Clinical trials: Isolation
Multiple Sclerosis, Clinically Isolated Syndrome
Assessing the Feasibility of the MSPT Device in Routine Clinical Practice in the Swiss Healthcare System
The Multiple Sclerosis Functional Composite (MSFC), a reliable and well-validated instrument, was developed as a multidimensional quantitative measure of neurologic disability in MS.
- Trial name
- MSPT (NCT04599023)
- Testing
- MSPT
- Where
- Switzerland
- Volunteers
- 182 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy, Subjective Cognitive Decline (SCD)
Increasing Physical Activity Through Social Support and Stress Resilience
The goal of this clinical trial is to learn the effects of technology enhancements when combined with basic education, goal-setting, and self-monitoring to increase physical activity among older adults living alone, experiencing…
- Conditions
- Healthy, Subjective Cognitive Decline (SCD), Sedentary Behavior, Social Isolation in Older Adults
- Trial name
- I-PASS (NCT06896825)
- Testing
- Self-monitoring
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Isolated Non Syndromic Left CDH With Postero Lateral Diaphragmatic Defect With Good Perinatal Outcome
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia
In isolated congenital diaphragmatic hernia (CDH), recurrent risk is low suggesting the occurrence of novo mutations (dominant or recessive).
- Trial name
- HCD GENE (NCT02175264)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 73 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rib Fractures
Surgical and Conservative Treatment in Isolated Minor Rib Fractures
The purpose of this research is to compare the outcomes of surgical stabilization and conservative treatment in patients with isolated minor rib fractures.
- Trial name
- NCT04104932
- Testing
- Open reduction and internal fixation
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Pancreatic Neoplasms
Combined Resection vs. Separated Resection After Mobilization of Splenic Vein During Distal Pancreatectomy
Eligible patients will be centrally randomized to either Arm A (resection of the splenic vein after isolation from the pancreatic parenchyma) or Arm B (co-resection of the vein together with the pancreas).
- Trial name
- COSMOS-DP (NCT02871804)
- Testing
- combined resection of the splenic vein, separated resection of the splenic vein
- Where
- Japan
- Volunteers
- 304 people
- Sponsor
- Wakayama Medical University
Urinary Incontinence
PURI-PRO - Symptoms Impact and eHealth Intervention for Menopausal Women With Urinary Incontinence
Urinary Incontinence (UI) is a public health problem that disrupts the Quality of Life, Productivity, Social Isolation and Sexual Function; its prevalence in peri- and postmenopausal women is around 30-40%.
- Trial name
- PURI-PRO (NCT06527638)
- Testing
- Experimental Group: eHealth intervention for UI symptoms improvement, Control Group: Delivery of a Health Literacy single-leaflet
- Where
- Portugal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Heart Failure, Physical Therapy
Isolated Resistance Training and Neuromuscular Electrical Stimulation in Patients With Femoral Intra Aortic Balloon Pump.
The objective of this randomized clinical trial is to compare the effects of a standardized exercise program alone versus the same program combined with neuromuscular electrical stimulation in patients undergoing heart failure .
- Conditions
- Heart Failure, Physical Therapy, Neuromuscular Electrical Stimulation
- Trial name
- NCT06316349
- Testing
- Isolated Resistance Training Program, Neuromuscular electrical stimulation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Atrial Fibrillation, Atrial Flutter
Feasibility Study for Optically Guided Radiofrequency Ablation Catheter
Clinical study intended to evaluate the feasibility of a new irrigated RF ablation catheter that allows the physiologist to perform a regular RF ablation procedure while it is being monitored through an imaging technique known as…
- Trial name
- NEOVIEW (NCT03589742)
- Testing
- AblaView® Ablation Catheter
- Where
- Czechia
- Volunteers
- 4 people
- Sponsor
- Medlumics
Colon Neoplasms
A Novel Technique of HALS With CME and CVL for RCC
The purpose of this study is to determine the short and long outcomes of the novel technique of hand-assisted laparoscopic right hemicolectomy with complete mesocolic excision and central vascular ligation for right colon cancer.
- Trial name
- NCT02625272
- Testing
- Group A
- Where
- China
- Volunteers
- 60 people
- Sponsor
- West China Hospital
Multiple Sclerosis
Sociocognitive Intervention and Rehabilitation Program in Multiple Sclerosis
Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system, involving inflammation, demyelination, and neurodegeneration. It is the most common non-traumatic disabling disease affecting young adults.
- Trial name
- REACT-MS (NCT07734675)
- Testing
- Sociocognitive rehabilitation via COGWEB platform combined with an emotional processing intervention.
- Where
- 2 sites in Portugal
- Volunteers
- 130 people
- Sponsor
- Sonia Batista
Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
SWOG-9239 Reduction of Immunosuppression Plus Interferon Alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant
RATIONALE: Reducing the amount of drugs used to prevent transplant rejection may help a person's body kill tumor cells. Giving biological therapy, such as interferon alfa, which may interfere with the growth of cancer cells, or…
- Trial name
- NCT00002657
- Testing
- bleomycin sulfate, recombinant interferon alfa, cyclophosphamide
- Where
- 86 sites in United States
- Volunteers
- 20 people
- Sponsor
- SWOG Cancer Research Network
Ocular Infection and Inflammation
Non-Inferiority of Gatifloxacin/Prednisolone Association vs Isolated Administration in Prevention of Ocular Infection/Inflammation
The purpose of the study is to evaluate the safety and tolerance of the 0.3% gatifloxacin and 1.0% prednisolone acetate association in eye drops in the prevention of infection and inflammation after refractive surgery (Lasik) and…
- Trial name
- NCT01218737
- Testing
- 0.3% gatifloxacin and 1.0% prednisolone acetate association, isolated 0.3% gatifloxacin and 1.0% prednisolone acetate
- Where
- Brazil
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Atrial Fibrillation
Simplified Pulmonary Vein Isolation Using singLe Catheter and IntraCardiac Echocardiography
Ablation for paroxysmal atrial fibrillation (PAF) by means of pulmonary vein isolation (PVI) is the principal method for the treatment of PAF.
- Trial name
- Simple-ICE (NCT04923009)
- Testing
- ICE visualization and map construction
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Centre of Postgraduate Medical Education
Clinically Isolated Syndrome, Multiple Sclerosis
Predictive Value of the Optic Nerve Involvement in Clinically Isolated Syndrome
Optic neuritis (ON) represents around 30% of clinical presentation of clinically isolated syndrome (CIS). Asymptomatic optic nerve involvement is very frequent in all stage of multiple sclerosis (MS) disease including the CIS.
- Trial name
- HdeFIMS (NCT06455332)
- Testing
- Optic nerve MRI sequence
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Lille
Hashimoto Disease, Adrenal Insufficiency
Isolated ACTH Deficiency in Patients With Hashimoto Thyroiditis
The purpose of this study is to determine whether patients with Hashimoto thyroiditis and impaired well-being may have a partial secondary adrenocortical insufficiency.
- Trial name
- NCT00552487
- Testing
- synacthen
- Where
- Germany
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Lung Separation Techniques, One-Lung Ventilation
Lung Isolation in Thoracic Surgery - a Randomized Trial Comparing the VivaSight™ EB Endobronchial Blocker With Established Devices
Surgery involving the chest cavity, particularly VATS procedures, often require one-lung ventilation. The double-lumen tube (DLT) is considered the gold standard for lung isolation with different models of bronchial blockers (BB)…
- Trial name
- NCT02912598
- Testing
- Mallinckrodt™ Endobronchial Tube, Fuji Uniblocker™, ETView VivaSight™-SL+EB
- Volunteers
- 104 people
- Sponsor
- Otto-von-Guericke University Magdeburg
Systolic Hypertension
An 8-week Study to Evaluate the Dose Response of AHU377 in Combination With Valsartan 320 mg in Patients With Mild-to-moderate Systolic Hypertension
The purpose of the study is to evaluate dose response of blood pressure lowering for 4 doses of AHU377, given once daily (50 mg, 100 mg, 200 mg and 400 mg) in combination with a fixed dose of valsartan (320 mg).
- Trial name
- NCT01281306
- Testing
- LCZ696, Valsartan, AHU377
- Where
- 90 sites in United States, Argentina and 7 more
- Volunteers
- 910 people
- Sponsor
- Novartis Pharmaceuticals
Meniscus Injury
Comparison of Isolated Meniscus Repair Versus Combined Meniscus Repair and Notch Microfracture: A Randomized Controlled Trial Evaluating Functional and Imaging Outcomes
This study aims to evaluate the efficacy of microfracture as an adjunctive augmentation technique in the repair of isolated meniscal tears.
- Trial name
- NCT07609849
- Testing
- Isolated meniscus repair with notch Microfracture, Isolated meniscus repair without notch microfracture
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Multiple Sclerosis
Oral Prednisone Taper Versus Placebo for the Treatment of Acute Relapses in Multiple Sclerosis
The management of MS-patients requires treatment with immune-modifying or immune-suppressive agents to prevent new relapses and progression of disability.
- Trial name
- NCT01411514
- Testing
- Prednisone
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- Claudio Gobbi
Pancreatic Fistula After Pancreaticoduodenectomy
Isolated Roux Loop Pancreaticojejunostomy Versus Pancreaticogastrostomy After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD)is the treatment of choice for patients with periampullary tumour (benign or malignant). In the recent years, the mortality rate of PD has decreased to 5% in many centers.
- Trial name
- PD (NCT01859806)
- Testing
- Pancreaticogastrostomy group, Isolated Roux PJ group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
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