Clinical trials: Ivf
Fetal Sex Determination
Evaluation of Fetal Sex in Assisted Reproductive Technology (ART) Achieved Pregnancies
Whole blood and urine samples will be collected from pregnant woman of gestational age 36-56 days as confirmed by artificial reproductive technology (ART).
- Trial name
- PREVIEW (NCT01021085)
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Sequenom, Inc.
Infertility
Luteal Phase FSH in the IVF Poor Responder
In vitro fertilization (IVF) is a common procedure used to assist couples who have difficulty conceiving a pregnancy. IVF is a process where oocytes (eggs) are retrieved from a woman's ovaries and fertilized with sperm in the…
- Trial name
- NCT00225433
- Testing
- follitropin beta, ganirelix acetate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Male Infertility, Leukopenia
Male Infertility Related With Post Infection Inflammatory Syndrome
BACKGROUND: One couple out of 6 consults for infertility during their sexual life. In 60% of cases a male factor is associated or is the main infertility factor.
- Conditions
- Male Infertility, Leukopenia, Postinfection Inflammation, Oxidative Stress
- Trial name
- SIGMA (NCT01407484)
- Testing
- Prednisone
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility (IVF Patients), Embryo Morphokinetics
IVF Outcomes With Time-Lapse Culture: Comparison Between PPOS and GnRH Antagonist Protocols
The goal of this clinical trial is to compare two ovarian stimulation protocols used in in vitro fertilization (IVF): the fixed Progestin-Primed Ovarian Stimulation (PPOS) protocol and the GnRH Antagonist protocol.
- Conditions
- Infertility (IVF Patients), Embryo Morphokinetics, Progestins Primed Ovarian Stimulation
- Trial name
- NCT07409493
- Testing
- Progestin-Primed Ovarian Stimulation, Antagonist protocol for IVF
- Where
- Vietnam
- Volunteers
- 148 people
- Sponsor
- Hanoi Medical University
Infertility
Derivation of New Human Embryonic Stem Cell Lines Lines for Clinical Use
Human embryonic stem cells (hESCs) are isolated from the early human embryo and have the capability to proliferate indefinitely in culture and to develop into nearly every cell of the human body.
- Trial name
- NCT00353197
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
IVF, Infertility
Desogestrel Versus GnRH Antagonist in IVF/ICSI
Progestin primed ovarian stimulation (PPOS) has been shown to be effective in avoiding premature spontaneous ovulation, without affecting the number of retrieved oocytes or the quality of the embryos obtained.
- Trial name
- DEGOS (NCT04728659)
- Testing
- Desogestrel 0.075 MG, Orgalutran
- Where
- Italy
- Volunteers
- 165 people
- Sponsor
- Casa di Cura Privata Villa Mafalda
Infertility
In Vitro Maturation (IVM) of Human Oocytes
The objectives of this study are to evaluate the clinical efficacy of Natural in vitro Fertilization and in vitro maturation.
- Trial name
- IVM (NCT01550861)
- Testing
- in vitro maturation, Polar Body Biopsy with preimplantation genetic screening
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Subfertility
Letrozole in Stimulated IVF Cycles
In-vitro fertilization (IVF) is the treatment of choice for couples with prolonged infertility. The treatment usually involves hormonal stimulation of the ovaries by follicle stimulating hormone (FSH), followed by surgical…
- Trial name
- NCT02912988
- Testing
- Letrozole
- Where
- 2 sites in China
- Volunteers
- 900 people
- Sponsor
- The University of Hong Kong
IVF
Efficacy of Micronized Natural Progesterone vs GnRH Antagonist in the Prevention of LH Peak During Ovarian Stimulation.
This study aims to investigate if the use of oral micronized natural progesterone is not inferior to the use of subcutaneous antagonist in preventing LH peak in controlled ovarian stimulation.
- Trial name
- PRO_NAT (NCT05954962)
- Testing
- Progesterone 200 MG, Ganirelix Acetate
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Women Suffering From Unilateral or Bilateral Tubal Occlusion Due to Hydrosalpinx
Use of Adiana Tubal Occlusive Devices in Women With Hydrosalpinx Prior to In Vitro Fertilization
A condition called hydrosalpinx occurs when one or both of the fallopian tubes is blocked with fluid. The fluid can leak into the tube and the uterus.
- Trial name
- NCT01224080
- Testing
- Adiana placement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Reproductive Science Center
Infertility Assisted Reproductive Technology
The Feasibility of taVNS on Pregnancy Outcomes of Infertility Patients Undergoing IVF
To assess the feasibility of taVNS on pregnancy outcomes of infertility subjects undergoing IVF, the primary aim of this trial will focus on encompassing recruitment, compliance, and preliminary engagement outcomes.
- Trial name
- NCT06742788
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xijing Hospital
IVF, Fertility Preservation
Micro RNA Profile in the Ovarian Follicle Fluid of Transgender Men
The effects of gender transitioning, particularly the effects of testosterone exposure in transgender men, on the oocyte and embryo development are largely unknown.
- Conditions
- IVF, Fertility Preservation, Infertility
- Trial name
- NCT03725280
- Testing
- IVF
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pregnancy, Immune Tolerance
Mechanisms of Maternal Immune Tolerance in Early Pregnancy
This study explores the mechanisms of maternal immune tolerance in early pregnancy by characterizing immune cell profiles and functional pathways during the first trimester.
- Conditions
- Pregnancy, Immune Tolerance, In Vitro Fertilization
- Trial name
- NCT07297394
- Testing
- Blood sampling
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Basel, Switzerland
Obesity
Effect of Hypocaloric Diet and Exercise in Obese Women Who Are Subjected to IVF Cycle
The purpose of this study is to determine the impact of diet and physical exercise program on pregnancy rate and live birth in obese women who undergo an IVF cycle.
- Trial name
- NCT01952795
- Testing
- Diet and exercise
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Simulation Training, IVf
Benefits of an Oocyte Pickup Simulation Training Program
The primary objective of this study was to evaluate oocyte pick up simulation training program for teaching residents. The secondary objectives were to evaluate resident satisfaction and the overall current state of oocyte pick…
- Conditions
- Simulation Training, IVf, Education
- Trial name
- NCT04130139
- Testing
- oocyte pick up simulator
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Infertility, Assisted Reproductive Technology
Microbiome and Metabolome Profiles in Couples Undergoing IVF and Reproductive Outcomes
This prospective observational cohort study investigates the role of the microbiome and metabolome in couples undergoing in vitro fertilization.
- Conditions
- Infertility, Assisted Reproductive Technology, Pregnancy Complications, Pregnancy Loss, Early
- Trial name
- Mi IVF (NCT07532629)
- Where
- 3 sites in Sweden
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Subfertility
Mild Versus Conventional Ovarian Stimulation Treatment for In Vitro Fertilization
In vitro fertilization (IVF) is an assisted reproductive technique to achieve pregnancy in subfertile couples of which the average success rate is only 25%.
- Trial name
- FOLFO (NCT00985062)
- Testing
- Mild Ovarian Stimulation Treatment, Conventional Ovarian Stimulation Treatment
- Where
- Netherlands
- Volunteers
- 54 people
- Sponsor
- Erasmus Medical Center
Hypo-responder, Infertility (IVF Patients)
Optimal Stimulation of Hypo-responders Undergoing in Vitro Fertilization (IVF)
Stimulation is a key step of in vitro fertilization (IVF). Typically, injectable gonadotropins are used for stimulation, and their dose is individually determined to avoid hypo- as well as hyper-response.
- Conditions
- Hypo-responder, Infertility (IVF Patients), OVARIAN STIMULATION
- Trial name
- NCT07121751
- Testing
- use of combination of recombinant FSH and recombinant LH, higher dose recFSH, unchanged dose
- Where
- 4 sites in Hungary
- Volunteers
- 150 people
- Sponsor
- Dunamenti REK Istenhegyi IVF Center
Infertility, Female, IVF
RCT to Assess the Impact of Microbiome Status in Infertile IVF Patients at Their First IVF/ICSI Cycle
Although the endometrium has been traditionally considered free of bacteria, recent studies have documented the presence of an endometrial microbiome.
- Trial name
- NCT04686357
- Testing
- EMMA/ALICE
- Volunteers
- 1,018 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Female Infertility, Embryo Development
Day-4 Embryo Defragmentation: Blastocyst Rate and clInical Outcomes
Background: Embryo fragmentation is one of the main morphological parameters assessed during in vitro culture in assisted reproductive technology (ART).
- Conditions
- Female Infertility, Embryo Development, In Vitro Fertilization
- Trial name
- DEBRIS (NCT07500337)
- Testing
- Mechanical embryo defragmentation at Day 4 (morula stage), Standard embryo culture without intervention
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- Momo Fertilife
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