Clinical trials: Ischemic Conditioning
Acute Ischemic Stroke
Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy
Ischemic post-conditioning is a neuroprotective strategy that has been proven to attenuate reperfusion injury in animal models of stroke.
- Trial name
- PROTECT (NCT05153655)
- Testing
- Local ischemic post-conditioning
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Capital Medical University
Anterior Myocardial Infarction, Heart Failure
Effect of Intravenous Metoprolol Combining RIC on Myocardial Protection in STEMI Patients
The main purpose of this study is to compare the myocardial protection effect of intravenous metoprolol combined with remote ischemic conditioning (RIC) and single treatment before reperfusion in Chinese patients with anterior…
- Trial name
- NCT03579914
- Testing
- Metoprolol Injectable Product, Romote Ischemic Conditioning (RIC), Metoprolol & RIC
- Where
- 16 sites in China
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Harbin Medical University
Acute Ischemic Stroke
Safety and Effectiveness of Remote Ischemic Conditioning Combined With Intravenous Thrombolysis in Treating Acute Ischemic Stroke
The purpose of this study is to determine the efficacy and safety of remote ischemic conditioning combined with intravenous thrombolysis in treating acute ischemic stroke.
- Trial name
- SERICT-AIS (NCT04027621)
- Testing
- remote ischemic conditioning
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yi Yang
Coronary Artery Bypass Grafting, Remote Ischemic Conditioning
Safety and Efficacy of Remote Ischemic Conditioning for Patients Taking Off-pump Coronary Artery Bypass Grafting
Remote ischemic conditioning (RIC) is the process of repeated ischemia and reperfusion in the peripheral vessels, which is proved in reducing IRI in vital organs.
- Conditions
- Coronary Artery Bypass Grafting, Remote Ischemic Conditioning, Ischemia-Reperfusion Injury
- Trial name
- IMPROVE (NCT06141525)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 648 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Moyamoya Disease
The Safety and Efficacy of RIC on Adult Moyamoya Disease
There are a series of symptoms such as ischemic stroke、transient ischemic attack 、hemorrhagic stroke、headache 、seizure and so on in moyamoya disease( MMD) patients .Nowadays, revascularization is the only effective way for…
- Trial name
- RIC-AMD (NCT04012268)
- Testing
- RIC, Aspirin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Cerebral Infarction
REmote iSchemic Conditioning in acUtE BRAin INfarction Study
Cerebral infarction is the most common form of stroke (80% of strokes). Stroke is the first cause of acquired disability, and the 2nd cause of dementia and death.
- Trial name
- RESCUE-BRAIN (NCT02189928)
- Testing
- Lower limb tourniquet, Usual care
- Where
- 9 sites in France
- Volunteers
- 200 people
- Sponsor
- Versailles Hospital
Stroke, Acute
r-tPA Thrombolytic Therapy in Combination With Remote Ischemic Conditioning for Acute Ischemic Stroke Recovery
to detect the efficiency and safety of intravenous rtPA combined with RIPC in acute ischemic stroke patients
- Trial name
- rtPA-RIC (NCT02886390)
- Testing
- ischemic conditioning
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Safety and Efficacy of Remote Ischemic Conditioning for Acute Ischemic Stroke
The purpose of this study is to determine the efficacy and safety of remote ischemic conditioning for acute ischemic stroke.
- Trial name
- NCT04980651
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 2,210 people
- Sponsor
- Yi Yang
Anthracycline-induced Cardiac Toxicity, Lymphoma
REmote iSchemic condItioning in Lymphoma PatIents REceiving ANthraCyclinEs
Multinational, prospective, proof of concept phase II, double-blinded, sham-controlled, randomized clinical trial (RCT) to evaluate the efficacy and safety of Remote Ischaemic PreConditioning (RIPC) in Lymphoma patients receiving…
- Trial name
- RESILIENCE (NCT05223413)
- Testing
- RIPC
- Where
- 24 sites in Denmark, France and 4 more
- Volunteers
- 608 people
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
High Altitude Polycythemia
The Efficacy of Combination of Traditional Tibetan and Remote Ischemic Conditioning on High Altitude Polycythemia
A multicenter, randomized controlled trial was designed to evaluate the effectiveness and safety of the comprehensive traditional Tibetan medicine program combined with remote ischemic conditioning on high altitude polycythemia.
- Trial name
- NCT06082583
- Testing
- Remote Ischemic Conditioning, Tibetan Medicine (Shiliu Jianwei Powder, Ershiwuwei Yuganzi Pills, Qiwei Tiexue Pill)
- Volunteers
- 300 people
- Sponsor
- Capital Medical University
Myocardial Ischemia
Preconditioning With Sevoflurane and Propofol in Patients Undergoing Minimally Invasive Mitral Valve Surgery
The main aim of this study is to compare markers of cardiac injury (Troponin I), inflammatory response and platelets function during minimally invasive mitral valve repair or replacement (MIMV) via right mini-thoracotomy in two…
- Trial name
- MINI-SEVO (NCT02551328)
- Testing
- sevofluorane
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Fondazione Toscana Gabriele Monasterio
Acute Ischemic Stroke
Safety and Efficacy of Remote Ischemic Conditioning in Patients With Acute Ischemic Stroke
he purpose of this study is to determine the efficacy and safety of remote ischemic conditioning for acute ischemic stroke.
- Trial name
- SERIC-AIS (NCT03669653)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 912 people
- Sponsor
- Yi Yang
Chronic Systolic Heart Failure
Effect of Remote Ischemic Conditioning in Patients With Chronic Ischemic Heart Failure
The present study will evaluate whether treatment with daily remote ischemic conditioning for a 28±4-day period induces beneficial effects in subjects with and without chronic ischemic heart failure in terms of improved left…
- Trial name
- CONDI-HF (NCT02248441)
- Testing
- Daily ischemic conditioning treatment
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- University of Aarhus
Colon Rectal Resection
Ischemic Conditioning (Delay Phenomenon) in Colorectal Surgery
One of the major complications of surgical excision of colorectal cancer includes improper healing of the anastomosis (reconnection of the remaining, cancer free intestine).
- Trial name
- NCT00887497
- Testing
- Angioembolization
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Irvine
Peripheral Arterial Disease, Peripheral Vascular Disease
The Effect of Ischemic Conditioning on Strength and Ambulation in Subjects with PAD
Lower limb amputation is common in the United States, with approximately 150,000 amputations annually. Most individuals walking with a prosthesis demonstrate asymmetrical loading-i.e., they favor the amputated side by placing…
- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Disease, Amputation, Lower Limb Amputation Knee
- Trial name
- NCT04937179
- Testing
- Ischemic Conditioning High - Active Comparator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Illinois Chicago
Remote Ischemic Conditioning
Effect of Remote Ischemic Conditioning on Cerebral Hemodynamics in Patients After Intravenous Thrombolysis (RICCH-IVT)
The purpose of this study is to determine the effect of remote ischemic conditioning on cerebral hemodynamics in patients after intravenous thrombolysis
- Trial name
- NCT05598658
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yi Yang
Out-Of-Hospital Cardiac Arrest
Effect of Remote Ischemic Post-conditioning on Out-of-hospital Cardiac Arrest
Ischemia-reperfusion leads to mitochondrial injury, ion-pump injury, cell membrane damage, cytotoxic edema, and excessive oxygen free radical formation, and eventually destroys cells.
- Trial name
- NCT03093948
- Testing
- Remote ischemic post-conditioning
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Chonnam National University Hospital
Stroke, Acute, Neuroprotection
Effectiveness and Biological Mechanism of Direct Ischemic Post-conditioning for Acute Stroke Patients Due to Large Vessel Occlusion
The goal of this clinical trial is to determine if direct ischemic post-conditioning (IPostC) can alleviate ischemic-reperfusion injury (I/R) in patients who have undergone endovascular thrombectomy (EVT).
- Conditions
- Stroke, Acute, Neuroprotection, Ischemic Conditioning
- Trial name
- NCT06545734
- Testing
- Direct Ischemic Post-conditioning, Endovascular therapy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tianjin Huanhu Hospital
Stroke Acute, Cytoprotection
Ischemic Postconditioning in Acute Stroke Patients Receiving Endovascular Thrombectomy
This clinical trial will evaluate whether on-site ischemic postconditioning (IPostC) improves outcomes in acute stroke patients receiving endovascular thrombectomy (EVT) and explore its mechanisms.
- Conditions
- Stroke Acute, Cytoprotection, Ischemic Conditioning
- Trial name
- NCT06967025
- Testing
- Ischemic Postconditioning, Endovascular Thrombectomy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tianjin Huanhu Hospital
Diabetic Foot Ulcer
Evaluating Remote Ischemic Conditioning (RIC) and Standard of Care vs. Sham Therapy and Standard Care
A double blind, randomized controlled clinical trial comparing wound closure rates of diabetic foot ulcers (DFUs) in subjects receiving active RIC treatment plus standard of care compared to those receiving sham treatment plus…
- Trial name
- NCT04332003
- Testing
- Remote Ischemic Conditioning (RIC) Treatment
- Sponsor
- SerenaGroup, Inc.