Clinical trials: Isolation
Military Family, Mental Health Disorder
Blue Star Cares: Innovative Approaches to Helping Military-Connected Caregivers
The purpose of this project is to evaluate an interactive training program for military-connected caregivers (MCCs) of wounded warriors.
- Conditions
- Military Family, Mental Health Disorder, Social Skills, Social Isolation
- Trial name
- BSC (NCT03336190)
- Testing
- avatar-based training
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Atrial Fibrillation
Deliver mOre aPplications for More Durable Pulmonary Vein IsOlation
Pulmonary vein isolation (PVI) by catheter ablation (CA) has become a widely accepted interventional treatment for patients with symptomatic atrial fibrillation (AF) despite anti-arrhythmic drugs (AAD).
- Trial name
- DOPPIO (NCT07021313)
- Testing
- Pulmonary vein isolation by percutaneous endocardial catheter ablation using the FARAPULSE pulsed high voltage electrical field system in patients with atrial fibrillation, Pulmonary vein isolation by percutaneous endocardial catheter ablation using a pentaspline pulsed high voltage electrical field system in patients with atrial fibrillation
- Where
- Netherlands
- Volunteers
- 378 people
- Sponsor
- R&D Cardiologie
Erectile Dysfunction
Evaluation of the Tissue Genesis Icellator Cell Isolation System to Treat Erectile Dysfunction
This clinical study is designed to investigate the safety and potential ability of relocated autologous SVF (stromal vascular fraction) to restore erectile function in men with ED (erectile dysfunction).
- Trial name
- NCT03518333
- Testing
- Injection of adipose derived cells into penis
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Tissue Genesis
Symptomatic Paroxysmal Atrial Fibrillation Without Clinically Significant Heart Diseases
Catheter Cryoablation Versus Antiarrhythmic Drug as First-Line Therapy of Paroxysmal Atrial Fibrillation
The purpose of this study is to evaluate the effectiveness of Pulmonary Vein Isolation (PVI) performed with the Arctic Front™ Advance Cardiac CryoAblation Catheter System as first-line therapy in comparison with antiarrhythmic…
- Trial name
- NCT01803438
- Testing
- cryoballoon ablation system, Antiarrhythmic Drugs
- Where
- 19 sites in Argentina, Australia and 7 more
- Volunteers
- 220 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Paroxysmal Atrial Fibrillation
Durability of Pulmonary Vein Isolation Following Cryoablation for Treatment of Paroxysmal Atrial Fibrillation
The purpose of the study is to determine the permanency of PV isolation with the Arctic Front Advance cryoablation system in paroxysmal AF patients.
- Trial name
- SUPIR (NCT01645917)
- Testing
- Arctic Front Advance Cardiac CryoAblation system
- Where
- Czechia
- Volunteers
- 21 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Isolated Systolic Hypertension
Systolic Hypertension in Europe Placebo-Controlled Trial
The Syst-Eur Trial is a concerted action of the European Community's Medical and Health Research Programme. The trial is carried out in consultation with the World Health Organization, the International Society of Hypertension…
- Trial name
- Syst-Eur (NCT02088450)
- Testing
- Active treatment with nitrendipine (10-40 mg/day).
- Volunteers
- 4,695 people
- Sponsor
- KU Leuven
COVID, Social Isolation
First Level Socio-geriatric Evaluation: ESOGER Databank
Coronavirus disease 2019 (COVID-19) is an infectious disease. Physical distancing is one of the most effective ways to reduce the spread of COVID-19, but this key prevention intervention may have adverse consequences on older…
- Conditions
- COVID, Social Isolation, Anxiety, Frailty
- Trial name
- NCT04393649
- Testing
- ESOGER
- Where
- Canada
- Volunteers
- 20,000 people
- Sponsor
- Jewish General Hospital
Older Adults, Social Isolation
Adaptation and Implementation of an Intensive Geriatric Service Worker (IGSW) Model of Care for Socially Isolated Older Adults
In this study, participants will be randomly assigned to receive either the intervention or control treatment for up to 6 months.
- Trial name
- NCT06603610
- Testing
- Intensive geriatric service worker model of care, Information brochure and telephone follow-up support
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Awareness, Anesthesia, Recall Phenomenon
Awareness in Old Aged Patients During Laryngoscopy and Intubation Using Isolated Forearm Technique
Awareness during general anesthesia - that has an incidence between 0.1% and 0.9% of cases and may be more in elderly - remains a concern for anesthesiologists.
- Conditions
- Awareness, Anesthesia, Recall Phenomenon, Inhalation; Gas
- Trial name
- NCT05019560
- Testing
- Sevoflurane, TIVA
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Core Strength, Power
Effects Of Isolated And Integrated Core Stability Training In Fast Bowlers
The objective of this study will be to compare the effects of isolated and integrated core stability training on power, balance and performance in fast bowlers.
- Conditions
- Core Strength, Power, Balance
- Trial name
- NCT06688227
- Testing
- Isolated Core Stability Program, Integrated Core Stability Program
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Sehat Medical Complex
Multiple Sclerosis, Clinically Isolated Syndrome
Minocycline in MS: Confirmation of Benefit
This is an open-label, single-arm clinical trial. Trial participants will include men and women, aged 18-60 years who have had a first demyelinating event within the previous 180 days and who have brain magnetic resonance imaging…
- Trial name
- MS (NCT04291456)
- Testing
- Minocycline 100mg
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of Calgary
Post Operative Atrial Fibrillation
Prevention of Post-OP AFib Using Combination of CardiaMend and Amiodarone
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing isolated cardiac arterial bypass…
- Trial name
- CAMP POAF (NCT05681182)
- Testing
- CardiaMend with the Addition of Amiodarone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- WakeMed Health and Hospitals
Heart Attack, Cardioplegia Solution Adverse Reaction
Combined Use of a Novel Cardioplegic Formula With MPS® Versus Cardioplexol ® in Urgent Isolated CABG Using MiECC in Patients With Recent Acute Myocardial Infarction
The goal of this study is to compare the two cardioplegia solutions (blood cardioplegia by means of MPS ® vs. Cardioplexol ®) regarding perioperative outcome and with special attention to cardiac markers in patients with a recent…
- Conditions
- Heart Attack, Cardioplegia Solution Adverse Reaction, Coronary Artery Bypass Grafting (CABG)
- Trial name
- NCT04309994
- Testing
- Myocardial protection system (MPS), Cardioplexol
- Where
- Switzerland
- Volunteers
- 307 people
- Sponsor
- University Hospital, Basel, Switzerland
Atrial Fibrillation
Trigger- vs. Substrate-Ablation for Paroxysmal Atrial Fibrillation
The purpose of this study is to compare two strategies of catheter-based treatment of paroxysmal atrial fibrillation: Pulmonary vein isolation either alone or combined with electrogram-guided substrate-ablation.
- Trial name
- NCT00196183
- Testing
- trigger-guided catheter-ablation, trigger+substrate-guided catheter ablation
- Where
- Germany
- Volunteers
- 98 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Social Isolation, Mental Health Wellness 1
Connecting People Implementation Study
This study aims to investigate if the Connecting People (CP) Programme can be implemented by social care practitioners with high fidelity in community mental health teams (CMHTs) and improve the resourcefulness of social networks…
- Conditions
- Social Isolation, Mental Health Wellness 1, Social Interaction
- Trial name
- NCT03945994
- Testing
- Connecting People Intervention
- Where
- United Kingdom
- Volunteers
- 151 people
- Sponsor
- University of York
Atrial Fibrillation
Atrial Ganglionated Plexi Ablation Guided by the SUMO Technology With and Without Conventional Pulmonary Vein Isolation in Patients With Persistent AF
Although circumferential pulmonary vein isolation (PVI) has been considered as the cornerstone for atrial fibrillation ablation, there has been a substantial recurrence rate.
- Trial name
- NCT02492256
- Testing
- Pulmonary vein isolation, GP ablation guided by SUMO technology, ILR implantation
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Myelodysplastic Syndrome
Non-interventional Study of Lenalidomide in the Clinical Routine Treatment of TD Patients With IPSS Low or Int-1 MDS and Isolated Del(5q)
This registry is a prospective, non-interventional, post authorisation safety study for patients diagnosed with Transfusion Dependent, IPSS low or intermediate-1-Risk Myelodysplastic Syndrome (MDS), associated to a single…
- Trial name
- PASS MDS del5q (NCT02279654)
- Testing
- Lenalidomide
- Where
- 148 sites in United States, Belgium and 10 more
- Volunteers
- 389 people
- Sponsor
- Celgene
Atrial Fibrillation (AF)
Atrioventricular Nodal Ablation Versus Pulmonary Vein Isolation - Patient Centred Decisions
The goal of this clinical trial is to compare two procedural approaches to managing atrial fibrillation. The main questions it aims to answer are: Is AF ablation or pacemaker implant and AV nodal ablation a more effective…
- Trial name
- AVENUE PACE (NCT07059208)
- Testing
- Atrioventricular nodal ablation, Pulmonary vein isolation
- Volunteers
- 172 people
- Sponsor
- Sunshine Coast Hospital and Health Service
Pathology, Sigmoid Volvulus
Review of Isolated Hypoganglionosis and Presentation of a New Case Complicated With Sigmoid Volvulus
Isolated hypoganglionosis is rare and constitutes 3-5% of all congenital neurological bowel diseases. Since hypoganglionosis is associated with symptoms such as chronic constipation or pseudo-obstruction, it can be confused with…
- Conditions
- Pathology, Sigmoid Volvulus, Hypoganglionosis
- Trial name
- NCT04363125
- Testing
- Pathology result
- Where
- Turkey (Türkiye)
- Volunteers
- 310 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Atrial Fibrillation
Characterization of Arrhythmia Substrate to Ablate Persistent Atrial Fibrillation
A multicentre, parallel group, two arm, single-blinded randomized clinical trial, assessing the efficacy of a patient-tailored catheter ablation (CA) strategy guided by atrial low voltage area mapping in addition to pulmonary…
- Trial name
- COAST-AF RCT (NCT03347227)
- Testing
- Catheter ablation
- Where
- 14 sites in Canada
- Volunteers
- 510 people
- Sponsor
- Ottawa Heart Institute Research Corporation
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