Clinical trials: Ischemic Conditioning
STEMI, Remote Ischaemic Conditioning
Remote Ischaemic Conditioning in STEMI Patients in AFRICA
The RIC-AFRICA trial is a multi-centre, sham-controlled, randomised controlled trial (RCT) involving 1400 ST-segment elevation myocardial infarction (STEMI) patients presenting within ≤ 24 hours of myocardial infarction (MI)…
- Conditions
- STEMI, Remote Ischaemic Conditioning, Myocardial Reperfusion Injury
- Trial name
- RIC-AFRICA (NCT04813159)
- Testing
- Remote Ischaemic Conditioning (RIC)
- Where
- 20 sites in Kenya, Mozambique and 4 more
- Volunteers
- 1,400 people
- Sponsor
- University of Cape Town
Coronary Disease
CRIC Combined With MFT for MFR in Patients With Incomplete Revascularization of CAD
The main objective of this study is to demonstrate whether the combination of chronic remote ischemic conditioning and mindfulness therapy can improve myocardial flow reserve in patients with incomplete revascularization of…
- Trial name
- CRMF-MFR (NCT07514624)
- Testing
- CRIC, MFT
- Volunteers
- 480 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Hematopoietic Stem Cell Transplantations
Remote Ischemic Conditioning in HSCT
This is a feasibility study at a single site, Cincinnati Children's Hospital Medical Center. The hypothesis will be tested using a prospective study design.
- Trial name
- RICH (NCT04808167)
- Testing
- autoRIC®
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Remote Ischemic Conditioning
Effect of RIC on Cerebral Autoregulation in Patients Undergoing Cerebrovascular Stent Implantation
The purpose of this study is to determine the effect of remote ischemic conditioning on cerebral autoregulation in patients undergoing cerebrovascular stent implantation.
- Trial name
- NCT05970653
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Yi Yang
Stroke, Acute, Ischemic Stroke
Rheo-Erythrocrine Dysfunction as a Biomarker for RIC Treatment in Acute Ischemic Stroke
This study aims to investigate whether Remote Ischemic Conditioning (RIC) improves rheo-erythrocrine dysfunction in acute ischemic stroke
- Conditions
- Stroke, Acute, Ischemic Stroke, Cerebrovascular Disorders, Central Nervous System Diseases
- Trial name
- ENOS (NCT04266639)
- Testing
- Remote Ischemic Conditioning
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- Grethe Andersen
Healthy, Young Adults
Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults
The purpose of this research study is to determine if remote limb ischemic conditioning (RLIC) can enhance learning of a motor (balance) and an ecologically valid, complex cognitive-motor (driving) task, and increase skeletal…
- Trial name
- NCT03512028
- Testing
- RLIC, Muscle strength training, Driving training
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Renal Cell Carcinoma
Remote Ischemia Pre-Conditioning in Patients Undergoing Partial Nephrectomy
Partial Nephrectomy has become the standard treatment in patients with tumours <7cm (T1). Even though this is a nephron sparing surgery, there is still potential for acute kidney injury, due to ischemia during the surgery.
- Trial name
- NCT01771003
- Testing
- CellAegis' autoRIC™ Device
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University Health Network, Toronto
Acute Ischemic Stroke, Reperfusion Injury
Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-1b)
Ischemic post-conditioning is a neuroprotective strategy attenuating reperfusion injury in animal stroke models. The investigators have conducted a 3 + 3 dose-escalation trial to demonstrate the safety and tolerability of…
- Trial name
- PROTECT (NCT05909982)
- Testing
- Mechanical thrombectomy combined with ischemic post-conditioning
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University
Intracranial Arteriosclerosis, Ischemic Preconditioning
Remote Ischemic Conditioning Combined With Endovascular Stenting for Symptomatic Intracranial Atherosclerotic Stenosis
The purpose of this registry is to evaluate the safety and efficacy of RIC for patients with symptomatic intracranial atherosclerotic stenosis (sICAS) undergoing endovascular therapy.
- Conditions
- Intracranial Arteriosclerosis, Ischemic Preconditioning, Endovascular Procedures
- Trial name
- NCT05653505
- Testing
- Remote Ischemic Conditioning
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Tianjin Huanhu Hospital
Cerebral Small Vessel Diseases
Remote Ischemic Conditioning on Cerebral Small Vessel Disease
This trial is a randomized, controlled, single-center, double-blind trial. Cerebral small vessel disease (CSVD) patients will be recruited and randomized into RIC or control group.The protective effect of remote ischemic…
- Trial name
- RIC-SVD (NCT04816500)
- Testing
- Automatic ischemic conditioning treatment instrument, Regular treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Old Age, Mobility Limitation
RIC (Remote Ischemic Conditioning) in Older Individuals
The purpose of this study is to examine the feasibility and acceptability of a technique called remote ischemic conditioning (RIC) that aims to improve muscle strength, muscle mass, exercise tolerance, resilience (i.e.
- Conditions
- Old Age, Mobility Limitation, Debility
- Trial name
- NCT06476288
- Testing
- Low-intensity resistance exercise training, High-Dose Remote ischemic conditioning (RIC), Low-Dose Remote ischemic conditioning (RIC)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Duke University
Intracerebral Hemorrhage
Remote Ischemic Conditioning for Intracerebral Hemorrhage
Spontaneous intracerebral hemorrhage (ICH) results from the rupture of small vessels damaged by chronic hypertension, amyloid angiopathy or other disease.
- Trial name
- RICH (NCT03930940)
- Testing
- remote ischemic conditioning, Regular treatment
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Capital Medical University
Embolism Mesenteric
Preoperative Embolization of the Inferior Mesenteric Artery in Colorectal Surgery
Preoperative embolization of the inferior mesenteric artery in colorectal surgery (EPAMIR). This is a prospective, monocentric, non-randomized study.
- Trial name
- EPAMIR (NCT05422560)
- Testing
- Embolization of the inferior mesenteric artery
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Acute Ischemic Stroke
Safety and Efficacy of Remote Ischemic Conditioning Combined With Intravenous Thrombolysis for Acute Ischemic Stroke
The purpose of this study is to determine the efficacy and safety of remote ischemic conditioning combined with intravenous thrombolysis in treating acute ischemic stroke.
- Trial name
- NCT04980625
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 558 people
- Sponsor
- Yi Yang
Retinal Ischemia, Diabetes Complications
Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning in Patients With Type 1 Diabetes
Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury.
- Conditions
- Retinal Ischemia, Diabetes Complications, Ischemia, Diabetes Mellitus, Type 1
- Trial name
- NCT03906383
- Testing
- Remote Ischemic Conditioning
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- University of Aarhus
Ischemic Stroke
Direct Ischemic Conditioning for Endovascular Recanalization for Anterior Large Vessel Occlusion (DICER-aLVO)
Acute ischemic stroke (AIS) is the most common type of stroke, with high incidence rate and mortality. Endovascular therapy is currently the most effective treatment for AIS with large vessel occlusion, but only about 50% of…
- Trial name
- DICER-aLVO (NCT06940128)
- Testing
- Direct Ischemic Conditioning A, Direct Ischemic Conditioning B, Direct Ischemic Conditioning C
- Where
- China
- Volunteers
- 120 people
- Sponsor
- General Hospital of Shenyang Military Region
Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
Effects of Remote Ischemic Conditioning on Hand Use in Individuals With SCI and ALS
Rehabilitation interventions such as physical training and neural stimulation after spinal cord injury (SCI) have been shown to increase neural plasticity.
- Trial name
- NCT03851302
- Testing
- Active Remote Ischemic Conditioning, Isometric hand exercise
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Bronx VA Medical Center
Acute Ischemic Stroke
Effect of Serial Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation in Patients With Intravenous Thrombolysis (SRICDCA-IVT)
The purpose of this study is to determine the effect of serial remote ischemic conditioning on dynamic cerebral autoregulation in patients with intravenous thrombolysis with alteplase.
- Trial name
- SRICDCA-IVT (NCT05550103)
- Testing
- Remote ischemic conditioning, Standard medical treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yi Yang
Critical Illness
Hemodynamic Variations During Remote Ischemic Conditioning in Critical Ill Patients
The main objectives of this study are to evaluate the changes in hemodynamics occurring during the remote ischemic conditioning (RIC) procedure and to compare the hemodynamic responses elicited by passive leg raising before and…
- Trial name
- HERICA (NCT06536231)
- Testing
- Remote ischemic conditioning
- Where
- Lithuania
- Volunteers
- 50 people
- Sponsor
- Lithuanian University of Health Sciences
Esophageal Cancer
Preoperative Arterial Embolization Before Oncologic Esophagectomy as a Technique for Ischemic Gastric Conditioning
This retrospective monocentric comparative study aims to assess the efficacy of preoperative ischemic conditioning, in preventing anastomotic leakage in esophageal cancer surgery.
- Trial name
- NCT06312839
- Testing
- Collecting data from the medical record
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne