Clinical trials: Isolation
Multiple Sclerosis
Magnetic Resonance Imaging Study of JM-4 in Multiple Sclerosis/Clinically Patients
This is a Phase 0/1 study of MS patients to determine the safety and potential efficacy of a novel, small human peptide designated as JM-4.
- Trial name
- NCT03887065
- Testing
- JM-4
- Volunteers
- 15 people
- Sponsor
- Cook, Stuart, MD
Education, Isolation
The Effect of Digital Storytelling on Nursing Students' Compliance
This study investigated the effect of digital storytelling on nursing students' compliance with isolation precautions and their knowledge levels.This was a pretest-posttest open-label randomized controlled trial.
- Conditions
- Education, Isolation, Nursing Students
- Trial name
- NCT05022953
- Testing
- Education, dijital storytelling
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people
- Sponsor
- Karadeniz Technical University
Disposable Intestinal Isolation and Protection Device
Disposable Intestinal Isolation and Protection Device for Patients With Rectal and Lower Sigmoid Colon Tumors Undergoing Laparoscopic AR/LAR Surgery
The small intestine is the main organ in the abdominal cavity, approximately 4 to 5 meters in length, occupying most of the middle and lower abdomen.
- Trial name
- NCT07825129
- Testing
- According to the different structures, it is divided into TPYRIB type and TPYRIS type. According to the different outer dimensions of the pocket and the outer sleeve, it is divided into two specificat, sterile gauze
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing Friendship Hospital
Loneliness, Depression
Isolated During COVID-19: Effects of COVID-19's Social Restrictions on Loneliness and Psychosocial Symptomatology
This study seeks to gather data and insight on epidemiologic trends of loneliness and other behaviors in the wake of the CDC recommended "social distancing" during the COVID-19 pandemic.
- Conditions
- Loneliness, Depression, Anxiety, Alcohol Abuse
- Trial name
- NCT04440098
- Where
- United States
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- University of Miami
Stroke, Cardiac Surgery
Effect of Minimally Invasive Extracorporeal Circulation on Optic Nerve Sheath Diameter and Stroke Incidence in Isolated Open Heart Surgery
This prospective randomized controlled trial compares the effects of Minimally Invasive Extracorporeal Circulation (MiECC) versus conventional cardiopulmonary bypass (CPB) on optic nerve sheath diameter (ONSD) and postoperative…
- Conditions
- Stroke, Cardiac Surgery, Cardiopulmonary Bypass
- Trial name
- ONSD-MiECC (NCT07661238)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Multiple Sclerosis, MS, Clinically Isolated Syndrome
Cohort Study of Clinically Isolated Syndrome and Early Multiple Sclerosis
A majority of patients with multiple sclerosis initially presents with a single demyelinating event, e.g. in the optic nerves, brain, brainstem or spinal cord, referred to as a clinically isolated syndrome (CIS).
- Trial name
- CIS-COHORT (NCT01371071)
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
Thrombocytopenia, Hematologic Diseases
Prospective Study of Patients With Thrombocytopenia Following HSCT
Isolated thrombocytopenia is a common and severe complication of HSCT, which often leads to an increased risk of life-threatening hemorrhage, frequent requirement of platelet transfusions and extended hospital stays, representing…
- Trial name
- NCT02487563
- Testing
- Decitabine, rhTPO, Conventional Treatment
- Where
- China
- Volunteers
- 97 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Atrial Fibrillation Chronic, Persistent Atrial Fibrillation
Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (PIVoTAL)
The purpose of this study it to learn whether pulmonary vein isolation (PVI) along with ablation of the posterior left atrial wall (PLAW) will reduce the likelihood of atrial fibrillation (AF) recurrence in patients with…
- Trial name
- PIVoTAL (NCT03057548)
- Testing
- Cryo or Radiofrequency (RF) Ablation only of Pulmonary Veins, Cryo or RF Ablation of Pulmonary Veins plus Ablation of the PLAW
- Where
- 2 sites in United States, Japan
- Volunteers
- 110 people
- Sponsor
- Arash Aryana, MD
Hypertension, Hypertension,Essential
Efficacy and Safety Study of the Fixed-dose Combination of Olmesartan + Indapamide When Compared to the Isolated Drugs in the Treatment of Hypertension.
Phase III clinical trial, multicenter of non-inferiority, randomized, single-blind evaluation of fixed-dose combination of olmesartan + indapamide compared to the isolated drugs in the treatment of hypertension.
- Trial name
- OLINDA (NCT05110898)
- Testing
- fixed-dose of olmesartan 20mg/40 mg + indapamide 1,5 mg, Isolated drugs Olmesartan (20 mg or 40 mg) and Indapamide (1,5 mg)
- Volunteers
- 400 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Lateral Patellar Compression Syndrome, Patellar Dislocation
Tactile Guided Lateral Patellar Release
The lateral edge of the patella is identified by the surgeon's finger and the lateral ligament incision is performed with a blade through the skin.
- Conditions
- Lateral Patellar Compression Syndrome, Patellar Dislocation, Patellar (or Kneecap) Instability and Mal-alignment, Patella Alta
- Trial name
- TGLPR (NCT07637344)
- Testing
- Percutaneous lateral retinacular release of the patella
- Volunteers
- 23 people
- Sponsor
- Issa, Abdulhamid Sayed, M.D.
Postnatal Depression, Social Isolation
Online Singing Interventions for Postnatal Depression in Times of Social Isolation: a Single Arm Study
Melodies for Mums (M4M) is an intervention developed and tested as part of a collaboration between the Royal College of Music, Imperial College London and University College London from 2015-2017.
- Trial name
- SHAPER-PNDO (NCT04857593)
- Testing
- Melodies for Mums
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- King's College London
Multiple Sclerosis
Oral Prednisone Taper Versus Placebo for the Treatment of Acute Relapses in Multiple Sclerosis
The management of MS-patients requires treatment with immune-modifying or immune-suppressive agents to prevent new relapses and progression of disability.
- Trial name
- NCT01411514
- Testing
- Prednisone
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- Claudio Gobbi
Atrial Fibrillation
Effect of the Autonomic Nervous System on the Outcomes of PULSEd Field Ablation to Treat Atrial Fibrillation
Pulmonary vein (PV) isolation is considered the therapeutic strategy of choice to maintain sinus rhythm (SR) in symptomatic patients with atrial fibrillation (AF). The most commonly used energy modality is radiofrequency (RF).
- Trial name
- EASy-PULSE AF (NCT06351553)
- Testing
- Pulmonary vein isolation exclusively with radiofrequency, Pulmonary vein isolation exclusively with pulsed field ablation, Combined pulmonary vein isolation
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Hospital General Universitario de Alicante
Atrial Fibrillation
Ablation Index Guided High Power Ablation for Pulmonary Vein Isolation in Patients With Atrial Fibrillation
The investigators will compare the ablation time during pulmonary vein isolation of Ablation Index-guided high power ablation with those with conventional ablation.
- Trial name
- NCT04379557
- Testing
- Catheter Ablation
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital
Alcohol Abuse, Alcohol Use Disorder
The Effect of Comorbid Alcohol/Substance Use
Study Design This study was designed as a comparative, cross-sectional case-control study examining the effect of comorbid alcohol and substance use disorder (ASUD) on clinical course and social inclusion among individuals with…
- Conditions
- Alcohol Abuse, Alcohol Use Disorder, Substance Use Disorders, Severe Mental Disorder
- Trial name
- NCT07692984
- Testing
- case (comorbid diagnosis), control
- Where
- Turkey (Türkiye)
- Volunteers
- 297 people
- Sponsor
- Abant Izzet Baysal University
Alcohol-Induced Disorders, Ostracism
Role of Adverse Childhood Events and Rejection Sensitivity on Alcohol Use in Recently Withdrawn Individuals With Alcohol Use Disorder
Low utilization of addiction treatment is a public health problem. A number of factors are associated with lack of treatment, including public stigma, self-stigma, and beliefs that people with addiction should solve their problem…
- Trial name
- TRAC (NCT05787106)
- Testing
- Cyberball task
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Melanoma, Uveal Neoplasms
The Scandinavian Randomized Controlled Trial of Isolated Hepatic Perfusion for Uveal Melanoma Liver Metastases
A randomized controlled, open-label, multi-centre study evaluating if Isolated Hepatic Perfusion (IHP) increases Overall Survival compared with Best Alternative Care (BAC) in patients with isolated liver metastases from uveal…
- Trial name
- SCANDIUM (NCT01785316)
- Testing
- IHP
- Where
- Sweden
- Volunteers
- 93 people
- Sponsor
- Vastra Gotaland Region
Cancer, Cancer Metastatic
Evaluating the Effect of a Mobile Audio Companion (Elly) to Reduce Anxiety in Cancer Patients
This is a single-arm, prospective, interventional study in cancer survivors and patients to examine the feasibility of a mobile health application, Elly (Elly Health Inc.), to reduce levels of anxiety, stress, loneliness, and…
- Conditions
- Cancer, Cancer Metastatic, Neoplasms, Breast Cancer
- Trial name
- NCT04604158
- Testing
- Elly Mobile Phone Application
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Gillian Gresham
Video-assisted Thoracoscopic Surgery, Lung Isolation Device
Lung Collapse With Bronchial Blocker
Lung isolation is frequently used during thoracic surgery. Two techniques are principally used: the double lumen tube (DLT) and the bronchial blocker (BB).
- Conditions
- Video-assisted Thoracoscopic Surgery, Lung Isolation Device, One-lung Ventilation, Double Lumen Endotracheal Tube
- Trial name
- NCT01615263
- Testing
- Lung isolation device
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Paroxysmal Atrial Fibrillation
Added Value of Vein of Marshal Ethanol Infusion Compared to Superior Vena Cava Isolation Alone in Patients Undergoing Repeat Ablation for Recurrent Paroxysmal Atrial Fibrillation Despite Durable PV Isolation
The superior vena cava (SVC) is one of the most common non pulmonary vein (PV)-triggers for atrial tachyarrhythmias. SVC electrical isolation can be reached by circular radiofrequency (RF)-ablation under close monitoring of the…
- Trial name
- VEIN-AF (NCT04529785)
- Testing
- SVC only, SVC isolation with substrate modification and vein of Marshal ethanol infusion
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- AZ Sint-Jan AV
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