Clinical trials: Ivf
Infertility
Microfluidic Chip Method Versus Density-gradient Centrifugation Method in IVF
Infertile patients attending IVF treatment at the Centre of Assisted Reproduction and Embryology, Queen Mary Hospital and Kwong Wah Hospital will be recruited during ovarian stimulation for IVF.
- Trial name
- NCT06005311
- Testing
- Microfluidic chip, Density-gradient centrifugation
- Where
- China
- Volunteers
- 1,136 people
- Sponsor
- Professor Ernest Hung-Yu Ng
Infertility
In Vitro Fertilization (IVF) and Acupuncture for Infertility
The aim of this investigation is to determine the value of combining acupuncture with infertility patients undergoing In Vitro Fertilization (IVF).
- Trial name
- NCT00736411
- Testing
- acupuncture, IVF
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Pacific Fertility Center
Infertility, Infertility, Male
Randomized, Standard-Controlled, Study to Evaluate the Ohana IVF Sperm Preparation Kit, SPeRtility IVF Next Generation
Multi-centered, randomized controlled study, evaluating the safety and efficacy of the Ohana IVF Sperm Preparation Kit vs. a standard IVF sperm preparation kit.
- Trial name
- SPRING (NCT04142112)
- Testing
- Ohana IVF Sperm Preparation Kit (OHB035), Standard IVF Preparation Kit (OHB037)
- Where
- 7 sites in United States
- Volunteers
- 83 people
- Sponsor
- Ohana BioSciences
Pregnancy
Cervical Pessary vs. Vaginal Progesterone for Preventing Premature Birth in IVF Twin Pregnancies
To compare the effectiveness of cervical pessary (Arabin) and vaginal progesterone for preventing premature birth in twin pregnancies after IVF
- Trial name
- NCT02623881
- Testing
- Cervical pessary, Vaginal progesterone
- Where
- Vietnam
- Volunteers
- 300 people
- Sponsor
- Vietnam National University
Infertility/Sterility
Positive Adjustment Coping Intervention
Involuntary childlessness is experienced as emotionally stressful, however psychosocial counseling is not always available on the spot.
- Trial name
- PACI (NCT03118219)
- Testing
- Positive adjustment coping intervention, Brainteaser
- Where
- Germany
- Volunteers
- 401 people
- Sponsor
- University Hospital Heidelberg
IVF, Frozen Embryo Transfer
Lipiodol Prior to FET (LIFE)
Lipiodol® flushing is an effective fertility treatment for women with unexplained infertility. It is speculated that the treatment effect could work through a direct effect of Lipiodol® on the endometrium.
- Conditions
- IVF, Frozen Embryo Transfer, Hysterosalpingography
- Trial name
- LIFE (NCT06563908)
- Testing
- Lipiodol® uterine treatment prior to IVF/ICSI
- Volunteers
- 784 people
- Sponsor
- Mỹ Đức Hospital
Infertility, Infertility, Female
Serum Progesterone Levels on the Day of Frozen Embryo Transfer (FET) and Pregnancy Outcomes
Frozen embryo transfer (FET) cycles have become more common in recent years due to a push towards elective single embryo transfer (SET).
- Conditions
- Infertility, Infertility, Female, IVF
- Trial name
- ProFET (NCT04170517)
- Testing
- Measurement of serum progesterone on the day of FET
- Where
- United Kingdom
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- CARE Fertility UK
Infertility, COVID
Detection of SARS-CoV-2 in Follicular Fluid and Cumulus-oocyte-complexes in COVID-19 Patients
Recently, the world was shaken awake by a pandemic caused by a novel coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2).
- Conditions
- Infertility, COVID, IVF
- Trial name
- COVID_OFF (NCT04425317)
- Testing
- Blood sample
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- CRG UZ Brussel
HIV
HIV Physician's Survey
This is a survey study to assess the variability in the current management of pregnancy, reproductive care and assisted reproductive technologies for HIV-positive individuals in Canada to estimate interest for further projects.
- Trial name
- NCT01104974
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Infertility
Communication With in Vitro Fertilization (IVF) Patients About Risks
The primary objective of this trial is to determine whether written educational materials plus brief education by telephone will help patients better understand and participate in the decision on how many embryos to transfer to…
- Trial name
- NCT00722618
- Testing
- Written materials, telephone based education, Written materials
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- University of Kansas Medical Center
Fertilization in Vitro
Poor Ovarian Responders Undergoing IVF Using Luteal Ovarian Stimulation Versus Follicular Ovarian Stimulation
The investigators attempted to compare the clinical outcomes and cumulus genes expression in poor ovarian responders undergoing luteal ovarian stimulation or follicular ovarian stimulation in in vitro fertilization cycles.
- Trial name
- NCT03238833
- Testing
- luteal ovarian stimulation, follicular ovarian stimulation
- Where
- Taiwan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Ovarian Hyperstimulation Syndrome
The Use of GnRH Agonist Trigger in the Prevention of OHSS
To compare the incidence of ovarian hyperstimulation syndrome (OHSS) and implantation rate between high responder patients using Gonadotropin releasing GnRH) agonist or human chorionic gonadotropin (hCG) to trigger final oocyte…
- Trial name
- NCT00349258
- Testing
- Leuprolide acetate
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Infertility
A Phase IV, Prospective, Observational, Open Label, Single Centre Cohort Trial to be Conducted in Norway During One Year to Assess the Cumulative Pregnancy Rate in a New Series of In-vitro Fertilization (IVF) Treatment Cycles Following Three or More Previous IVF Treatment Cycles Without Live Birth
The primary objective of this observational study is to assess the cumulative rate of ongoing pregnancy at 10 ±2 weeks after hCG administration in a new series of IVF-treatment cycles in a total of 176 subjects, who have…
- Trial name
- NCT01071148
- Where
- Norway
- Volunteers
- 166 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Polycystic Ovary Syndrome
IVF Outcome in Polycystic Ovary Syndrome Patients
1. To investigate the circulating concentrations of phoenixin and their associations with BMI, the concentrations of sex hormones including (LH), (FSH), (E2), (P4), (TT) and steroid hormones enzyme in PCOS patients. 2.
- Trial name
- NCT04104958
- Testing
- qRTPCR (mRNA level).
- Volunteers
- 100 people
- Sponsor
- Assiut University
Infertility, Oocytes
Efficacy of a Simulator Based (PickUpSimTM) Residents' Training Program for Oocyte Retrievals
Simulation is an educational approach that has recently found an application in healthcare.acquire. Angers university hospital has decided to acquire, in December 2016, the high-fidelity Oocyte Pick up (OPU) simulator…
- Conditions
- Infertility, Oocytes, Fertilization in Vitro
- Trial name
- NCT03700255
- Testing
- PickUpSimTM simulation training program
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Infertility, Infertility, Male
Laser-Assisted Versus Conventional Intracytoplasmic Sperm Injection
Laser-assisted intracytoplasmic sperm injection (ICSI) has been suggested as a more effective alterative to conventional ICSI when this method of insemination is indicated for patients undergoing in vitro fertilization (IVF).
- Trial name
- NCT00114725
- Testing
- Laser-assisted intracytoplasmic sperm injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Ovarian Response
Human Chorionic Gonadotropin (hCG) Priming Prior to Controlled Ovarian Hyperstimulation (COH) in Poor Responder In Vitro Fertilization (IVF) Patients
There is a decline in androgen concentration with ovarian aging. Also, ovarian response to COH in IVF cycles diminishes with ovarian aging.
- Trial name
- APPE (NCT00870025)
- Testing
- human chorionic gonadotropin
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- IVI Madrid
Infertility, Recurrent Pregnancy Loss
Microfluidics Versus Gradient Centrifugation Effect on Euploidy Rates
This research is being done to determine if using a microfluidics chamber, a device used to process sperm, will be effective in improving the rates of embryos with normal chromosomes (structures that carry genetic information)…
- Trial name
- NCT04744025
- Testing
- Microfluidics chamber, Density Gradient Centrifugation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Lawrence Engmann
Menopause, Hypertension
Pituitary Derived-Intermedin is an Estrogen-Modulated Factor for Reducing Blood Pressure
Calcitonin, calcitonin gene-related peptides (CGRPs), adrenomedullin, and amylin belong to a unique group of peptide hormones important for the regulation of calcium balance, neurotransmission, cardiovascular homeostasis, and…
- Trial name
- NCT00133783
- Testing
- intermedin
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Infertility
Low-dose GH Supplementation Increases Clinical Pregnancy Rate
The objective of this study is to assess whether a low dose of GH supplementation (0.5 IU/day) increases clinical pregnancy rates in women with a history of POR who failed to become pregnant in two previous IVF cycles.
- Trial name
- NCT02359695
- Testing
- Growth Hormone
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Centro de Infertilidad y Reproducción Humana
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