Clinical trials: Ischemic Conditioning
Ischemic Cerebrovascular Disease
Limb Remote Ischemic Conditioning and Cerebrovascular Reserve
Cerebrovascular reserve (CVR), defined as the increase in cerebral blood flow (CBF)in response to a vasodilatory stimulus, is known to reflect the compensative capacity of the brain to maintain adequate blood flow in the face of…
- Trial name
- NCT03589053
- Testing
- Limb remote ischemic conditioning, Control group
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Carotid Stenosis, Ischemic Stroke
Remote Ischemic Conditioning and Dynamic Cerebral Autoregulation in Patients With Intracranial and Extracranial Arteriosclerosis
The purpose of this study is to explore the effect of remote ischemic conditioning on the dynamic cerebral autoregulation in patients with intracranial and extracranial arteriosclerosis and the changes of dynamic cerebral…
- Trial name
- NCT05599009
- Testing
- remote ischemic conditioning
- Where
- 2 sites in China
- Volunteers
- 140 people
- Sponsor
- The First Hospital of Jilin University
Aneurysm, Ruptured, Coiling Therapy
The Neuroprotective Effect of Remote Ischemic Conditioning in Ruptured Aneurysm Coiling Therapy
The overall incidence of DWI positive for thromboembolic events following endovascular treatment of intracranial aneurysms is proximately 50%.
- Trial name
- NEAT-2 (NCT03561311)
- Testing
- remote ischemic conditioning
- Where
- 5 sites in China
- Volunteers
- 210 people
- Sponsor
- Capital Medical University
Cerebral Atherosclerosis
Study on Prevention and Treatment of Atherosclerotic Cerebral Occlusive Disease With Remote Ischemic Conditioning
The primary objective of the study will be to determine whether remote limb ischemic conditioning (RLIC) together with conventional medication therapy compared with only medication therapy reduces the 3-month risk of composite…
- Trial name
- NCT04470492
- Testing
- Doctormate®+Medical Management, Medical Management
- Volunteers
- 700 people
- Sponsor
- Ji Xunming,MD,PhD
Diabetic Kidney Disease (DKD)
Remote Ischemic Conditioning for the Treatment of Diabetic Kidney Disease
Chronic kidney disease (CKD) is a growing epidemic affecting 10% of the population worldwide. Significantly, diabetic kidney disease (DKD) is the main cause of CKD and affects approximately 40% of patients with diabetes.
- Trial name
- RIC-DKD (NCT06654921)
- Testing
- Remote ischemic conditioning, Standard medication therapy
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
ASCVD
The Long-term Effect of Remote Ischemic Conditioning on Main Organs in ASVCD Patients With Very High Risks
Atherosclerotic cardiovascular disease (ASCVD) is a group of disorders sharing atherosclerosis as a common pathological basis, primarily affecting the heart, brain, kidneys, and other peripheral arteries, leading to clinical…
- Trial name
- NCT07270887
- Testing
- remote ischemic conditioning
- Where
- China
- Volunteers
- 2,800 people
- Sponsor
- General Hospital of Shenyang Military Region
Myocardial Infarction
Post Conditioning in PCI for Acute ST Elevation Myocardial Infarction
The purpose of this trial is to compare post-conditioning to standard angioplasty (50/50 chance) in patients who present with an acute heart attack and are taken directly for an angioplasty procedure.
- Trial name
- NCT00334373
- Testing
- Post conditioning
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- University of Calgary
Carotid Artery Occlusion
Safety and Efficacy of Remote Ischemic Conditioning in Patients with Chronic Internal Carotid Artery Occlusion Receiving Hybird Surgery: a Pilot, Randomized Controlled Trial
The purpose of this study is to explore the safety and efficacy of remote ischemic conditioning in patients with internal carotid artery occlusion receiving hybird surgery.
- Trial name
- SERIC-HS (NCT06702644)
- Testing
- Remote ischemic conditioning
- Volunteers
- 60 people
- Sponsor
- Yi Yang
Necrotizing Enterocolitis
RIC-NEC Randomized Controlled Trial
Necrotizing enterocolitis (NEC) is a serious intestinal disease of preterm and term neonates which remains a major cause of intestinal failure, and an unsolved clinical challenge in pediatrics.
- Trial name
- RIC-NEC (NCT05279664)
- Testing
- Remote ischemic conditioning (RIC) + Standard of Care for NEC, Standard of Care for NEC
- Where
- 4 sites in United States, Canada
- Volunteers
- 86 people
- Sponsor
- The Hospital for Sick Children
Stroke
Augmenting Cerebral Blood Flow in Acute Ischemic Stroke
The most common type of stroke is ischemic (lack of blood flow to the brain due to a clot blocking a blood vessel). Time is brain and an average of 1.9 million brain nerve cells per minute are destroyed in patients experiencing a…
- Trial name
- NCT06911385
- Testing
- Arm Remote Ischemic Conditioning plus Pneumatic Compression lower limb
- Volunteers
- 150 people
- Sponsor
- University of Alberta
Stroke
Ischemic Conditioning Chronic Stroke Study
Stroke is the leading cause of disability in adults in the United States. Despite advances in hyperacute stroke care, advancements in stroke rehabilitation are lagging.
- Trial name
- NCT04039399
- Testing
- Ischemic Conditioning
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Medical College of Wisconsin
Intracerebral Hemorrhage, Acute Stroke
Remote Ischemic Conditioning for the Treatment of Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) results from the rupture of small vessels damaged by chronic hypertension, amyloid angiopathy or other disease. Currently, ICH has been a devastating type of stroke that lacking effective therapy.
- Trial name
- RICH-2 (NCT04657133)
- Testing
- Remote ischemic conditioning, Standard medication therapy
- Where
- 13 sites in China
- Volunteers
- 452 people
- Sponsor
- Capital Medical University
Carotid Stenosis
Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery Stenosis
Remote ischemic conditioning (RIC) has emerged as a promising non-invasive strategy to protect the brain, with evidence suggesting its benefit in patients with carotid artery stenting (CAS).
- Trial name
- RICSICAS (NCT07412249)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 300 people
- Sponsor
- General Hospital of Shenyang Military Region
Stroke, Fatigue
Remote Ischaemic Conditioning for Fatigue After Stroke 2 (RICFAST 2)
Post-stroke fatigue is an overwhelming tiredness or lack of energy that does not get better with rest. It affects around half of people who have had a stroke.
- Trial name
- RICFAST 2 (NCT07914647)
- Testing
- Remote ischaemic conditioning
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Cerebral Small Vessel Diseases
Effects of Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation, Blood Pressure and Heart Rate Variability in Patients With Cerebral Small Vessel Disease
The purpose of this study is to determine effects of remote ischemic conditioning on dynamic cerebral autoregulation, blood pressure and heart rate variability in patients with cerebral small vessel disease.
- Trial name
- ESCAPE-SVD (NCT05225948)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yi Yang
Aneurysm
The Neuroprotective Effect of Remote Ischemic Conditioning in Aneurysm Coiling Therapy
The overall incidence of DWI positive for thromboembolic events following endovascular treatment of intracranial aneurysms is proximately 50%.
- Trial name
- NEAT (NCT03496415)
- Testing
- remote ischemic conditioning
- Where
- 6 sites in China
- Volunteers
- 210 people
- Sponsor
- Capital Medical University
Ischaemic Heart Diseases
Loop Isolation-based Uploading Pre-conditioning
Myocardial protection is of crucial importance for surgical coronary revascularization in patients with ischaemic heart diseases.
- Trial name
- NCT03766529
- Testing
- loop isolation-based uploading preconditioning (LiuPhD)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing Medical University
Vascular Dementia, Cerebral Small Vessel Diseases
Trial of Remote Ischemic Pre-conditioning in Vascular Cognitive Impairment
Cerebral small vessel disease is a common cause of cognitive impairment. Remote ischemic pre-conditioning (RIC) is a technique to induce brief periods of limb ischemia-reperfusion that is hypothesized to increase tolerance of the…
- Conditions
- Vascular Dementia, Cerebral Small Vessel Diseases, Cerebral Small Vessel Ischaemic Disease, Vascular Cognitive Impairment
- Trial name
- TRIC-VCI (NCT04109963)
- Testing
- Remote ischemic conditioning
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Exercise-induced Muscle Damage
The Effect of Ischemic Pre-Conditioning on the Rate of Recovery Following Exercise-Induced Muscle Damage
Strenuous exercise or exercise involving eccentric muscle contractions can lead to muscle damage and changes in muscle function; this is known as exercise-induced muscle damage (EIMD).
- Trial name
- NCT01907841
- Testing
- Ischemic Preconditioning
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Acute Ischemic Stroke
Safety and Efficacy of Remote Ischemic Conditioning in Patients With Severe Stenosis or Occlusion of Anterior Intracranial Circulation Vessels
The primary purpose of this study is to examine whether remote ischemic treatment can better the 90 - day neurological outcomes in acute ischemic stroke patients having severe stenosis or occlusion of anterior intracranial…
- Trial name
- RICASO (NCT06823128)
- Testing
- RIC, Guideline-based therapy
- Where
- China
- Volunteers
- 458 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China