Clinical trials: Ischemic Heart Disease
Coronary Artery Stenosis
Kidney Damage in Patients With Normal eGFR
This is a pilot study, randomized, double-blind, parallel group comparison of two iodinated contrast agents used during percutaneous coronary intervention (PCI). All patients enrolled must have normal eGFR.
- Trial name
- NCT01137786
- Testing
- Non ionic contrast media comparator
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Bracco Diagnostics, Inc
Coronary Artery Disease
Safety and Efficacy Study of PB127 Ultrasound Contrast Agent in Patients With Suspected Coronary Artery Disease 007
This trial is to compare PB127 echocardiography to other heart imaging studies.
- Trial name
- NCT00595673
- Testing
- PB127 for injectable suspension
- Where
- 19 sites in United States
- Volunteers
- 428 people
- Sponsor
- Point Biomedical
Cerebral Ischemia, Cardiac Arrest
Neuroprotective Goal Directed Hemodynamic Optimization in Post-cardiac Arrest Patients
The primary objective of the Neuroprotect trial is to assess whether or not a new goal directed hemodynamic optimization strategy can reduce cerebral ischemia in post-cardiac arrest (CA) patients.
- Trial name
- NEUROPROTECT (NCT02541591)
- Testing
- Neuroprotective goal directed hemodynamic optimization, MAP > 65mmHg
- Where
- 2 sites in Belgium
- Volunteers
- 112 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Myocardial Infarction
Two- Dimensional Speckle Tracking Echocardiography After Primary Percutaneous Coronary Intervention
ST-segment elevation myocardial infarction (STEMI) is a major cause of morbidity and mortality worldwide. In spite of decrease in acute and long-term mortality following STEMI in parallel with more use of reperfusion therapy…
- Trial name
- NCT04228510
- Testing
- 2D speckle tracking echocardiography
- Volunteers
- 204 people
- Sponsor
- Assiut University
Myocardial Infarction
Percutaneous Coronary Intervention for Myocardial Infarction at Fujian Provincial Hospital
Research Objectives: This clinical trial aims to evaluate the efficacy and safety of percutaneous coronary intervention (PCI) in patients with myocardial infarction (MI).
- Trial name
- Fu-AMI (NCT07405788)
- Testing
- Percutaneous Coronary Intervention
- Volunteers
- 1,344 people, healthy volunteers welcome
- Sponsor
- Kaiyang Lin
Coronary Artery Disease, HMG-CoA Reductase Inhibitor Toxicity
Pleiotropic Effects of Atorvastatin in High Cardiovascular Risk Patients
The present study constitutes a study examining the effect of atorvastatin on vascular function in high cardiovascular risk patients.
- Conditions
- Coronary Artery Disease, HMG-CoA Reductase Inhibitor Toxicity, Atherosclerosis, Oxidative Stress
- Trial name
- NCT01013103
- Testing
- Atorvastatin, high vs low dose
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- Hippocration General Hospital
Myocardial Infarction
Fractional Flow Reserve (FFR) Stability in Non-Culprit Vessels at ST Elevation Myocardial Infarction(STEMI)
It has been shown that if it can be accomplished within a 90 minute "door to balloon" time, opening an artery in an acute heart attack situation (ST elevation myocardial infarction or STEMI) is best treated with balloon…
- Trial name
- NCT01065103
- Testing
- FFR (Fractional Flow Reserve)
- Where
- 2 sites in Canada
- Volunteers
- 48 people
- Sponsor
- Cardiology Research UBC
Coronary Artery Diseases, Myocardial Infarction
The Efficacy of Influenza Vaccination in Patients With Coronary Artery Diseases
This study wishes to understand: 1. whether vaccination against influenza in coronary artery disease (myocardial infarction and stable angina) patients is as effective as it is in healthy subjects; 2.
- Conditions
- Coronary Artery Diseases, Myocardial Infarction, Stable Angina
- Trial name
- NCT00607217
- Testing
- influenza vaccine
- Where
- Iran
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Myocardial Infarction, Heart Failure, Congestive
Safety and Effects of Implanted (Autologous) Skeletal Myoblasts (MyoCell) Using an Injection Catheter = SEISMIC Trial
To assess the efficacy and safety of MyoCell therapy on myocardial function in congestive heart failure patients, post-myocardial infarction
- Trial name
- NCT00375817
- Testing
- Myoblasts injection with MyoCath catheter
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Bioheart, Inc.
Coronary Artery Disease
Role of Intracoronary Imaging in Plaque Identification
NSTE-ACS patients are more likely to exhibit high-risk plaque characteristics in non-culprit lesions. Both IVUS and OCT imaging techniques interact in a complementary manner to provide morphological characterization of the…
- Trial name
- NCT03953040
- Testing
- intracoronary imaging (IVUS, OCT)
- Sponsor
- Assiut University
Coronary Artery Disease
Validation of Myocardial Perfusion Imaging
The new cadmium-zinc-telluride (CZT) technology is a powerful tool for cardiac nuclear medicine. The increased photon counting sensitivity of camera can be used to explore novel protocols like dual isotope (rapid stress…
- Trial name
- CameraCZT (NCT01785589)
- Testing
- coronary angiography
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Grenoble
Non-ST Elevated Myocardial Infarction
Low Risk Non ST Elevation Myocardial Infarction With or Without Intensive Care Unit Admission
Favourable in-hospital outcome is observed in numerous patients after Non ST myocardial infarction (NSTEMI) with invasive strategy but European guidelines proposed systematic intensive care unit monitoring up to 24 h in lower…
- Trial name
- SELECTNSTEMI (NCT05153889)
- Testing
- Hospitalized in Intensive care unit, Hospitalized in General cardiology ward
- Where
- 3 sites in France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Montpellier
Coronary Artery Disease
Impact of Vascular Reparative Therapy on Vasomotor Function and Myocardial Perfusion:a Randomized H215O PET/CT Study
The purpose of this study is to examine the improvement of myocardial blood flow induced by regained vasomotor functions of the stented coronary segment after resorption of BVS over time.
- Trial name
- VANISH (NCT01876589)
- Testing
- Bioresorbable vascular scaffold, Xience Prime
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Amsterdam UMC, location VUmc
Coronary Artery Disease, Myocardial Infarction
Communicational Program "Trust" to Improve Adherence to Medications
The trial was designed in such a way as to show that the proposed program "Trust" increases the proportion of patients who adhere to therapy in the cohort of those with coronary heart disease for two years after successful…
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Cardiovascular Diseases
- Trial name
- NCT03268291
- Testing
- Standard outpatient observation, Communicational program "Trust"
- Where
- Russia
- Volunteers
- 2,000 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease., Aortic Valve Stenosis.
Cerebral Oxymetry at Elective Coronary and Valve Surgery.
Use of vasopressor to maintain Mean Arterial Pressure on Cardio Pulmonary Bypass can lead to decreased cerebral flow and oxygenation in individual patients and this can be detected by means of cerebral oxymetry.
- Conditions
- Coronary Artery Disease., Aortic Valve Stenosis., Aortic Valve Regurgitation.
- Trial name
- Co-HLM (NCT01940874)
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Oslo University Hospital
Ischemic Heart Disease
Ranolazine for Improving Symptoms of Palpitations
Patients with ischemic heart disease often report multiple symptoms, including angina and palpitations. Ranolazine has antiarrhythmic effects which are largely a result of the drug's effect on multiple ion channels.
- Trial name
- RYPPLE (NCT01495520)
- Testing
- Ranolazine
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Coronary Artery Disease
Diagnostic Performance of On-site Automatic Coronary Computed Tomography Angiography-derived Fractional Flow Reserve
The current study evaluated the diagnostic performance for myocardial ischemia of on-site automatic CCTA-derived FFR (CT-FFR) using a commercially available workstation as compared with invasive FFR as a reference.
- Trial name
- NCT06153927
- Testing
- CT-FFR
- Where
- South Korea
- Volunteers
- 332 people
- Sponsor
- Seoul National University Hospital
Myocardial Ischaemia, Coronary Artery Disease
Evaluation of Effects of Rosuvastatin 40mg on Myocardial Ischemia in Subjects With Coronary Artery Disease
The purpose of this study is to determine whether treatment with 40mg of Rosuvastatin for 8 weeks will reduce the number of episodes of myocardial ischaemia suffered in subjects with coronary artery disease.
- Trial name
- NCT00657527
- Testing
- Rosuvastatin, Cholesterol lowering diet
- Volunteers
- 280 people
- Sponsor
- AstraZeneca
Coronary Artery Disease, Vascularization
Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery
Heart disease is the leading cause of death globally, accounting for 16% of the world's total deaths. The number of cases is expected to increase as our population ages. Heart disease also results in large economic burden.
- Trial name
- ACT for CABG (NCT06207318)
- Testing
- Acceptance and commitment therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Iowa
Valvular Disease, Coronary Stenosis
The Scanner in the Coronary Evaluation
Conventional coronary angiography is the recommended procedure in detection of coronary stenosis in patients with heart valve disease referred for surgery.The aim of this prospective study is to assess diagnostic accuracy of…
- Trial name
- NCT00484380
- Testing
- Coronary scanner
- Where
- France
- Volunteers
- 66 people
- Sponsor
- French Cardiology Society
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