-label, multicenter, randomized, phase IV clinical trial designed to evaluate the safety and efficacy of early aspirin discontinuation followed by potent P2Y12 inhibitor monotherapy after intravascular…
- Conditions
- Acute Coronary Syndromes, STEMI, NSTEMI, Unstable Angina
- Trial name
- SAPT-ACS (NCT07684742)
- Testing
- Early P2Y12 Inhibitor Monotherapy, Standard Dual Antiplatelet Therapy
- Where
- South Korea
- Volunteers
- 1,900 people
- Sponsor
- Gyeongsang National University Hospital
Coronary Heart Disease
Exercise-based Telerehabilitation in the Cardiac Rehabilitation Program
The intervention will involve a system that comprises a wrist-worn activity tracker and a smartphone app that acts as a medium to link to the healthcare website
- Trial name
- NCT04330560
- Testing
- Exercise telemonitoring connects to healthcare platform, Exercise self-monitoring, Exercise teleconsultation
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- University of Malaya
Myocardial Infarction, STEMI
The Effect of 12 Lead ECG Telemetry on Reperfusion Time in Resource-limited Settings
This study aims to determine whether prehospital 12 lead ECG telemetry decreases the time to reperfusion in patients presenting with STEMI.
- Trial name
- NCT02441582
- Testing
- Telemetry, Non-telemetry
- Where
- 2 sites in South Africa
- Volunteers
- 19 people
- Sponsor
- Karolinska Institutet
ST-segment Elevation Myocardial Infarction (STEMI)
The Prognostic Value of Anion Gap in Predicting Major Adverse Cardiovascular Events Among Patients With ST-Segment Elevation Myocardial Infarction
This study aims to evaluate the prognostic value of the anion gap in predicting major adverse cardiovascular events among patients with ST-segment elevation myocardial infarction.
- Trial name
- ANGIO-STEMI (NCT06586424)
- Testing
- Anion gap
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Diponegoro
Cardiogenic Shock
Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)
Extracorporeal membrane oxygenation (ECMO) is of great value in supporting patients with cardiac shock. More than 80% ECMO patients will develop renal catastrophe that continuous renal replacement therapy (CRRT) is required.
- Trial name
- ELITE (NCT03549923)
- Testing
- Simultaneous CRRT, Conventional-indication CRRT, Esmolol
- Where
- China
- Volunteers
- 131 people
- Sponsor
- Beijing Anzhen Hospital
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