Clinical trials: Ivf
IVF, GnRH Antagonist
Live Birth Rate Between PPOS and GnRH Antagonist Protocol in Patients With Anticipated High Ovarian Response
Progestin can inhibit the pituitary LH surge during ovarian stimulation and various studies show progestin-primed ovarian stimulation (PPOS) is effective in blocking the LH surge in IVF.
- Conditions
- IVF, GnRH Antagonist, PPOS
- Trial name
- NCT04414761
- Testing
- Progesterone, GnRH Antagonist
- Where
- China
- Volunteers
- 784 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Progesterone, Luteal Phase Support
Patient's Preferences About Subcutaneous or Vaginal Progesterone Administration for Luteal Phase Support
Luteal phase support in "in vitro fertilization" (IVF) cycles has been shown to improve pregnancy rates and became a standard of treatment, and progesterone is the first choice considering its safety profile and effectiveness.
- Conditions
- Progesterone, Luteal Phase Support, In Vitro Fertilization
- Trial name
- PROPER-1 (NCT03734770)
- Testing
- Subcutaneous Progesterone, Vaginal progesterone
- Where
- Italy
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Miscarriage
Serum Kisspeptin: a Predictive Marker of Miscarriage or Not?
This is a prospective observational study. Eligible women undergo ART treatment in our centre will be recruited for the study and each woman will only be included in the study once. Informed written consent will be obtained.
- Trial name
- NCT03940495
- Where
- China
- Volunteers
- 182 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
In Vitro Maturation of Oocytes
Fertilo In Vitro Research Study and Trial
The goal of this clinical trial is to evaluate the safety and efficacy of using Fertilo for In vitro maturation (IVM) in participants 18-35 years of age.
- Trial name
- FIRST (NCT06858111)
- Testing
- Fertilo, Medicult IVM
- Where
- 16 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Gameto, Inc.
Male Infertility
Andrositol® TEST as Diagnostic Assay to Predict the Fertilization Potential in IVF
Andrositol® test allows to obtain additional information besides the WHO parameters and to evaluate the semen energetic status. The diagnosis is performed by analyzing the semen at two different time points: before the treatment…
- Trial name
- NCT03677011
- Testing
- Andrositol® Test
- Where
- United States
- Volunteers
- 249 people
- Sponsor
- Lo.Li.Pharma s.r.l
Recurrent Implantation Failure
Platelet Rich Plasma and Recurrent Implantation Failure
This study is a randomized controlled clinical trial to compare the pregnancy outcomes of infertile women with recurrent implantation failure.
- Trial name
- NCT03996837
- Testing
- Intra uterine infusion of platelet rich plasma
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Infertility, Female, Thrombophilia
Effect of Prophylatic Use of Enoxaparin in Women Undergoing in Vitro Fertilization Treatment
Retrospective study designed to evaluate outcomes in patients undergoing assisted reproduction. Some of them had thrombophilia, and part of them was treated with enoxaparin, started on the day of embryo transfer, and the other…
- Conditions
- Infertility, Female, Thrombophilia, Fertilization in Vitro
- Trial name
- NCT05225155
- Testing
- Enoxaparin
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Faculdade de Medicina do ABC
Female Reproductive Problem, Male Reproductive Problem
Assisted Reproductive Technology Survey (ART Survey)
The purpose of the study is to collate local information to better understand the motivations, accessibility and frequency of assisted reproductive technology (ART) use in the community.
- Trial name
- ART (NCT02249390)
- Where
- United States
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Infertility, Pregnancy
Improvement of IVF Fertilization Rates, by the Cyclic Tripeptide FEE - Prospective Randomized Study
cFEE peptide improves the IVF fertilization rate in mouse and fertilization index in human. It improves sperm movement's parameters. It has been studied over 3 generations of mice and appears without any side effects.
- Trial name
- Fertiline (NCT02161861)
- Testing
- cFFE increase the fusiogenic capacities of a gamete
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility (IVF Patients)
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.
The goal of this multicenter, randomized, placebo-controlled, double-blind clinical trial is toto evaluate the efficacy and safety of a human menopausal gonadotropin (hMG) in the development of multiple follicles, pregnancy, and…
- Trial name
- GRACE (NCT07216742)
- Testing
- hMG subcutaneous injection
- Where
- 16 sites in United States
- Volunteers
- 659 people
- Sponsor
- Granata Bio Corporation
Embryo Selection, IVF
Embryo Selection by Metabolomic Profiling of Embryo Culture Medium With Mass Spectroscopy as an Adjunct to Morphology
Identification of the embryo with the highest potential to implant and establish an ongoing pregnancy is a primary aim in human assisted reproduction.
- Conditions
- Embryo Selection, IVF, Morphology
- Trial name
- NCT02698488
- Testing
- Morphology, Morphology and Mass Spectroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Istanbul University
Infertility
Autologous Endometrial Coculture (AECCT)
The purpose of this study is to determine if the use of Autologous Endometrial Coculture (AECC) in young in vitro fertilization (IVF) patients with poor ovarian reserve improves pregnancy outcome.
- Trial name
- AECCT (NCT01472861)
- Testing
- AECC (Autologous endometrial coculture), no endometrial biopsy or Autologous endometrial coculture (AECC) performed
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Diminished Ovarian Reserve, Infertility
Delayed Start to Ovarian Stimulation
In couples with infertility secondary to Diminished Ovarian Reserve, the investigators hypothesize that a delayed start (7 day) to ovarian stimulation with an GnRH antagonist (Ganirelix) will improve oocyte maturation and…
- Conditions
- Diminished Ovarian Reserve, Infertility, In Vitro Fertilization
- Trial name
- DOS/DOR (NCT01614067)
- Testing
- Ganirelix acetate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Cognitive Behavioral Therapy, Hormone Disturbance
Effectiveness of CBT in Improving Psycho-Neuro-Endocrine Factors in Women Following In Vitro Fertilization Program
The goal of this clinical trial is to learn if Cognitive Behavioral Therapy (CBT) can improve psychological, neurological, and hormonal aspects in women undergoing In Vitro Fertilization (IVF).
- Conditions
- Cognitive Behavioral Therapy, Hormone Disturbance, In Vitro Fertilization
- Trial name
- NCT06521957
- Testing
- Cognitive Behavioral Therapy
- Where
- Indonesia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Infertility
The Impact of Acupuncture on the Success Rates of IVF (In Vitro Fertilisation) Treatments
The trial aims to investigate whether acupuncture has an effect in increasing clinical pregnancy (pregnancy that is confirmed by a scan) and live birth rates on women undergoing IVF treatment.
- Trial name
- NCT02683967
- Testing
- acupuncture
- Volunteers
- 184 people
- Sponsor
- Homerton University Hospital NHS Foundation Trust
Embryo Culture, Embryo Culture Media
Evaluation of an Undisturbed Embryo Culture System for Embryo Development in IVF/ICSI Cycles
This is a prospective, multicenter, randomized controlled clinical trial designed to evaluate whether a fully undisturbed closed embryo culture system can improve the developmental potential of embryos cultured in vitro and…
- Conditions
- Embryo Culture, Embryo Culture Media, Embryo Quality
- Trial name
- Embryos UECS (NCT07522281)
- Testing
- Gems FEM fertilization medium + Geri incubator+Gems one-step medium, Vitrolife fertilization medium+benchtop incubator + Vitrolife sequential culture media
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Periodontitis, Sub-fertility
Association Study Between Periodontal Disease and Male Infertility
The aim of the present study is to examine the association between fertility parameters and the periodontal status of men attending fertility and in vitro fertilization clinic.
- Trial name
- NCT01140945
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Male Infertility
Spermatozoa Morphology Selection by Thermotaxis
This study aims to eventually assess the usefulness of thermotaxis for sperm selection in routine clinical practice.
- Trial name
- NCT04849156
- Testing
- Sperm selection by thermotaxis
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Male Infertility, Infertility, Male
The Evaluation of the Effect of Microfluidic Sperm Sorting Chip 'Labs-on-a-chip' on IVF Success in Male Factor
Microfluidic chips are one of the methods of sperm separation to eliminate DNA fragmentation in sperm. It is thought that the separation of sperm by centrifugation in the classical gradient density (Percoll) method used in sperm…
- Trial name
- NCT03960229
- Testing
- MicroFluidic Sperm Sorting Chips, Gradient-Density Centrifugation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Female Urogenital Diseases
The Effect of Laser-assisted Zona Thinning on the Implantation Rate in the Women of Advanced Age
The purpose of this study is to determine whether laser-assisted zona thinning improve the implantation rate of the women of advanced age in the first IVF/ICSI cycles
- Trial name
- NCT01765322
- Testing
- ZILOS-TK IVOS Analyzer
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shanxi Provincial Maternity and Children's Hospital
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