Clinical trials: Ischemic Conditioning
Hypercholesteremia, Endothelial Dysfunction
The Effect of Remote Ischemic Conditioning in Patients With Hypercholesterolemia
There is an on-going discussion weather remote ischemic conditioning (RIC) is effective in limiting the damage of reperfusion injury in STEMI patients.
- Trial name
- NCT05164185
- Testing
- Remote ischemic conditioning
- Where
- Sweden
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Subarachnoid Hemorrhage, Cerebrovascular Disorders
Remote Ischemic Conditioning for Efficacy in Patients With Aneurysmal Subarachnoid Hemorrhage
Several recent large-scale clinical trials aimed at improving subarachnoid hemorrhage(SAH) outcomes have concluded with negative results, failing to enhance the prognosis for these patients.
- Conditions
- Subarachnoid Hemorrhage, Cerebrovascular Disorders, Brain Diseases, Stroke
- Trial name
- REPAIR (NCT06711302)
- Testing
- Remote Ischemic Conditioning treatment instrument
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Tiantan Hospital
Moyamoya Disease
Safety and Efficacy of Remote Ischemic Conditioning Combined EDAS on Ischemic Moyamoya Disease
Encephaloduroarteriosynangiosis (EDAS) is widely used as an indirect technique for treatment of moyamoya disease. Nevertheless, this indirect surgery tends to establish insufficient collateral circulation in most adult MMD…
- Trial name
- RIC-IMD (NCT04917003)
- Testing
- RIC plus EDAS, EDAS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Endothelial Dysfunction
To Compare the Ischemic Pre-conditioning and Post-conditioning on Reperfusion Injury in Humans.
Reperfusion Injury occurs by the sudden blood flow to the injured and ischemic myocardium during restoration of blood flow either by Mechanical revascularization or thrombolysis.
- Trial name
- NCT00385151
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emory University
Microcirculation
Changes in Tissue Microcirculation During Ischemic Conditioning: Pilot Study
Changes in tissue microcirculation during ischemic conditioning (4 cycles of 5-min ischemia and 5-min reperfusion) has not been well documented.
- Trial name
- NCT03089814
- Testing
- ischemic conditioning
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
CRIC Combined With MFT for Cardiovascular Adverse Events in Patients With Incomplete Revascularization of CAD
The main objective of this study is to demonstrate whether the combination of chronic remote ischemic conditioning and mindfulness therapy can reduce cardiovascular adverse events in patients with incomplete revascularization of…
- Trial name
- CRCMF (NCT06820970)
- Testing
- chronic remote ischemic conditioning, Mindfulness Therapy
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Coronary Artery Bypass, Myocardial Reperfusion Injur
Remote Ischemic Conditioning to Attenuate Myocardial Death and Improve Operative Outcome.
This study evaluates the addition of remote ischemic preconditioning and postconditioning to standard myocardial protection protocol in patients submitted to off - pump coronary artery bypass grafting in a prospective, 1:1…
- Conditions
- Coronary Artery Bypass, Myocardial Reperfusion Injur, Ischemic Preconditioning, Myocardial, Ischemic Postconditioning
- Trial name
- RICARDO (NCT03363958)
- Testing
- Remote Ischemic Preconditioning with Postconditioning
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Medinet Heart Centre
Aortic Dissection Type A
Remote Ischemic Preconditioning for Aute Type A Aortic Dissection Surgery
The goal of this clinical trial is to learn if a technique called remote ischemic preconditioning (RIPC) helps protect organs during emergency surgery for acute type A aortic dissection (ATAAD).
- Trial name
- NCT07383909
- Testing
- Remote ischemic preconditioning (RIPC)
- Where
- 16 sites in China
- Volunteers
- 1,312 people
- Sponsor
- Fujian Medical University
Liver Failure, Carcinoma, Hepatocellular
Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety Study
This study will assess the feasibility of lower limb-ischemia induced Remote Ischemic Conditioning (RIC) in the perioperative period before, during, and after Orthotopic Liver Transplantation (OLT).
- Trial name
- NCT02635347
- Testing
- Remote Ischemic Conditioning (RIC), Pneumatic tourniquet
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Rutgers, The State University of New Jersey
Intracranial Hemorrhages
Safety and Efficacy of Remote Ischemic Conditioning for Spontaneous Intracerebral Hemorrhage
The purpose of this study is to determine the efficacy and safety of remote ischemic conditioning in treating acute intracerebral hemorrhage.
- Trial name
- NCT05609110
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Yi Yang
Stroke, Stroke, Ischemic
Ischemic Conditioning Improves Walking Function Post Stroke
This innovative study will address scientific and clinical areas relatively unexplored in chronic stroke that could lead to greater recovery of walking.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Cardiovascular
- Trial name
- NCT04038697
- Testing
- Ischemic Conditioning, Treadmill Training
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Hypertension,Essential, Prehypertension
The Antihypertensive Effect of Remote Ischemic Conditioning (RIC-HTN).
This study intends to further reveal the antihypertensive effect of LRIC and explore its potential mechanisms.
- Trial name
- NCT04915313
- Testing
- Remote ischemic conditioning (RIC)
- Where
- 3 sites in China
- Volunteers
- 95 people
- Sponsor
- Capital Medical University
Ischemia Reperfusion Injury
The Effects of Post-Conditioning and Administration of Vitamin C on Intramuscular High Energy Phosphate Levels
Ischemic injury to muscular tissue is common in cardiovascular medicine. The most effective treatment to avoid ischemic damage is the rapid re-establishment of reperfusion.
- Trial name
- IRI in MRI (NCT00534924)
- Testing
- Vit C, Postconditioning, no intervention
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Coronary Artery Disease (CAD)
Hypoxia Pre-conditioning and Mountain Sport
Mountain sport activities as for example hiking or skiing may involve the risk of adverse health events especially in older people not accustomed to the specific mountain sport at altitude or people with pre-existing health…
- Trial name
- Hyx-PRE-Spo (NCT04725539)
- Testing
- hypoxic exposure
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Institute of Mountain Emergency Medicine
Elderly Patients, Acute Ischemic Stroke
Protective Effects of RIC in Elderly With Acute Ischemic Stroke Complicating Acute Coronary Syndrome
Remote ischemic conditioning (RIC) is a noninvasive strategy in which one or more cycles of brief and transient limb ischemia confers protection against prolonged and severe ischemia in distant organs.This study aimed to…
- Conditions
- Elderly Patients, Acute Ischemic Stroke, Acute Coronary Syndrome
- Trial name
- RIC-ACS (NCT03868007)
- Testing
- RIC
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Remote Ischemic Conditioning for the Treatment of Stroke-related Insomnia
This study intends to further reveal the effect of RIC in stroke-related insomnia and explore its potential mechanisms.
- Trial name
- RIC-SI (NCT05289518)
- Testing
- Remote ischemic conditioning (RIC)
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Ji Xunming,MD,PhD
Myocardial Ischemia
Pre-conditioning by Balloon-inflation on Myocardial Injury
Study objectives: To test pre-conditioning by three consecutive 60 seconds balloon inflations, spaced 120 seconds apart, followed by 10 minutes rest prior to PCI reduces the risk of myocardial injury.
- Trial name
- BaMI (NCT05149846)
- Testing
- Pre-conditioning
- Sponsor
- Vastra Gotaland Region
STEMI, CAD
Remote Ischemic Conditioning in STEMI to Decrease Infarct Size
Following acute STEMI patients may have significant myocardial damage and subsequent heart failure. There is currently conflicting data regarding the benefit of remote ischemic conditioning to decrease the magnitude of…
- Trial name
- RemCon-STEMI (NCT03930589)
- Testing
- Remote Ischemic conditioning, Standard of care
- Volunteers
- 251 people
- Sponsor
- University of Alberta
Esophageal Cancer
Laparoscopic Ischemic Conditioning Prior to Esophagectomy
This is a two center phase II prospective single-arm safety and feasibility trial for 20 patients with resectable esophageal carcinoma with an increased risk for anastomotic leakage, as based upon UCS and NASCET calcification…
- Trial name
- ISCON (NCT03896399)
- Testing
- Laparoscopic ischemic conditioning followed by esophagectomy
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 22 people
- Sponsor
- UMC Utrecht
Post-stroke Depression, Remote Ischemic Conditioning
Efficacy of Remote Ischemic Conditioning in Preventing Post-Stroke Depression
Post-stroke depression (PSD) is characterized primarily by low mood and loss of interest following a stroke. It is one of the most common and serious complications of stroke, with an incidence of 11% to 41% within two years…
- Trial name
- NCT06920706
- Testing
- RIC
- Where
- 5 sites in China
- Volunteers
- 240 people
- Sponsor
- Xuanwu Hospital, Beijing