Clinical trials: Ivf
Antichlamydial Antibodies, Chlamydia Trachomatis Infection
Cohort Study Investigating the Association Between Antichlamydial Antibody Positivity and ART Outcomes in Women With TFI
In a prospective cohort study investigators will examine characteristics and clinical outcomes of treatment with ART in women with tubal factor infertility (TFI) with regard to seropositivity to antichlamydial antibodies.
- Conditions
- Antichlamydial Antibodies, Chlamydia Trachomatis Infection, Infertility, Tubal Factor Infertility
- Trial name
- NCT04139629
- Testing
- antichlamydial antibody test, treatment of infertility with ART
- Where
- Russia
- Volunteers
- 292 people
- Sponsor
- D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology
Infertility
Study of Optimal Posology of Gonadotrophins in Patients With Insufficient Ovarian Response Due to Age
In In vitro fertilization (IVF) treatment, poor responder patients of more than 38 years old are randomized prospectively into two dosages of gonadotrophins. The outcome of treatment will be analyzed.
- Trial name
- NCT00575302
- Testing
- Gonal-f®: follitropin alpha
- Where
- 4 sites in Belgium
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Chretien
Luteal Phase
Vaginal Versus Combined Use of Progesterone in Fresh IVF/ICSI Cycles
Hypothesis: the combined use of progesterone administration for luteal phase support is superior to the single route of progesterone administration in terms of pregnancy outcome parameters in women undergoing fresh IVF/ICSI…
- Trial name
- NCT05089383
- Testing
- Utrogestan
- Where
- Greece
- Volunteers
- 698 people, healthy volunteers welcome
- Sponsor
- University of Athens
IVF
Effect of Tadalafil, Sildenafil and Pentoxyfylline on Frozen Embryo Transfer Outcomes
The aim of this study is to investigate the Effect of different vasodilators as Tadalafil, Sildenafil and pentoxyfylline in In vitro Fertilization.
- Trial name
- NCT05971667
- Testing
- tadalafil, Sildenafil, pentoxifylline
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Infertility/Sterility
Cetrorelix and Ganirelix Flexible Protocol for (IVF)
Recombinant gonadotropins are currently used for ovarian stimulation in women undergoing to IVF for infertility. Recently new flexible protocols have been introduced: the "single dose" and "multiple dose" protocol.
- Trial name
- IVF (NCT03477929)
- Testing
- Ganirelix Acetate, Cetrorelix Acetate
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Infertility, Male
G-IVF and Sperm Parameters
The aim of this study is to investigate if adding a fixed volume of a physiological solution to a freshly produced sperm sample will affect sperm characteristics.
- Trial name
- NCT05597631
- Testing
- G-IVF PLUS
- Where
- Greece
- Volunteers
- 118 people
- Sponsor
- Vitrolife
Infertility
To Investigate Efficacy and Safety of a Single Injection of Org 36286 for Ovarian Stimulation Using Daily Recombinant FSH as Reference (Ensure)(P05690/MK-8962-001)
Clinical trial objectives are to investigate the efficacy and safety of a single injection of 100 μg Org 36286 in women weighing 60 kg or less to induce multifollicular development for controlled ovarian stimulation (COS), using…
- Trial name
- Ensure (NCT00702845)
- Testing
- corifollitropin alfa (Org 36286), recFSH (follitropin beta), gonadatropin releasing hormone (GnRH) antagonist (ganirelix)
- Volunteers
- 397 people
- Sponsor
- Organon and Co
Infertility, Female
Clinical Measures of Ovarian Reserve in Predicting IVF Success
The purpose of this study is to find out more about tests used to estimate the number of eggs a woman has remaining in her ovaries (her 'ovarian reserve').
- Trial name
- NCT01756872
- Testing
- Measurements of ovarian reserve
- Where
- United Kingdom
- Volunteers
- 204 people
- Sponsor
- University of Oxford
Infertility, Male Infertility
To Investigate if the Harvester® Improves Sperm Motility and Blastocyst Utilization (the Percent of Fertilized Eggs That Develop to the Point That They Are Able to be Transferred) in IVF Cycles.
The goal of this prospective, multicenter randomized controlled clinical trial is to evaluate whether the SwimCount Harvester microfluidic sperm preparation device can achieve equivalent or superior clinical outcomes compared to…
- Conditions
- Infertility, Male Infertility, InVitro Fertilization, Aneuploidy Rate
- Trial name
- NCT07369362
- Testing
- microfludics semen processing device
- Where
- United States
- Volunteers
- 1,600 people
- Sponsor
- MotilityCount aps
Normal Endometrial Physiology
Endometrial Basis for Infertility in Women With Recurrent Implantation Failure and Pregnancy Loss
Background: Pregnancy loss is the most common complication of pregnancy. It occurs in roughly one-half of natural conceptions. It most frequently occurs in the first 2 to 3 weeks of pregnancy.
- Trial name
- NCT04939064
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infertility, Endometritis
Chronic Endometritis in Patients With Recurrent Miscarriages or Repeated Implantation Failures in In-vitro Fertilization
Chronic endometritis is a persistent inflammation of the endometrium. Chronic endometritis is asymptomatic or little symptomatic.
- Conditions
- Infertility, Endometritis, Abortion, Spontaneous
- Trial name
- NCT01762098
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Clinique Ovo
Infertility
Efficacy Study of Granulocyte-macrophage Colony Stimulating Factor (GM-CSF) for Use in Human IVF
This study is to assess whether addition of 2 ng/ml GM-CSF into a specific culture medium will increase the chance of a pregnancy after in vitro fertilisation.
- Trial name
- GM-CSF (NCT00565747)
- Testing
- Test culture, Control culture
- Where
- 14 sites in Denmark, Sweden
- Volunteers
- 1,332 people
- Sponsor
- Origio A/S
IVF
Propofol Sedation vs. Anaesthetist Guided Anaesthesia in Oocyte Pickup
Patients undergoing their first course of in vitro fertilisation receive either gynaecologist guided propofol only sedation or anaesthetist guided full anaesthesia.
- Trial name
- NCT05741814
- Testing
- Propofol
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Wunschbaby Institut Feichtinger
Infertility, Subfertility
Effect of hCG on Receptivity of the Human Endometrium
Worldwide, 1 in 12 couples experience difficulty in getting pregnant and seek the help of assisted reproductive technologies (ART) such as in vitro fertilization (IVF-egg is fertilized by sperm outside the body), ovarian…
- Trial name
- NCT01786252
- Testing
- human chorionic gonadotropin (hCG)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Infertility, Preimplantation Genetic Screening
Investigating the Cryopreserved Blastocyst's ImplantatiOn Potential After Genetic Screening
This is a two-arm parallel group randomized controlled trial at the Department of Reproductive Medicine at Ghent University Hospital.
- Trial name
- BIOPS (NCT03173885)
- Testing
- Preimplantation Genetic Screening
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University Hospital, Ghent
Infertility
Efficacy and Safety Study of a Single Injection of SCH 900962 Versus Daily recFSH Injections in Women Undergoing Controlled Ovarian Stimulation (Study P06029)
The purpose of this study is to show that a single injection of SCH 900962/MK-8962 is non-inferior to daily injections of recombinant follicle-stimulating hormone (recFSH) during the first week of ovarian stimulation in terms of…
- Trial name
- PURSUE (NCT01144416)
- Testing
- SCH 900962 / Corifollitropin alfa / Org 36286, RecFSH / follitropin beta
- Volunteers
- 1,424 people
- Sponsor
- Organon and Co
Assisted Reproductive Technology, Freezing/Thawing Procedure
Study of the Impact of Freezing-thawing Procedures and the Prolonged Culture of Embryos on Epigenetic Regulation in Humans
For this project, 4 groups of 38 infants have been created so as to evaluate the impact of Assisted-Reproduction Technology (ART) and more particularly the two procedures classically used in ART: the freezing/thawing of embryos…
- Conditions
- Assisted Reproductive Technology, Freezing/Thawing Procedure, Prolonged Culture Procedure
- Trial name
- NCT02171884
- Testing
- Sample of cord blood, Sample of placenta
- Where
- 2 sites in France
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Infertility, Pregnancy Rate, Live Birth
Live Births With Low Oxygen Blastocyst Culture
The potentially damaging effect of free O2 radicals to cultured embryos may be reduced by adding scavengers to the culture media or by reducing the incubator O2 levels.
- Conditions
- Infertility, Pregnancy Rate, Live Birth, In Vitro Fertilization
- Trial name
- Oxygen (NCT00708487)
- Testing
- Embryo incubator oxygen concentration
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Texas Health Resources
Infertility
Eeva™ Continued Access Study: Assessing the Usability of Eeva in a Clinical Setting
User questionnaire of Eeva System usability and reports of device malfunctions.
- Trial name
- CAS (NCT01617993)
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- Progyny, Inc.
Preterm Labor
Group B Streptococcus (GBS) Infection and in Preterm Labor Women Conceived Through IVF
This is a cross - sectional study to determine the prevalence of GBS infection and associated factors in preterm labor women conceived through ART. 221 subjects will be involved.
- Trial name
- NCT03122704
- Testing
- GBS screening
- Where
- Vietnam
- Sponsor
- Manh Tuong Ho
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