Clinical trials: Ischemic Heart Disease Chronic
Ischemic Heart Disease, Heart Failure
Trial of an Internet-based Platform for Managing Chronic Diseases at a Distance
In 2005, more then one-third of Canadians were burdened with one or more chronic diseases. Patients with one chronic disease often have, or are at risk for, another chronic disease.
- Conditions
- Ischemic Heart Disease, Heart Failure, Chronic Kidney Disease, Diabetes
- Trial name
- iCDM (NCT01342263)
- Testing
- iCDM
- Where
- Canada
- Volunteers
- 234 people
- Sponsor
- Simon Fraser University
Ischemic Heart Disease, Coronary Atherosclerosis
Stress-MRI Assessment After Right Coronary Artery CTO Recanalization
The hypothesis of this study is that Stress-MRI is a clinically significant method of myocardial perfusion assessment after coronary angioplasty with stenting of right coronary artery (RCA) chronic total occlusion (CTO) is…
- Conditions
- Ischemic Heart Disease, Coronary Atherosclerosis, Coronary Artery Disease, Coronary Artery Stenosis
- Trial name
- NCT02769650
- Testing
- CTO coronary angioplasty, Optimal medicamentous treatment, Stress-MRI
- Where
- Russia
- Volunteers
- 72 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease, Coronary Occlusion
Coronary CTO PCI Using Antegrade Wiring Strategy With a First-choice Gladius Guidewire (Gladius First)
The Gladius First trial is designed as a single-centre, open, prospective, randomized clinical trial aimed to assess the efficiency and safety of coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI)…
- Conditions
- Coronary Artery Disease, Coronary Occlusion, Percutaneous Coronary Intervention
- Trial name
- Gladius First (NCT04691778)
- Testing
- CTO PCI with the first-choice Gladius guidewire, CTO PCI without the first-choice Gladius guidewire
- Where
- Poland
- Volunteers
- 69 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Chronic Kidney Disease, Coronary Artery Disease
Cardiovascular Evaluation Before Renal Transplantation
Due to rising importance of cardiovascular disease before and after renal transplantation we have changed our standard diagnostic procedure and perform stress echocardiography and myocardial scintigraphy.
- Trial name
- NCT01064674
- Testing
- diagnostic procedure
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Muenster
Acute Coronary Syndrome, Chronic Coronary Syndrome
A Study on the Peripheral Blood in Patients With Acute Coronary Syndrome
The goal of this study is to conduct analyses the changes of cell growth factors, inflammatory factors, metabolites, plasma proteome, etc.
- Trial name
- NCT06955143
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Coronary Artery Disease
Ticagrelore Alone Post PCI
After PCI for CCS patients, single center double blind randomization will be done and patients will receive aspirin 80 mg and clopidogrel 75 mg versus 90 mg two times daily of ticagrelor, for 6 months and MACE will be followed in…
- Trial name
- TICALONE (NCT06509893)
- Testing
- aspirin 80 mg and clopidogrel 75 mg daily, Ticagrelor 90 MG
- Where
- 2 sites in Iran
- Volunteers
- 5,400 people
- Sponsor
- Shiraz University of Medical Sciences
Coronary Artery Disease (CAD), Peripheral Arterial Disease (PAD)
Rivaroxaban Plus Aspirin in Patients With Chronic Coronary Syndrome and High Ischemic Risk
Registry to describe the impact in terms of effectiveness and safety of the combination treatment of rivaroxaban 2.5 mg twice daily with aspirin on clinical outcomes and practices in a real-life Dutch patient population that are…
- Trial name
- NCT04753372
- Testing
- Rivaroxaban 2.5 MG [Xarelto]
- Where
- 12 sites in Netherlands
- Volunteers
- 645 people
- Sponsor
- Maatschap Cardiologie Zwolle
Refractory Angina, Chronic Stable Angina
Coronary Arteriogenetic Heparinized Exercise
This study evaluates the addition of heparin to a 2-week cycle of physical rehabilitation in the treatment of refractory angina.
- Trial name
- CARHEXA (NCT03350737)
- Testing
- Physical rehabilitation, Heparin
- Where
- Serbia
- Volunteers
- 32 people
- Sponsor
- Clinical Centre of Serbia
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Quebec
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-QC (NCT02789800)
- Testing
- DIMAC02
- Where
- 2 sites in Canada
- Volunteers
- 284 people
- Sponsor
- Université de Sherbrooke
Coronary Occlusion
Single-Arm Study Evaluating Use of the CORA Catheters for the Crossing of Coronary Chronic Total Occlusions
The goal of this clinical trial is to evaluate the safety and effectiveness of the coraFlex, coraForce, and coraCross catheters for crossing chronic total occlusions of the coronary arteries.
- Trial name
- Cora CTO (NCT05848232)
- Testing
- coraFlex Catheter, coraForce Catheter, coraCross Catheter
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- ReFlow Medical, Inc.
Coronary Disease, Coronary Arteriosclerosis
Effects of a Healthy Nordic Diet on Atherosclerosis in Patients with Coronary Heart Disease
Diet can play a key role in atherosclerosis and coronary heart disease (CHD), but little interventional data exists, and the mediators of possible anti-atherosclerotic effects of diet are unclear.
- Conditions
- Coronary Disease, Coronary Arteriosclerosis, Myocardial Infarction, Chronic Coronary Syndrome
- Trial name
- NORDHEART (NCT06701968)
- Testing
- Healthy Nordic Diet, Usual Care
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Uppsala University
Coronary Heart Disease, Chronic Coronary Syndrome
Efficacy and Mechanism of TCCRP in Patients With Chronic Coronary Syndrome Under Fusion Cardiac Rehabilitation Model
This study is a prospective, multi-center, randomized controlled clinical study. It developed an innovative Tai Chi Cardiac Rehabilitation Program (TCCRP) for patients with chronic coronary syndrome (CCS) and evaluated the…
- Trial name
- NCT03936504
- Testing
- Control Group ：conventional exercise rehabilitation programs (CERP), Experimental Group ：Tai Chi cardiac rehabilitation program (TCCRP)
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Chronic Heart Failure, Ischemic Heart Disease
Echo Assessment of Intraventricular Dyssynchrony
Background. Clinical benefits of cardiac resynchronization therapy (CRT) have been clearly demonstrated in heart failure (HF) patients with severe left ventricular (LV) dysfunction and wide QRS at surface electrocardiogram.
- Conditions
- Chronic Heart Failure, Ischemic Heart Disease, Dilated Cardiomyopathy
- Trial name
- IMPROVE (NCT00646243)
- Where
- Italy
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Italian Society of Cardiology
Coronary Artery Disease, Heart Failure With Reduced Ejection Fraction
Validation of Two Wrist-worn Devices for the Assessment of Energy Expenditure in Cardiac Patients.
Improving physical activity is a core component of secondary prevention and cardiac (tele)rehabilitation. Commercially available activity trackers are frequently used to monitor and promote physical activity in cardiac patients.
- Trial name
- NCT03951740
- Testing
- Fitbit Charge 2, Mio Slice, Oxycon Mobile
- Where
- Netherlands
- Volunteers
- 39 people
- Sponsor
- Maxima Medical Center
Ventricular Dysfunction, Myocardial Infarction
Autologous Bone Marrow Transplanted Via Transendocardial Catheter to Chronic Myocardial Infarct Border Zone
The object of this open-labeled, uncontrolled pilot study was to investigate the safety and feasibility of percutaneously transplanting autologous bone marrow (ABM) cells into the myocardium using the helical needle…
- Trial name
- TABMMI (NCT00507468)
- Testing
- Transendocaridal Transplantation of Autologous Bone Marrow
- Where
- 2 sites in Argentina
- Volunteers
- 20 people
- Sponsor
- BioCardia, Inc.
Chronic Coronary Syndrome, Anxiety Disorder
Right Dorsolateral Prefrontal Cortex Closed-loop Neurofeedback for Anxiety in High-ischaemic-risk Chronic Coronary Syndrome
This study is a prospective, randomized, sham-controlled, participant- and assessor-blinded, parallel-group clinical trial designed to evaluate the clinical efficacy, mechanistic effects, and safety of right dorsolateral…
- Conditions
- Chronic Coronary Syndrome, Anxiety Disorder, High Ischemic Risk
- Trial name
- HEART-SET-3 (NCT07543185)
- Testing
- Active right DLPFC closed-loop fNIRS-BCI neurofeedback
- Where
- China
- Volunteers
- 214 people
- Sponsor
- Shenyang Medical College
Myocardial Ischemia
ACT34-CMI -- Adult Autologous CD34+ Stem Cells (Follow-Up Study)
The purpose of this 12-month, observational, follow-up study is to collect additional data (by telephone contact) with which to assess the efficacy, safety, and effects of intramyocardial injections of adult autologous CD34+…
- Trial name
- NCT00545610
- Where
- 23 sites in United States
- Volunteers
- 150 people
- Sponsor
- Lisata Therapeutics, Inc.
Chronic Kidney Diseases, Coronary Artery Disease
Clinical Impact of Orsiro™ Stent in Patient With Chronic Kidney Disease
Orsiro™ or Orsiro_Mission™ stents have the biodegradable polymer and the thinnest stent strut (60㎛) in commercially available stents, which could minimize chronic inflammation and incomplete endothelialization.
- Trial name
- OKAY (NCT06475625)
- Testing
- Percutaneous coronary intervention, Orsiro™ or Orsiro_Mission™ stent
- Where
- South Korea
- Volunteers
- 3,113 people
- Sponsor
- The Catholic University of Korea
Chronic Stable Angina
Management of Ischemic Heart Disease With Angiwell-XR (Ranolazine)
The rationale of MIDA trial is to determine efficacy and tolerability of ranolazine molecule among Pakistan population and obtain firsthand knowledge about the molecule ranolazine.
- Trial name
- MIDA (NCT03486561)
- Testing
- Ranolazine
- Volunteers
- 2,000 people
- Sponsor
- OBS Pakistan
Coronary Heart Disease, Chronic Kidney Disease
Prevalence of Chronic Kidney Disease and Its Association With Clinical Outcome in Patients With Coronary Heart Disease
This is a prospective, multi-center, hospital-based observational study. The aim of the study is to evaluate the prevalence of chronic kidney disease in patients with stable coronar heart disease.
- Trial name
- NCT02509013
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Peking University First Hospital