Clinical trials: Ivf
Infertility, Female, Endometrial Diseases
Effect of Different Ovarian Stimulation Protocols on Endometrial Receptivity
This study will assess the change in endometrial gene expression signature on the day of embryo transfer according to the type of exogenous gonadotropins administered.
- Trial name
- NCT03755973
- Testing
- CFA, rFSH, Fixed daily rFSH dosing protocol of 200-300 IU
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Female Infertility Due to Diminished Ovarian Reserve
Use of Dehydroepiandrosterone (DHEA) in Women With Normal and Poor Ovarian Reserve Undergoing IVF
The aim of the study is to evaluate the effect of DHEA supplement on ovarian reserve markers, ovarian response to gonadotrophins and cycle outcomes in patients with normal and poor ovarian reserve. Study Hypotheses: 1.
- Trial name
- NCT01915186
- Testing
- Dihydroepiandrosterone (DHEA)
- Where
- Hong Kong
- Volunteers
- 104 people
- Sponsor
- The University of Hong Kong
Infertility
To Describe the Effect of rhLH Supplementation in Women With Hyporesponse to rhFSH After Pituitary Downregulation
Primary objective: To evaluate the efficacy in terms of oocyte retrieval number of rLH supplement in women with hyporesponse to rFSH after pituitary downregulation.
- Trial name
- NCT01029470
- Testing
- Luveris
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University Third Hospital
Female Infertility, Ovarian Insufficiency
Efficacy Study Comparing the Effect of Clomiphencitrate to an Antagonist Protocol
The aim of this study is to assess the oocyte yield of infertile women with suspected or known poor ovarian reserve (POR) undergoing a GnRH antagonist protocol for IVF with Merional® starting either with a low (150 IU) or a high…
- Trial name
- CANTAPOR (NCT01577472)
- Testing
- High Dose Clomiphencitrat, Low Dose Clomiphencitrat
- Where
- Switzerland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
In Vitro Fertilization
A Study to Investigate the Efficacy and Safety of a Single Injection of Corifollitropin Alfa (Organon 36286) for Ovarian Stimulation Using Daily Recombinant Follicle Stimulating Hormone (FSH) as Reference (P05787)
To investigate the efficacy and safety of a single injection of 150 μg Corifollitropin Alfa (Organon 36286) to induce multifollicular development for controlled ovarian stimulation using daily recombinant FSH (recFSH) as a…
- Trial name
- NCT00696800
- Testing
- Corifollitropin alfa, RecFSH / Follitropin beta (Days 1 to 7), RecFSH / Follitropin beta (Days 8 to hCG)
- Volunteers
- 1,509 people
- Sponsor
- Organon and Co
Vaginal Flora Imbalance
Vaginal Microbiome and IVF Pregnancy Outcome
The aim of this prospective, observational study is to investigate the prevalence of vaginal dysbiosis among women undergoing IVF procedures in the US.
- Trial name
- NCT05150639
- Testing
- IVF
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Freya Biosciences ApS
Infertility
Protocol to Minimize Injections and Blood Draws for Women Undergoing in Vitro Fertilization
The purpose of the study is to evaluate the safety and efficacy of nasal gonadotropins (Menopur) in women undergoing IVF. The purpose of this study is also to report and monitor any and all side effects of the nasal Menopur.
- Trial name
- NCT02865681
- Testing
- Menopur, Synarel, HCG trigger
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- New Hope Fertility Center
Implantation Failure
Effect of Fire-Needle Combined With Regular Acupuncture on Pregnancy Outcome in Patients With Recurrent Implantation Failure Undergoing In Vitro Fertilization
This study aims to evaluate whether fire-needle combined with regular acupuncture improves pregnancy outcomes in patients with recurrent implantation failure (RIF), compared to no or regular acupuncture.
- Trial name
- NCT07462754
- Testing
- no acupuncture, regular acupuncture, Fire needle combination group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Huazhong University of Science and Technology
PCOS
Effect of Laparoscopic Ovarian Drilling on Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women With Polycystic Ovary Syndrome
the polycystic ovarian syndrome is associated with an ovulation and infertility. recently the laparoscopic ovarian drilling has been used as surgical treatment for ovulation in women with polycystic ovarian syndrome, although its…
- Trial name
- NCT03527979
- Testing
- IVF/ICSI
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Ain Shams University
Male Infertility
Proposed Research Protocol For Male Infertility
The purpose of this experiment is to test the feasibility of a minimally interventionist protocol for young couples with male factor infertility, which addresses the cause of infertility for these couples which is the inability…
- Trial name
- NCT01255397
- Testing
- Male Infertility Protocol
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Infertility
IMPACT OF POLYCYCLIC AROMATIC HYDROCARBONS (PAH) ON IN VITRO FERTILIZATION
The main objective of this study is to highlight a relationship between exposure to PAHs, genotoxic effect biomarkers on spermatozoa and follicular cells, as well as embryonic quality and embryo implantation rates at a given…
- Trial name
- NCT03914859
- Testing
- IN VITRO FERTILIZATION
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Embryo Implantation
Assessment of Endometrial Receptivity in Recipients of Donated Oocytes
The purpose of this study is to determine whether endometrial receptivity markers obtained by endometrial sampling are effective in prediction of in vivo human embryo implantation.
- Trial name
- ERPOD (NCT00506480)
- Testing
- endometrial sampling
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Infertility
Evidence-based Stimulation Trial With Human rFSH in Europe and Rest of World 1
This trial investigates the effects of FE 999049 compared to GONAL-F.
- Trial name
- ESTHER-1 (NCT01956110)
- Testing
- Follitropin Delta (FE 999049), Follitropin Alfa (GONAL-F)
- Where
- 13 sites in Belgium, Brazil and 9 more
- Volunteers
- 1,329 people
- Sponsor
- Ferring Pharmaceuticals
Infertility
Injection of Hormone to Enhance Implantation in Embryo Transfer After IVF
The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.
- Trial name
- NCT01986374
- Testing
- HCG is introduced
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Servy Massey Fertility Insititute
Women Undergoing Fertility Treatments
The Use of PulseNmore FC Device in Patients Undergoing IVF Treatment A Study to Evaluate the Safety and the Efficacy
This is a single center, interventional, longitudinal prospective, of 100 women undergoing fertility treatment in the IVF unit of Belinson Hospital.
- Trial name
- NCT05485623
- Testing
- PulseNmore FC
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Healthy, PCOS
In Vitro Maturation of Human Eggs
CCRM Fertility, a global pioneer in fertility treatment, research and science, is seeking participants for a new study on in vitro maturation (IVM).
- Conditions
- Healthy, PCOS, PCOS (Polycystic Ovary Syndrome), Ovarian Reserve
- Trial name
- NCT06633120
- Testing
- IVM
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colorado Center for Reproductive Medicine
Infertility (IVF Patients)
Correlation of the Genetic Constitution of the Spent Blastocyst Media
The main objective of this study is to improve niPGT-A (non-invasive Preimplantation Genetic Testing for Aneuploidies) to avoid the need of a biopsy to perform the genetic analysis of the embryo and to help in understanding the…
- Trial name
- CONNECTED (NCT06780605)
- Testing
- niPGT-A, Multifocal TE biopsies and ICM biopsy
- Where
- 2 sites in Cyprus
- Volunteers
- 230 people
- Sponsor
- Igenomix
Women With Leiomyoma After at Least One Unsuccessful IVF Treatment
IVF Outcome Following Treatment With Ulipristal Acetate for Myomatous Uterus After at Least One IVF Failure
Hypothesis: After reviewing the relevant medical data the investigators assume that treating a woman with intramural fibroid not distorting the uterine cavity or mostly intramural with less than 50% submucosal component with…
- Trial name
- NCT02601196
- Testing
- Ulipristal acetate
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Infertility, Female
Comparison of in Vitro Fertilization Rates of Oocytes and Embryo Development Using Two Techniques of Semen Processing
The investigators propose to assess one method of sperm selection based on the characteristics of spermatozoa recently introduced: Sperm Selection Assay, which used a gradient of concentration of progesterone to act as…
- Trial name
- NCT03186170
- Testing
- SSA sperm selection
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
IVF
The Effect of Sildenafil Citrate on Frozen Embryo Transfer Cycles
to investigate the value of adding sildenafil citrate during endometrial preparation in patients undergoing frozen-thawed embryo transfer and its effect on endometrial thickness and pregnancy rates.
- Trial name
- NCT05951413
- Testing
- Sildenafil Citrate, estradiol
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
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