Clinical trials: Ischemia Preconditioning
Intermittent Claudication, Ischemia Vascular
Ischemic Preconditioning Claudication Study
This study proposes ischemic preconditioning (IPC) as a novel intervention to improve walking distance in patients with intermittent claudication.
- Conditions
- Intermittent Claudication, Ischemia Vascular, Peripheral Arterial Disease, Peripheral Vascular Disease
- Trial name
- NCT03511157
- Testing
- Ischemic Preconditioning, Control Group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Medical College of Wisconsin
Ischemia Reperfusion Injury
Desflurane Preconditioning in Hepatectomies
Hepatectomies are considered as operations of high bleeding risk. The history of massive hemorrhage in liver surgery led to the emergence of techniques to control excessive blood loss.
- Trial name
- NCT03848780
- Testing
- Desflurane
- Volunteers
- 46 people
- Sponsor
- Aristotle University Of Thessaloniki
Reperfusion Injury
Remote Ischaemic PreConditioning (RIPC) in Partial Nephrectomy for the Prevention of Ischemia/Reperfusion Injury
"Remote Ischaemic PreConditioning" (RIPC) is performed prior to partial nephrectomy. Postoperative calprotectin dynamics and Blood Oxygen-Level-Dependent (BOLD) MRI are used to to demonstrate the potential renoprotective effect…
- Trial name
- NCT03068689
- Testing
- RIPC
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Ischemic Preconditioning, Coenzyme Q Deficiency
Effect of CoQ10 on the Endocrine Function of Skeletal Muscle
Recent studies have also shown that repeated episodes of ischemia, followed by reperfusion (IPC), can contribute to the development of adaptive changes not only in the area of the heart muscle, but also in the structure of the…
- Conditions
- Ischemic Preconditioning, Coenzyme Q Deficiency, Exercise Training
- Trial name
- NCT05412888
- Testing
- CoQ10 supplementation, Ischemic preconditioning training, IPC training combined with CoQ10 supplementation
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Myocardial Injury
Effect of Delayed Remote Ischemic Preconditioning on Myocardial Injury
The purpose of this study is to evaluate delayed myocardial protective effect of RIPC in patients undergoing cardiac valve replacement surgery.
- Trial name
- RIPC (NCT01903161)
- Testing
- delayed remote ischemic preconditioning, control
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Seoul National University Hospital
Ischemia Reperfusion Injury
Remote Ischemic Preconditioning in Cardiac Surgery
Aim of the work : Evaluation of the role of Remote Ischemic Preconditioning (RIP) on liver function in patients undergoing on-pump cardiac surgery.
- Trial name
- NCT04647370
- Testing
- remote ischemic preconditioning
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Contrast Induced Acute Kidney Injury
The Effect of Remote Ischemic Preconditioning on Elective Percutaneous Coronary Intervention in Diabetic Nephropathy
Contrast-induced acute kidney injury (CI-AKI) is a significant iatrogenic complication of contrast media use associated with prolonged hospitalization, cardiovascular events, persistent kidney damage and increased risk of…
- Trial name
- NCT02329444
- Testing
- Remote ischemic preconditioning
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ulsan University Hospital
Peripheral Vascular Disease
RCT to Evaluate the Renal Protective Effects of Remote Ischaemic Preconditioning in Peripheral Angioplasty
This study aims to demonstrate if remote ischaemic preconditioning (RIPC) may confer renal protection in patients undergoing peripheral angioplasty.
- Trial name
- NCT02054871
- Testing
- RIPC
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mid Western Regional Hospital, Ireland
Coronary Artery Disease
TEAM-Project: Trial on the Effect of Anesthetics on Morbidity and Mortality
Volatile anesthetics may provide some protection from myocardial ischemia, an effect called anesthetic preconditioning. In patients undergoing coronary artery bypass surgery, this preconditioning effect resulted in better cardiac…
- Trial name
- NCT00286585
- Testing
- Inhalational anesthetic, Intravenous anesthetic, propofol
- Where
- 3 sites in Switzerland
- Volunteers
- 385 people
- Sponsor
- University Hospital, Basel, Switzerland
Cardiopulmonary Bypass, Cardiovascular Diseases
Protective Effect of RIPC Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Surgery (Panda VII)
Remote ischaemic pre-conditioning (RIPC) has been recognized as a low-cost, non-invasive intervention method by applying brief ischaemia and reperfusion on an arm or a leg.
- Conditions
- Cardiopulmonary Bypass, Cardiovascular Diseases, Inflammatory Response During Cardiac Surgery
- Trial name
- PANDA (NCT06707350)
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Aortic Valve Stenosis, Renal Insufficiency
Remote Ischemic Preconditioning for Renal Protection in TAVI
Severe aortic stenosis remains a major cause of morbidity and mortality of the elderly affecting approximately 3% of elderly patients with an increasing number of patients undergoing transcatheter aortic valve interventions.
- Conditions
- Aortic Valve Stenosis, Renal Insufficiency, Contrast-induced Nephropathy
- Trial name
- NCT03347032
- Testing
- Remote ischemic preconditioning, Control
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Henry Ford Health System
Myocardial Ischemia, Ischemic Reperfusion Injury
Remote Ischemic Preconditioning in Elective Percutaneous Interventions
Myocardial injury occurs after percutaneous coronary intervention due to micro emboli, ischemia-reperfusion injury or side branch occlusion.
- Trial name
- NCT02581618
- Testing
- remote ischemic preconditioning
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Trakya University
Coronary Artery Disease, Valvular Heart Disease
Application of Remote Ischemic Preconditioning in Patients Undergoing Open Heart Surgeries
Strategies for myocardial protection during open heart surgeries are desired. Several experimental studies have shown beneficial effects of remote ischemic preconditioning (RIPC).
- Trial name
- NCT01906918
- Testing
- IRPC, Remote preconditioning
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Campinas, Brazil
Ischemic Reperfusion Injury, Other Reconstructive Surgery
RIPC During Free Flap With Preoperative Radiotherapy
Remote ischemic preconditioning (RIPC) has shown organ-protective effects in many clinical settings including patients with ischemic heart disease.
- Conditions
- Ischemic Reperfusion Injury, Other Reconstructive Surgery, Radiotherapy
- Trial name
- NCT03535623
- Testing
- remote ischemic preconditioning (RIPC)
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Congenital Heart Disease
Remote Preconditioning and Myocardial Protection
Remote ischemic preconditioning (RIPC) of the myocardium by limb ischemia/reperfusion may mitigate cardiac damage, but its interaction with the anesthetic regimen is unknown.
- Trial name
- NCT02877238
- Testing
- Sevoflurane plus remote ischemic preconditioning, Total intravenous anesthesia plus remote ischemic preconditioning
- Where
- Egypt
- Volunteers
- 91 people
- Sponsor
- Assiut University
Cardiac Surgery Patients
The Neuroprotection of Remote Ischemic Preconditioning (RIPC) on Cardiac Surgery in Multicenter
The current study is designed to clarify the neuroprotective effect of remote ischemic preconditioning on the patients underwent open-heart cardiac surgery.
- Trial name
- NCT01231789
- Testing
- RIPC
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Physical Performance, Rhabdomyolysis
The Effect of Remote Ischemic Preconditioning on Physical Performance and Exertional Rhabdomyolysis
In order to examine the effect of RIPC on skeleton muscle exertional damage and on aerobic and anaerobic physical performances, 30 healthy volunteers will undergo a series of different physical tests twice; once without…
- Trial name
- NCT02518724
- Testing
- RIPC intervention exposure
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Liver Transplant; Complications, Ischemia Reperfusion Injury
The Effect of Remote Ischemic Preconditioning on Ischemia/Reperfusion Injury in a Liver Transplant Recipient
Ischemia and reperfusion injury is unavoidable during a liver transplantation. Remote ischemic preconditioning, a safe and feasible method, has previously been shown to reduce ischemia and reperfusion injury.
- Trial name
- NCT03758352
- Testing
- remote ischemic preconditioning (rIC), non remote ischemic preconditioning (non-rIC)
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Elderly Patients, Non-cardiac Surgery
Effects of Limb Remote Ischemic Preconditioning for Prevention of Delirium in Elderly Patients After Non-cardiac Surgery
To investigate whether limb remote ischemic preconditioning (LRIP) could safely decrease the incidence of delirium in elderly patients after non-cardiac surgery.
- Trial name
- LRIP-D (NCT03028389)
- Testing
- limb remote ischemic preconditioning(LRIP)
- Volunteers
- 611 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Acute Lung Injury
Limb RIPC in Patients Undergoing Lung Lobectomy. Study of Oxidative Lung Damage
Background: In patients undergoing lung lobectomy, lung collapse and re-expansion after resection is associated to severe oxidative lung injury.
- Trial name
- NCT02734654
- Testing
- remote ischemic preconditioning (RIPC)
- Volunteers
- 53 people
- Sponsor
- Instituto de Salud Carlos III