Clinical trials: Isthmocele
Isthmocele
Impact of Vertical vs. Transverse Closure on Outcomes of Laparoscopic Correction of Isthmocele
Laparoscopic repair of Isthmocele aims to restore the anatomical integrity and physiological function of the lower uterine segment.
- Trial name
- NCT07625852
- Testing
- Vertical Closure, Transverse Closure
- Volunteers
- 72 people
- Sponsor
- Minia University
Appropriate Diagnostic Criteria of Uterine Niche With Detection of Prevalence , Risk Factors and Associated Symptomes
Prevalence and Risk Factors of Uterine Niche Following Different Caesarean Section Techniques:a Hospital Based Study
The primary objective of this study is to institute clically relevant and objective sonographic criteria for the diagnosis of ceasearan section scar defect(CSSD) once the appropriate diagnostic criteria are established the…
- Trial name
- NCT04933032
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cesarean Section; Dehiscence
The Impact of Cesarean Scar Defects on the Success of Assisted Human Reproduction
The prevalence of Caesarean sections continues to increase around the world. In France, the proportion of Caesarean sections has doubled from 11% in 1981 to 20,2% in 2016, bringing with it an increase in the risk of obstetrical…
- Trial name
- NICHE-ART (NCT04869007)
- Testing
- hysterosonography
- Where
- 5 sites in France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Angers
Gynecologic Disease
Vaginal Repair of Post Cesarean Istmocele
20 WOMEN WITH SYMPTOMATIC POSTCESAREAN ISTHMOCELE (NICHE) WILL BE RECRUITED EVALUATED AND SUBJECTED TO A VAGINAL REPAIR OF THE DEFECT, RESULTS WILL BE ANALYZED.
- Trial name
- OWarda (NCT05125692)
- Testing
- vaginal surgical repair of isthmocele
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Assessment of Uterine Healing
Preliminary Study of Uterine Healing After Caesarean Section: CLInico-ECHOgraphic and Anatomopathologic COrrelation
Caesarean section is one of the most common surgical procedures. The multiplication of uterine scars leads to an increase in complications and in particular those related to poor healing such as isthmocele or uterine rupture.
- Trial name
- COCLIECHO (NCT05785559)
- Testing
- uterine biopsies
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abnormal Uterine Bleeding
Effectiveness of Three Steps Hysteroscopic Repair of Post Caesarean Isthmocele in Patients With Post Menstrual Spotting
Isthmocele is one complications of repeat cesarean sections which is considered as a pocket .that accumulate menstrual blood causing post- menstrual spotting Hysteroscopic resection of the edges of the isthmocele is considered…
- Trial name
- NCT05062551
- Testing
- three steps hysteroscopic resection of an isthmocele
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mervit Sersy
Isthmocele
Isthmocele - Prediction, Prevention, Diagnosis, and Management
An Isthmocele is a scar defect or uterine niche that develops in the myometrium due to an inadequate healing process at the site of the caesarean section incision.
- Trial name
- NCT04566575
- Testing
- trans vaginal ultrasound (TVUS), patient questionnaire
- Where
- Switzerland
- Volunteers
- 27 people
- Sponsor
- University Hospital, Basel, Switzerland
Infertility, Implantation
Impact of a Previous CS on the Ongoing Pregnancy Rate in Single Euploid Frozen Embryo Transfer (ET)
As embryo ploidy is a crucial factor not only for implantation but also for maintenance of a pregnancy, the aim of this study is to evaluate the impact of the CS / isthmocele on the ongoing pregnancy rates and the implantation…
- Trial name
- NCT05798624
- Testing
- Ultrasound between 6+0 and 6+7 weeks of pregnancy - With Isthmocele, Ultrasound between 6+0 and 6+7 weeks of pregnancy - Without Isthmocele, Ultrasound between 6+0 and 6+7 weeks of pregnancy
- Where
- United Arab Emirates
- Volunteers
- 1,050 people
- Sponsor
- ART Fertility Clinics LLC
Isthmocele, Cesarean Scar Defect
Clinical Impact of Uterine Repair During Cesarean Section with Barbed Suture on the Incidence of Isthmocele
Pregnant women, irrespective of their pregnancy risk, who undergo a cesarean section for any reason will be randomized to one of two suturing techniques: conventional suture or barbed suture for uterine repair after the cesarean…
- Conditions
- Isthmocele, Cesarean Scar Defect, Pelvic Pain, Spotting
- Trial name
- CESARIS (NCT06691750)
- Testing
- Barbed suture, Conventional smooth suture
- Where
- Spain
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Uterine Scar, Cesarean Section Complications
Single or Double-layer Uterine Closure Techniques
There are different surgical techniques of uterine closure during cesarean. A growing data has suggested that the closure technique has an effect on uterine scar healing.
- Conditions
- Uterine Scar, Cesarean Section Complications, Cesarean Section; Dehiscence
- Trial name
- NCT03629028
- Testing
- Residual myometrium thickness, Niche Presence, Adjacent myometrium thickness
- Where
- Turkey (Türkiye)
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Safak Baran Yilmaz
Endometrial Diseases
Intrauterine Microbiota During IVF in Patients Affected With Isthmocele.
To evaluate the endometrial and isthmic microbiota in patients with isthmocele after C-Section, and if this microbiota is similar or not with better reproductive outcomes.
- Trial name
- NCT03519763
- Testing
- ultrasound
- Where
- United Arab Emirates
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Isthmocele
Can Cesarean Scar Defects be Prevented?
In this study, uterotomy after cesarean section was performed using 3 different suture techniques and aimed to demonstrate the potential of the baseball suture technique to prevent the isthmusel complication known as cesarean…
- Trial name
- NCT06761495
- Testing
- Baseball Suturing Technique, Single-Layer Locked Continuous Suturing Technique, Single-Layer Unlocked Continuous Suturing Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istinye University
Cesarean Scar Defect
Isthmocele After Two Different Sutures in Cesarean Section
Cesarean delivery (CD) rates are rising globally. about 30% of women delivered by CD in 2015 only in the USA. This increasing CD rate has stimulated an interest in the potential short- and long-term morbidity of CD scars.
- Trial name
- NCT04073264
- Testing
- monofilament
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Federico II University
Cesarean Section Complications, Uterine Scar Diverticulum
Preventing Isthmocele After Cesarean Section
Cesarean section accounts for nearly 30% of births in Canada, and is the most commonly performed surgery by Obstetrician Gynecologists.
- Conditions
- Cesarean Section Complications, Uterine Scar Diverticulum, Uterine Scar From Previous Cesarean Delivery
- Trial name
- (PICS) (NCT03826459)
- Testing
- Non-Locking Uterine Closure, Locked Uterine Closure
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada