Clinical trials: Ivf
Medically Assisted Procreation (MAP), Oocyte Retrieval
Monocentric Randomised Controlled Trial to Assess Whether Virtual Reality Reduces the Use of Hypnotic Agents During IVF/ICSI Oocyte Retrieval
Over the last few years, audiovisual distraction devices using animation, films and 3D immersion have been developed, with the aim to provide patients with a relaxing experience that disconnects them from the operating…
- Trial name
- REVAHPOVO (NCT07190729)
- Testing
- Propofol sedation + Audiovisual distraction, Propofol sedation
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Infertility, In Vitro Maturation of Oocytes
Aspire In Vitro Maturation Study
A study to assess the Capacitation - in-vitro maturation (CAPA-IVM) system as an option for patients with a good ovarian reserve to achieve pregnancy.
- Conditions
- Infertility, In Vitro Maturation of Oocytes, Assisted Reproduction Technologies
- Trial name
- AIM (NCT07789730)
- Testing
- CAPA-IVM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Inception Fertility Research Institute, LLC
IVF
Decision Support Tool for Gonadotrophin Dose Selection in ART.
A multi-center randomized clinical trial is proposed to study the effectiveness of the advanced decision support tool Opt-IVF in reducing medication, testing, and improving outcomes.
- Trial name
- OptIVF3 (NCT05811065)
- Testing
- OPTIVF dosage, traditional drug treament
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Stochastic Research Technologies LLC
Infertility, Endometriosis
Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp
A Phase 3 clinical trial of oral GnRH antagonist pre-treatment for women with endometriosis who are undergoing IVF, with a primary outcome of live birth rate.
- Trial name
- PREGnant (NCT06375811)
- Testing
- Elagolix 200 MG
- Where
- 5 sites in United States
- Volunteers
- 97 people
- Sponsor
- Yale University
Ovarian Stimulation
Dehydroepiandrosterone Supplementation for Poor Responder Patients During in Vitro Fertilization Treatment
The aim of this study was to evaluate the effect of dehydroepiandrosterone supplementation on in vitro fertilization performance and outcome among poor-responder patient.
- Trial name
- NCT01145144
- Testing
- dehydroepiandrosterone crystalline fine powder
- Where
- 2 sites in Israel
- Sponsor
- Meir Medical Center
Assisted Reproductive Techniques
Double Stimulation in Women With Low Prognosis in ART
The main objective of this study is to compare the cumulative ongoing pregnancy rates of two different IVF protocols in women candidate for ART characterized by low prognosis.
- Trial name
- NCT04531644
- Testing
- double stimulation, conventional ovarian stimulation
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tu Du Hospital
Infertility, Miscarriage
Ism1 Versus EmbryoGen Media for Embryo Culture in Previous Pregnancy Loss Cases
Recently, it has been suggested that culture of embryos in EmbryoGen medium can increase the live birth rate in IVF patients with a previous history of pregnancy loss.
- Trial name
- NCT01689428
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Biogenesi
Dietary Supplements
Effectiveness of Adjuvant Supplements Prior to in IVF
To investigate the effect of combined DHEA, CoQ10 and tocotrienol on IVF cycles in poor ovarian responders
- Trial name
- NCT05471453
- Testing
- DHEA, DHEA+CoQ10+Tocotrienol
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Infertility Assisted Reproductive Technology
Prospective International Multi-center Clinical Trial of PGT-A Upgrade
The goals of this international multicenter cross-sectional study are: 1. To provide patients with a comprehensive PGT solution capable of simultaneously detecting embryonic chromosomal aneuploidy, mosaicism, microdeletions/…
- Trial name
- NCT07533630
- Testing
- PGT-A upgrade
- Where
- 7 sites in Argentina, China and 3 more
- Volunteers
- 1,700 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Infertility,Female
G-CSF and PRP in Patients With Recurrent Implantation Failure
The aim of this randomized controlled trial is to determine whether granulocyte colony-stimulating factor and platelet-rich plasma can be used to enhance the IVF-ET outcomes in patients with recurrent implantation failure
- Trial name
- NCT04411212
- Testing
- Granulocyte colony-stimulating factor and platelet-rich plasma group, Control group
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Riyadh Fertility and Reproductive Health center
Primary Ovarian Insufficiency, Female Infertility Due to Diminished Ovarian Reserve
Effect of Testosterone Treatment on Embryo Quality
The purpose of this study is to determine the effect of treatment with trans-dermal testosterone cream compared to placebo on measures of ovarian reserve, oocyte and embryo quality, and pregnancy rates among women with evidence…
- Trial name
- NCT01662466
- Testing
- Testosterone cream (0.5mg per gram), DHEA
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Center for Human Reproduction
the Application of Time-lapes System in IVF/ICSI
The Application of Time-lapse System in IVF/ICSI
Nowadays, the rapid development of human assisted reproductive technology (ART) has provided many help for couples with fertility issues.
- Trial name
- NCT02974517
- Testing
- EmbryoScope®
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Infertility
Early Luteal Progesterone Profile After hCG Triggering
This pilot-study will help characterize the serum progesterone profiles in IVF patients and correlate progesterone levels to ovarian follicles obtained after stimulation with exogenous gonadotropins.
- Trial name
- NCT02798146
- Testing
- blood collection
- Volunteers
- 20 people
- Sponsor
- Vietnam National University
Preterm Birth, Gestational Diabetes Mellitus (GDM)
Evaluation of Maternal and Neonatal Outcomes in Women Are Conceived Through Assisted Reproductive Technology Compared to Other Fertility Treatments and Naturally Conceived Women: It is a Retrospective Cohort Study Conducted Over a 5-year Period at a Fertility Center in a Lebanese Hospital
Background: The number of couples experiencing difficulties conceiving and seeking treatment for infertility has increased dramatically over time.
- Conditions
- Preterm Birth, Gestational Diabetes Mellitus (GDM), Gestational Hypertension
- Trial name
- non (NCT06836843)
- Testing
- Since this is an observational study rather than an interventional study, the exposure type refers to all potential factors influencing pregnancy both before and during pregnancy
- Where
- Lebanon
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Lebanese University
Recurrent Implantation Failure
Role of Atosiban in Recurrent Implantation Failure
ET is the final stage of IVF which independently influences the treatment outcome. Successful embryo implantation is dependent on uterine receptivity.
- Trial name
- RIF (NCT04118959)
- Where
- Bahrain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
Ivf
Opt-IVF for Personalized Medicine for Normal Responders
A clinical trial will determine the effectiveness of the Opt-IVF decision-support tool in generating personalized, optimal drug-dosage profiles for each patient in the United States.
- Trial name
- NCT07856082
- Testing
- Opt-IVF, control
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Urmila DIwekar
Infertility (IVF Patients), Infertility
Intra-ovarian CAPA-IVM vs Standard IVM
This prospective study compares two approaches to obtaining mature oocytes for fertility treatment within the same participant. Immature oocytes are first retrieved from the right ovary and matured in the laboratory using a…
- Conditions
- Infertility (IVF Patients), Infertility, Infertility Female
- Trial name
- IO-CAPA (NCT07858435)
- Testing
- CAPA-IVM, In-House CAPA-IVM Pre-Maturation Medium, Minimal-Stimulation OS-IVF
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- New Hope Fertility Center
In Vitro Fertilization
Methylprednisolone Addition in IVF Treatment of Infertile Couples
Hypothesis to be tested is whether follicular addition of Methylprednisolone can efficiently control late follicular progesterone rise during IVF treatment
- Trial name
- NCT01220791
- Testing
- In vitro fertilization treatment for infertility
- Where
- Greece
- Volunteers
- 130 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility
A Trial Evaluating Autologous Endometrial Co-Culture Versus Conventional Medium in the Treatment of Infertility
One of the main factors in the success of in-vitro fertilization is the quality of the environment of the embryo. In contrast to maternal age, the environment in which the embryo develops is a modifiable factor.
- Trial name
- OvoGEN (NCT01886118)
- Testing
- Endometrial biopsy, Autologous Endometrial Co-Culture, Conventional media culture
- Where
- Canada
- Volunteers
- 207 people
- Sponsor
- Clinique Ovo
Tubal Obstruction
Hysteroscopic Versus Laparoscopic Tubal Occlusion in Cases of Hydrosalpinx and Planning for IVF
compare the efficacy of hysteroscopic tubal occlusion versus laparoscopic tubal occlusion for the patients of communicating hydrosalpinx scheduled for IVF.
- Trial name
- NCT04037813
- Testing
- Laparoscopic and hysteroscopic tubal occlusion for hydrosalpinx
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Cairo University
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