Clinical trials: Isolation
Well Aging, Health Impairment
Effects of Montreal Museum of Fine Arts Visits and Older Community Dwellers With a Precarious State
This study evaluates the effects of MMFA visits on psychological, health, social conditions and personal interactions in older community dwellers with a precarious state and to determine whether these effects may change precarity.
- Conditions
- Well Aging, Health Impairment, Social Isolation, Old Age
- Trial name
- NCT03962985
- Testing
- Guided tour at the Montreal Museum of Fine Arts
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Jewish General Hospital
Psychiatric Disorder
Impact of the Preventive Emotions Management Questionnaire on the Rates of Isolation and Mechanical Restraint Measures in the Psychiatric Admission Unit
This observational study assesses whether the use of the QPGE has an impact on the rates of isolation and mechanical restraint in adult psychiatric admission units.
- Trial name
- PACT (NCT05306717)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 416 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Cancer
Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment
RATIONALE: Caspofungin acetate or amphotericin B liposomal may be effective in preventing or controlling fever and neutropenia caused by chemotherapy, bone marrow transplantation, or peripheral stem cell transplantation.
- Trial name
- NCT00008359
- Testing
- caspofungin acetate, liposomal amphotericin B
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Loneliness, Social Isolation
The Feasibility, Acceptability and Preliminary Efficacy of a Group Intervention to Reduce Loneliness
Severe loneliness is a large and growing clinical and societal problem. Although there are interventions for loneliness, elevated levels often remain.
- Trial name
- NCT05831813
- Testing
- Goal-Based Cognitive Behavioural Intervention
- Where
- Netherlands
- Volunteers
- 9 people
- Sponsor
- University of Amsterdam
Atrial Fibrillation Paroxysmal
Cardioneuroablation for the Treatment of Vagally-mediated Atrial Fibrillation.
Pulmonary vein isolation (PVI) is a cornerstone for catheter ablation of atrial fibrillation (AF), however, exact mechanisms of PVI efficacy remain debatable.
- Trial name
- NCT05461859
- Testing
- Cardioneuroablation (CNA) of the right anterior ganglionated plexus (RAGP)
- Where
- Poland
- Volunteers
- 18 people
- Sponsor
- St. Joseph's Centre, Poland
Arrhythmias, Cardiac, Paroxysmal Atrial Fibrillation
InsightPFA Trial of the LotosPFA Catheter
This trial aims to determine whether the InsightPFA for PVI is as effective and safe as standard RFA in the treatment of symptomatic paroxysmal AF.
- Trial name
- InsightPFA (NCT06014996)
- Testing
- Pulsed Field Ablation (PFA) Therapy, Radiofrequency Ablation（RAF）Therapy
- Where
- 10 sites in China
- Volunteers
- 292 people
- Sponsor
- Insight Medtech Co., Ltd.
Atrial Fibrillation
Reduction in Arrhythmia Burden With Left Atrial Posterior Wall Ablation for Persistent AF
RABLAP-AF will compare pulmonary vein isolation (PVI) in combination with posterior wall isolation (PWI) for patients with persistent atrial fibrillation (AF).
- Trial name
- RABLAP-AF (NCT05195268)
- Testing
- Intracardiac Catheter Ablation
- Where
- United Kingdom
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Trisomy 13, Trisomy 18
High Risk Multiple Gestation Study
The objectives of the clinical study are to demonstrate the accuracy of our proprietary algorithm method to determine the genetic health of the developing fetuses in a multiple gestation pregnancy from a maternal blood sample.
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Sex Chromosome Abnormalities
- Trial name
- NCT02278874
- Where
- 4 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Nutrition Disorders, Malnutrition
Isolated or Combined Use of NUTRIC Score and NRS-2002 to Predict Mortality in the Intensive Care Unit
The objective of this investigation was to assess the predictive capacity of the NUTRIC Score and NRS-2002, separately or combined, in forecasting hospital, 28-day and 3-month mortality in patients with respiratory failure…
- Conditions
- Nutrition Disorders, Malnutrition, Mortality
- Trial name
- NCT06115525
- Testing
- mNUTRIC score, NRS-2002
- Where
- Turkey (Türkiye)
- Volunteers
- 750 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Atrial Fibrillation
Thickness Map-Guided vs. Empirical PV Isolation Using Pulsed Field Ablation for Paroxysmal AF
This is a prospective, multicenter, randomized controlled trial comparing CT-guided versus empirical pulsed field ablation (PFA) for pulmonary vein isolation in patients with paroxysmal atrial fibrillation.
- Trial name
- NCT07068646
- Testing
- CT myocardial thickness map guided PV isolation group, Empirical PV isolation group
- Where
- South Korea
- Volunteers
- 298 people
- Sponsor
- Yonsei University
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q)
Bendamustine and Idarubicin in Treating Older Patients With Previously Untreated AML or MDS
This phase I/II trial is studying the side effects and best dose of bendamustine hydrochloride when given together with idarubicin in treating older patients with previously untreated acute myeloid leukemia (AML) or…
- Conditions
- Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)
- Trial name
- NCT01141725
- Testing
- bendamustine hydrochloride, idarubicin
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Fred Hutchinson Cancer Center
Paroxysmal Atrial Fibrillation
Safety and Feasibility of Electrical Isolation of the Superior Vena Cava for Paroxysmal Atrial Fibrillation
The present study is designed as a observational prospective, multicentre, international. The main aim of this study is to evaluate the safety and feasibility of SVC isolation with the CB in a prospective manner.
- Trial name
- SAFE-SVC (NCT03190096)
- Testing
- SVC isolation
- Where
- 4 sites in Belgium, Italy and 2 more
- Volunteers
- 120 people
- Sponsor
- Ettore Sansavini Health Science Foundation
Patients With Intransit Stage III/IV Melanoma
Phase 1 Dose-finding Study of L19TNFα Plus Melphalan Using Isolated Inferior Limb Perfusion (ILP) in Subjects With Intransit Stage III/IV Melanoma
In this study the recombinant human fusion protein L19TNFα will be associated in ILP with the standard treatment with melphalan 10mg/l limb volume in subjects affected by stage III/IV limb melanoma.
- Trial name
- NCT01213732
- Testing
- Isolated inferior limb perfusion
- Where
- 2 sites in Italy
- Volunteers
- 19 people
- Sponsor
- Philogen S.p.A.
Colorectal Liver Metastases
Safety Study of Oxaliplatin and 5-fluorouracil Followed by FUDR for Unresectable Colorectal Liver Metastases
The purpose of this study is to determine the maximum tolerated dose and dose limiting toxicity of 5-FU in combination with Oxaliplatin delivered via isolated hepatic perfusion.
- Trial name
- NCT00557557
- Testing
- Drug: 5-FU, Drug: Oxaliplatin
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- David Bartlett
Isolated Right Aortic Arch
Management of Prenatally Diagnosed Isolated Right Aortic Arch
The existence of a right aortic arch integrates nosologically into the group of aortic vascular arch anomalies. In the majority of cases, a right aortic arch is associated with cono-truncal congenital heart diseases (CHD), such…
- Trial name
- ARCADE (NCT04029064)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Oximetry, Covid19
Feasibility and Impact of Remote Oximetry in Patients Hospitalized With Covid-19
The objective of MoxiCov is to monitor the oximetry of patients admitted to the Covid nursery to provide a more detailed assistance expecting to reduce the amount of hypoxia in these patients.
- Trial name
- MoxiCov (NCT04587921)
- Testing
- Digital oximeter monitoring
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Catheter-based Ablation of Atrial Fibrillation
Swiss Atrial Fibrillation Pulmonary Vein Isolation Registry
Registry of patients with atrial fibrillation undergoing catheter-based ablation of atrial fibrillation (pulmonary vein isolation) to determine long-term success rates of catheter-based ablation of atrial fibrillation (pulmonary…
- Trial name
- SWISS-AF-PVI) (NCT03718364)
- Testing
- catheter-based ablation of atrial fibrillation (pulmonary vein isolation)
- Where
- 2 sites in Switzerland
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Homeless Persons
Effect of a Rent Subsidy and Mentoring on Youth Transitioning Out of Homelessness
Compared to the vast amount of literature about the risk factors associated with young people entering and becoming entrenched in homelessness, much less is known about how to facilitate and sustain transitions off the streets.
- Trial name
- NCT03779204
- Testing
- Mentorship, Rent Subsidies
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Alcohol Use Disorder, Alcoholism
Effect of Social Isolation on the Role of Pavlovian Mechanisms for Control Over Alcohol Use
During the first funding period (1st FP) we investigated the impact of acute and chronic stress (Trier Social Stress Test, TSST) on Pavlovian-to-instrumental transfer (PIT).
- Conditions
- Alcohol Use Disorder, Alcoholism, Stress Reaction, Ostracism
- Trial name
- ReCoDe (NCT06256952)
- Testing
- PIT paradigm, social exclusion (Cyberball task), Saliva samples
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Atrial Fibrillation Paroxysmal
Esophageal Temperature During PVI Using Q-DOT Micro
This study will assess how two different ablation strategies, using two different ablation catheters during catheter ablation for paroxysmal atrial fibrillation, affect the temperature of the esophagus during ablation, and the…
- Trial name
- NCT06392932
- Testing
- QDOT Micro ablation catheter, ST SF ablation catheter
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
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