Clinical trials: Ivf
Infertility
Use of Granulocyte Colony-stimulating Factor for the Treatment of Recurrent Implantation Failure in IVF Patients
The investigators use granulocyte colony-stimulating factor (GCSF) for the treatment of recurrent implantation failure in IVF patient with cause unknown or due to thin endometrium.
- Trial name
- NCT01315470
- Testing
- neupogen administration for women with recurrent IVF failure
- Where
- 2 sites in Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
The Serum Native Thiol (NT), Total Thiol (TT)
Effect of Thiol-Disulfide Homeostasis and Ischemia-Modified Albumin Levels on IVF Results in Male Factor Infertility
Thiol-disulfide Homeostasis (TDH) is essential for physiological functions in the human reproductive system, including antioxidant defense, detoxification, signal transduction, enzymatic regulation, apoptosis, and cellular…
- Conditions
- The Serum Native Thiol (NT), Total Thiol (TT), Serum Disulfide/TT Ratio, NT/TT Ratio
- Trial name
- IVF (NCT07033429)
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Duzce University
Infertility
Preimplantation Genetic Screening in IVF Treatment
This is the pilot phase of a randomised controlled trial. The purpose of the pilot study is to assess the ability to recruit, randomise, adherence to the study protocol and plan for a full study.
- Trial name
- PGSINIVF (NCT05009745)
- Testing
- PGT-A Strategy
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King's College London
Infertility
IUI vs. IVF/ICSI in Women Aged 38-42 Years: a Prospective Randomized Controlled Trial.
Prospective randomised controlled trial: 3 IUI cycles versus 1 IVF/ICSI cycle in women aged 38-42 years.
- Trial name
- NCT01992731
- Testing
- Drug: Follitropine Bèta
- Where
- Belgium
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
IVM, IVF
Children Born From IVM-CAPA vs IVF or Natural Conception
CAPA-IVM is a new promising IVM technique involving the use of a new compound to facilitate the oocyte and embryo competence. CAPA-IVM preserved the maintenance of trans-zonal projections and significantly improved maturation…
- Trial name
- NCT04048486
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Mỹ Đức Hospital
Children Born After Assisted Reproductive Technologies, Health Status
Health Status of Children Born After Assisted Reproductive Technologies
The goal of this observational study is to study the features of psychophysical development and the morbidity patterns of children born after assisted pregnancy, and to identify the connection with the health status of mothers…
- Conditions
- Children Born After Assisted Reproductive Technologies, Health Status, Child Development
- Trial name
- NCT06094998
- Testing
- hemogram examination
- Where
- Kazakhstan
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Kazakhstan's Medical University "KSPH"
Controlled Ovarian Stimulation
Trial to Assess the Pattern of Use of REKOVELLE® in Women Undergoing In Vitro Fertilisation (IVF) or Intracytoplasmic Sperm Injection (ICSI) Procedures in Routine Clinical Practice
Study designed to observe the usage patterns, efficacy and safety of REKOVELLE® in women naive to IVF and ICSI, undergoing their first Controlled Ovarian Stimulation (COS) treatment cycle with REKOVELLE® in routine clinical…
- Trial name
- NORSOS (NCT05499052)
- Testing
- REKOVELLE®
- Where
- 9 sites in Denmark, Norway and 2 more
- Volunteers
- 201 people
- Sponsor
- Ferring Pharmaceuticals
COVID-19, IVF
The Impact of the Previous Exposure to Covid-19 Virus Infection on the Outcome of ICSI Cycles
Whilst the global COVID-19 pandemic is still evolving and there are many unknowns about the long-term effects of the virus on fertility and pregnancy, we found ourselves in need to offer some evidence-based guidance, that's why…
- Trial name
- NCT05198401
- Testing
- covid-19
- Where
- Egypt
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
Anti-Müllerian Hormone, Polycystic Ovarian Syndrome
Clinical Application of Serum Anti-Müllerian Hormone (AMH) Measurements
This study aims to assess the association of Anti-Müllerian hormone (AMH) with polycystic ovarian syndrome, premature ovarian insufficiency and fertility. The main objectives include the following: 1.
- Conditions
- Anti-Müllerian Hormone, Polycystic Ovarian Syndrome, Premature Ovarian Insufficiency, Fertility Issues
- Trial name
- NCT05858307
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- Chinese University of Hong Kong
Infertility, IVF
The Importance of Embryo Transfer Day Progesterone Value in Natural Cycle Frozen Embryo Transfers and the Evaluation of the Effect of Rescue Therapy on Pregnancy Outcomes in Patients With Low Progesterone Levels
Thanks to recent advances in clinical practice and laboratory, embryo cryopreservation has become the first-line procedure in assisted reproductive technology.
- Conditions
- Infertility, IVF, Progesterone
- Trial name
- NCT05481684
- Testing
- Normal Progesterone group, Low Progesterone group
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
IVF, Intracytoplasmic Sperm Injection
Buscopan in Patients Undergoing IVF/Intracytoplasmic Sperm Injection Treatment
To determine if the use of Buscopan in patients undergoing IVF/ICSI treatment with high uterine contraction frequency prior to embryo transfer has a higher live birth rate.
- Trial name
- NCT04751084
- Testing
- Buscopan 20 milligrams/ML Injectable Solution
- Where
- Hong Kong
- Volunteers
- 675 people
- Sponsor
- Chinese University of Hong Kong
Androgen Profile, Inflammatory Markers
Effect of Resveratrol on Metabolic Parameters and Oocyte Quality in PCOS Patients
Polycystic ovary syndrome (PCOS) is characterized by enlarged ovaries, menstrual irregularity and hyperandrogenism and is the most common cause of oligoovulatory infertility.
- Conditions
- Androgen Profile, Inflammatory Markers, IVF Outcome
- Trial name
- RES-IVF (NCT01782911)
- Testing
- Resveratrol
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Mayer-Rokitansky-Kuster Syndrome, Asherson's Syndrome
INvestigational Study Into Transplantation of the Uterus
Observational study on cohort of 10 women undergoing uterine transplantation using deceased donors
- Conditions
- Mayer-Rokitansky-Kuster Syndrome, Asherson's Syndrome, Postpartum Hemorrhage, Cervical Cancer
- Trial name
- INSITU (NCT04244409)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Womb Transplant UK
Fertilization in Vitro
Optimizing the Technique of Embryo Transfer in IVF Using Better Imaging Guidance
This trial seeks to improve ultrasound imaging during embryo transfer in IVF by using a small, high resolution ultrasound probe used routinely for cardiac imaging in children.
- Trial name
- NCT03062098
- Testing
- ultrasound imaging
- Where
- Israel
- Sponsor
- Rambam Health Care Campus
Infertility
Effect of Endometrial Thickness on IVF Outcome
Although many studies have evaluated the relationship between endometrial thickness and IVF outcome, the results are still controversial.
- Trial name
- NCT02420704
- Testing
- Embryo transfer
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Infertility
A Study to Evaluate the Ease of Use, Local Tolerance, Safety and Effectiveness of Gonal-f® (Filled-by-mass in a Prefilled Pen)
This is a prospective, open-label, non-comparative, multicentric Phase 4 study to evaluate the ease of use, local tolerance, safety and effectiveness of Gonal-f® (filled-by-mass in a prefilled pen) in subjects undergoing ovarian…
- Trial name
- NCT01115725
- Testing
- Gonal-f® (follitropin alfa)
- Where
- Greece
- Volunteers
- 76 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility, In Vitro Fertilization
Patients' Preference for Subcutaneous or Vaginal Progesterone as Luteal Support in IVF/ICSI Cycles
This randomized, controlled, prospective, crossover, open-label, two-treatments, two-period trial aimed to evaluate the preference expressed by the patient concerning the subcutaneous administration of progesterone versus the…
- Trial name
- NCT03181685
- Testing
- Progesterone 25 MG subcutaneous, Micronized progesterone 200 MG, recombinant FSH
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Andros Day Surgery Clinic
Infertility, Female
Androgenic Profile Following Controlled Ovarian Stimulation
In this study the investigators will try to discover whether there is a difference for any of the stimulation preparations - recombinant FSH + recombinant LH (pergoveris \& luveris) vs.
- Trial name
- NCT02992808
- Testing
- recombinant gonadotropins, HP-HMG
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Fertilization in Vitro
The Comparison of Granulosa Cell Apoptosis Rates With or Without Luteinizing Hormone Administration in Poor Responders.
In Zeynep Kamil Women and Children's Education and Research Hospital which is a tertiary referral hospital, the investigators perform microdose flare-up gonadotropin-releasing hormone (GNRH) analogue or GNRH antagonist protocol…
- Trial name
- NCT03527823
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sebnem Alanya Tosun
Infertility (IVF Patients)
Iodine Supplementation and Fertility Parameters
Iodine has been identified as a potential factor influencing female fertility during the childbearing years. The American Thyroid Association recommends that women attempting to conceive take a supplement containing 150 µg of…
- Trial name
- NCT06721273
- Testing
- Iodine
- Volunteers
- 230 people
- Sponsor
- Tehran University of Medical Sciences
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