Clinical trials: Isolation
Atrial Fibrillation, Heart Failure With Reduced Ejection Fraction
Pulsed Field or Cryoballoon Pulmonary Vein Isolation for Atrial Fibrillation in Heart Failure
Patients with atrial fibrillation (AF) and heart failure with reduced left ventricular ejection fraction (HFrEF) are at particularly high cardiovascular risk.
- Trial name
- NCT07181291
- Testing
- PVI
- Where
- 12 sites in Canada, Germany
- Volunteers
- 700 people
- Sponsor
- St. Josefs-Hospital Wiesbaden GmbH
Depression, Anxiety
PHYSICAL ACTIVITY AS A MEASURE OF IMPROVING THE EMOTIONAL STATE AND SOCIALIZATION IN THE ELDERLY
Background: Social isolation, loneliness and anxiety-depressive states are emerging health conditions in the elderly of our society. This situation is related to higher morbidity and mortality.
- Conditions
- Depression, Anxiety, Social Isolation
- Trial name
- NCT04072185
- Testing
- Physical activity
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Mental Health
Effect of a Telephone Reminiscence Intervention on Mental Health
The goal of this study is to learn whether a telephone-based program that helps people share life memories can reduce loneliness and improve mental well-being, life satisfaction, and social support in older adults and their…
- Trial name
- TRIM (NCT07576855)
- Testing
- Telephone Reminiscence Program
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Suture, Complication, Ligament Laceration
Evaluation of Survival and Clinical Outcomes of Patients Treated With Isolated All-inside Meniscal Sutures or With Meniscal Sutures Associated With Ligament Reconstruction
Meniscal tears are among the most common injuries of the knee joint. The average annual incidence is between 60 and 70 cases per 100,000 people.
- Trial name
- Men Repair (NCT07289412)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Stefano Zaffagnini
Itching
Efficacy and Safety of Remo-Wax® Oil (RWO) in Subjects With Isolated Itching of the External Ear Canal
Open, single-arm, non-randomized study to demonstrate the efficacy of Remo-Wax® Oil (abbreviated RWO) in the treatment of isolated itching of the external ear canal and to demonstrate the safety of the product.
- Trial name
- Remo_Itch (NCT05811039)
- Testing
- Remo-Wax® Oil
- Where
- Lithuania
- Volunteers
- 36 people
- Sponsor
- Orion Corporation, Orion Pharma
Atrial Fibrillation
A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation
The purpose of this study is to assess how safe VARIPULSE catheter system is for treatment of a heart rhythm disease called persistent atrial fibrillation (PsAF) in participants who are having a catheter ablation procedure (treat…
- Trial name
- SPAA PFA (NCT07527299)
- Testing
- VARIPULSE Catheter System, LAAO Device
- Where
- 13 sites in United States
- Volunteers
- 1,070 people
- Sponsor
- Biosense Webster, Inc.
Isolated Cervical Dystonia
Cerebellar Transcranial Direct Current Stimulation (tDCS) in Patients With Isolated Cervical Dystonia (CD)
Cervical dystonia (CD) is a movement disorder characterized by involuntary muscle contractions of the neck, leading to abnormal head postures and movement, pain and impaired motor function.
- Trial name
- NCT07014384
- Testing
- Anodal and cathodal ctDCS
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Spina Bifida, Myelomeningocele
Fetoscopic Repair of Isolated Fetal Spina Bifida
The purpose of this investigation is to evaluate maternal and fetal outcomes following fetoscopic repair of fetal spina bifida at the Johns Hopkins Hospital.
- Conditions
- Spina Bifida, Myelomeningocele, Chiari Malformation Type 2, Neural Tube Defects
- Trial name
- NCT03090633
- Testing
- Fetoscopy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Covid19
Covid-19 Patients Management During Home Isolation
The study will investigate management of Covid-19 patients in home isolation.
- Trial name
- NCT04945564
- Testing
- Oxygen therapy and physical therapy, Oxygen therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Atrial Fibrillation
Prophylactic Pulmonary Vein Isolation Study
This study is being done to learn the effects of the Pulmonary Vein Isolation in patients that are at high risk to developing, but do not have a documented history of atrial fibrillation.
- Trial name
- NCT00587899
- Testing
- Pulmonary Vein Isolation
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Mayo Clinic
Alcohol Use Disorder, Alcoholism
Effect of Social Isolation on the Role of Pavlovian Mechanisms for Control Over Alcohol Use
During the first funding period (1st FP) we investigated the impact of acute and chronic stress (Trier Social Stress Test, TSST) on Pavlovian-to-instrumental transfer (PIT).
- Conditions
- Alcohol Use Disorder, Alcoholism, Stress Reaction, Ostracism
- Trial name
- ReCoDe (NCT06256952)
- Testing
- PIT paradigm, social exclusion (Cyberball task), Saliva samples
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Feasibility Study
Stool Sampling in the Acute Isolated Patient , Efficient Acquiring With a Novel Device
stool sample device tested on patients admitted to oncological dept. with diarrhea, in order to shorten time in isolation and time to relevant treatment.
- Trial name
- NCT06495775
- Testing
- quickfact
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Zealand University Hospital
Gingival Recession, Localized
Assessment of Gingival Health Following Rubber-Dam Isolation
The aim of this study is to evaluate the effect of retraction techniques on gingival health. Four different method (212 clamp (Hu-Friedy, USA); Brinker B4 clamp (Coltene Hygenic, USA); dental floss using the simple knot tie…
- Trial name
- NCT05850065
- Testing
- Hu-Friedy 212 clamp, dental floss using the simple knot tie method, Coltene B4 clamp
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Hypertension, Hypertension,Essential
Efficacy and Safety Study of the Fixed-dose Combination of Olmesartan + Indapamide When Compared to the Isolated Drugs in the Treatment of Hypertension.
Phase III clinical trial, multicenter of non-inferiority, randomized, single-blind evaluation of fixed-dose combination of olmesartan + indapamide compared to the isolated drugs in the treatment of hypertension.
- Trial name
- OLINDA (NCT05110898)
- Testing
- fixed-dose of olmesartan 20mg/40 mg + indapamide 1,5 mg, Isolated drugs Olmesartan (20 mg or 40 mg) and Indapamide (1,5 mg)
- Volunteers
- 400 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Pancreatic Cancer, Pancreatic Adenocarcinoma
EUS-guided PORtal Vein Sampling for Circulating Tumor Cells in Pancreatic Cancer Patients
The study aims at evaluating the feasibility and safety of EUS-guided Portal Circulation sampling for isolation, enumeration and profiling od Circulating Tumor Cells (CTC) in Pancreatic Cancer patients.
- Trial name
- EUPhORIC (NCT05247164)
- Testing
- EUS-guided Portal Vein sampling
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- IRCCS San Raffaele
Anxiety, Depression
the Role of Technology in Elderly Patients
Starting from December 2019, the Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-COV-2) disease spread rapidly from China into the world, with about two Mio cases confirmed around the world.
- Conditions
- Anxiety, Depression, Aging, Social Isolation
- Trial name
- SILVER (NCT05000099)
- Testing
- video calls
- Where
- Switzerland
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Paroxysmal Atrial Fibrillation
High Power Short Duration Ablation Compared to Moderate Power Long Duration Ablation for Pulmonary Vein Isolation
High Power Short Duration Ablation Compared to Moderate Power Long Duration Ablation for Pulmonary Vein Isolation: safety and acute procedural outcome
- Trial name
- NCT05959798
- Testing
- High power short duration ablation
- Where
- Germany
- Volunteers
- 204 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Symptomatic Paroxysmal Atrial Fibrillation Without Clinically Significant Heart Diseases
Catheter Cryoablation Versus Antiarrhythmic Drug as First-Line Therapy of Paroxysmal Atrial Fibrillation
The purpose of this study is to evaluate the effectiveness of Pulmonary Vein Isolation (PVI) performed with the Arctic Front™ Advance Cardiac CryoAblation Catheter System as first-line therapy in comparison with antiarrhythmic…
- Trial name
- NCT01803438
- Testing
- cryoballoon ablation system, Antiarrhythmic Drugs
- Where
- 19 sites in Argentina, Australia and 7 more
- Volunteers
- 220 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Neurologic Disorders, Healthy Volunteers
Natural History of Multiple Sclerosis and Its Mimickers
Background: Magnetic resonance imaging (MRI) has been used for decades to help diagnose and monitor neurological disorders like multiple sclerosis (MS). Researchers want to improve how MRI pictures are taken.
- Conditions
- Neurologic Disorders, Healthy Volunteers, Multiple Sclerosis
- Trial name
- NCT02504840
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Discrimination, Racial, Social Isolation
Discrimination and the Brain-Gut-Microbiome (BGM) Axis
Obesity is a major public health problem related to a variety of illnesses such as heart disease and diabetes. Prior research indicates that social stressors contribute to risk for obesity, possibly through alterations in diet…
- Conditions
- Discrimination, Racial, Social Isolation, Stress
- Trial name
- NCT05120908
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
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