Clinical trials: Ischemic Cardiovascular Disease
Ischemic Heart Disease, Cardiovascular Diseases
Acute Safety, Deliverability and Efficacy of the Medtronic Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System in the Treatment of Suitable Patients According to Indication for Use (CHINA RESOLUTE INTEGRITY STUDY)
The purpose of this study is to conduct a prospective, multi-center, single arm, non-randomized evaluation of acute outcomes in Chinese subjects, including those eligible for percutaneous transluminal coronary angioplasty (PTCA)…
- Conditions
- Ischemic Heart Disease, Cardiovascular Diseases, Arteriosclerosis, Coronary Artery Disease
- Trial name
- NCT02452736
- Testing
- Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System
- Where
- 2 sites in China
- Volunteers
- 205 people
- Sponsor
- Medtronic Vascular
Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy
A Study of Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure
The purpose of this trial is to assess whether MYDICAR can reduce the frequency and/or delay heart failure related hospitalizations in persons with advanced heart failure when added to their maximal and optimized therapy.
- Conditions
- Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy, Heart Failure, Cardiomyopathies
- Trial name
- CUPID-2b (NCT01643330)
- Testing
- AAV1/SERCA2a (MYDICAR)
- Where
- 54 sites in United States, Belgium and 8 more
- Volunteers
- 250 people
- Sponsor
- Celladon Corporation
Cardiovascular Diseases, Heart Diseases
Evans County Studies
To conduct surveillance of cardiovascular morbidity and mortality and its correlation with known risk factors in all cohort study groups in Evans County, Georgia.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Angina Pectoris
- Trial name
- NCT00005122
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Ischemic Stroke, Hypothermia
REperfusion With Cooling in CerebraL Acute IscheMia II
The purpose of this study is to determine whether reducing a patient's body temperature (mild hypothermia of 33 degrees Centigrade) will significantly reduce the risk of brain injury (notably reperfusion injury and hemorrhagic…
- Trial name
- RECCLAIM-II (NCT02411877)
- Testing
- Normothermia, Mild hypothermia, Trevo Pro Retriever (Stryker Corp.)
- Where
- United States
- Sponsor
- WellStar Health System
Hypertension, Dyslipidemia
Improved Delivery of Cardiovascular Care Through Outreach Facilitation
The aim of the proposed study is to implement and evaluate Outreach Facilitation as a means to increase the uptake of evidence-based practice for secondary prevention and management of patients with established CVD and…
- Conditions
- Hypertension, Dyslipidemia, Diabetes, Chronic Kidney Disease
- Trial name
- IDOCC (NCT00574808)
- Testing
- Outreach Facilitation implementing elements of the Chronic Care Model
- Where
- Canada
- Volunteers
- 194 people
- Sponsor
- C. T. Lamont Primary Care Research Centre
Cardiovascular Disease, Ischemic Heart Disease
The Metformin in Coronary Artery Bypass Graft (CABG) (MetCAB) Trial
Rationale: In patients with a myocardial infarction, occlusion of a coronary artery induces myocardial ischemia and cell death. If untreated, the area of myocardium exposed to this interruption in blood supply, will largely…
- Trial name
- MetCAB (NCT01438723)
- Testing
- Metformin
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Cardiovascular Disease, Peripheral Artery Disease
Personalized Cardiovascular Risk Information to Initiate and Maintain Health Behavior Changes
The investigators propose an evaluation that will assess three important components of risk communication: 1. provide patients with personalized risk communication using the risk calculator developed by FIMDM and health…
- Conditions
- Cardiovascular Disease, Peripheral Artery Disease, Ischemic Stroke, Diabetes
- Trial name
- FIMDM_CVD (NCT01134458)
- Testing
- Web-Based Intervention
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Duke University
Ischemic Cardiomyopathy, Chronic Ischemic Cardiomyopathy
REgenerative CardiOsphere iNjection to STRengthen dysfUnCTional Hearts
A double blinded and placebo-controlled, dose escalation, single-center safety and preliminary efficacy study of cardiospheres delivered via NOGA MYOSTAR injection catheter in subjects with chronic ischemic cardiomyopathy.
- Trial name
- RECONSTRUCT (NCT01496209)
- Testing
- Endomyocardial injections of allogeneic Human CSps, Endomyocardial injections of vehicle only.
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Ischemic Heart Disease, Coronary Arteriosclerosis
A Randomized Clinical Trial of Adipose-derived Stem Cells in Treatment of Non Revascularizable Ischemic Myocardium
The purpose of this study is to establish safety and feasibility of utilizing Adipose Derived Stem \& Regenerative Cells (ADRCs) in patients who have areas of myocardium that are not revascularizable and have demonstrated…
- Conditions
- Ischemic Heart Disease, Coronary Arteriosclerosis, Cardiovascular Disease, Coronary Disease
- Trial name
- NCT00426868
- Testing
- Direct injection of ADRCs into the Left Ventricle
- Where
- 4 sites in Denmark, Netherlands and 1 more
- Volunteers
- 27 people
- Sponsor
- Cytori Therapeutics
Chronic Stable Angina, Unstable Angina
The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study
The association between alcohol consumption and cardiovascular disease (CVD) has mostly been examined using broad endpoints or cause-specific mortality.
- Conditions
- Chronic Stable Angina, Unstable Angina, Coronary Heart Disease Not Otherwise Specified, Acute Myocardial Infarction
- Trial name
- NCT01864031
- Where
- United Kingdom
- Volunteers
- 2,240,000 people
- Sponsor
- University College, London
Ischemic Heart Disease
Effectiveness New Health Care Organization Model in Primary Care for Chronic Cardiovascular Disease Patients Based
The purpose of this study is to determine whether a multifactorial primary care intervention based on chronic models can improve the level of control and reduce the number of hospital admissions in patients with ischemic heart…
- Trial name
- PROPRESE (NCT01826929)
- Testing
- Therapeutic education
- Where
- 3 sites in Spain
- Volunteers
- 300 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Heart Diseases, Cardiovascular Diseases
Risk Factors in the Initial Presentation of Specific Cardiovascular Disease Syndromes
Cardiovascular disease (CVD) is an important public health problem that affects millions of people worldwide. Associations between risk factors, such as smoking, dyslipidaemia or hypertension, and prevalent CVD are well…
- Conditions
- Heart Diseases, Cardiovascular Diseases, Acute Myocardial Infarction, Unstable Angina
- Trial name
- NCT01804439
- Volunteers
- 2,240,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Cardiovascular Disease, Ischemic Heart Disease
Can Dipyridamole Induce Protection Against Ischemia and Reperfusion Injury in Patients Undergoing Elective Coronary Artery Bypass Grafting (CABG)?
Rationale: Due to western lifestyle human coronary arteries are prone to develop atherosclerotic plaques. Hence the heart is an important target organ for atherothrombotic complications: myocardial ischemia, arrhythmias…
- Trial name
- NCT01295567
- Testing
- Dipyridamole
- Where
- Netherlands
- Volunteers
- 95 people
- Sponsor
- Radboud University Medical Center
Ischemic Heart Disease, Congestive Heart Failure
Registry of Cardiovascular Disease Patients
A computerized registry of cardiovascular disease patients in a large health maintenance organization in Israel. The registry is aimed to be used by health professionals to identify cardiovascular disease patients and to follow…
- Conditions
- Ischemic Heart Disease, Congestive Heart Failure, Peripheral Vascular Disease, Cerebrovascular Disease
- Trial name
- CVD Registry (NCT01759225)
- Where
- Israel
- Volunteers
- 110,000 people
- Sponsor
- Maccabi Healthcare Services, Israel
Hypertension, Diabetes
New York City (NYC) Health eHearts Pay for Quality Pilot
Do monetary incentives in small independent primary care practices improve the delivery of preventive services as recommended by U.S. Preventive Services Task Force (USPSTF) guidelines for cardiovascular health?
- Conditions
- Hypertension, Diabetes, Smoking, Ischemic Cardiovascular Disease
- Trial name
- ehearts (NCT00884013)
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- New York City Department of Health and Mental Hygiene