Clinical trials: Ischemic Conditioning
Acute Kidney Injury, Heart Failure
Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major…
- Conditions
- Acute Kidney Injury, Heart Failure, Contrast Induced Nephropathy, Coronary Angiography
- Trial name
- RICH (NCT04982419)
- Testing
- Remote ischemic preconditioning
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Septic Shock
REmote Ischemic COnditioning in Septic Shock
Septic shock remains a major public health problem in industrialized countries, with a mortality rate as high as 50%, largely related to multiple organ dysfunction.
- Trial name
- RECO-Sepsis (NCT03201575)
- Testing
- Remote Ischemic conditioning, Patients with no remote ischemic conditioning
- Where
- 6 sites in France
- Volunteers
- 180 people
- Sponsor
- Hospices Civils de Lyon
Moyamoya Disease, Remote Ischemic Preconditioning
Effects of Remote Ischemic Pre-Conditioning in Moyamoya Disease Patients
In the present study, investigators evaluated whether RIPC reduce the major neurological complications in adult moyamoya disease patients undergoing encephaloduroarteriosynangiosis (EDAS).
- Trial name
- RIME (NCT04064658)
- Testing
- Remote ischemic preconditioning, Encephaloduroarteriosynangiosis
- Where
- 2 sites in China
- Volunteers
- 328 people
- Sponsor
- Beijing Tiantan Hospital
Stroke
Efficacy Study II on Remote Ischemic Conditioning for the Prevention of Stroke-Associated Pneumonia
Verifying whether remote ischemic adaptation can reduce the occurrence of stroke related pneumonia in acute stroke patients within 24 hours of onset
- Trial name
- RICA-2 (NCT05982015)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 1,651 people
- Sponsor
- Capital Medical University
Parkinson's Disease
Remote Ischemic Conditioning for Parkinson's Disease
The purpose is to evaluate feasibility and efficacy of Remote Ischemic Conditioning(RIC) as adjuvant therapy for Parkinson's Disease(PD).
- Trial name
- NCT04327687
- Testing
- Remote ischaemic conditioning, conventional therapy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- General Hospital of Shenyang Military Region
Kidney Transplantation, Delayed Graft Function
Context - Remote Ischemic Conditioning in Renal Transplantation - Effect on Immediate and Extended Kidney Graft Function
The purpose of this study is to determine whether remote ischemic conditioning can improve the outcome after renal transplantation with deceased donor.
- Conditions
- Kidney Transplantation, Delayed Graft Function, Acute Kidney Injury, Glomerular Filtration Rate
- Trial name
- Context (NCT01395719)
- Testing
- Remote ischemic conditioning
- Where
- 4 sites in Denmark, Netherlands and 1 more
- Volunteers
- 220 people
- Sponsor
- University of Aarhus
Unilateral Cerebral Palsy
Effects of Remote Ischemic Conditioning on Bimanual Skill Learning and Corticospinal Excitability in Children With Unilateral Cerebral Palsy
Unilateral cerebral palsy (UCP) is a leading cause of childhood disability. An early brain injury impairs the upper extremity function, bimanual coordination, and impacts the child's independence.
- Trial name
- RIC (NCT05777070)
- Testing
- Bimanual Cup Stacking Training
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- East Carolina University
ST Elevation Myocardial Infarction
Remote Ischemic Conditioning in ST-elevation Myocardial Infarction as Adjuvant to Primary Angioplasty
The primary objective of the RIC-STEMI trial is to assess whether remote ischaemic conditioning (RIC) as an adjunctive therapy during primary percutaneous coronary intervention (PCI) in patients presenting with ST-elevation…
- Trial name
- RIC-STEMI (NCT02313961)
- Testing
- Remote ischaemic conditioning
- Where
- Portugal
- Volunteers
- 516 people
- Sponsor
- Hospital de Braga
Hip Fracture
Remote Ischaemic Conditioning for Post-surgical Complications in Hip Fracture (RIC-FRACTURE)
Background Hip fracture affects 70,000 people in the United Kingdom (UK) and costs an estimated £1.1 billion per year to the National Health Service (NHS).
- Trial name
- RIC-FRACTURE (NCT07178041)
- Testing
- Remote Ischaemic Conditioning
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Contrast-induced Acute Kidney Injury
Biochemical Effects of Remote Ischemic Pre-Conditioning on Contrast-induced Acute Kidney Injury
This a prospective, double-blind, sham-controlled, randomized clinical trial to study the effects of remote ischemic preconditioning on acute kidney injury, vascular and renal biomarkers in patients with non-ST elevation…
- Trial name
- BRICK (NCT03236441)
- Testing
- RIPC
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Oladipupo Olafiranye, MD, MS
Stroke, Acute
Exercise and RIC and TCD
The first week after a stroke is a particularly important time, as improving blood flow may limit secondary ischaemic damage to the brain and help reduce the overall burden neurological injury and future disability.
- Trial name
- NCT03968068
- Testing
- Exercise Procedure, Remote Ischaemic Conditioning
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust